Function and Regulation of Cytochrome P450 4V2 and the Implications in Bietti’s Crystalline Dystrophy

Thesis (Ph.D.)--University of Washington, 2016-06

Perguntou o juiz ao tutor pela pessoa deste órfão: os magistrados na ordem sócio educacional do Seridó (século XIX)

This work has the objective to analyze the presence of justice, embodied in the orphans of judges, the encouragement, guidance and custody of minor heirs of the Village of Currais Novos, the area called Seridó of Rio Grande do Norte, especially with regard to education in the century XIX. Aims the meaning of the performance of judges in education and their practices, whereas this figure had a power that went beyond its mere function, but played a political role, taking responsibility for guarding and protection of property left by families of the Imperial period. The study focuses on the set of notary offices documents, inventories, sharing, self accounts and orders, belonging to the District of Currais Novos Forum in the period between the years 1822 to 1829. Finally, the conclusion demonstrates how Judges controlled the education of orphans, through tutors, and it is used for this purpose, the account acts as a procedural mechanism and documentary of its judicial activity.

Health Knowledge, Attitudes, and Practices among Street Children in LMICs

Background: Worldwide, it is estimated that there are up to 150 million street children. Street children are an understudied, vulnerable population. While many studies have characterized street children’s physical health, few have addressed the circumstances and barriers to their utilization of health services.

Methods: A systematic literature review was conducted to understand the barriers and facilitators that street children face when accessing healthcare in low and middle income countries. Six databases were used to search for peer review literature and one database and Google Search engine were used to find grey literature (theses, dissertations, reports, etc.). There were no exclusions based on study design. Studies were eligible for inclusion if the study population included street children, the study location was a low and middle income country defined by the World Bank, AND whose subject pertained to healthcare.

In addition, a cross-sectional study was conducted between May 2015 and August 2015 with the goal of understanding knowledge, attitudes, and health seeking practices of street children residing in Battambang, Cambodia. Time location and purposive sampling were used to recruit community (control) and street children. Both boys and girls between the ages of 10 and 18 were recruited. Data was collected through a verbally administered survey. The knowledge, attitudes and health seeking practices of community and street children were compared to determine potential differences in healthcare utilization.

Results: Of the 2933 abstracts screened for inclusion in the systematic literature review, eleven articles met all the inclusion criteria and were found to be relevant. Cost and perceived stigma appeared to be the largest barriers street children faced when attempting to seek care. Street children preferred to receive care from a hospital. However, negative experiences and mistreatment by health providers deterred children from going there. Instead, street children would often self treat and/or purchase medicine from a pharmacy or drug vendor. Family and peer support were found to be important for facilitating treatment.

The survey found similar results to the systematic review. Forty one community and thirty four street children were included in the analysis. Both community and street children reported the hospital as their top choice for care. When asked if someone went with them to seek care, both community and street children reported that family members, usually mothers, accompanied them. Community and street children both reported perceived stigma. All children had good knowledge of preventative care.

Conclusions: While most current services lack the proper accommodations for street children, there is a great potential to adapt them to better address street children’s needs. Street children need health services that are sensitive to their situation. Subsidies in health service costs or provision of credit may be ways to reduce constraints street children face when deciding to seek healthcare. Health worker education and interventions to reduce stigma are needed to create a positive environment in which street children are admitted and treated for health concerns.

Quantifying Selection Bias from Birth History Estimates of Child Mortality

Thesis (Master's)--University of Washington, 2016-08

Under The Dual System: Children Of Rural-Hukou Migrants In China

Thesis (Ph.D.)--University of Washington, 2016-06

L'insaisissable catégorie sociale d'enfants orphelins d'Afrique: de quoi parle-t-on?

There is no definition of orphans that would allow to know without confusion who is an orphan child. This article analyses the challenges and difficulties in defining and targeting the social category of orphans. It is based on a number of works, as well as the field research on the social actor's logics regarding the family support to orphans among the Mossi people in Ouagadougou (Burkina Faso), for my Ph.D. in sociology at Laval University (Canada). In fact, international charity organisations use orphans as a vulnerable and universal category. This has been done through the propagation of information on HIV. From the social sciences perspective, the category of orphans covers a variety of realities, and making the choice to see it otherwise would hide the diversity of those realities.

Empire's Children: Soviet Childhood in the Age of Revolution

Ideas of childhood and citizenship stood at the center of the Soviet Union’s empire-building project during the 1920s and 1930s. After the 1917 Revolution the Bolsheviks were faced with the challenge of establishing a new state structure and governing a vast territory inherited from its tsarist predecessor. In the early years of the Soviet project, new leaders enlisted a cadre of professionals tasked with not only creating the norms of childhood and the everyday, but also implementing policies to modernize habits and values of the empire’s younger citizens. To understand how children became a prime focus of Soviet imperial and ethno-cultural politics, my dissertation employs discourse analysis and compares the ways in which Soviet imperial policies were implemented in two ethnically different regions: the Buddhist Republic of Kalmykia as the colonial case study and Moscow as the Metropole. The current project examines newspapers, treatises, and inspectors’ reports over the span of twenty years. It finds that the Bolsheviks’ initial values and discourses in the realm of children’s education, health, leisure and nutrition, all which were scientifically designed to transform children into ideal Soviet and modern citizens, changed over time as a result of the competing ideologies among local elites and the challenges they faced while intervening in children’s everyday lives. The most significant conclusion in this dissertation reveals that, contrary to previous scholarly arguments, the modernization projects that took place in Moscow and Kalmykia were more similar in the challenges and outcomes that local officials faced when implementing state policies.

Retos en la implementación de las normas internacionales al interior de los estados. estudio de caso: la región del Mekong y el protocolo de Palermo contra la trata de personas. (2007-2014)

El presente estudio de caso tiene como principal objetivo el de analizar la manera como las características sociopolíticas de los Estados del Mekong, específicamente en el caso de Camboya y Myanmar, dificultan la implementación de las normas enunciadas en el Protocolo de las Naciones Unidas para Prevenir, Reprimir y Sancionar la Trata de Personas, Especialmente Mujeres y Niños, también conocido como el Protocolo de Palermo. En este sentido, se parte de las características principales del Protocolo y de la manera como el tráfico de personas se presenta en el Mekong para posteriormente analizar la forma como la corrupción, la impunidad y la desigualdad de género representan retos sociopolíticos que obstruyen la implementación de los mandatos internacionales enmarcados en este instrumento