Sterna, más que vela

[ES]El Sterna, velero de 26 metros capitaneado por el reconocido navegante oceánico y emprendedor Albert Bargués, es el único barco de nuestro país que ofrece viajes a vela por las grandes latitudes. A finales de octubre llega a Barcelona después de estar 5 meses para el Ártico. Albert y su equipo, junto con los grupos de viajeros que han embarcado en el Sterna este verano, han vivido experiencias irrepetibles y un acercamiento intenso a la naturaleza navegando por las Islas Svalbard, Isla del Hueso, Jan Mayen, costa este de Groenlandia …. La filosofía de Sterna se que “Todavía hay lugares en la tierra donde sólo se puede llegar desde el mar”. Con este principio, se navega por destinos poco habituales y remotos donde predomina el valor ambiental y el descubrimiento. Es un proyecto empresarial nacido en nuestro país y que, entre otras cosas, ha sido elegido por distintas entidades e iniciativas, como una de las empresas más innovadoras del momento invitándola a participar en diversos eventos (Salón Internacional del Turismo de Cataluña 2014 en Innovation Zone, Exposición Ayer, hoy y mañana Cataluña Emprende…). La voluntad de los fundadores de Sterna se aportar un valor ambiental y social a través de su actividad. Por eso el barco y sus navegaciones están disponibles para llevar a cabo proyectos de investigación y de divulgación del conocimiento. Entre las colaboraciones de Sterna de esta primera campaña en el ártico han salido una serie de publicaciones periódicas en la sección El Viajero de El País digital y un documental, en edición en estos momentos, “Latitud 80º” que ya ha sido presentado en foros internacionales del sector www.goroka.tv/portfolio/latitud-80-sterna/.

Jan Floris de Jongh (1910 – 1988), President of IASSW 1954-1961

Jan Floris de Jongh played an undoubtedly significant role in the development of social work within and beyond The Netherlands. Yet, he and his contributions to the field are barely known, particularly in The Netherlands. His achievements warrant much more attention given that this Dutchman was also one of the most relevant figures in the international social work community.

CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells

In contrast to naive lymphocytes, memory/effector lymphocytes can access nonlymphoid effector sites and display restricted, often tissue-selective, migration behavior. The cutaneous lymphocyte-associated antigen (CLA) defines a subset of circulating memory T cells that selectively localize in cutaneous sites mediated in part by the interaction of CLA with its vascular ligand E-selectin. Here, we report the identification and characterization of a CC chemokine, cutaneous T cell-attracting chemokine (CTACK). Both human and mouse CTACK are detected only in skin by Southern and Northern blot analyses. Specifically, CTACK message is found in the mouse epidermis and in human keratinocytes, and anti-CTACK mAbs predominantly stain the epithelium. Finally, CTACK selectively attracts CLA+ memory T cells. Taken together, these results suggest an important role for CTACK in recruitment of CLA+ T cells to cutaneous sites. CTACK is predominantly expressed in the skin and selectively attracts a tissue-specific subpopulation of memory lymphocytes.

Identification of a novel selD homolog from Eukaryotes, Bacteria, and Archaea: Is there an autoregulatory mechanism in selenocysteine metabolism?

Escherichia coli selenophosphate synthetase (SPS, the selD gene product) catalyzes the production of monoselenophosphate, the selenium donor compound required for synthesis of selenocysteine (Sec) and seleno-tRNAs. We report the molecular cloning of human and mouse homologs of the selD gene, designated Sps2, which contains an in-frame TGA codon at a site corresponding to the enzyme’s putative active site. These sequences allow the identification of selD gene homologs in the genomes of the bacterium Haemophilus influenzae and the archaeon Methanococcus jannaschii, which had been previously misinterpreted due to their in-frame TGA codon. Sps2 mRNA levels are elevated in organs previously implicated in the synthesis of selenoproteins and in active sites of blood cell development. In addition, we show that Sps2 mRNA is up-regulated upon activation of T lymphocytes and have mapped the Sps2 gene to mouse chromosome 7. Using the mouse gene isolated from the hematopoietic cell line FDCPmixA4, we devised a construct for protein expression that results in the insertion of a FLAG tag sequence at the N terminus of the SPS2 protein. This strategy allowed us to document the readthrough of the in-frame TGA codon and the incorporation of 75Se into SPS2. These results suggest the existence of an autoregulatory mechanism involving the incorporation of Sec into SPS2 that might be relevant to blood cell biology. This mechanism is likely to have been present in ancient life forms and conserved in a variety of living organisms from all domains of life.

Samlede vaerker. Mindeudgave ...

8 portraits of the author (clipped from advertisement) mounted on p. [5] of v.1.