Desenvolvimento econômico e condições de vida: a força de uma ideia e uma ideia força na obra de Roberto Simonsen

The intent of this article is to investigate the contribution of Roberto Simonsen for the knowledge and the improvement of living conditions of workers in Brazil. Our hypothesis is that the intellectual contributed in a fundamental way to the theme of the living conditions of workers, especially workermen, was inserted into a broader agenda, that of “national-developmentalism”, to which it also contributed signifi cantly, as we will discuss throughout this work, being the subject at the center his theories, the core, the foundation of which he went to build the corollary of ideas about Brazil and the world that consecrated him as a great thinker in Brazil.

A contribuição de Roberto Simonsen para a institucionalização da sociologia aplicada no Brasil

The aim of this study is to investigate the importance of Roberto Simonsen and research on the living conditions of workers in São Paulo by the Free School of Sociology and Social Policy in the 1930s to the consolidation of sociology applied to Brazil. We propose to investigate the influence of Roberto Simonsen on using the model of Sociology in the cited research, the intellectual influences which justify the choice of both researchers, the methodology and the practical consequences of these attitudes for sociology and for Brazil.

Uma resenha, mesmo que tardia: Roberto Pontual e a sobrevida da questão da identidade nacional na arte brasileira dos anos 1980

Partindo do panorama traçado pelo crítico carioca Roberto Pontual em Explode Geração!, livro publicado em 1985, pretende-se analisar em que medida a questão da identidade brasileira na arte realizada no país encontrou respaldo na cena dos anos 1980, momento em que a produção de uma jovem geração de artistas foi alinhada à tradição do barroco brasileiro, tradição esta que, segundo o crítico, perpassaria e alinhavaria alguns dos trabalhos do período, fornecendo-lhes uma espécie de chancela de uma brasilidade insuspeita, a despeito de todo contato que travavam com a arte internacional. Esta "resenha tardia" propõe-se tão somente indicar caminhos possíveis para futuros estudos mais detalhados acerca de tal questão.

Antiparasitical chemotherapy in Chagas' disease cardiomyopathy: current evidence

Chronic chagasic cardiomyopathy affects 20% of Chagas disease patients. At present, Chagas disease chemotherapy uses nitrofurans, benznidazole (Rochagan (R), Rodanil (R), Roche) or nifurtimox (Lampit (R), Bayer). Treatment during acute and recent chronic phases in childhood effects 71.5% and 57.6%, respectively, of parasitological cure. However, in clinical trials during the late chronic phase, only 5.9% of parasitological cure were achieved. This review focuses on the benefit from aetiological treatment to avoid, stop or revert myocarditis. Divergent data gathered from clinical practice are not convincing to support prescription of aetiological treatment as routine for indeterminate and cardiac chronic patients.

Deficient Regulatory T Cell Activity and Low Frequency of IL-17-Producing T Cells Correlate with the Extent of Cardiomyopathy in Human Chagas' Disease

Background: Myocardium damage during Chagas' disease results from the immunological imbalance between pro-and production of anti-inflammatory cytokines and has been explained based on the Th1-Th2 dichotomy and regulatory T cell activity. Recently, we demonstrated that IL-17 produced during experimental T. cruzi infection regulates Th1 cells differentiation and parasite induced myocarditis. Here, we investigated the role of IL-17 and regulatory T cell during human Chagas' disease. Methodology/Principal Findings: First, we observed CD4(+)IL-17(+) T cells in culture of peripheral blood mononuclear cells (PBMC) from Chagas' disease patients and we evaluated Th1, Th2, Th17 cytokine profile production in the PBMC cells from Chagas' disease patients (cardiomyopathy-free, and with mild, moderate or severe cardiomyopathy) cultured with T. cruzi antigen. Cultures of PBMC from patients with moderate and severe cardiomyopathy produced high levels of TNF-alpha, IFN-gamma and low levels of IL-10, when compared to mild cardiomyopathy or cardiomyopathy-free patients. Flow cytometry analysis showed higher CD4(+)IL-17(+) cells in PBMC cultured from patients without or with mild cardiomyopathy, in comparison to patients with moderate or severe cardiomyopathy. We then analyzed the presence and function of regulatory T cells in all patients. All groups of Chagas' disease patients presented the same frequency of CD4(+)CD25(+) regulatory T cells. However, CD4(+)CD25(+) T cells from patients with mild cardiomyopathy or cardiomyopathy-free showed higher suppressive activity than those with moderate and severe cardiomyopathy. IFN-gamma levels during chronic Chagas' disease are inversely correlated to the LVEF (P = 0.007, r = -0.614), while regulatory T cell activity is directly correlated with LVEF (P = 0.022, r = 0.500). Conclusion/Significance: These results indicate that reduced production of the cytokines IL-10 and IL-17 in association with high levels of IFN-gamma and TNF-alpha is correlated with the severity of the Chagas' disease cardiomyopathy, and the immunological imbalance observed may be causally related with deficient suppressor activity of regulatory T cells that controls myocardial inflammation.

Management of diabetes mellitus and associated cardiovascular risk factors in Brazil – the Brazilian study on the practice of diabetes care

Abstract Background The Brazilian Study on the Practice of Diabetes Care main objective was to provide an epidemiological profile of individuals with type 1 and 2 diabetes mellitus (DM) in Brazil, concerning therapy and adherence to international guidelines in the medical practice. Methods This observational, cross-sectional, multicenter study collected and analyzed data from individuals with type 1 and 2 DM attending public or private clinics in Brazil. Each investigator included the first 10 patients with type 2 DM who visited his/her office, and the first 5 patients with type 1 DM. Results A total of 1,358 patients were analyzed; 375 (27.6%) had type 1 and 983 (72.4%) had type 2 DM. Most individuals were women, Caucasian, and private health care users. High prevalence rates of hypertension, dyslipidemia and central obesity were observed, particularly in type 2 DM. Only 7.3% and 5.1% of the individuals with types 1 and 2 DM, respectively, had optimal control of blood pressure, plasma glucose and lipids. The absence of hypertension and female sex were associated with better control of type 1 DM and other cardiovascular risk factors. In type 2 DM, older age was also associated with better control. Conclusions Female sex, older age, and absence of hypertension were associated with better metabolic control. An optimal control of plasma glucose and other cardiovascular risk factors are obtained only in a minority of individuals with diabetes. Local numbers, compared to those from other countries are worse.

Roberto Carlos e a identidade brasileira na canção

Roberto Carlos é, ao mesmo tempo, o mais popular e o mais rejeitado dos artistas brasileiros. Nosso artigo pretende compreender as raízes dessa contradição, compreendendo tanto a positividade e o valor de sua obra - buscando relativizar uma série de estigmas e preconceitos que rondam sua figura, demonstrando, por assim dizer, a legitimidade de sua coroa - quanto o lugar a partir de onde falam seus antagonistas, de modo a perceber o conjunto de interesses e posições envolvidas nesses juízos críticos.

esempio di tavola 1: rilievo a vista di un oggetto e proiezioni ortogonali. designer: Roberto Paoli, Milano

esempio della prima esercitazione in aula

Estética y (micro)política en la narrativa de Roberto Echavarren

Doctorado en Literatura y Teoría de la Literatura

Le parole incrociate. Lucio Dalla e Roberto Roversi: Nascita di un cantautore (1973-1976)

La produzione Dalla-Roversi si iscrive nella cornice storica degli anni’70, quelli che nell'immaginario comune vengono chiamato “anni piombo”. In realtà gli anni ’70, in particolare il Settantasette bolognese, sono molto altro: sono anni di fervore culturale e di sperimentazione del linguaggio, grazie anche alla nascita delle radio libere. La collaborazione tra i due artisti dura tre anni, dal 1973 al 1976, e porterà alla pubblicazione di tre album: Il giorno aveva cinque teste, Anidride solforosa e Automobili. I tre dischi cambieranno la vita di Lucio Dalla, sia dal punto di vista professionale che personale. Nel 1977, infatti, dopo la “rottura” con Roversi, Dalla pubblicherà il suo capolavoro: Come è profondo il mare, primo album scritto e musicato interamente dal cantautore. A questo punto della sua carriera può essere definito tale, in quanto dimostra di essere capace di scrivere testi che possono essere considerati e poetici e di musicarli in maniera consapevole.