Quotlibeta septem ; vna cum tractatu de sacramento altaris / venerabilis inceptoris fratris Guilhelmi de Ockam anglici sacre theologie magistri de ordine fratrum minoru[m].

Lugar y fecha de imp. tomados del colofón

Tractat[us] / venerabilis Inceptoris Guilhelmi ocka[m] desacramento altaris.

Huecos para iniciales con letras de aviso

Mitochondrial carbonic anhydrase CA VB: Differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles

A cDNA for a second mouse mitochondrial carbonic anhydrase (CA) called CA VB was identified by homology to the previously characterized murine CA V, now called CA VA. The full-length cDNA encodes a 317-aa precursor that contains a 33-aa classical mitochondrial leader sequence. Comparison of products expressed from cDNAs for murine CA VB and CA VA in COS cells revealed that both expressed active CAs that localized in mitochondria, and showed comparable activities in crude extracts and in mitochondria isolated from transfected COS cells. Northern blot analyses of total RNAs from mouse tissues and Western blot analyses of mouse tissue homogenates showed differences in tissue-specific expression between CA VB and CA VA. CA VB was readily detected in most tissues, while CA VA expression was limited to liver, skeletal muscle, and kidney. The human orthologue of murine CA VB was recently reported also. Comparison of the CA domain sequence of human CA VB with that reported here shows that the CA domains of CA VB are much more highly conserved between mouse and human (95% identity) than the CA domains of mouse and human CA VAs (78% identity). Analysis of phylogenetic relationships between these and other available human and mouse CA isozyme sequences revealed that mammalian CA VB evolved much more slowly than CA VA, accepting amino acid substitutions at least 4.5 times more slowly since each evolved from its respective human–mouse ancestral gene around 90 million years ago. Both the differences in tissue distribution and the much greater evolutionary constraints on CA VB sequences suggest that CA VB and CA VA have evolved to assume different physiological roles.

Notes for a memorial (fragment), [ca. 1829]

Fragment of notes referencing the Harvard President's third plan for the library catalogue.

XI. Catalogue of Harvard graduates, [ca. 1810]

This paper notebook contains a handwritten, alphabetical listing of graduates of the Harvard Classes of 1642 to 1809 presumably compiled from the published Triennial Catalogues.

II. Academic notebook, [ca. 1745]

This paper notebook contains undated and unattributed handwritten summaries and notes from published texts on world history, religion, and natural history, and was presumably kept by William Sever. The first page notes the death of poet Alexander Pope in 1744, constituting the latest date referenced in the notebook. The entries are typically short and offer condensed information on subjects including the histories of England, Japan and Siam; early Christian history; and natural religion.

Mathematics notebook, ca. 1714-1718, with chronology of the reign of Augustus

The first two pages of this notebook contain a comparative chronology of the reign of Augustus, outlined in two columns. One column outlines the chronology according to ecclesiastical scholar Laurence Echard, and the other column outlines the chronology according to William Cave. The rest of the notebook contains extensive entries on the following subjects, with related rules, problems, and illustrations: fractions, decimals, arithmetical progression, geometrical progression, "disjunct proportion, or ye Golden Rule," signs and symbols, integers, geometrical definitions, and Euclidian geometry.

A Chaldee grammar, founded upon the writings of Daniel and Ezra, ca. 1776

This manuscript grammar notebook, written in Chaldean Aramaic and English, appears to have originally belonged to William Bentley (Harvard A.B. 1777); Bentley's name and a date, "December 1776," appear on the volume but have been struck through, and the handwriting appears to be his. The names of Elisha Parmele and Polly Parmele are also on the volume; presumably it was given to Elisha by Bentley, and upon Elisha's death in 1784 it was passed to Polly.

[Letter from William Allen to the Corporation of Harvard College], 1806 April 29

Letter requesting a proctor for the west end of Massachusetts Hall.

"A list of books borrowed from the former Library & not yet return'd," ca. 1764

Lists books borrowed by many individuals, including Governor William Shirley, Colonel Brinley, General Brattle, Secretary Willard, Judge Danforth, Colonel Wendell, Thomas Oliver, Christ Bridge Marsh, and Francis Foxcroft. Entries include the author and title of the borrowed volumes.

Lists of books donated by individuals and organizations in Scotland, ca. 1766 (3 manuscript copies)

These lists include books donated by Anthony Ferguson, an Aberdeen merchant; the Society for Promoting Religious Knowledge; William Gray, bookseller; Mr. Hog, merchant; Messrs. Gray and Alston, printers; Mr. Miller, bookseller; John Erskine, who donated his own work, Theological Dissertations; the Reverend Mr. Randal; and the Reverend Walter Scot Baxter. The lists are almost identical, though there are several variations and discrepancies.