586 resultados para Pier Bottoni


Relevância:

10.00% 10.00%

Publicador:

Relevância:

10.00% 10.00%

Publicador:

Resumo:

A presente dissertação é fruto da pesquisa de mestrado realizada sobre o poema Ode marítima, de Álvaro de Campos, heterônimo do poeta português Fernando Pessoa. O poema foi estudado à luz de considerações teóricas que pudessem sustentar o teor artístico do citado poema, para além de um posicionamento estritamente analítico. Em outras palavras, as contribuições teóricas de Walter Benjamin, Philippe Lacoue-Labarthe, Theodor W. Adorno, entre outros, visa propocionar um discurso de pesquisa que seja poético, respeitando a manifestação literária em questão o poema. Nesse sentido, Ode marítima apresentou, ao longo da pesquisa, diferentes temas. Tais temas foram estudados, com o embasamento teórico referido, separadamente. São eles: Imaginação, Cais Absoluto, Sonho, Força e Infância. Para cada tema, um capítulo foi elaborado. Todos os temas pesquisados confluem para a apreensão da poética de Álvaro de Campos uma vez que Ode marítima é um poema singular e fundamental da obra poética do citado heterônimo. Desse modo, a pesquisa realizada não se limita à abordagem do citado poema, mas alcança demais poemas de Álvaro de Campos, de modo que se torna possível conjeturar acerca da poesia deste heterônimo. Partindo, portanto, de um poema, a pesquisa pretende poder dimensionar a obra de Álvaro de Campos, pontuando suas particularidades trazidas pela Ode marítima, mas tendo ciência de que trata-se de uma proposta entre tantas outras válidas e enriquecedoras.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

This is the Kent estuary survey 18th July 1981 produced by the North West Water Authority in 1981. The report focuses on a tidal cycle survey carried out on the Kent estuary on the 18th August, 1981. The chemical water quality at Arnside Pier and at New Barns was, on the whole, acceptable. However, samples taken downstream of the outfall at low water for total coliforms and E. coli were all above the EEC mandatory level whilst those for faecal streptococci were all above the guideline value. This document shows chemical and bacteriological data analysed at Kent estuary such chloride, dissolved oxygen, BOD, ammonia, nitrate, phosphate, total coliforms, E. coli and Faecal streptococci.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

In the present investigation of thin aerofoil wakes we compare the global nonlinear dynamics, obtained by direct numerical simulations, to the associated local instability features, derived from linear stability analyses. A given configuration depends on two control parameters: the Reynolds number Re and the adverse pressure gradient m (with m < 0) prevailing at the aerofoil trailing edge. Global instability is found to occur for large enough Re and |m|; the naturally selected frequency is determined by the local absolute frequency prevailing at the trailing edge. © 2010 Springer Science+Business Media B.V.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

The vibration behavior of piled foundations is an important consideration in fields such as earthquake engineering, construction, machine-foundation design, offshore structures, nuclear energy, and road and rail development. This paper presents a review of the past 40 years' literature on modeling the frequency-dependent behavior of pile foundations. Beginning with the earliest model of a single pile, adapted from those for embedded footings, it charts the development of the four pile-modeling techniques: the "dynamic Winkler-foundation" approach that uses springs to represent the effect of the soil; elasticcontinuum-type formulations involving the analytical solutions for displacements due to a subsurface disk, cylinder, or other element; boundary element methods; and dynamic finite-element formulations with special nonreflecting boundaries. The modeling of pile groups involves accounting for pile-soil-pile interactions, and four such methods exist: interaction factors; complete pile models; the equivalent pier method; and periodic structure theory. Approaches for validating pile models are also explored. Copyright © 2013 by ASME.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Significant progress has been made towards understanding the global stability of slowly-developing shear flows. The WKBJ theory developed by Patrick Huerre and his co-authors has proved absolutely central, with the result that both the linear and the nonlinear stability of a wide range of flows can now be understood in terms of their local absolute/convective instability properties. In many situations, the local absolute frequency possesses a single dominant saddle point in complex X-space (where X is the slow streamwise coordinate of the base flow), which then acts as a single wavemaker driving the entire global linear dynamics. In this paper we consider the more complicated case in which multiple saddles may act as the wavemaker for different values of some control parameter. We derive a frequency selection criterion in the general case, which is then validated against numerical results for the linearized third-order Ginzburg-Landau equation (which possesses two saddle points). We believe that this theory may be relevant to a number of flows, including the boundary layer on a rotating disk and the eccentric Taylor-Couette-Poiseuille flow. © 2014 Elsevier Masson SAS. All rights reserved.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Expansion of economic activities, urbanisation, increased resource use and population growth are continuously increasing the vulnerability of the coastal zone. This vulnerability is now further raised by the threat of climate change and accelerated sea level rise. The potentially severe impacts force policy-makers to also consider long-term planning for climate change and sea level rise. For reasons of efficiency and effectiveness this long-term planning should be integrated with existing short-term plans, thus creating an Integrated Coastal Zone Management programme. As a starting point for coastal zone management, the assessment of a country's or region's vulnerability to accelerated sea level rise is of utmost importance. The Intergovernmental Panel on Climate Change has developed a common methodology for this purpose. Studies carried out according to this Common Methodology have been compared and combined, from which general conclusions on local, regional and global vulnerability have been drawn, the latter in the form of a Global Vulnerability Assessment. In order to address the challenge of coping with climate change and accelerated sea level rise, it is essential to foresee the possible impacts, and to take precautionary action. Because of the long lead times needed for creating the required technical and institutional infrastructures, such action should be taken in the short term. Furthermore, it should be part of a broader coastal zone management and planning context. This will require a holistic view, shared by the different institutional levels that exist, along which different needs and interests should be balanced.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

本文主要利用ECOMSED模式对长江口及邻近海域的水文、泥沙过程进行三维数值模拟,并结合实测资料分析其水动力、泥沙输运、底床冲淤等特征;然后利用欧拉二相流模型模拟小尺度条件下长江口底床上圆桩周围的水流和泥沙冲刷、输运规律。 通过资料分析和ECOMSED数值模拟结果比较,我们得出:长江口口门内为非正规半日潮流区,潮流运动形式多为往复流,落潮流占优。落潮流速大于涨潮流速,流速垂向分布从表层到底层递减。悬沙浓度与流速关系密切,一般来说,流速越大,悬沙浓度越高;一个潮周期过程中会出现两次、三次或四次泥沙再悬浮,分别是涨急、落急、涨转落、落转涨时刻;盐水楔结构对粘性与非粘性悬沙浓度的分布起决定性作用,转流时泥沙再悬浮主要是由于这时会出现盐水楔,并形成垂向环流,使床面大量未被固结的泥沙再悬浮,形成峰值。悬浮泥沙垂向分布可分为垂线型,斜线型,抛物线型和L型。流场和底床冲淤变化与水深关系密切:深水区,流速较大,底床冲淤变化也较大。其中,受径流影响区表现为淤积,受潮流影响区表现为冲刷;浅水区基本表现为淤积。 从模式运行结果和实测资料比较可以看出,该模型可以较好的模拟长江口水流、悬浮泥沙分布与变化;能够再现在径流入海口处,盐水楔结构及其诱生的垂向环流从形成到发展,又到消失的完整过程;也能够展示底床的冲淤变化。对于我们模拟长江口背景流场,了解该区域内水动力变化、悬浮泥沙输运、底床冲淤等有重要意义。 在欧拉二相流模型对长江口底床上圆桩周围的水流和局部冲刷数值模拟过程中,我们不仅考虑水流和泥沙之间的作用,还引入泥沙颗粒之间的相互影响。模拟结果较合理的展示了圆桩周围的流场类型和底床冲刷变化:在圆桩前方,流速减小并形成垂向涡旋,从而产生局部冲刷;在圆桩两侧,水流加速,挟带上游泥沙向下输送,并在内侧堆积;而在圆桩后面,存在流速分离区。在该分离区内流速很小,并且当流速较大时,会产生回流,形成两个对称的漩涡。流速越大,圆桩前由垂向涡旋引起的局部冲刷就越明显;而当底床泥沙粒径变小时,泥沙临界起动流速变小,底床也更容易被冲刷。悬浮泥沙浓度分布受流场的影响,并且当粒径小而流速大时,能悬浮到更高的深度。

Relevância:

10.00% 10.00%

Publicador:

Resumo:

A series of simulation experiments on carbon steel (A(3) steel) and low alloy steel (16 Mn steel) in marine atmosphere (MA), seawater (SW) and seabed sediment (SBS) including rough sea sand, fine sea sand and seabed mud were carried out indoors for a year or so by means of individually hanging plates (IHP) and electrically connected hanging plates (ECHP). The corrosion of steels in SBS was mainly due to the macrogalvanic cell effect. The steel plates at the bottom of SBS, as the anode of a macrogalvanic cell, showed the heaviest corrosion with a corrosion rate of up to 0.12 mm/a, approximately equal to that of steel plates in marine atmosphere. The test results showed that the corrosion rates of A(3) and 16 Mn steel in marine environment were in the order: MA > SW > SBS by the IHP method; and MA > SBS > SW by the ECHP method. The corrosion rates of steels in the water/sediment interface were directly proportional to the grain size of the SBS by the ECHP method, but those of steels in the water/sediment interface did not vary with the grain size of SBS by the IHP method. The corrosion rate of low-alloy steel was a little higher than that of carbon steel. The results of this study have important applications for design of offshore steel structures such as oil platform, pier, and port.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

The anchorages are unparalleled structures only in a suspension bridge, and as main bearing facilities, play an important role in connecting the superstructures and the ground. The tunnel anchorage, as one alternative type of the anchorages, has more advantages over its counterpart, the gravity anchorage. With the tunnel anchorages adopted, not only can surface excavation be reduced to protect the environment, and natural condition of the rock be utilized and potential bearing capacity of surrounding rock be mobilized to save engineering cost, but also the technological predominance of auxiliary engineering measures, such as prestressed concrete, anchoring piles, rock anchors and collar beam between the two separated anchorages, can be easily cooperated to work together harmoniously under the circumstances of poor rock quality. There are plentiful high mountains and deep canyons in west part of China, and long-span bridge construction is inevitably encountered in order to realize leapfrogging development of the transportation infrastructure. Western mountainous areas usually possess the conditions for constructing tunnel anchorages, and therefore, the tunnel anchorages, which are conformed to the conception of resource conservative and sustainable society, extremely have application and popularization value in western underdeveloped region. The scientific and technological problem about the design, construction and operation of tunnel anchorages should be further investigated. Combining the engineering of western tunnel anchorages for the Balinghe Suspension Bridge, this paper probed into the survey method and in-situ test method for tunnel anchorages, scientific rock quality evaluation of surrounding rock to provide reasonable physical and mechanical parameters for design, construction and operation of tunnel anchorages, bearing capacity estimation for tunnel anchorage, deformation prediction of the anchorage-rockmass system, tunnel-anchorage slope stability analysis and the evaluation of excavation stability and degree of safety of the anchorage tunnel. The following outcomes were obtained: 1. Materials of tunnel anchorages of suspension bridge built (and in progress) at home and abroad were systematically sorted out, with the engineering geological condition and geomechanical property of surrounding rock around the anchorage tunnel, the design size of anchorages and the construction method of anchorage tunnel paid more emphasis on, to unveil the internal relationship between the engineering geological conditions of surrounding rock and the design size and axis angle of anchorages and provide references for future design, construction and study of tunnel anchorages. 2. Physical and mechanical parameters were recommended based on three domestic and foreign methods of rock quality evaluation. 3. In-situ tests, adopting the back-thrust method, of two kinds of reduced scale model, 1/30 and 1/20, for the tunnel anchorages were conducted in the declining exploration drift with rock mass at the test depth being the same as surrounding rock around real anchorages, and reliable field rockmass displacement data were acquired. Attenuation relation between the increment of distance from the anchorage and the decrement of rockmass displacement under maximum test load, and influential scope suffered by anchorage load were obtained. 4. Using similarity theory, the magnitude of real anchorage and rockmass displacement under design load and degree of safety of the anchorage system were deduced. Furthermore, inversion analysis to deformation modulus of slightly weathered dolomite rock, the surrounding rock of anchorage tunnel, was performed by the means of numerical simulation. 5. The influential law of the geometrical size to the limit bearing capacity of tunnel anchorage was studied. 6. Based on engineering geological survey data, accounting for the combination of strata layer and adverse discontinuities, the failure patterns of tunnel anchorage slope were divided into three modes: sliding of splay saddle pier slope, superficial-layer slippage, and deep-layer slippage. Using virtual work principle and taking anchorage load in account, the stability of the three kinds of failure patterns were analyzed in detail. 7. The step-by-step excavation of anchorage tunnel, the numerical overload and the staged decrement of rock strength parameters were numerically simulated to evaluate the excavation stability of surrounding rock around anchorage tunnel, the overload performance of tunnel anchorage, and the safety margin of strength parameters of the surrounding rock.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

In order to realize fast development of the national economy in a healthy way and coordinate progress with whole society, the country has implemented the strategy of development of the western region. An important action of finishing this strategic task is to accelerate the highway construction in the western region, join the western region and places along the coast, the river, the border with goods and materials, technology, and personnel interchanges, and then drive development of the local economy.The western region was influenced by the Himalaya Tectonization in Cenozoic, and the crust rose and became the plateau. In the course of rising, rivers cut down sharply to form a lot of high mountains and gorges.Because of topography and geomorphology, bridges in the traffic construction in the alpine gorge area are needed. Rivers have characteristics of large flow, fast velocity and high and steep river valley, so building a pier in the river is not only very difficult, but also making the cost increase. At the same time, the impact that the pier is corroded and the bridge base that is drawn to be empty by flow are apt to cause destruction of the pier. For those reasons, suspending bridge and cable-stay bridge are usually adopted with the single and large span. For the large span bridge, the pier foundation could receive ten thousand and more vertical strength, bending moment and near kiloton horizontal thrust.Because bank slope in the alpine gorge district is cut deeply and unsettled big, natural stability is worse under endogenic and exogenic force. When bank slope bears heavy vertical strength, bending moment and horizontal thrust facing the river, it will inevitably make the balance state of rock and soil mass change, bridge bank slope deform, and even destroyed. So the key problem at the time of the large span's bridge construction in the alpine gorge area is how to make it stable.So based on the spot investigation, the Engineering Geology Analysis Method is very important to grasp the bank slope stability. It can provide the bank slope stability macroscopic ally and qualitatively, and reference to the indoor calculation. The Engineering Geology Analysis Method is that by way of analyzing and investigating terms of bank slope instability, stability development trend, the ancient rock slide and devolution in the site, stability comprehensive evaluation primarily, current and future stability of bank slope is gotten, realizing the intention to serving the concrete engineering.After the Engineering Geology Analysis Method is applied to project instances of BeiPan River Bridge and BaLin River Bridge, results are accord with bank slope actual conditions, which proves sites are suited to building bridges from site stability.we often meet bank slope stability issues in the traffic construction in the alpine gorge areao Before the evaluation of the bank slope stability, the engineering geological condition is investigated first. After that, the next exploration target and geology measures are decided. So, the Engineering Geology Analysis Method that the investigation of the engineering geological condition is the main content is quite important in practice. The other evaluations of the bank slope stability are based on it. Because foundation receives very heavy load, for the big span's bridge in the alpine gorge area, a long pile of the large diameter (D^0.8m) is usually selected. In order to reflect rock mass's deformation properties under rock-socketed pile function, the author has used the FLAG30 software for rock and soil mass and done many numerical simulations. By them, the author launches the further investigation on deformation properties of bank slope under different slope angle, pile length, diameter, elastic modulus, load, bank slope's structure, etc. Some conclusion meaningful to the design and produce are obtained.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Introduction: Parkinson‟s disease (PD) is characterized by a chronic progressive loss of nigrostriatal dopaminergic neurons that is associated with chronic neuroinflammation. Current treatments for PD can significantly improve symptoms but do not cure the disease or slow its progression. An approach used in existing therapies is based on the inhibition of monoamine oxidase (MAO), enzyme involved in the metabolic degradation of dopamine. Although, preclinical studies showed that MAO-B inhibitors have neuroprotective activity in cellular and animal models of PD, clinical trials did not completely confirm this result. Therefore a large number of new molecules, with more potent MAO-B inhibitory activity and a possible neuroprotective effect, have been proposed to replace the pre-existing MAO-B inhibitors. The profile of the recent MAO inhibitor, SZV558, appears to be particularly interesting because of its pharmacodynamic, favorable for disease-modifying properties and its irreversible MAO-B enzyme bind. The enhancement of adult neurogenesis could be of great clinical interest in the management of neurodegenerative disorders. In line with this, the metformin, a well-known antidiabetic drug, has recently been proposed to promote neurogenesis and to have a neuroprotective effect on the neurodegenerative processes induced by the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in a mice PD model. Although, PD has multiple origins, one hypothesis is that amphetamine-related drugs may be part of the wide array of factors leading to the dopaminergic neuron degeneration that causes the disease. These hypothesis are supported by different results that showed a persistent, long-term dopaminergic toxicity induced by 3,4-methylenedioxymethamphetamine (MDMA) in mice. Moreover, the MDMA, altering the dopaminergic transmission, may affect neurogenesis and synaptogenesis. On these basis, considering that the young brain is particularly sensitive to drug-induced neurotoxicity, the consumption of MDMA during the adolescence might increase the vulnerability of dopaminergic neurons. However, the use of amphetamine-related drugs by adolescent and young people is often combined with caffeinated energy drinks in order to amplify their stimulant actions. Although caffeine use is safe, the combined treatment of caffeine and MDMA increases not only the DA release but also the microglia and astroglia activation. Aims: During my Ph.D. I studied the influence of neuroprotective drugs, such as MAO inhibitors and metformin, or substances, such as caffeine, on the neurodegenerative effects of two dopaminergic toxins, MDMA and MPTP, in mice. 1. In the first phase of my study, I evaluated the neuroprotective activity of the new MAO-B inhibitor SZV558, compared with well-known rasagiline, in a chronic mouse model of MPTP plus probenecid (MPTPp), which induces a progressive loss of nigrostriatal dopaminergic neurons. 2. Previous results showed that when MDMA is associated with caffeine, a more pronounced degeneration in adolescent compared with adult mice was observed. To better clarify the molecular mechanism at the base of the different neurotoxic effect of this drug association at different ages, I evaluated the neuronal nitric oxide synthase (nNOS) expression, which plays a critical role in the integration of dopaminergic and glutamatergic transmissions, in the CPu of adolescent or adult mice treated with MDMA, alone or in combination with caffeine. 3. Finally, I investigated the neuroprotective effect of metformin against dopaminergic neurotoxicity induced by MDMA in the CPu and SNc of adult mice. Conclusions: These results demonstrated that the dopaminergic neurodegenerative process may be induced or conditioned by environment stressors or substances which influence, through different ways, the development of neurodegenerative mechanisms. In the present study I evaluated the effects of 3 substances, known as potentially neuroprotective, in combination with two different neurotoxins that affect the nigrostriatal dopaminergic system. The SZV558 MAO-B inhibitor and the metformin protected the nigrostriatal pathway, usually affected in PD, by MPTP- and MDMA- induced neurotoxicity, respectively. On the other hand, caffeine, administrated with MDMA, showed a neurotoxic potential depending on the age of consumers, confirming the vulnerability of adolescent brain to consumption of drug and substances that affected the dopaminergic system. In conclusion, the study of neurodegenerative processes may be relevant to understand the human pharmacology, the origin and development of neurodegenerative disease and to predict the neurotoxic effect of drug abuse.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Wydział Chemii: Pracownia Spektrochemii Organicznej

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Historical Annapolis Foundation (HAF) conducted terrestrial archaeological investigations at site 18AP21 in the city of Annapolis, Maryland. Excavations were carried out at this National Register site ostensibly as a Phase II project to evaluate the site and assess the need for further work. The site is at 99 Main Street in the center of downtown Annapolis, near the Annapolis waterfront. The project was carried out as part of the advanced work for the Annapolis History Center project, to be built in the adjoining buildings of 99 Main and 196 Green Streets. The buildings are the property of the Historic Annapolis Foundation and located in Maryland Research Unit 7. The excavations were undertaken by HAF, and funded by HAFF. The work was conducted for HAF and MHT, who holds an archaeological easement on the property. This preliminary phase of work included stratigraphic excavation of two testpit units. These two units revealed that the site of the existing 99 Main Street building was the location of three previous constructions. The current building at 99 Main Street, built in 1791, was preceded by an earlier brick dwelling, evidenced by a stout pier of bricks, which was attached to a wooden-sided structure that stood on a foundation of brick and stone. Ceramics indicate that these buildings date to the early-middle of the 18th century. A third structure of post-in-ground construction, evidenced by recovery of burned posts and wood fragments, likely existed prior to these, but evidence was scant. These excavations reveal that the site of 18AP21 holds potential for understanding Annapolis's early cultural developments, especially in the area of initial settlement and the origins of waterfront commerce. The assemblage of artifacts recovered includes a broad sample of common 18th century pottery such as creamware and Chinese export porcelain, and also includes some early colonial types such as tin-glazed earthenware and various red-bodied slipwares. The excavations do not provide conclusive evidence of the construction sequence. Consultation with MHT representatives indicates that further work at the site will likely be needed before modifications to the floor of the building can progress.