Geography, skills and careers patterns at the boundary of creativity & innovation: digital technology and creative arts graduates in the UK

In the last decades, research on knowledge economies has taken central stage. Within this broader research field, research on the role of digital technologies and the creative industries has become increasingly important for researchers, academics and policy makers with particular focus on their development, supply-chains and models of production. Furthermore, many have recognised that, despite the important role played by digital technologies and innovation in the development of the creative industries, these dynamics are hard to capture and quantify. Digital technologies are embedded in the production and market structures of the creative industries and are also partially distinct and discernible from it. They also seem to play a key role in innovation of access and delivery of creative content. This chapter tries to assess the role played by digital technologies focusing on a key element of their implementation and application: human capital. Using student micro-data collected by the Higher Education Statistical Agency (HESA) in the United Kingdom, we explore the characteristics and location patterns of graduates who entered the creative industries, specifically comparing graduates in the creative arts and graduates from digital technology subjects. We highlight patterns of geographical specialisation but also how different context are able to better integrate creativity and innovation in their workforce. The chapter deals specifically with understanding whether these skills are uniformly embedded across the creative sector or are concentrated in specific sub-sectors of the creative industries. Furthermore, it explores the role that these graduates play in different sub-sector of the creative economy, their economic rewards and their geographical determinants.

Indole ring oxidation by activated leukocytes prevents the production of hypochlorous acid

Hypochlorous acid (HOCl) released by activated leukocytes has been implicated in the tissue damage that characterizes chronic inflammatory diseases. In this investigation, 14 indole derivatives, including metabolites such as melatonin, tryptophan and indole-3-acetic acid, were screened for their ability to inhibit the generation of this endogenous oxidant by stimulated leukocytes. The release of HOCl was measured by the production of taurine-chloramine when the leukocytes (2 x 10(6) cells/mL) were incubated at 37ºC in 10 mM phosphate-buffered saline, pH 7.4, for 30 min with 5 mM taurine and stimulated with 100 nM phorbol-12-myristate acetate. Irrespective of the group substituted in the indole ring, all the compounds tested including indole, 2-methylindole, 3-methylindole, 2,3-dimethylindole, 2,5-dimethylindole, 2-phenylindole, 5-methoxyindole, 6-methoxyindole, 5-methoxy-2-methylindole, melatonin, tryptophan, indole-3-acetic acid, 5-methoxy-2-methyl-3-indole-acetic acid, and indomethacin (10 µM) inhibited the chlorinating activity of myeloperoxidase (MPO) in the 23-72% range. The compounds 3-methylindole and indole-3-acetic acid were chosen as representative of indole derivatives in a dose-response study using purified MPO. The IC50 obtained were 0.10 ± 0.03 and 5.0 ± 1.0 µM (N = 13), respectively. These compounds did not affect the peroxidation activity of MPO or the production of superoxide anion by stimulated leukocytes. By following the spectral change of MPO during the enzyme turnover, the inhibition of HOCl production can be explained on the basis of the accumulation of the redox form compound-II (MPO-II), which is an inactive chlorinating species. These results show that indole derivatives are effective and selective inhibitors of MPO-chlorinating activity.

O zoológico existencialista de Edward Albee

Pós-graduação em Estudos Literários - FCLAR

Dr. Edward (Ted) Elliot Eulogy

Kathy and Susie, members of the faculty, and staff of the School of Natural Resource Sciences, ladies and gentlemen. There are some things in this world that, try as we may, just cannot be adequately accomplished. One of those things, for me at least, is to express adequately what I feel about the passing of Dr. Edward (Ted) Elliot. Ted came to this University of Nebraska a few months before I arrived, and it was my distinct honor to count him among my friends at this great University. Ted was a man of exceptional scientific standing and wisdom, and his loss leaves a void in all of our lives that will not be readily filled.

Na 1 Nachlass Max Horkheimer, 63 - Korrespondenzen u.a. mit der American Philosophical Association (p. II 3, 1-132)

Drucksachen und Briefwechsel von der American Philosophical Association, 1942-1949; 2 Briefe von Max Horkheimer an Eugene N. Anderson, 25.05.1942; 1 Briefabschrift an Franz Neumann, 29.04.1942; 3 Briefe zwischen Walter L. Arensberg und Max Horkheimer, 1941; 17 Brief und Beilagen zwischen Aufbau [Zeitschrift] und Max Horkheimer, 1942-1948; 8 Briefe und Beilage ziwschen Bruno Franco Avardi und Max Horkheimer [Pollock], 1942-1943; 21 Briefe und Beilage zwischen Edward N. Barnhart von der University of California und Max Horkheimer, 1947-1949; 5 Briefe zwischen Salo W. Baron und Max Horkheimer, 1945; 5 Briefe zwischen Gertrude Bauer und Max Horkheimer, 1941-1946; 1 Brief und Beilage von Ralph L. Beals von der University of California an Max Horkheimer, 1947-1948; 5 Briefe zwischen Howard Becker und Max Horkheimer, 1948; 1 Brief und Beilage von Frank Beckwith an Max Horkheimer, 1944; 1 Brief zwischen Bruno Bettelheim und Max Horkheimer, 1944-1949 sowie 1 Manuskript von Bruno Bettelheim: The Thematic Apperception Test as an Educational and Therapeutic Device;

Letter from Edward Wigglesworth to John Lowell, 1781 January 3

Four leaves containing a four-and-a-half-page letter in the hand of Professor Edward Wigglesworth to John Lowell dated January 3, 1781. In the letter, Professor Wigglesworth describes the issues related to the deprecating value of paper money and the salaries of Harvard officers, and he provides recommendations for the General Court's grants to the College.

Draft of law related to the settling of chambers after Commencement, 1742

One-page handwritten draft of a law created by the president and tutors requiring juniors to inform the Faculty of their intent to stay in dormitory rooms following Commencement. The document is undated and unsigned, but appears to be in the hand of President Edward Holyoke, and has a note in shorthand in the left margin. The text is included in College Book IV and was presented at a meeting of the Harvard Corporation on September 6, 1742.

Student mathematical proofs by Edward Stephen (?) Wigglesworth, 1788

Sheet with two handwritten mathematical proofs signed "Wigglesworth, 1788," likely referring Harvard student Edward Stephen Wigglesworth. The first proof, titled "Problem 1st," examines a prompt beginning, "Given the distance between the Centers of the Sun and Planet, and their quantities of matter; to find a place where a body will be attracted to neither of them." The second proof, titled "Problem 2d," begins "A & B having returned from a journey, had riden [sic] so far that if the square of the number of miles..." and asks "how many miles did each of them travel?"

Commonplace book of John Holyoke, 1662 - May 1663

This unbound commonplace book was kept by John Holyoke during 1662 and 1663. The volume contains chiefly religious quotations and sermon notes (possibly of sermons preached by Holyoke himself), in English, Latin and Greek. Both ends of the volume were used to begin writing: the front page reads “Johannes Holyoke, adjunctu occupatu, May-1663” and the rear page reads “Johannes Holyoke [illegible] 1662.” The texts do not follow a straight tête-bêche model, where one text is upside down in relation to the other; rather, the texts change direction several times within the volume. The volume also includes part of letter sent to Holyoke’s grandfather Pynchon, September 16, 16?? [date illegible], as well as a series of alphabetically arranged quotations.

Student notebook of Marston Cabot, ca. 1720-1735

This leather-bound volume contains excerpts copied by Marston Cabot from books he read while he was a student at Harvard in 1723. The volume includes extracts from Charles Morton's 1687 Compendium Physicae (titled "of Phisicks" by Cabot), Dr. Adriani Heereboord (Adrianus Heereboord), Philosophia Naturalis and Johanne-Henrico Alstedio’s (John Henry Alsted) geometry text Compendium Geometria. The excerpts from Compendium Geometria include both figures and text, primarily in Latin with some Greek. The volume also includes “Theses quaedam extractae potissimum ex Enchiridio Metaphysico Domini Johannis Clerici" a précis of Jean Le Clerc's Ontologia et Pneumatologia made by Jonathan Remington, a Harvard Tutor from 1703 to 1711, to serve in place of printed textbooks. The names Jonathan Jackson and Edward Jackson are written on the inside cover, suggesting the book may have been handed down to Edward Jackson (Class of 1726) and his son Jonathan Jackson (Class of 1761). The text of the volume is in Marston Cabot's hand.

Report ...

"Chapters IV, XVI and XVII are based on the relevant parts of Professor Engledow's Report on agriculture in the West Indies which is published separately as Cmd. 6608."

Human rights in Haiti : hearing before the Subcommittee on International Organizations of the Committee on International Relations, House of Representatives, Ninety-fourth Congress, first session, November 18, 1975.

"Report of Senator Edward W. Brooke, 'United States foreign assistance for Haiti', April 1974": p. 73-120.

Reminiscences and memoirs of North Carolina and eminent North Carolinians.

Prefatory matter: Memoir of the author, by J.S. Fowler.--North Carolina in the colonial period, by D. R. Goodloe.--Early German Settlers in eastern Cabarrus Co., by Rufus Barringer.--Biographical sketch of Dr. Edward Warren (Bey)--Genealogies of Blount, Barringer, Clark Haywood & Phifer families.

De termino Paschae anno xvij. Edwardi quarti.

On label mounted on cover: Year book, 17, Edward IV. Tottel, 1583. R338.

A history of our own times ...

I-II. From the accession of Queen Victoria to the general election of 1880.--III. From 1880 to the diamond jubilee.--IV-V. From the diamond jubilee, 1897, to the accession of King Edward VII.