Experimental analysis on the use of CCC systems to analyze the in-situ bearing capacity of C&D materials

Compaction is one of the most important processes in roadway construction. It is needed to achieve high quality and uniformity of pavement materials, which in turn better ensure long lasting performance.

Studio di una miscela in misto cementato con aggregati riciclati da C&D.

La ricerca, presentata in questa tesi di laurea, si pone quale obiettivo, quello di studiare le possibilità di impiego di materiali provenienti da attività da C&D, in sostituzione degli inerti vergini di cava, nella confezione dei misti cementati per strati di base e fondazioni stradali. Lo studio è stato condotto per conto della CEA (Cooperativa Edile Appennino S.c.a.r.l.) la quale ha fornito il materiale riciclato in due diverse curve granulometriche 0/20 e 0/30. Tutte le prove sono state eseguite presso il Laboratorio di Strade della Facoltà di Ingegneria dell’Università degli Studi di Bologna.

Allerunterthänigst-gründliche Gegen-Information Und Exceptiones Sub- & Obreptionis : An Die Römis. Kayserl. ... Majestät ... Auff das am 12. May nup. und 19. currentis mensis erlassene Kayserl. Rescript, Juncta Petitione Humillima Pro Clementissima cassatione ejusdem ... ; In Sachen Judenschafft zu Franckfurth am Mayn Contrà Den Magistrat daselbsten ; Bey höchst-preyßlichen Reichs-Hof-Rath Den 23. Julii 1714 übergeben ; Mit Beylagen A, B, C & D ; Das Bau-Weesen betreffend

Burgerschafftl. Abgeordneter [Johann Dieterich Notebohm ; Joachim Hoppe] [[Elektronische Ressource]]

c&d-learning implementation architecture: Adapting e-learning to developing countries

From the educational point of view, the most widespread method in developing countries is on-site education. Technical and economic resources cannot support conventional distance learning infrastructures and it is even worse for courses in universities. They usually suffer a lack of qualified faculty staff, especially in technical degrees. The literature suggest that e-learning is a suitable solution for this problem, but its methods are developed attending to educational necessities of the First World and cannot be applied directly to other contexts. The proposed methodology is a variant of traditional e-learning adapted to the needs of developing countries. E-learning for Cooperation and Development (c&d-learning) is oriented to be used for educational institutions without adequate technical or human resources. In this paper we describe the c&d-learning implementation architecture based on three main phases: hardware, communication and software; e.g. computer and technical equipping, internet accessing and e-learning platform adaptation. Proper adaptation of educational contents to c&d-learning is discussed and a real case of application in which the authors are involved is described: the Ngozi University at Burundi.

Factors impacting the market share of Construction and Demolition (C&D) Waste recycling solutions

Current EU Directives force the Member States to assure by 2020 that 70% of the Construction and Demolition (C&D) waste is recovered instead of landfilled. While some countries have largely achieved this target, others still have a long way to go. For better understanding the differences arising from local disparities, six factors related to technical, economic, legislative and environmental aspects have been identified as crucial influences in the market share of C&D waste recycling solutions. These factors are able to identify the causes that limit the recycling rate of a certain region. Moreover, progress towards an efficient waste management can vary through the improvement of a single factor. This study provides the background for further fine-tuning the factors and their combination into a mathematical model for assessing the market share of C&D recycling solutions.

Role of the Box C/D Motif in Localization of Small Nucleolar RNAs to Coiled Bodies and Nucleoli

Small nucleolar RNAs (snoRNAs) are a large family of eukaryotic RNAs that function within the nucleolus in the biogenesis of ribosomes. One major class of snoRNAs is the box C/D snoRNAs named for their conserved box C and box D sequence elements. We have investigated the involvement of cis-acting sequences and intranuclear structures in the localization of box C/D snoRNAs to the nucleolus by assaying the intranuclear distribution of fluorescently labeled U3, U8, and U14 snoRNAs injected into Xenopus oocyte nuclei. Analysis of an extensive panel of U3 RNA variants showed that the box C/D motif, comprised of box C′, box D, and the 3′ terminal stem of U3, is necessary and sufficient for the nucleolar localization of U3 snoRNA. Disruption of the elements of the box C/D motif of U8 and U14 snoRNAs also prevented nucleolar localization, indicating that all box C/D snoRNAs use a common nucleolar-targeting mechanism. Finally, we found that wild-type box C/D snoRNAs transiently associate with coiled bodies before they localize to nucleoli and that variant RNAs that lack an intact box C/D motif are detained within coiled bodies. These results suggest that coiled bodies play a role in the biogenesis and/or intranuclear transport of box C/D snoRNAs.

The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-alpha 4 integrin interaction.

Vascular cell adhesion molecule 1 (VCAM-1) represents a structurally and functionally distinct class of immunoglobulin superfamily molecules that bind leukocyte integrins and are involved in inflammatory and immune functions. X-ray crystallography defines the three-dimensional structure of the N-terminal two-domain fragment that participates in ligand binding. Residues in domain 1 important for ligand binding reside in the C-D loop, which projects markedly from one face of the molecule near the contact between domains 1 and 2. A cyclic peptide that mimics this loop inhibits binding of alpha 4 beta 1 integrin-bearing cells to VCAM-1. These data demonstrate how crystallographic structural information can be used to design a small molecule inhibitor of biological function.