De La Ribera de Deusto a Zorrotzaurre. Un siglo de planeamiento urbanístico en la Vega de Deusto

795 p.

Letras, 1982, nº 4 (número completo)

Contenido: Apuntes sobre crítica semiológica y significados en el Poema del Cid / Carrizo Rueda, Sofía – Naturaleza y paisaje en la Soledad I de Góngora / Elsa L. Di Santo – Experimentación y vanguardia en el teatro argentino de las últimas décadas / Perla Zayas de Lima – El reflejo del mundo en la obra de Luis Cernuda / Luis Martínez Cuitiño – Aproximaciones a Benito Lynch y su obra / María Luisa Montero – Tres maestros de la narrativa española contemporánea / Boris Osés – Indianismo e indigenismo en la poesía de la Revolución / Fernando Rosemberg – Sobre algunos aspectos lingüísticos y simbólicos del puente del Romance Viejo de la Doncella Guerrera / Aquilino Suárez Pallasá – Experiencia y sabiduría al margen de la novela picaresca / Teresa Herraiz de Tresca – Los estudios de Menéndez y Pelayo y María Rosa Lida sobre “La Celestina” / Lía Noemí Uriarte Rebaudi – Reseñas bibliográficas

Revista de Psicología, 2006, Vol. 2 N°4 (número completo)

La subjetividad como definición ontológica del campo psi; repercusiones en la construcción de la psicología / Fernando Luis González Rey -- Notas para una reformulación de la epistemología junguiana. Segunda Parte / Bernardo Nante -- Surgimiento de la psicología como ciencia natural en Estados Unidos / Hugo Klappenbach -- Consideraciones filosóficas sobre el amor a sí mismo en la obra de Freud / Juan Pablo Roldan -- Alteraciones cognitivas en personas con Parálisis Cerebral / Ignacio Montero -- Estudio de las diferencias de los Contenidos entre hombres y mujeres de la población italiana en las diez Láminas Rorscharch / Roberto Cicioni ; Martí Aguilà Usart ; Vito Rocco Genzano -- Motivación, nivel socio-económico y proyecto educativo / Stella Maris Vázquez -- Recensiones bibliográficas

The Loss of Functional Caspase-12 in Europe Is a Pre-Neolithic Event

6 p.

Ancient DNA from Hunter-Gatherer and Farmer Groups from Northern Spain Supports a Random Dispersion Model for the Neolithic Expansion into Europe

10 p.

Ontzigintza Arkitektura Eskola Erandion

Ontzigintza Arkitektura Eskola garatzen da Erandion, Bilboko itsasadarrean, ontzigintza eta industriaren sektorean gune historiko garrantzitsua. Proposamena, izango duen ontzigintzaren irudia erakusten du kanpotik, inguruko paisaian integratuz. Espazio publikoaren garrantzia ere nabarmentzen saiatu da ere, hau eraikinean murgilduz estalkiaren bitartez.

Escuela de Arquitectura Naval en Erandio

Se desarrolla el proyecto de una Escuela de Arquitectura Naval como un ejemplo claro de intervención en la estrategia de rehabilitación del margen derecho de la Ría del Nervión propuesto en el Plan Territorial Parcial de Bilbao Metropolitano. La implantación del nuevo edificio y su integración en el entorno será la premisa principal. El proyecto, para ello, se sustentara en dos pilares que serán el pasado naval y el fuerte carácter industrial que rodea la parcela.

The Interplay between Natural Selection and Susceptibility to Melanoma on Allele 374F of SLC45A2 Gene in a South European Population

We aimed to study the selective pressures interacting on SLC45A2 to investigate the interplay between selection and susceptibility to disease. Thus, we enrolled 500 volunteers from a geographically limited population (Basques from the North of Spain) and by resequencing the whole coding region and intron 5 of the 34 most and the 34 least pigmented individuals according to the reflectance distribution, we observed that the polymorphism Leu374Phe (L374F, rs16891982) was statistically associated with skin color variability within this sample. In particular, allele 374F was significantly more frequent among the individuals with lighter skin. Further genotyping an independent set of 558 individuals of a geographically wider population with known ancestry in the Spanish population also revealed that the frequency of L374F was significantly correlated with the incident UV radiation intensity. Selection tests suggest that allele 374F is being positively selected in South Europeans, thus indicating that depigmentation is an adaptive process. Interestingly, by genotyping 119 melanoma samples, we show that this variant is also associated with an increased susceptibility to melanoma in our populations. The ultimate driving force for this adaptation is unknown, but it is compatible with the vitamin D hypothesis. This shows that molecular evolution analysis can be used as a useful technology to predict phenotypic and biomedical consequences in humans.

Informazioaren komunikazioa eta datu eta bilduma digitaletarako sarbidea

236 p.

The Carpathian range represents a weak genetic barrier in South-East Europe

Background: In the present study we have assessed whether the Carpathian Mountains represent a genetic barrier in East Europe. Therefore, we have analyzed the mtDNA of 128 native individuals of Romania: 62 of them from the North of Romania, and 66 from South Romania. Results: We have analyzed their mtDNA variability in the context of other European and Near Eastern populations through multivariate analyses. The results show that regarding the mtDNA haplogroup and haplotype distributions the Romanian groups living outside the Carpathian range (South Romania) displayed some degree of genetic differentiation compared to those living within the Carpahian range (North Romania). Conclusion: The main differentiation between the mtDNA variability of the groups from North and South Romania can be attributed to the demographic movements from East to West (prehistoric or historic) that differently affected in these regions, suggesting that the Carpathian mountain range represents a weak genetic barrier in South-East Europe.

Análisis de viabilidad de un proyecto empresarial vinculado al transporte fluvial

En este informe se analiza y comprueba la viabilidad económico-financiera de un proyecto empresarial para la prestación de un servicio de transporte fluvial de personas por la ría de Bilbao. Este proyecto consiste en el transporte de personas a lo largo de la ría del Nervión utilizando dos buques. El recorrido abarca desde el Casco Viejo de Bilbao hasta la terminal de cruceros de Las Arenas.

Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation

We analysed the whole-genome transcriptional profile of 6 cell lines of dark melanocytes (DM) and 6 of light melanocytes (LM) at basal conditions and after ultraviolet-B (UVB) radiation at different time points to investigate the mechanisms by which melanocytes protect human skin from the damaging effects of UVB. Further, we assessed the effect of different keratinocyte-conditioned media (KCM+ and KCM-) on melanocytes. Our results suggest that an interaction between ribosomal proteins and the P53 signaling pathway may occur in response to UVB in both DM and LM. We also observed that DM and LM show differentially expressed genes after irradiation, in particular at the first 6h after UVB. These are mainly associated with inflammatory reactions, cell survival or melanoma. Furthermore, the culture with KCM+ compared with KCM- had a noticeable effect on LM. This effect includes the activation of various signaling pathways such as the mTOR pathway, involved in the regulation of cell metabolism, growth, proliferation and survival. Finally, the comparison of the transcriptional profiles between LM and DM under basal conditions, and the application of natural selection tests in human populations allowed us to support the significant evolutionary role of MIF and ATP6V0B in the pigmentary phenotype.

Ancient DNA from South-East Europe Reveals Different Events during Early and Middle Neolithic Influencing the European Genetic Heritage

The importance of the process of Neolithization for the genetic make-up of European populations has been hotly debated, with shifting hypotheses from a demic diffusion (DD) to a cultural diffusion (CD) model. In this regard, ancient DNA data from the Balkan Peninsula, which is an important source of information to assess the process of Neolithization in Europe, is however missing. In the present study we show genetic information on ancient populations of the South-East of Europe. We assessed mtDNA from ten sites from the current territory of Romania, spanning a time-period from the Early Neolithic to the Late Bronze Age. mtDNA data from Early Neolithic farmers of the Starcevo Cris culture in Romania (Carcea, Gura Baciului and Negrilesti sites), confirm their genetic relationship with those of the LBK culture (Linienbandkeramik Kultur) in Central Europe, and they show little genetic continuity with modern European populations. On the other hand, populations of the Middle-Late Neolithic (Boian, Zau and Gumelnita cultures), supposedly a second wave of Neolithic migration from Anatolia, had a much stronger effect on the genetic heritage of the European populations. In contrast, we find a smaller contribution of Late Bronze Age migrations to the genetic composition of Europeans. Based on these findings, we propose that permeation of mtDNA lineages from a second wave of Middle-Late Neolithic migration from North-West Anatolia into the Balkan Peninsula and Central Europe represent an important contribution to the genetic shift between Early and Late Neolithic populations in Europe, and consequently to the genetic make-up of modern European populations.

Estimacion de sexo y edad a nivel esqueletico: aplicacion forense y antropologica

[ES] La estimación del sexo y la edad son esenciales para la identificación individual de restos humanos y para el conocimiento e interpretación de la variabilidad biológica del pasado. El objetivo de este trabajo es la elaboración de un protocolo metodológico de análisis morfológico y morfométrico, para la estimación del sexo en adultos y de la edad en subadultos y adultos. Las principales metodologías incluidas en este trabajo pueden emplearse en restos esqueléticos de procedencia europea. Se realizó una revisión bibliográfica en revistas de ámbito forense y antropológico a fin de reunir un conjunto de metodologías aplicables tanto a esqueletos completos como parciales. Finalmente, en la elección de los métodos incluidos en este protocolo se tuvieron en cuenta dos criterios: la bondad de ajuste y el grado de complejidad del método.

Modernización y cambio social en Bizkaia durante el siglo industrial, 1877-1975. Claves de un proceso

375 p.