Library Permanently Closed: See Google

magine if you will the near perfect statefunded program. Yes, I know, such words sound like an oxymoron, given the track record of both state and federally-funded programs, past, present and undoubtedly in the future. Indeed, such words sound almost mythological in light of recent attempts by the federal government to spend us out of the current recession with still doubtful results (so far, a record deficit). Yet, you’re an imaginative individual and can put aside petty political persiflage and visualize such a program. Not only does this program do precisely what it said it would do, it does it so surprisingly well that, as a taxpayer, you’re completely astonished and whole-heartedly impressed.

Interaction of shikimic acid with shikimate kinase (Retracted Article. See vol 334, pg 967, 2005)

The crystal structure of shikimate kinase from Mycobacterium tuberculosis (MtSK) complexed with MgADP and shikimic acid (shikimate) has been determined at 2.3 Angstrom resolution, clearly revealing the amino acid residues involved in shikimate binding. In MtSK, the Glu61 strictly conserved in SK forms a hydrogen bond and salt-bridge with Arg58 and assists in positioning the guanidinium group of Arg58 for shikimate binding. The carboxyl group of shikimate interacts with Arg58, Gly81, and Arg136, and hydroxyl groups with Asp34 and Gly80. The crystal structure of MtSK-MgADP-shikimate will provide crucial information for elucidation of the mechanism of SK-catalyzed reaction and for the development of a new generation of drugs against tuberculosis. (C) 2004 Elsevier B.V. All rights reserved.

Estudo dos efeitos da compensação em derivação no desempenho dinâmico e transitório dos SEE sob o enfoque de energia transitória

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Controle coordenado de múltiplos dipositivos facts com vistas à estabilidade transitória de SEE

Pós-graduação em Engenharia Elétrica - FEIS

O uso de simulações virtuais como apoio ao currículo da SEE-SP para a disciplina de Física

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Come-See-Me Festival Records - Accession 815

The Come-See-Me Festival Records consist of records and memorabilia from the Come-See-Me Festivals since its founding in 1962. The collection contains correspondence, newspaper clippings, photographs, financial reports and papers, promotional materials, and other records and material chronicling the development of the Come-See-Me Festival in Rock Hill, SC.

Come-See-Me Festival Records - Accession 1408

The Come-See-Me Festival Records consist of papers, photographs, meeting minutes, scrapbooks, media kits, publicity kits, awards, applications, invitations, bylaws, guidelines, histories, correspondence, promotions and advertisements, posters, and memorabilia from the Come-See-Me Festivals from the 1980s to 2013.

Come-See-Me Festival Interview

In this April 21, 1978 interview, the origins and history of the Come-See-Me Festival are discussed. Included is an overview of the events for the 1978 event. This interview was conducted for inclusion into the Louise Pettus Archives and Special Collections Oral History Program

Eisströme und Schelfeise an der Küste der Amundsen See (West-Antarktis), beobachtet mit ERS-SAR /// Es stehen 2 Dateien zur Auswahl: pdf-Datei Abbildungen nur schwarz-weiss, zip-Datei Abbildungen farbig

In der vorliegenden Diplomarbeit erfolgte die Beobachtung von Eisströmen und Schelfeisen an der Küste der Amundsen See in der West-Antarktis, unter Verwendung von ERS-SAR-Amplitudenbildprodukten. Bestandteile dieser Beobachtung waren die Erstellung eines Gletscherinventares, die Erstellung von Multitemporalbildern, die Auswertung von Veränderungen der Eisfronpositionen und - schwerpunktmäßig - die Bestimmung von Eisfließgeschwindigkeiten und deren räumlicher und zeitlicher Vergleich.

Intracellular imaging of nanoparticles: is it an elemental mistake to believe what you see?

In order to understand how nanoparticles (NPs <100 nm) interact with cellular systems, potentially causing adverse effects, it is important to be able to detect and localize them within cells. Due to the small size of NPs, transmission electron microscopy (TEM) is an appropriate technique to use for visualizing NPs inside cells, since light microscopy fails to resolve them at a single particle level. However, the presence of other cellular and non-cellular nano-sized structures in TEM cell samples, which may resemble NPs in size, morphology and electron density, can obstruct the precise intracellular identification of NPs. Therefore, elemental analysis is recommended to confirm the presence of NPs inside the cell. The present study highlights the necessity to perform elemental analysis, specifically energy filtering TEM, to confirm intracellular NP localization using the example of quantum dots (QDs). Recently, QDs have gained increased attention due to their fluorescent characteristics, and possible applications for biomedical imaging have been suggested. Nevertheless, potential adverse effects cannot be excluded and some studies point to a correlation between intracellular particle localization and toxic effects. J774.A1 murine macrophage-like cells were exposed to NH2 polyethylene (PEG) QDs and elemental co-localization analysis of two elements present in the QDs (sulfur and cadmium) was performed on putative intracellular QDs with electron spectroscopic imaging (ESI). Both elements were shown on a single particle level and QDs were confirmed to be located inside intracellular vesicles. Nevertheless, ESI analysis showed that not all nano-sized structures, initially identified as QDs, were confirmed. This observation emphasizes the necessity to perform elemental analysis when investigating intracellular NP localization using TEM.