308 resultados para Agat-3613
Resumo:
In analysing the release of agricultural land to urban development, the urban fringe literature has not focused on whether farmers are able to relocate from the urban fringe to remoter rural areas. Through interviews with representatives from the poultry industry in two Australian states, this paper identifies that poultry farm relocation strategies are constrained by off-farm economic relations, the land-use planning system and financial considerations. Closely aligned to these constraints on relocation is the on-going process of poultry farm intensification, which is seen as presenting rising problems for land-use management around expanding metropolitan centres in Australia. Of particular concern is the potential for amenity complaints and associated land-use conflicts, which have not been comprehensively investigated. Recognising that existing environmental and land-use planning controls are ineffective in producing amicable solutions when conflict involving poultry farming is at its most intense, the paper calls for improvements to the regulatory system, including greater consideration for how the process of relocation can be encouraged. (c) 2005 Elsevier Ltd. All rights reserved.
Resumo:
The physical and emotional changes that occur in adolescence are part of the process of sexual maturity. These changes occur irrespective of ability and are often aligned with psychological and social factors. When the nature of a disability has an inherent limitation in social awareness, as is the case for individuals with autism, the achievement of personal sexual identity can become much more complex. Challenges in supporting individuals in this respect can be caused by the sensitive aspects of inappropriate behaviour, the abstract nature of teaching the topic, and the general reluctance on the part of parents and staff to discuss sexuality in individuals with disabilities. This article explores how a residential school addressed this gap. It provides details of how this need was met for seven students and the process undertaken to involve staff, parents and other stakeholders to establish ongoing support.
Resumo:
Social interaction and understanding in autistic spectrum disorder (ASD) are key areas of concern to practitioners and researchers alike. However, there is a relative lack of information about the skills and competencies of children and young people with ASD who access ordinary community facilities including mainstream education. In particular, contributions by parents and their children have been under-utilized. Using two structured questionnaires, 19 children with ASD reported difficulties with social skills including social engagement and temper management and also reported difficulties with social competence, affecting both friendships and peer relationships. Parents rated the children's social skill and competence as significantly worse than did the children themselves, but there was considerable agreement about the areas that were problematic. Using an informal measure to highlight their children's difficulties, parents raised issues relating to conversation skills, social emotional reciprocity and peer relationships. The implications for assessment and intervention are discussed.
Resumo:
Although the impact of autism spectrum disorders (ASDs) on the family is well recognized, the way mothers attempt to make sense of the diagnosis is largely unexplored. However, in other disabilities, attributions have been shown to predict a variety of outcomes including maternal wellbeing and engagement in treatment. Using Weiner's (198S) three-dimensional model, 16 mothers were interviewed to examine the nature and impact of their beliefs about their child's ASD using semi-structured interviews and measures of depression, parenting stress and expectations for their child's future. The findings suggested that mothers made a diverse and complex range of attributions that were consistent with Weiner's dimensions of locus of cause, stability and controllability. The nature of their attributions reflected particular difficulties associated with ASDs, such as uncertainties regarding cause and prognosis. Taking account of mothers' search for meaning will better enable professionals to support families following diagnosis.
Resumo:
Anxiety disorders are common among children and young people with Autism Spectrum Disorders (ASD). Despite growing knowledge about the prevalence, phenomenology and treatment of anxiety disorders, relatively little is understood about the nature and impact of anxiety in this group and little is known about autism-specific factors that may play a role in the increased prevalence of anxiety disorders. In this exploratory study, we report on a series of 5 focus groups with 17 parents of children and adolescents with ASD and anxiety. Across groups, parents gave strikingly similar descriptions of the triggers and behavioural signs associated with anxiety. Another consistent finding was that many parents reported that their children had great difficulty expressing their worries verbally and most showed their anxiety through changes in their behaviour. The impact of anxiety was reported to often be more substantial than the impact of ASD itself. The implications of the focus group findings are discussed in relation to existing literature.
Resumo:
One potential source of heterogeneity within autism spectrum conditions (ASC) is language development and ability. In 80 high-functioning male adults with ASC, we tested if variations in developmental and current structural language are associated with current neuroanatomy. Groups with and without language delay differed behaviorally in early social reciprocity, current language, but not current autistic features. Language delay was associated with larger total gray matter (GM) volume, smaller relative volume at bilateral insula, ventral basal ganglia, and right superior, middle, and polar temporal structures, and larger relative volume at pons and medulla oblongata in adulthood. Despite this heterogeneity, those with and without language delay showed significant commonality in morphometric features when contrasted with matched neurotypical individuals (n = 57). In ASC, better current language was associated with increased GM volume in bilateral temporal pole, superior temporal regions, dorsolateral fronto-parietal and cerebellar structures, and increased white matter volume in distributed frontal and insular regions. Furthermore, current language–neuroanatomy correlation patterns were similar across subgroups with or without language delay. High-functioning adult males with ASC show neuroanatomical variations associated with both developmental and current language characteristics. This underscores the importance of including both developmental and current language as specifiers for ASC, to help clarify heterogeneity.
Influence of nitric oxide during maturation on bovine oocyte meiosis and embryo development in vitro
Resumo:
The effect of s-nitroso-N-acetyl-1,1-penicillamine (SNAP, a nitric oxide donor) during in vitro maturation (IVM) on nuclear maturation and embryo development was investigated. The effect of increasing nitric oxide (NO) during prematuration or maturation, or both, on embryo development was also assessed. 10(-3) M SNAP nearly blocked oocytes reaching metaphase II (MII) (7%, P < 0.05) while 10(-5) M SNAP showed intermediate proportions (55%). For 10(-7) M SNAP and controls (without SNAP), MII percentages were similar (72% for both, P > 0.05), but superior to the other treatment groups (P < 0.05). Blastocyst development, however, was not affected (38% for all treatments, P < 0.05). TUNEL-positive cells in hatched blastocysts (Day 9) increased when IVM included 10(-5) M SNAP (8 v. 3 to 4 cells in the other treatments, P > 0.05), without affecting total cell numbers (240 to 291 cells, P > 0.05). When oocytes were prematured followed by IVM with or without 10(-7) M SNAP, during either culture period or both, blastocyst development was similar (26 to 40%, P > 0.05). When SNAP was included during both prematuration and IVM, the proportion of Day 9 hatched embryos increased (28% v. 14 to 19% in the other treatments, P < 0.05). Apoptotic cells, however, increased when SNAP was included (6 to 10 cells) in comparison to prematuration and maturation without SNAP (3 cells, P < 0.05). NO may be involved in meiotic progression and apoptosis during embryo development.
Resumo:
The production of a healthy cloned calf is dependent on a multitude of successful steps, including reprogramming mediated by the oocyte, the development of a functional placenta, adequate maternal-fetal interaction, the establishment of a physiological metabolic setting and the formation of a complete set of well-differentiated cells that will eventually result in well-characterised and fully competent tissues and organs. Although the efficiency of nuclear transfer has improved significantly since the first report of a somatic cell nuclear transfer-derived animal, there are many descriptions of anomalies concerning cloned calves leading to high perinatal morbidity and mortality. The present article discusses some our experience regarding perinatal and neonatal procedures for cloned Zebu cattle (B. indicus) that has led to improved survival rates in Nellore cloned calves following the application of such `labour-intensive technology`.
Resumo:
Implantatförankrad protetik har blivit ett vanligt behandlingsalternativ vid tandförlust.Tänder som förlorats på grund av karies, aplasi, trauma (olycksfall) eller parodontit (tandlossning) kan idag på många patienter ersättas med hjälp av implantat det vill säga en konstgjord tandrot av titan. Ett eller flera implantat opereras/installeras in i käkbenet och förses därefter med en krona, en bro eller en protes.Vävnaden runt implantatet kan drabbas av infektion på liknande sätt som vävnaden runt naturliga tänder och kallas då periimplantit. Detta är en reversibel inflammatorisk process i mjukvävnaden runt ett implantat med förlust av benvävnad.Syftet med studien var att beskriva förekomst av periimplantit hos patienter som erhållit implantat åren 2000-2001 vid Centrum Oral Rehabilitering, Parodontologi, samt förekomst av eventuella skillnader i periimplantit med avseende på rökvanor, kön och tidigare parodontal diagnos.Studien var en retrospektiv, beskrivande jämförande journalstudie.Totalt granskades 100 journaler, 80 journaler exkluderades då inte röntgenbilder togs tre år efter fixtur/implantat installation. Resultatet visade att 13 var kvinnor (65 %), 8 rökare (40 %) och 11 (55 %) personer hade remitterats för tidigare förekomst av parodontit.63 implantat installerades på 20 patienter. Periimplantit uppstod vid 8 implantat (13 %). Dessa implantat fanns hos 8 olika patienter, 5 var kvinnor, 5 rökare och 5 hade remitterats för parodontal diagnos. Något statistiskt samband kunde inte påvisas mellan förekomst av periimplantit och kön, rökvanor eller tidigare parodontal diagnos.Konklusionen: Förekomst av periimplantit under åren 2000-2001 var 13 %, vilket stämmer med tidigare studier.
Resumo:
Trata-se de uma pesquisa exploratório-descritiva, que busca analisar, a partir de pressupostos de Dejours (1993, 1994, 1997, 1999) a influência de fatores de prazer e sofrimento na construção do significado do trabalho presentes em indivíduos que optaram por aderir a um Programa de Demissão Voluntária - PDV. Os dados foram coletados junto a ex-funcionários do Banco do Brasil, através de entrevistas semiestruturadas. Para análise dos dados foi utilizada a metodologia da análise de conteúdo, na modalidade de análise temática. Os resultados são apresentados em dezoito categorias iniciais, seis categorias intermediárias e duas categorias finais: o desmonte do setor público e a mudança no significado do trabalho. A problemática parte do pressuposto de que, com os PDV, a situação de se deixar a organização da qual se fazia parte pode repercutir em oportunidades em outras áreas, seja como empregado, seja como empregador. Por outro lado, pode se refletir em ausência de perspectivas quanto ao futuro. Os resultados obtidos mostram que o PDV é um fator desencadeante de sofrimento, considerando que, após a adesão ao Programa, permanece para os exfuncionários uma condição de frustração e de conflitos pessoais em decorrência da forma como foi conduzida a implementação do Programa.
Resumo:
O trabalho analisa a viabilidade de implementação de uma política pública na Cidade do Rio de Janeiro que leve em conta a descentralização municipal na área de Cultura O Brasil entra no Terceiro Milênio realizando a Reforma do Estado com reflexões de ações que estão sendo veiculadas no mundo inteiro. O fortalecimento do poder local apresenta-se como facilitador para a implementação de políticas públicas. A dinamização de uma política na área de Cultura baseada na descentralização municipal, visando à geração de maior emprego e renda nos bairros cariocas contribuirá, significativamente, para a redução de problemas sociais no Rio de Janeiro. No que tange à área Cultural, são propostas iniciativas inovadores que contemplem a realidade brasileira, valorizem talentos, reduzam custos supérfluos, proporcionem o incremento contínuo de público e platéia, disseminem cultura e o acesso popular à mesma. Devem ser modelos que contemplem as demandas das categorias profissionais afetadas às áreas de Arte e Cultura porém, o direcionamento de recursos públicos deve visar ao aumento do nível das comunidades da Cidade do Rio de Janeiro. O desenvolvimento de novos talentos ¿ de cunho popular ou erudito ¿ conjugado com a valorização de produtos culturais do folclore brasileiro e da arte popular devem ser permanentes estratégias da Política Cultural na Cidade do Rio de Janeiro.
Resumo:
Segundo uma perspetiva crítica e baseando-se em autores como Papert), Jonassen, Toffler, Robinson, Facer e Christensen, o artigo aborda a incorporação de tecnologias potencialmente transformadoras na escola, tão transformadoras que algumas delas (as TIC, por exemplo) têm tido poder suficiente para operarem mudanças radicais na maneira como vivemos e até como nos representamos, e como essas tecnologias acabam invariavelmente ao serviço do desenvolvimento do currículo, sem que daí advenham mudanças qualitativas importantes, quer para escola, muito menos para o próprio currículo. No caso particular das TIC, o artigo discute também como as propostas inovadoras do seu uso como ferramentas de aprendizagem desvinculadas dos modelos curriculares a priori, one-fits-all, desenvolvidas nomeadamente ao longo dos anos setenta e oitenta do século XX, foram sendo inexoravelmente suplantadas pelo uso de TIC ao serviço da didática e, mais recentemente, como suporte de plataformas digitais de distribuição de conteúdos curriculares.
DOES Percoll (TM) GRADIENT CENTRIFUGATION CAUSE HYPERACTIVATION on CRYOPRESERVED BOVINE SPERMATOZOA?
Resumo:
Abnormal placental development is common in the bovine somatic cell nuclear transfer (SCNT)-derived fetus. In the present study, we characterised the expression of E-cadherin and beta-catenin, structural proteins of adherens junctions, in SCNT gestations as a model for impaired placentation. Cotyledonary tissues were separated from pregnant uteri of SCNT (n - 6) and control pregnancies (n - 8) obtained by artificial insemination. Samples were analysed by western blot, quantitative RT-PCR (qRT-PCR) and immunohistochemistry. Bovine trophectoderm cell lines derived from SCNT and control embryos were analysed to compare with the in utero condition. Although no differences in E-cadherin or beta-catenin mRNA abundance were observed in fetal tissues between the two groups, proteins encoded by these genes were markedly under-expressed in SCNT trophoblast cells. Immunohistochemistry revealed a different pattern of E-cadherin and total beta-catenin localisation in SCNT placentas compared with controls. No difference was observed in subcellular localisation of dephosphorylated active-beta-catenin protein in SCNT tissues compared with controls. However, qRT-PCR confirmed that the wingless (WNT)/beta-catenin signalling pathway target genes CCND1, CLDN1 and MSX1 were downregulated in SCNT placentas. No differences were detected between two groups of bovine trophectoderm cell lines. Our results suggest that impaired expression of E-cadherin and beta-catenin proteins, along with defective beta-catenin signalling during embryo attachment, specifically during placentation, is a molecular mechanism explaining insufficient placentation in the bovine SCNT-derived fetus.