Treatment of slipped capital femoral epiphysis with a modified Dunn procedure

Surgical procedures with use of traditional techniques to reposition the proximal femoral epiphysis in the treatment of slipped capital femoral epiphysis are associated with a high rate of femoral head osteonecrosis. Therefore, most surgeons advocate in situ fixation of the slipped epiphysis with acceptance of any persistent deformity in the proximal part of the femur. This residual deformity can lead to secondary osteoarthritis resulting from femoroacetabular cam impingement.

Urinary soluble HLA-DR is a potential biomarker for acute renal transplant rejection

BACKGROUND.: Urine is a potentially rich source of biomarkers for monitoring kidney dysfunction. In this study, we have investigated the potential of soluble human leukocyte antigen (sHLA)-DR in the urine for noninvasive monitoring of renal transplant patients. METHODS.: Urinary soluble HLA-DR levels were measured by sandwich enzyme-linked immunosorbent assay in 103 patients with renal diseases or after renal transplantation. sHLA-DR in urine was characterized by Western blotting and mass spectrometry. RESULTS.: Acute graft rejection was associated with a significantly elevated level of urinary sHLA-DR (P<0.0001), compared with recipients with stable graft function or healthy individuals. A receiver operating characteristic curve analysis showed the area under the curve to be 0.88 (P<0.001). At a selected threshold, the sensitivity was 80% and specificity was 98% for detection of acute renal transplant rejection. sHLA-DR was not exosomally associated and was of lower molecular weight compared with the HLA-DR expressed as heterodimer on the plasma membrane of antigen-presenting cells. CONCLUSIONS.: sHLA-DR excreted into urine is a promising indicator of renal transplant rejection.

Will Whole-Tree Harvest of Jack Pine (Pinus banksiana) deplete soil nutrients in low-productivity sand soils?

In 2009 and 2010 a study was conducted on the Hiawatha National Forest (HNF) to determine if whole-tree harvest (WTH) of jack pine would deplete the soil nutrients in the very coarse-textured Rubicon soil. WTH is restricted on Rubicon sand in order to preserve the soil fertility, but the increasing construction of biomass-fueled power plants is expected to increase the demand for forest biomass. The specific objectives of this study were to estimate biomass and nutrient content of above- and below-ground tree components in mature jack pine (Pinus banksiana) stands growing on a coarse-textured, low-productivity soil, determine pools of total C and N and exchangeable soil cations in Rubicon sand, and to compare the possible impacts of conventional stem-only harvest (CH) and WTH on soil nutrient pools and the implications for productivity of subsequent rotations. Four even-aged jack pine stands on Rubicon soil were studied. Allometric equations were used to estimate above-ground biomass and nutrients, and soil samples from each stand were taken for physical and chemical analysis. Results indicate that WTH will result in cation deficits in all stands, with exceptionally large Ca deficits occurring in two stands. Where a deficit does not occur, the cation surplus is small and, chemical weathering and atmospheric deposition is not anticipated to replace the removed cations. CH will result in a surplus of cations, and will likely not result in productivity declines during the first rotation. However even under CH, the surplus is small, and chemical weathering and atmospheric deposition will not supply enough cations for the second rotation.

Capital realignment for moderate and severe SCFE using a modified Dunn procedure

Moderate to severe slipped capital femoral epiphysis leads to premature osteoarthritis resulting from femoroacetabular impingement. We believe surgical correction at the site of deformity through capital reorientation is the best procedure to fully correct the deformity but has traditionally been associated with high rates of osteonecrosis. We describe a modified capital reorientation procedure performed through a surgical dislocation approach. We followed 40 patients for a minimum of 1 year and 3 years from two institutions. No patient developed osteonecrosis or chondrolysis. Slip angle was corrected to 4 degrees to 8 degrees and the mean alpha angle after correction was 40.6 degrees. Articular cartilage damage, full-thickness loss, and delamination were observed at the time of surgery, especially in the stable slips. This technique appears to have an acceptable complication rate and appears reproducible for full correction of moderate to severe slipped capital femoral epiphyses with open physes.

Jack-of-all-trades effects drive biodiversity–ecosystem multifunctionality relationships in European forests

There is considerable evidence that biodiversity promotes multiple ecosystem functions (multifunctionality), thus ensuring the delivery of ecosystem services important for human well-being. However, the mechanisms underlying this relationship are poorly understood, especially in natural ecosystems. We develop a novel approach to partition biodiversity effects on multifunctionality into three mechanisms and apply this to European forest data. We show that throughout Europe, tree diversity is positively related with multifunctionality when moderate levels of functioning are required, but negatively when very high function levels are desired. For two well-known mechanisms, ‘complementarity’ and ‘selection’, we detect only minor effects on multifunctionality. Instead a third, so far overlooked mechanism, the ‘jack-of-all-trades’ effect, caused by the averaging of individual species effects on function, drives observed patterns. Simulations demonstrate that jack-of-all-trades effects occur whenever species effects on different functions are not perfectly correlated, meaning they may contribute to diversity–multifunctionality relationships in many of the world’s ecosystems.

Jack London: Die Herrin des großen Hauses [Rezension]

J-e.

Revision der im Exsiccat "Kryptogamen Badens von Jack, Leiner und Stitzenberger" enthaltenen Chytridiaceen, Peronosporeen, Ustilagineen und Uredineen

Von G. Lagerheim

Dr. Joseph Bernhard Jack

Anonym

Henry Neville als Jack Dudley, Rollenbild, Kniestück

Signatur des Originals: S 36/F09412

Puntos de vista acerca de la revolución mexicana en John Reed y Jack London

En el presente trabajo me centraré en el análisis comparado de "El mexicano" (1911) de Jack London con México insurgente (1914) y tres cuentos incluidos en Hija de la revolución y otros cuentos: "Mac-American" (1914), "Cuadros de México" (1914) y ?Endimión o en la frontera? (1916) de John Reed. El objetivo que me propongo es el de establecer una correlación entre dos autores que abordan en sus escritos el tema de la revolución mexicana a partir de un análisis comparado de las obras antes mencionadas. Las primeras hipótesis que construí parten de la base común de ofrecernos una visión particular del fenómeno político, social y económico que marcó a México a principios del siglo XX: la revolución mexicana. Tomando como eje de comparación esta semejanza pude ir encontrando, a lo largo del análisis, puntos de divergencia en el modo en que estos dos escritores abordaron este mismo suceso. Por un lado se sitúa London, quien construye en "El mexicano" una representación simplista tanto de las características del revolucionario y de las motivaciones que lo llevan a decidirse por la lucha armada, como del régimen al que éste se opone. Frente a esta representación populista de la revolución mexicana, Reed pone en primer plano, tanto en México insurgente como en sus cuentos, lo complejo de ese mismo hecho ya sea por la confusión de los revolucionarios en torno al trasfondo ideológico que la revolución conllevó o por las diferentes motivaciones que los impulsaron a participar en la misma. Esta tesis inicial de la complejidad de la representación en Reed se sustenta, en el plano formal, por lo que podríamos denominar "técnica del montaje mural", en relación con el movimiento artístico denominado "muralismo" que se desarrolló en México luego de la revolución