989 resultados para HMB-45


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Autism is a neurodevelopmental disorder characterized by deficits in social interaction and social communication, as well as by the presence of repetitive and stereotyped behaviors and interests. Brodmann areas 44 and 45 in the inferior frontal cortex, which are involved in language processing, imitation function, and sociality processing networks, have been implicated in this complex disorder. Using a stereologic approach, this study aims to explore the presence of neuropathological differences in areas 44 and 45 in patients with autism compared to age- and hemisphere-matched controls. Based on previous evidence in the fusiform gyrus, we expected to find a decrease in the number and size of pyramidal neurons as well as an increase in volume of layers III, V, and VI in patients with autism. We observed significantly smaller pyramidal neurons in patients with autism compared to controls, although there was no difference in pyramidal neuron numbers or layer volumes. The reduced pyramidal neuron size suggests that a certain degree of dysfunction of areas 44 and 45 plays a role in the pathology of autism. Our results also support previous studies that have shown specific cellular neuropathology in autism with regionally specific reduction in neuron size, and provide further evidence for the possible involvement of the mirror neuron system, as well as impairment of neuronal networks relevant to communication and social behaviors, in this disorder.

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The Iowa Influenza Surveillance Network (IISN) was established in 2004, though surveillance has been conducted at the Iowa Department of Public Health. Schools and long-term care facilities report data weekly into a Web-based reporting system. Schools report the number of students absent due to illness and the total enrolled. Long-term care facilities report cases of influenza and vaccination status of each case. Both passively report outbreaks of illness, including influenza, to IDPH.

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This article provides an in-depth study of long-term female unemployment in Catalonia.Long-term unemployment statistics reveal which social groups are most likely to experience difficulty re-entering the labour market. In this case, we found that women are mainly affected by this type of labour exclusion, in particular poorly qualified, working-class women who are aged over 45 and with family responsibilities.The article aims to explore how the overlapping of factors such as gender, age, social class, origin and the division of work based on gender are related to long-term female unemployment. Moreover, we were able to detect which conceptual tools provide us with the production/reproduction paradigm so as to be able to analyse the future of female unemployment. The methodology we used combines quantitative and qualitative approaches. On the one hand, the analysis of secondary statistical data focusing on Catalonia is useful in understanding the situation from a macro-social perspective. On the other hand, an exploratory discussion group enables us to investigate social imaginary practises among unemployed working class women aged over 45. This discussion group was held in Igualada -capital of the Anoia region - an area of Catalonia deeply affected by unemployment in the current economic crisis.

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En els darrers anys s’han publicat diversos articles que descriuen l’epidemiologia de les malalties i lesions patides per persones que practiquen diferents esports. Aquestes investigacions s’han fet a partir de les dades reco· llides durant períodes d’entrenament de diversa durada o bé durant unes competicions concretes, com poden ser uns Jocs Olímpics. L’objectiu del present estudi va ser el de recollir i analitzar les dades epidemiològiques de les lesions patides per una població d’esportistes del nostre país, durant un període de temps determinat que inclou tant el temps d’entrenament com el de competició. La informació va ser recollida en el servei mèdic d’un centre d’entrenament esportiu, a partir de les dades de les visites mèdiques recollides en l’historial clínic de cada espor· tista. Es van revisar 16.925 visites mèdiques, realitzades en 45 mesos, d’esportistes d’ambdós gèneres i de 29 esports diferents. Les variables que es van analitzar van ser el tipus de lesió, les circumstàncies de producció de la lesió i la topografia de la lesió.Es va veure que el 90 % de totes les lesions es van produir durant l’entrenament. Les més freqüents van ser les agudes (75 %). Les parts del cos més afectades van ser el genoll (17 %), el turmell (12 %), el peu (11%), la cintura escapular (10 %) i la regió lumbar (10 %).

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This study examined the impact of social support and of temporal and social comparisons on well-being and selfreported health in four capital cities: Paris, Berlin, Moscow and Beijing. Based on the lifespan control theory, an integrative model investigating the influence of these coping strategies, especially on the psychological regulation of health losses, was tested on 1141 respondents aged 45 to 70 years by using structural equation modelling with multigroup comparisons. Results indicated a good fit of the model to participants' responses. In all contexts, physical weaknesses favoured the use of social and temporal comparison strategies rather than social support. Moreover, across the cities, coping strategies were oriented more toward protecting self-evaluation of health than toward enhancement of well-being. Social comparison decreased the impact of physical weaknesses on health evaluation and on well-being in the four cities, but to a lesser extent in China. Results are discussed regarding the normative cross-cultural aspects that intervene during ageing in the four urban contexts.

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L’objectiu de l’estudi és identificar el grau de coneixement que tenen les dones de 30 a 45 anys del municipi de Vallromanes sobre aspectes relacionats amb l’activitat física i la salut, així com identificar quins coneixements són més específics perquè s’adhereixin a la pràctica regular d’activitat física. A més, de comprovar quins d’aquests possibles coneixements relacionats a la promoció de la salut pública són més eficients per fer augmentar el coneixement d’aquest grup de dones i alhora fer-les conscients de la importància de l’activitat física per la salut. Així doncs, a la mostra de l’estudi han participat 35 dones. La informació ha estat recopilada a través del qüestionari per identificar els estadis de canvi de l’activitat física (Marcus, Rossi, Selby, Niaura, i Abrams, 1992) i un qüestionari elaborat específicament per aquesta investigació. Els resultats obtinguts demostren, a trets generals, que les dones que es troben en estadis de canvi on tenen conductes actives físicament o compleixen amb les recomanacions mundials d’activitat física per la salut, tenen un major grau de coneixença i conscienciació sobre coneixements relacionats amb l’activitat física i la salut. Per tant, això porta a concloure que l’augment del coneixement i conscienciació d’aquest és un motiu perquè les dones participants en l’estudi s’adhereixin a la pràctica regular d’activitat física. No obstant, cal tenir present quines estratègies de salut pública són més específiques i eficients per fer augmentar el coneixement del grup de dones estudiat i adherir-les a la pràctica.

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Soitinnus: piano, orkesteri.

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Gutenberg-lehti ilmestyi vuosina 1893-1915. Se oli perustettu ammattilehdeksi ja yhdyssiteeksi Suomen kirjanpainajille sekä äänenkannattajaksi Suomen kirjaltajaliitolle.