Suuntaa ilmaisevat adverbiaalit, suhdesääntö ja käsin: "ikkunointiin" perustuva analyysi

Summary

Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study.

OBJECTIVE: Resistin is associated with inflammation and insulin resistance and exerts direct effects on myocardial cells including hypertrophy and altered contraction. We investigated the association of serum resistin concentrations with risk for incident heart failure (HF) in humans. METHODS AND RESULTS: We studied 2902 older persons without prevalent HF (age, 73.6+/-2.9 years; 48.1% men; 58.8% white) enrolled in the Health, Aging, and Body Composition (Health ABC) Study. Correlation between baseline serum resistin concentrations (20.3+/-10.0 ng/mL) and clinical variables, biochemistry panel, markers of inflammation and insulin resistance, adipocytokines, and measures of adiposity was weak (all rho <0.25). During a median follow-up of 9.4 years, 341 participants (11.8%) developed HF. Resistin was strongly associated with risk for incident HF in Cox proportional hazards models controlling for clinical variables, biomarkers, and measures of adiposity (HR, 1.15 per 10.0 ng/mL in adjusted model; 95% CI, 1.05 to 1.27; P=0.003). Results were comparable across sex, race, diabetes mellitus, and prevalent and incident coronary heart disease subgroups. In participants with available left ventricular ejection fraction at HF diagnosis (265 of 341; 77.7%), association of resistin with HF risk was comparable for cases with reduced versus preserved ejection fraction. CONCLUSIONS: Serum resistin concentrations are independently associated with risk for incident HF in older persons.

"Tärkeä seikka" ja "keskeinen kysymys" : Mitä korpuslingvistinen analyysi paljastaa lähisynonyymeistä

Summary: What can corpus-linguistic analysis reveal about near synonyms?

Läpimenoaika-analyysi suomalaisesta lainsäädäntötuotoksesta 1975-2002 : analyysi eduskuntakäsittelystä ja lakien vahvistamisaikataulusta

English summary: Lifetime analysis of Finnish legislative output 1975-2002: The Parliamentary process and the confirmation of legislation (s. 1191.)

Oikeudenkäyntikulut kannustimena : taloustieteellinen analyysi oikeudenkäyntikulujen korvausvelvollisuuden vaikutuksista

English summary: Legal costs as incentive: An economic analysis of cost-shifting (s. 192.)

Suomalaisen vanhuspolitiikan strategiset vaiheet 1950-luvulta 2000-luvulle - asiakirja-analyysi

Summary: Strategic stages of development of Finnish geriatric policies from the 1950s to the 2000s - documentary analysis