985 resultados para Harlem Heights, Battle of, N.Y., 1776.
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This article underscores the complex relationship between national concerns and dramatic criticism by interrogating the role of theatre in the creation of a 'national culture' during the last few decades of the Ancien regime. The author focuses more specifically on the forms of patriotism proposed by Pierre-Laurent De Belloy, author of Le Siege de Calais, France's "first tragedy in which the nation is given the pleasure to take an interest in itself," as well as by his adversaries and his allies. The version of patriotism proffered by De Belloy - a 'fatherland' that he defines as both bourgeois and monarchical - renders problematic several aesthetic and political norms in place in 1765. The author thus responds modestly to one of the most essential questions posed by research on eighteenth-century political and cultural history: how did patriotism operate before the French Revolution?
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Neuropeptide Y (NPY), which is found in high concentrations in several regions of the brain including nuclei of the brain stem and in nerve fibers surrounding cerebral vessels, has been proposed to play a role in regulating cerebral blood flow (CBF) and systemic vegetative functions. Since CBF is altered during meningitis, we examined whether NPY concentrations changed in various regions of the rabbit brain in response to experimental pneumococcal meningitis. Changes were most pronounced in the medulla, where NPY concentration increased threefold after 48 h of infection. Concomitantly, there was an increase in NPY immunoreactive fibers surrounding small vessels in the dorsolateral medulla, especially in the nucleus tractus solitarius. These results suggest that NPY may play a role in inducing some of the hemodynamic changes seen during pneumococcal meningitis.
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Fil: Massini Correas, Carlos I.. Universidad de Mendoza
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Este estudio tiene como primer objetivo conocer el volumen y evolución de la producción científica española en psicología a partir de las bases de datos del Web of Science (Thomson Reuters) y Scopus (Elsevier), durante el periodo 2000-2009. A partir de allí, se propone determinar cuáles son las revistas científicas más utilizadas por los psicólogos españoles para difundir sus trabajos a nivel internacional y comparar la cobertura y solapamiento de revistas y documentos que presentan ambas bases de datos. Se ofrecen datos cuantitativos, se estudia la posible correlación entre las dos bases de datos y se analiza el solapamiento de documentos y de revistas, el modelo de crecimiento que presentan y la dispersión de los trabajos, entre otros. Los resultados muestran que ambos sistemas de información son complementarios pero no excluyentes, así como la relevancia e importancia de las revistas españolas de psicología en la difusión de la investigación de esta disciplina en el contexto internacional de la ciencia
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Este estudio tiene como primer objetivo conocer el volumen y evolución de la producción científica española en psicología a partir de las bases de datos del Web of Science (Thomson Reuters) y Scopus (Elsevier), durante el periodo 2000-2009. A partir de allí, se propone determinar cuáles son las revistas científicas más utilizadas por los psicólogos españoles para difundir sus trabajos a nivel internacional y comparar la cobertura y solapamiento de revistas y documentos que presentan ambas bases de datos. Se ofrecen datos cuantitativos, se estudia la posible correlación entre las dos bases de datos y se analiza el solapamiento de documentos y de revistas, el modelo de crecimiento que presentan y la dispersión de los trabajos, entre otros. Los resultados muestran que ambos sistemas de información son complementarios pero no excluyentes, así como la relevancia e importancia de las revistas españolas de psicología en la difusión de la investigación de esta disciplina en el contexto internacional de la ciencia
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Este estudio tiene como primer objetivo conocer el volumen y evolución de la producción científica española en psicología a partir de las bases de datos del Web of Science (Thomson Reuters) y Scopus (Elsevier), durante el periodo 2000-2009. A partir de allí, se propone determinar cuáles son las revistas científicas más utilizadas por los psicólogos españoles para difundir sus trabajos a nivel internacional y comparar la cobertura y solapamiento de revistas y documentos que presentan ambas bases de datos. Se ofrecen datos cuantitativos, se estudia la posible correlación entre las dos bases de datos y se analiza el solapamiento de documentos y de revistas, el modelo de crecimiento que presentan y la dispersión de los trabajos, entre otros. Los resultados muestran que ambos sistemas de información son complementarios pero no excluyentes, así como la relevancia e importancia de las revistas españolas de psicología en la difusión de la investigación de esta disciplina en el contexto internacional de la ciencia
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In the centre of Castilla y León (extensive zone of Spain) still there are some examples of the old rural buildings linked to the economic activities that have been developed in the agrarian field. These are called chozos and casetas, and they have been erected with domed solutions using the autochthonous materi-als: the mud in the region of Tierra de Campos and the stone in the region of Montes Torozos. The influence of traditional construction techniques of both elements has generated a singular typological range rarely seen in the rest of the Península Ibérica. All different types of domes found in this place will be explained from its construction process, adding its structural capacity and energy bioclimatic qualities. -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- En el centro de Castilla y León todavía se mantienen algunos ejemplos de antiguas construcciones rurales vinculadas a las actividades económicas que se han desarrollado en el ámbito agrario. Éstas, conocidas como chozos y casetas, han sido ejecutadas con soluciones cupuliformes empleándose los materiales que más a mano se disponen, siendo el barro más característico en la región de Tierra de Campos y la piedra en la comarca de Montes Torozos. La influencia de las técnicas constructivas tradicionales de ambos elementos ha generado un abanico tipológico singular poco visto en el resto de la península. Los diferentes tipos de cúpulas encontrados se explicarán desde su proceso constructivo, añadiendo su capacidad estructural y sus cualidades bioclimáticas.
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Using autoradiographic binding methodology with monoiodinated peptide YY together with the agonists neuropeptide Y (NPY) and NPY (13–36), as well as in situ hybridization with oligonucleotide probes complementary to the NPY Y2 receptor (Y2-R) mRNA, we have studied whether or not intracerebral prion inoculation affects Y2-Rs in male CD-1 mice. Monoiodinated peptide YY binding, mainly representing Y2-Rs, was down-regulated by 85% in the CA1 strata oriens and radiatum and by 50–65% in the CA3 stratum oriens 110–140 days postinoculation. In the CA3 stratum radiatum, where the mossy fibers from the dentate granule cells project, there was a significant decrease in PYY binding at 110–120 days. Y2-R mRNA, moderately expressed both in the CA1 and CA3 pyramidal cell layers and the granule cell layer in the dentate gyrus, showed a slight, but not significant, decrease in CA3 neurons 130 days postinoculation. The results indicate that the accumulation of the scrapie prion protein in the CA1–3 region strongly inhibits NPY binding at the Y2-Rs, which, however, is only marginally due to reduced Y2-R mRNA expression. The loss of the ability of NPY to bind to inhibitory Y2-Rs may cause dysfunction of hippocampal circuits and may contribute to the clinical symptoms in mouse scrapie.
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The localization of neuropeptide Y (NPY) Y1 receptor (R) -like immunoreactivity (LI) has been studied in cerebral arteries and arterioles of the rat by immunohistochemistry using fluorescence, confocal, and electron microscopy. High levels of Y1-R-LI were observed in smooth muscle cells (SMCs) in the small arterioles of the pial arterial network, especially on the basal surface of the brain, and low levels in the major basal cerebral arteries. The levels of Y1-R-LI varied strongly between adjacent SMCs. Y1-R-LI was associated with small endocytosis vesicles, mainly on the outer surface of the SMCs, but also on their endothelial side and often laterally at the interface between two SMCs. NPY-immunoreactive (Ir) nerve fibers could not be detected in association with the Y1-R-rich small arterioles but only around arteries with low Y1-R levels. A dense network of central NPY-Ir nerve fibers in the superficial layers of the brain was lying close to the strongly Y1-R-Ir small arterioles. The results indicate that NPY has a profound effect on small arterioles of the brain acting on Y1-Rs, both on the peripheral and luminal side of the SMCs. However, the source of the endogenous ligand, NPY, remains unclear. NPY released from central neurons may play a role, in addition to blood-borne NPY.
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Genes located on the mammalian Y chromosome outside of the pseudoautosomal region do not recombine with those on the X and are predicted to either undergo selection for male function or gradually degenerate because of an accumulation of deleterious mutations. Here, phylogenetic analyses of X-Y homologues, Zfx and Zfy, among 26 felid species indicate two ancestral episodes of directed genetic exchange (ectopic gene conversion) from X to Y: once during the evolution of pallas cat and once in a common predecessor of ocelot lineage species. Replacement of the more rapidly evolving Y homologue with the evolutionarily constrained X copy may represent a mechanism for adaptive editing of functional genes on the nonrecombining region of the mammalian Y chromosome.