Protecting human subjects of research.

Mode of access: Internet.

Annual Contractor's Conference of the Artificial Kidney Program of the National Institute of Arthritis, Metabolism, and Digestive Diseases; proceedings

Mode of access: Internet.

Health benefits of pets : summary of working group : NIH Technology Assessment Workshop, September 10-11, 1987.

Shipping list no.: 88-461-P.

Our future selves : a research plan toward understanding aging, of the Department of Health, Education and Welfare /

Previously published in 1977 (DHEW publication ; no. (NIH) 77-1096).

The Comprehensive Health Manpower Training Act of 1971; what it means to schools of health professions. February 1972.

Mode of access: Internet.

Compendium of legally and administratively defined missions of the various research supporting divisions of the Public Health Service; a working draft for administrative purposes.

Mode of access: Internet.

Manpower for medical research, requirements and resources, 1965-1970. A report for the Subcommittee on Depts. of Labor and Health, Education and Welfare ... of the Committee on Appropriations, House of Representatives.

87th Congress, 2d sess. House.

NIH Animal Center.

Mode of access: Internet.

Establishments and products licensed under section 351 of the Public Health Service Act /

Description based on: June 1982.

A history of the National Library of Medicine : the nation's treasury of medical knowledge /

S/N 017-052-00224-4

Cystic fibrosis : a disease in search of ideas.

v. 1 Basic sciences.--v. 2 Clinical sciences.

Fact sheet : Health professions educational assistance act of 1976 (PL 94-484): amended by Health services extension act of 1977 (PL 95-83, Title III) and Health professions education amendments of l977 (PL 95-215).

Mode of access: Internet.

Assessing training and professional development needs of library staff. Report for National Library of Health

Urquhart, C., Spink, S. & Thomas, R., Assessing training and professional development needs of library staff. Report for National Library of Health. (2005). Aberystwyth: Department of Information Studies, University of Wales Aberystwyth Sponsorship: National Library for Health (NHS Information Authority)

Toward the optimal dose metric in continuous renal replacement therapy

Purpose: There is no consensus on the optimal method to measure delivered dialysis dose in patients with acute kidney injury (AKI). The use of direct dialysate-side quantification of dose in preference to the use of formal blood-based urea kinetic modeling and simplified blood urea nitrogen (BUN) methods has been recommended for dose assessment in critically-ill patients with AKI. We evaluate six different blood-side and dialysate-side methods for dose quantification. Methods: We examined data from 52 critically-ill patients with AKI requiring dialysis. All patients were treated with pre-dilution CWHDF and regional citrate anticoagulation. Delivered dose was calculated using blood-side and dialysis-side kinetics. Filter function was assessed during the entire course of therapy by calculating BUN to dialysis fluid urea nitrogen (FUN) ratios q/12 hours. Results: Median daily treatment time was 1,413 min (1,260-1,440). The median observed effluent volume per treatment was 2,355 mL/h (2,060-2,863) (p<0.001). Urea mass removal rate was 13.0 +/- 7.6 mg/min. Both EKR (r(2)=0.250; p<0.001) and K-D (r(2)=0.409; p<0.001) showed a good correlation with actual solute removal. EKR and K-D presented a decline in their values that was related to the decrease in filter function assessed by the FUN/BUN ratio. Conclusions: Effluent rate (ml/kg/h) can only empirically provide an estimated of dose in CRRT. For clinical practice, we recommend that the delivered dose should be measured and expressed as K-D. EKR also constitutes a good method for dose comparisons over time and across modalities.