Desempenho de escolares com dislexia: programas de intervenção metalinguistico e de leitura

Dyslexia is specific learning disabilities, of neurological origin, resulted from a phonological deficit of language. This study aims to verify the performance of students with dyslexia in phonological intervention program, reading program, and phonological and reading remediation program in students with dyslexia. The participants of this study were 60 students who were divided as follows: GI (ten students with dyslexia submitted to phonological remediation program and ten students with dyslexia not submitted to phonological remediation program), GII (ten students with dyslexia submitted to reading program and ten students with dyslexia not submitted to reading program), GIII (ten students with dyslexia submitted to phonological and reading program and ten students with dyslexia not submitted to phonological and reading program). The phonological and reading remediation was applied in three phases: pretest, training, post-testing. The results showed significant statistical difference between two evaluation moments, revealed better performance in the cognitive-linguistic skills in post-test situation comparing to the pretest, showing the efficacy of the three remediation programs for students with dyslexia. The better performance of the students with dyslexia submitted to the remediation programs shows the necessity of phonological instruction or phonological instruction with reading to be offered in the literacy context, once this will help students to develop cognitive-linguistic skills to learn the alphabetic basis of the Brazilian Portuguese writing system.

Desempenho de crianças com deficiência auditiva e implante coclear em tarefas de seleção de e de nomeação de figuras

The aim of this study was to investigate the development of specific domains of Numerical Cognition (Number Sense – NS, Number Comprehension – NC, Number Production – NP, and Calculation – CA) in Brazilian children with Specific Learning Disorders. The study included 72 children (36 boys), from 9-to 10-years-old, enrolled in 4th and 5th years of elementary school of public schools at countryside of Sao Paulo State, Brazil. They were divided into three groups: control (CT, N = 42), Developmental Dyslexia (DL, N = 11) and Developmental Dyscalculia combined with dyslexia (DDc, N = 19). All participants had intellectual level within the normal range, however, children from the last two groups had Learning Disorders classified by School Achievement Test - TDE (Stein, 1994) and DDc children received necessarily classification as 'inferior' in Arithmetic Test of TDE. The children did not differ in NS. DL and DDc children showed slight deficits in NC. However, DDc children had moderate in NP and mild to moderate deficits in CA, which indicates a more generalized impairment in Numerical Cognition. Furthermore, DDc children showed discrepancy in Numerical Cognition performance when compared to the other groups. Thus, children with Learning Disorders showed different performances in Numerical Cognition, although both groups had preserved SN, DDc children showed higher deficits and discrepancy in relation DL and typically developing children.

Effects of environmental complexity on neurogenesis in the hippocampal dentate gyrus

Introduction. Postnatal neurogenesis in the hippocampal dentate gyrus, can be modulated by numerous determinants, such as hormones, transmitters and stress. Among the factors positively interfering with neurogenesis, the complexity of the environment appears to play a particularly striking role. Adult mice reared in an enriched environment produce more neurons and exhibit better performance in hippocampus-specific learning tasks. While the effects of complex environments on hippocampal neurogenesis are well documented, there is a lack of information on the effects of living under socio-sensory deprivation conditions. Due to the immaturity of rats and mice at birth, studies dealing with the effects of environmental enrichment on hippocampal neurogenesis were carried out in adult animals, i.e. during a period of relatively low rate of neurogenesis. The impact of environment is likely to be more dramatic during the first postnatal weeks, because at this time granule cell production is remarkably higher than at later phases of development. The aim of the present research was to clarify whether and to what extent isolated or enriched rearing conditions affect hippocampal neurogenesis during the early postnatal period, a time window characterized by a high rate of precursor proliferation and to elucidate the mechanisms underlying these effects. The experimental model chosen for this research was the guinea pig, a precocious rodent, which, at 4-5 days of age can be independent from maternal care. Experimental design. Animals were assigned to a standard (control), an isolated, or an enriched environment a few days after birth (P5-P6). On P14-P17 animals received one daily bromodeoxyuridine (BrdU) injection, to label dividing cells, and were sacrificed either on P18, to evaluate cell proliferation or on P45, to evaluate cell survival and differentiation. Methods. Brain sections were processed for BrdU immunhistochemistry, to quantify the new born and surviving cells. The phenotype of the surviving cells was examined by means of confocal microscopy and immunofluorescent double-labeling for BrdU and either a marker of neurons (NeuN) or a marker of astrocytes (GFAP). Apoptotic cell death was examined with the TUNEL method. Serial sections were processed for immunohistochemistry for i) vimentin, a marker of radial glial cells, ii) BDNF (brain-derived neurotrofic factor), a neurotrophin involved in neuron proliferation/survival, iii) PSA-NCAM (the polysialylated form of the neural cell adhesion molecule), a molecule associated with neuronal migration. Total granule cell number in the dentate gyrus was evaluated by stereological methods, in Nissl-stained sections. Results. Effects of isolation. In P18 isolated animals we found a reduced cell proliferation (-35%) compared to controls and a lower expression of BDNF. Though in absolute terms P45 isolated animals had less surviving cells than controls, they showed no differences in survival rate and phenotype percent distribution compared to controls. Evaluation of the absolute number of surviving cells of each phenotype showed that isolated animals had a reduced number of cells with neuronal phenotype than controls. Looking at the location of the new neurons, we found that while in control animals 76% of them had migrated to the granule cell layer, in isolated animals only 55% of the new neurons had reached this layer. Examination of radial glia cells of P18 and P45 animals by vimentin immunohistochemistry showed that in isolated animals radial glia cells were reduced in density and had less and shorter processes. Granule cell count revealed that isolated animals had less granule cells than controls (-32% at P18 and -42% at P45). Effects of enrichment. In P18 enriched animals there was an increase in cell proliferation (+26%) compared to controls and a higher expression of BDNF. Though in both groups there was a decline in the number of BrdU-positive cells by P45, enriched animals had more surviving cells (+63) and a higher survival rate than controls. No differences were found between control and enriched animals in phenotype percent distribution. Evaluation of the absolute number of cells of each phenotype showed that enriched animals had a larger number of cells of each phenotype than controls. Looking at the location of cells of each phenotype we found that enriched animals had more new neurons in the granule cell layer and more astrocytes and cells with undetermined phenotype in the hilus. Enriched animals had a higher expression of PSA-NCAM in the granule cell layer and hilus Vimentin immunohistochemistry showed that in enriched animals radial glia cells were more numerous and had more processes.. Granule cell count revealed that enriched animals had more granule cells than controls (+37% at P18 and +31% at P45). Discussion. Results show that isolation rearing reduces hippocampal cell proliferation but does not affect cell survival, while enriched rearing increases both cell proliferation and cell survival. Changes in the expression of BDNF are likely to contribute to he effects of environment on precursor cell proliferation. The reduction and increase in final number of granule neurons in isolated and enriched animals, respectively, are attributable to the effects of environment on cell proliferation and survival and not to changes in the differentiation program. As radial glia cells play a pivotal role in neuron guidance to the granule cell layer, the reduced number of radial glia cells in isolated animals and the increased number in enriched animals suggests that the size of radial glia population may change dynamically, in order to match changes in neuron production. The high PSA-NCAM expression in enriched animals may concur to favor the survival of the new neurons by facilitating their migration to the granule cell layer. Conclusions. By using a precocious rodent we could demonstrate that isolated/enriched rearing conditions, at a time window during which intense granule cell proliferation takes place, lead to a notable decrease/increase of total granule cell number. The time-course and magnitude of postnatal granule cell production in guinea pigs are more similar to the human and non-human primate condition than in rats and mice. Translation of current data to humans would imply that exposure of children to environments poor/rich of stimuli may have a notably large impact on dentate neurogenesis and, very likely, on hippocampus dependent memory functions.

Uso de textos musicales (canciones) en la enseñanza del inglés

[ES]El presente artículo de investigación tiene como objetivo principal evaluar cómo el uso de los textos musicales –canciones, como popularmente se conocen– influye en el aprendizaje del inglés como lengua extranjera. Una investigación llevada a cabo con estudiantes de una clase de 2º de ESO nos ha servido para confirmar las hipótesis que en un principio teníamos en lo concerniente a la adquisición de las ocho competencias básicas mediante tareas en las clases de lengua inglesa. Así, el diseño de rúbricas con unos criterios e instrumentos de evaluación específicos nos ha permitido evaluar el grado de adquisición de competencias básicas concretas. [EN]This paper focuses on the impact that the use of music texts –commonly referred to with the term ‘songs’– has on students in teaching English as a foreign language. Through a survey carried out with students of a 2nd year class of Spanish Secondary Education, our initial assumptions in terms of acquisition of key competences in English learning were validated. in acquiring specific key competences by using tasks, rubrics –consisting of detailed assessment criteria and tools– were designed and implemented as the assessment method in order for students to successfully attain specific learning objectives.

Abstrahierendes Lernen durch aktive Modellbildung: Evaluation eines Prozesses und einer Lernumgebung

Die Fähigkeit zum Lernen durch Abstraktion aus Erfahrungen unterscheidet Experten von Novizen. Wir stellen einen Prozess für individuelles abstrahierendes Lernen und eine diesen Prozess unterstützende Lernumgebung vor. Die Ergebnisse einer Pilotstudie zeigen, dass Lernende unter Nutzung der Lernumgebung aus Fallbeispielen ein abstraktes Modell erstellen und über ihren Prozess reflektieren konnten. Dies fiel ihnen leichter, wenn die Fallbeispiele wenige gemeinsame Oberflächenmerkmale aufwiesen. Im Gegensatz zum intendierten Lernprozess wandten manche Lernende einen anderen Prozess an.

Lernzielkatalog für die studentische Lehre im Fachbereich „Geriatrie“ an Fakultäten für Humanmedizin.

Zusammenfassung Die Betreuung geriatrischer Patientinnen und Patienten setzt, nebst einer entsprechenden Haltung, fundierte Kenntnisse in Diagnostik und Behandlung praktisch aller medizinischen Fachgebiete voraus. Daher ist es wichtig, dass die Kompetenz von Studierenden der Humanmedizin im Bereich Geriatrie entsprechend gefördert wird. Bis heute hat jedoch die studentische Ausbildung im Fach Geriatrie an vielen europäischen Universitäten einen unklaren oder untergeordneten Stellenwert. Als ersten Schritt zur Förderung der Lehre in der Geriatrie hat die Europäische Facharztvereinigung Geriatrie (UEMS-GMS) in einem Delphi-Prozess einen Lernzielkatalog entwickelt. Dieser Katalog enthält die Mindestanforderungen mit spezifischen Lernzielen (Wissen, Fertigkeiten und Haltungen), welche die Studierenden der Humanmedizin bezüglich Geriatrie bis zum Abschluss des Medizinstudiums erwerben sollen. Zur Förderung der Implementierung dieses neuen, kompetenzbasierten Lernzielkatalogs an den deutschsprachigen Universitäten wurde eine an den Sprachgebrauch des „DACH-Raums“ (Deutschland, Österreich und Schweiz) angepasste deutsche Version erstellt. Im vorliegenden Beitrag wird diese Übersetzung vorgestellt. Die Fachgesellschaften für Geriatrie aus Deutschland, Österreich und der Schweiz empfehlen den medizinischen Fakultäten der jeweiligen Länder, diesen Katalog umzusetzen.

Mechanisms of heterosynaptic modulation of transmission in Aplysia

Heterosynaptic plasticity has received considerable attention as a means to induce and maintain cell-wide, as opposed to synapse-specific, learning-related modifications. Modulatory neurotransmitters are thought to provide the attentional and motivational state for memory formation. However, the cellular and molecular mechanisms mediating the effects of most of these modulators on synaptic plasticity and learning remain unclear. A well established system for the study of heterosynaptic plasticity is the Aplysia sensorimotor synapse, which is subject regulation by at least two neuromodulators, serotonin (5-HT) and FMRFa. ^ 5-HT engages multiple second messenger cascades to induce short- and long-term facilitation (STF and LTF, respectively) of synaptic transmission. One mechanism proposed to be involved in STF is mobilization of synaptic vesicles from a storage pool to a releasable pool. To investigate this hypothesis, we examined the involvement of the protein synapsin, a central element in the regulation of the storage pool of vesicles in nerve terminals, in STF. 5-HT induced phosphorylation of synapsin and modified its subcellular distribution via PKA and p42/44 MAPK. Electrophysiological experiments and computer simulations suggested that synapsin can support heterosynaptic plasticity by regulating vesicle mobilization. ^ FMRFa induce short- and long-term synaptic depression in Aplysia . Long-term depression (LTD) correlates with morphological changes, the mechanisms of which remain elusive. LTD is also transcription- and translation-dependent, but little is known about the genes expressed and their regulation. We investigated the role of protein degradation via the ubiquitin-proteasome system and the regulation of one of its components, ubiquitin C-terminal hydrolase (ap-uch), in LTD. LTD was sensitive to inhibition of the proteasome and was associated with upregulation of ap-uch mRNA and protein. This upregulation appeared to be mediated by the transcription factor CREB2, which is generally regarded as a transcription repressor. These results suggest that proteasome-mediated protein degradation is engaged in LTD and that CREB2 may act as a transcription activator under certain conditions. ^ These and additional studies on the interaction of the 5-HT and FMRFa-activated pathways suggest that different neuromodulators, by activating several and sometimes overlapping signaling cascades, can exercise bidirectional control on synaptic gain and information processing.^

Aprendizaje del lenguaje escrito : Su evaluación

Este trabajo, que forma parte de una investigación más amplia, está destinado a examinar la disponibilidad y utilización de instrumentos de evaluación del desempeño de alumnos a lo largo del trayecto formativo, respecto del aprendizaje del lenguaje escrito . Surge de la consideración de niveles de rendimiento críticos en el dominio de la lectura y escritura en diferentes niveles educativos, señalados reiteradamente en la literatura especializada del país y del exterior. Con ese propósito se revisan las habilidades y conocimientos implicados a partir de la evidencia empírica surgida de múltiples investigaciones. En el estado actual de la investigación en curso es posible identificar la insuficiencia de disponibilidad y uso de instrumentos de evaluación en nuestro medio. Se desprenden de ello, por un lado, las dificultades para detectar la oportunidad y naturaleza de los problemas que presentan los lectores con dificultades y con trastornos específicos de aprendizaje, y por el otro, la insuficiencia de información sobre indicadores específicos que permitan diseñar las estrategias para optimizar el desempeño en lectura y escritura

Aprendizaje del lenguaje escrito : Su evaluación

Este trabajo, que forma parte de una investigación más amplia, está destinado a examinar la disponibilidad y utilización de instrumentos de evaluación del desempeño de alumnos a lo largo del trayecto formativo, respecto del aprendizaje del lenguaje escrito . Surge de la consideración de niveles de rendimiento críticos en el dominio de la lectura y escritura en diferentes niveles educativos, señalados reiteradamente en la literatura especializada del país y del exterior. Con ese propósito se revisan las habilidades y conocimientos implicados a partir de la evidencia empírica surgida de múltiples investigaciones. En el estado actual de la investigación en curso es posible identificar la insuficiencia de disponibilidad y uso de instrumentos de evaluación en nuestro medio. Se desprenden de ello, por un lado, las dificultades para detectar la oportunidad y naturaleza de los problemas que presentan los lectores con dificultades y con trastornos específicos de aprendizaje, y por el otro, la insuficiencia de información sobre indicadores específicos que permitan diseñar las estrategias para optimizar el desempeño en lectura y escritura

Aprendizaje del lenguaje escrito : Su evaluación

Este trabajo, que forma parte de una investigación más amplia, está destinado a examinar la disponibilidad y utilización de instrumentos de evaluación del desempeño de alumnos a lo largo del trayecto formativo, respecto del aprendizaje del lenguaje escrito . Surge de la consideración de niveles de rendimiento críticos en el dominio de la lectura y escritura en diferentes niveles educativos, señalados reiteradamente en la literatura especializada del país y del exterior. Con ese propósito se revisan las habilidades y conocimientos implicados a partir de la evidencia empírica surgida de múltiples investigaciones. En el estado actual de la investigación en curso es posible identificar la insuficiencia de disponibilidad y uso de instrumentos de evaluación en nuestro medio. Se desprenden de ello, por un lado, las dificultades para detectar la oportunidad y naturaleza de los problemas que presentan los lectores con dificultades y con trastornos específicos de aprendizaje, y por el otro, la insuficiencia de información sobre indicadores específicos que permitan diseñar las estrategias para optimizar el desempeño en lectura y escritura

Efectos de la educación bilingüe España, propuestas de mejora y recursos didácticos relacionados con la metodología AICLE

Desde hace más de una década se vienen realizando en España enormes esfuerzos por implantar programas bilingües español-inglés en los centros educativos y es, por tanto, de gran interés conocer qué efectos ha tenido y está teniendo actualmente la implantación de dichos programas en los alumnos. Son, así pues, objetivos de este trabajo: identificar los efectos de la educación bilingüe en España, establecer propuestas de mejora frente a los problemas o insuficiencias detectadas y, por último, ofrecer una serie de propuestas relativas a la elaboración de materiales didácticos dentro del enfoque metodológico de Aprendizaje Integrado de Contenidos y Lenguas Extranjeras (AICLE). Se presentan también un banco de recursos didácticos de apoyo a uno de los bloques en los que se organiza la asignatura de Tecnología de la Enseñanza Secundaria Obligatoria, los resultados esperados del proyecto, una propuesta de valoración de la puesta en práctica del mismo y, como conclusión, se valoran positivamente este tipo de recursos y se propone la conveniencia de desarrollar nuevos recursos didácticos que aborden otras temáticas dentro de la Tecnología. ABSTRACT From the mid-nineties onwards great efforts have been made in Spain in order to implement bilingual education programs into primary and secondary schools. Therefore, this work’s main objectives are to identify the effects of bilingual education in Spain and to make proposals for the improvement or elimination of the identified problems and weaknesses and for creating Content and Language Integrated Learning- specific learning materials. The work also includes a teacher resource bank to support one of the blocks in which the subject of Technology in Secondary Education is organized, the expected results, an assessment plan to measure the project’s success and, as a conclusion, it is highlighted the need for creating new materials that address other thematic areas within the subject of Tecnology.

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

Ras proteins, key regulators of growth, differentiation, and malignant transformation, recently have been implicated in synaptic function and region-specific learning and memory functions in the brain. Rap proteins, members of the Ras small G protein superfamily, can inhibit Ras signaling through the Ras/Raf-1/mitogen-activated protein (MAP) kinase pathway or, through B-Raf, can activate MAP kinase. Rap and Ras proteins both can be activated through guanine nucleotide exchange factors (GEFs). Many Ras GEFs, but to date only one Rap GEF, have been identified. We now report the cloning of a brain-enriched gene, CalDAG-GEFI, which has substrate specificity for Rap1A, dual binding domains for calcium (Ca2+) and diacylglycerol (DAG), and enriched expression in brain basal ganglia pathways and their axon-terminal regions. Expression of CalDAG-GEFI activates Rap1A and inhibits Ras-dependent activation of the Erk/MAP kinase cascade in 293T cells. Ca2+ ionophore and phorbol ester strongly and additively enhance this Rap1A activation. By contrast, CalDAG-GEFII, a second CalDAG-GEF family member that we cloned and found identical to RasGRP [Ebinu, J. O., Bottorff, D. A., Chan, E. Y. W., Stang, S. L., Dunn, R. J. & Stone, J. C. (1998) Science 280, 1082–1088], exhibits a different brain expression pattern and fails to activate Rap1A, but activates H-Ras, R-Ras, and the Erk/MAP kinase cascade under Ca2+ and DAG modulation. We propose that CalDAG-GEF proteins have a critical neuronal function in determining the relative activation of Ras and Rap1 signaling induced by Ca2+ and DAG mobilization. The expression of CalDAG-GEFI and CalDAG-GEFII in hematopoietic organs suggests that such control may have broad significance in Ras/Rap regulation of normal and malignant states.

Conocimiento tecnológico, pedagógico y disciplinario del profesorado: el caso de un Centro Educativo Inteligente

En este estudio se analiza la integración de las TIC en un escenario de aprendizaje específico: un centro público de Alicante catalogado como Centro Educativo Inteligente [CEI], según el programa de pilotaje homónimo de la Comunidad Valenciana. Se pondera detenidamente, mediante una investigación mixta el conocimiento tecnológico, pedagógico y disciplinar de los docentes a partir del Modelo TPACK. Como instrumentos de evaluación se han utilizado encuestas, entrevistas y grupos de discusión. Entre los resultados alcanzados, destaca la constatación de la inseguridad del profesorado al aplicar los conocimientos tecnológico-pedagógicos en sus clases, si bien se trata de un CEI. Se analiza detenidamente la paradoja establecida entre tal percepción del profesorado y la opinión del equipo directivo, que postula lo contrario.

Effects of two intervention strategies on the behavior of nurses and nurse students related to advance directives

Advance directives are one mechanism for preserving the rights of individuals to exercise some control over their health care when serious illness may prevent them from direct participation. Nurses, as the health care providers with the closest and most sustained contact with critically ill and dying patients, are positioned to assist patients to plan for future health care needs. Although a majority of nurses favor the concept of advance directives for their patients and for themselves, they have not played a significant role in facilitating advance health care planning with their patients nor implemented advance health care planning for themselves.^ Research has also shown that differing forms of education and counseling increase the completion rates for advance directives in selected populations, mostly the elderly and seriously ill. Not yet developed are effective educational strategies to assist nurses and nurse students to make optimal contributions in assisting their clients' plans for future health care decision-making. This study sought to determine whether specific learning strategies (a) increased the involvement of nurses and nurse students in facilitating advance care planning with patients and (b) increased the percentage of the nurses' and nurse students' own personal advance care planning activities.^ The study compared two learning interventions and two populations, nurses and nurse students. The participants were randomly assigned to one of the two learning interventions, L1 or L2. Participants in L1 received a lecture, discussion and exploration of the forces impacting on advance directive behavior. Participants in L2 received the same intervention components with the additional component of group practice completing advance directives.^ Analysis of the data by chi-square and logistic regression did not support the hypotheses that the practice component would make a difference in the participants' facilitation of advance care planning with patients or in their own personal advance care planning activities. There were significant differences in post-intervention behavior between the nurse and nurse student groups. The nurses in the study did significantly more facilitation of advance care planning with patients and completed significantly more advance care documents than the nurse students post-intervention. However, the nurse students held more post-intervention family discussions than did the nurses. ^

Class placement and academic and behavioral variables as predictors of graduation for students with disabilities

Dropout rates impacting students with high-incidence disabilities in American schools remain staggering (Bost, 2006; Hehir, 2005). Of this group, students with Emotional Behavioral Disorders (EBD) are at greatest risk. Despite the mandated national propagation of inclusion, students with EBD remain the least included and the least successful when included (Bost). Accordingly, this study investigated the potential significance of inclusive settings and other school-related variables within the context of promoting the graduation potential of students with Specific Learning Disabilities (SLD) or EBD. This mixed-methods study investigated specified school-related variables as likely dropout predictors, as well as the existence of first-order interactions among some of the variables. In addition, it portrayed the perspectives of students with SLD or EBD on the school-related variables that promote graduation. Accordingly, the sample was limited to students with SLD or EBD who had graduated or were close to graduation. For the quantitative component the numerical data were analyzed using linear and logistic regressions. For the qualitative component guided student interviews were conducted. Both strands were subsequently analyzed using Ridenour and Newman’s (2008) model where the quantitative hypotheses are tested and are later built-upon by the related qualitative meta-themes. Results indicated that a successful academic history, or obtaining passing grades was the only significant predictor of graduation potential when statistically controlling all the other variables. While at a marginal significance, results also yielded that students with SLD or EBD in inclusive settings experienced better academic results and behavioral outcomes than those in self-contained settings. Specifically, students with SLD or EBD in inclusive settings were found to be more likely to obtain passing grades and less likely to be suspended from school. Generally, the meta-themes yielded during the student interviews corroborated these findings as well as provided extensive insights on how students with disabilities view school within the context of promoting graduation. Based on the results yielded, provided the necessary academic accommodations and adaptations are in place, along with an effective behavioral program, inclusive settings can be utilized as drop-out prevention tools in special education.