Coutumes des pays et comté de Flandre. Quartier d'Ypres.

v.1. Coutume de la ville d'Ypres.--v.2 Sources et développement de la coutume d'Ypres.

Coutumes du pays et comté de Hainaut,

Introduction with bibliography, by J. Delacourt, pub. with special t.-p. 1883, is prefixed to v.1.

Coutumes du comté de Looz, de la seeigneurie de Saint-Trond et du comté impérail de Reckheim,

Vol. 3 published by J. Goemaere.

Coutumes des pays et comté de Flandre. Quartier d'Ypres.

Mode of access: Internet.

Coutumes des pays et comté de Flandre. Quartier de Bruges. Coutumes des petites villes et seigneuries enclavées.

v.1. Ardenbourg. Biervliet. Blankenberghe.--v.2. Cadsant. Caprycke. Damme. Dixmunde. Eecloo.--v.3. Ghistellles. Houcke. Lichtervelde. Maldeghem. Merckem. Middelbourg. Mude. Munikerede. Nieuvliet. Oostbourg.--v.4. Ostende. Oudenbourg. Sluis.--v.5. Sysseele. Thourout. Watervliet.--v.6. Winendale. Ysendeke. Supplement.

Coutumes des pays et comté de Flandre. [Quartier de Gand]

Vol. 1 by A. E. Gheldolf; v. 2 by A. Du Bois and L. De Hondt; v. 3-6, 11 by Th. de Limburg-Stirum; v. 7-10, 14 by D. Berten.

Coutumes des pays, duché de Luxembourg et comté de Chiny,

Vol. 2 by Ch. Laurent.

Mémoires et documents inédits [in -8ö pour servir à l'histoire de la Franche-Comté

"Publiés par l'Académie de Besançon."

Lettres sur l'histoire médicale du nord-est de la France: Lorraine et Barrois, Province des Trois-Evêchés, Franche-Comté, Ardennes, Haute et Basse-Alsace, Duché de Luxembourg, Palatinat.

Mode of access: Internet.

Recherches sur le patois de Franche-Comté, de Lorraine et d'Alsace.

Mode of access: Internet.

Noblesse et chevalerie du comté de Flandre, d'Artois et de Pacardie /

Includes bibliographical references.

Les memoires historiques de la Repub. Sequanoise, et des Princes de la Franche-Comté de Bourgougne : auec un sommaire de l'Histoire des Catholiques Rois de Castille, & Portugal, de la maison desdicts Princes de Bourgougne ... /

CCBE S. XVI, G, 1147

Pulse Pressure magnifies the effect of COMT Val158Met on 15 Year Episodic Memory Trajectories

We investigated whether a physiological marker of cardiovascular health, pulse pressure (PP), and age magnified the effect of the functional COMT Val158Met (rs4680) polymorphism on 15-years cognitive trajectories [episodic memory (EM), visuospatial ability, and semantic memory] using data from 1585 non-demented adults from the Betula study. A multiple-group latent growth curve model was specified to gauge individual differences in change, and average trends therein. The allelic variants showed negligible differences across the cognitive markers in average trends. The older portion of the sample selectively age-magnified the effects of Val158Met on EM changes, resulting in greater decline in Val compared to homozygote Met carriers. This effect was attenuated by statistical control for PP. Further, PP moderated the effects of COMT on 15-years EM trajectories, resulting in greater decline in Val carriers, even after accounting for the confounding effects of sex, education, cardiovascular diseases (diabetes, stroke, and hypertension), and chronological age, controlled for practice gains. The effect was still present after excluding individuals with a history of cardiovascular diseases. The effects of cognitive change were not moderated by any other covariates. This report underscores the importance of addressing synergistic effects in normal cognitive aging, as the addition thereof may place healthy individuals at greater risk for memory decline.

The effects of gender and COMT Val158Met polymorphism on fearful facial affect recognition:a fMRI study

The functional catechol-O-methyltransferase (COMT Val108/158Met) polymorphism has been shown to have an impact on tasks of executive function, memory and attention and recently, tasks with an affective component. As oestrogen reduces COMT activity, we focused on the interaction between gender and COMT genotype on brain activations during an affective processing task. We used functional MRI (fMRI) to record brain activations from 74 healthy subjects who engaged in a facial affect recognition task; subjects viewed and identified fearful compared to neutral faces. There was no main effect of the COMT polymorphism, gender or genotypegender interaction on task performance. We found a significant effect of gender on brain activations in the left amygdala and right temporal pole, where females demonstrated increased activations over males. Within these regions, Val/Val carriers showed greater signal magnitude compared to Met/Met carriers, particularly in females. The COMT Val108/158Met polymorphism impacts on gender-related patterns of activation in limbic and paralimbic regions but the functional significance of any oestrogen-related COMT inhibition appears modest. Copyright © 2008 CINP.