Véland le forgeron : dissertation sur une tradition du moyen age, avec les textes islandais, anlo-saxons, anglais, allemands, et français-romans qui la concernent /

Includes bibliographical references.

Mensaje del Presidente de la República, Claudio Williman, a la H. Asamblea General al inaugurarse el 1.er período de la XXIV legislatura, 15 de febrero de 1911.

Mode of access: Internet.

El desarrollo comunicativo en la relación familia y escuela. Estrategias de intervención para los ciclos 1 y 2 de la educación básica primaria en dos colegios distritales

Tesis (Maestría en Docencia). -- Universidad de la Salle. Facultad de Ciencias de la Educación. Maestría en Docencia, 2016

Biomimetic Scaffold with Aligned Microporosity Designed for Dentin Regeneration

Tooth loss is a common result of a variety of oral diseases due to physiological causes, trauma, genetic disorders, and aging and can lead to physical and mental suffering that markedly lowers the individual’s quality of life. Tooth is a complex organ that is composed of mineralized tissues and soft connective tissues. Dentin is the most voluminous tissue of the tooth and its formation (dentinogenesis) is a highly regulated process displaying several similarities with osteogenesis. In this study, gelatin, thermally denatured collagen, was used as a promising low-cost material to develop scaffolds for hard tissue engineering. We synthetized dentin-like scaffolds using gelatin biomineralized with magnesium-doped hydroxyapatite and blended it with alginate. With a controlled freeze-drying process and alginate cross-linking, it is possible to obtain scaffolds with microscopic aligned channels suitable for tissue engineering. 3D cell culture with mesenchymal stem cells showed the promising properties of the new scaffolds for tooth regeneration. In detail, the chemical–physical features of the scaffolds, mimicking those of natural tissue, facilitate the cell adhesion, and the porosity is suitable for long-term cell colonization and fine cell–material interactions.

Il vulcanismo esplosivo : l'isola Ferdinandea: eruzione del 1831 nel mar di Sicilia

Il contenuto di questo volume non vuole rappresentare un testo didattico per lo studio in generale della vulcanologia in quanto in esso si tratta unicamente quell’a-spetto della disciplina che riguarda il vulcanismo esplosivo. In tal senso l’autore ritiene che questo testo possa essere utile per gli studenti di Scienze Geologiche che, vivendo nelle aree vulcaniche italiane di età quaternaria ed anche attive, possano, da laureati, svolgere attività professionali mirate alla individuazione e definizione di Pericolosità, Vulnerabilità e Rischio Vulcanico. Trattare gli argomenti che seguono non è stato facile e forse si poteva, in alcuni casi, renderli più semplici, ma talvolta la semplicità non sempre è sinonimo di precisione; inoltre, per descrivere certi aspetti non quantitativi si è costretti ad utilizzare un linguaggio quanto più possibile “ad hoc”. L’autore ha svolto la propria attività di ricerca in aree vulcaniche, sia in Italia che all’estero. Le ricerche in Italia sono state da sempre concentrate nelle aree di vulcanismo attivo in cui l’attività del vulcanologo è finalizzata fondamentalmente alla definizione della Pericolosità Vulcanica supporto indispensabile per la definizione dell’aree a Rischio Vulcanico, intendendo per Rischio il prodotto della Pericolosità per il Danno in termini, questo, di numero di vite umane ovvero di valore monetario dei beni a rischio nell’area vulcanica attiva. Le ricerche svolte dall’autore in Africa Orientale (Etiopia e Somalia) e nello Yemen hanno contribuito ad assimilare i concetti di vulcanologia regionale, rappresentata dall’ampia diffusione del vulcanismo di plateau, variabile per spessore dai 1500 ai 3000 metri, fra i quali si inseriscono, nella depressione dell’Afar, catene vulcaniche inquadrabili, dal punto di vista geodinamico, come “oceaniche” alcune delle quali attive e che si sviluppano per decine/centinaia di chilometri. Nelle aree vulcaniche italiane le difficoltà che sorgono durante il rilevamento risiedono nella scarsa continuità di affioramenti, talvolta incompleti per la descrizione delle variazioni di facies piroclastiche, non disgiunta dalla fitta vegetazione ovvero ur banizzazione specialmente nelle aree di vulcanismo attivo. Il rilevamento vulcanologico richiede competenze e l’adozione di scale adatte a poter cartografare le variazioni di facies piroclastiche che, a differenza dalle assise sedimentarie, in un’area vulcanica possono essere diffuse arealmente soltanto per alcune centinaia di metri. I metodi di studio delle rocce piroclastiche sono del tutto simili a quelli che si usano per le rocce clastiche, cioè dall’analisi delle strutture e delle tessiture alla litologica fino a quella meccanica; su questi clasti inoltre le determinazioni della densità, della mineralogia e della geochimica (Elementi in tracce e Terre Rare), ottenute sulla frazione vetrosa, rappresentano parametri talvolta identificativi di un’area vulcanica sorgente. Non esistono testi nei quali venga descritto come si debba operare nelle aree vulcaniche per le quali l’unica certezza unificante è rappresentata dall’evidenza che, nelle sequenze stratigrafiche, il termine al top rappresenta quello più relativamente recente mentre quello alla base indica il termine relativo più vecchio. Quanto viene riportato in questo testo nasce dall’esperienza che è stata acquisita nel tempo attraverso una costante azione di rilevamento che rappresenta l’uni- ca sorgente di informazione che un vulcanologo deve ricavare attraverso un attento esame dei depositi vulcanici (dalla litologia alla mineralogia, alla tessitura, etc.) la cui distribuzione, talvolta, può assumere un carattere interegionale in Italia nell’ambito dell’Olocene. Soltanto l’esperienza acquisita con il rilevamento produce, in un’area di vulcanismo attivo, risultati positivi per la definizione della Pericolosità, sapendo però che le aree vulcaniche italiane presentano caratteristiche ampiamente differenti e di conseguenza il modo di operare non può essere sempre lo stesso. Un esempio? Immaginate di eseguire un rilevamento vulcanico prima al Somma-Vesuvio e poi nei Campi Flegrei: sono mondi completamente differenti. L’autore desidera ribadire che questo testo si basa sulla esperienza acquisita sia come geologo sia come docente di Vulcanologia; pertanto il libro potrà forse risultare più o meno bilanciato, in forza dell’argomento trattato, in quanto durante l’attività di ricerca l’autore, come tutti, ha affrontato alcuni argomenti più di altri. Questo approccio può essere considerato valido per chiunque voglia scrivere un libro in maniera autonoma e originale, non limitandosi, come molte volte avviene, a tradurre in italiano un libro su tematiche analoghe diffuso, ad esempio, nel mondo anglosassone.Diversamente, si sarebbe potuto concepire un libro come un collage di capitoli scritti da vari autori, che magari avevano esperienza più specifica nei singoli argomenti, ma in tal senso si sarebbe snaturato lo spirito con cui si è impostato il progetto. L’autore, infine, ha fatto ricorso al contributo di altri autorevoli colleghi solo per temi importantissimi, ma in qualche modo complementari rispetto al corpus costitutivo del Vulcanismo Esplosivo.

Studio geologico del comprensorio Centane-Via Panoramica (Isola di Procida, Golfo di Napoli)

E' stato eseguito uno studio geologico del comprensorio Centane-Panoramica (Isola di Procida, Golfo di Napoli) finalizzato alla determinazione delle caratteristiche tecniche dei terreni e della granulometria nelle aree lato mare che caratterizzano la falesia costiera tufacea tra Punta Pizzaco e Punta Solchiaro. Sono state eseguite prove penetrometriche dinamiche i cui risultati sono stati elaborati unitamente alle curve granulometriche dei terreni. I risultati ottenuti hanno consentito di definire il grado di dissesto geomorfologico e la natura dei terreni in aree sub-pianeggianti poste alla sommità della falesia costiera.

Geophysics: Principles, applications and emerging technologies

This book presents research in the field of Geophysics, particularly referring to principles, applications and emerging technologies. Table of Contents: Preface pp. i-xxi Environmental Geophysics: Techniques, advantages and limitations (Pantelis Soupios and Eleni Kokinou, Department of Environmental and Natural Resources Engineering, Technological Educational Institute of Crete, Dynamics of the Ocean Floor, Helmholtz Centre for Ocean Research Kiel, Geomar)pp i-xxi Application of Innovative Geophysical Techniques in Coastal Areas (V. Di Fiore, M. Punzo, D. Tarallo, and G. Cavuoto, Institute for Marine Coastal Environment, National Research Council, Naples)pp. i-xxi Marine Geophysics of the Naples Bay (Southern Tyrrhenian sea, Italy): Principles, Applications and Emerging Technologies (Gemma Aiello and Ennio Marsella, Institute for Marine Coastal Environment, National Research Council, Naples)pp. i-xxi Oceanic Oscillation Phenomena: Relation to Synchronization and Stochastic Resonance (Shinya Shimokawa and Tomonori Matsuura, National Research Institute for Earth Science and Disaster Prevention, Univ. of Toyama)pp. i-xxi Assessment of ocean variability in the Sicily Channel from a numerical three-dimensional model using EOFs decomposition (R. Sorgente, A. Olita, A.F. Drago, A. Ribotti, L. Fazioli, and C. Tedesco, Institute for Marine Coastal Environment, National Research Council, Oristano)pp. i-xxi Monitoring Test of Crack Opening in Volcanic Tuff (Coroglio Cliff. Italy) Using Distributed Optical Fiber Sensor (A. Minardo, A. Coscetta, M. Caccavale, G. Esposito, F. Matano, M. Sacchi, R. Somma, G. Zeni, and L. Zeni, Department of Industrial and Information Eng., Second University of Naples Aversa, Institute for Marine Coastal Environment, National Research Council Naples, National Institute for Geophysics and Volcanology, Osservatorio Vesuviano Naples, Institute for Electromagnetic Sensing of the Environment, National Research Council Naples)pp. i-xxi

New morpho-bathymetric and tectono-stratigraphic data on Naples and Salerno gulfs (southern tyrrhenian sea, Italy) derived from bathymetric and seismic data analysis and integrated geological interpretation

New morpho-bathymetric and tectono-stratigraphic data on Naples and Salerno Gulfs, derived from bathymetric and seismic data analysis and integrated geologic interpretation are here presented. The CUBE(Combined Uncertainty Bathymetric Estimator) method has been applied to complex morphologies, such as the Capri continental slope and the related geological structures occurring in the Salerno Gulf.The bathymetric data analysis has been carried out for marine geological maps of the whole Campania continental margin at scales ranging from 1:25.000 to 1:10.000, including focused examples in Naples and Salerno Gulfs, Naples harbour, Capri and Ischia Islands and Salerno Valley. Seismic data analysis has allowed for the correlation of main morpho-structural lineaments recognized at a regional scale through multichannel profiles with morphological features cropping out at the sea bottom, evident from bathymetry.Main fault systems in the area have been represented on a tectonic sketch map, including the master fault located northwards to the Salerno Valley half graben. Some normal faults parallel to the master fault have been interpreted from the slope map derived from bathymetric data. A complex system of antithetic faults bound two morpho-structural highs located 20km to the south of the Capri Island. Some hints of compressional reactivation of normal faults in an extensional setting involving the whole Campania continental margin have been shown from seismic interpretation.

The Southern Ischia canyon system: examples of deep sea depositional systems on the continental slope off Campania (Italy)

The Southern Ischia canyon system has been investigated in detail through Multibeam bathymetry and Sparker seismic data and has been put in the geological framework of the deep sea depositional systems off the Campania region. The geological and geomorphological characteristics of the canyon system have been also compared with the characters of the Mediterranean submarine canyons and with the deep sea depositional systems of the Tyrrhenian sea. The Southern Ischia canyon system engraves a narrow continental shelf from Punta Imperatore to Punta San Pancrazio, being limited southwestwards from the relict volcanic edifice of the Ischia Bank. It consists of twenty-two drainage axes, whose planimetric trending has been reconstructed in a sketch morphological map realized through the geological interpretation of Multibeam bathymetry. While the eastern boundary of the canyon system is controlled by extensional tectonics, being limited by a NE-SW trending (anti-Apenninic) normal fault, its western boundary is controlled by volcanism, due to the growth of the Ischia volcanic bank. Submarine gravitational instabilities also acted in relationships to the canyon system, allowing for the individuation of large-scale creeping at the sea bottom and hummocky deposits already interpreted as debris avalanche deposits. Quaternary marine seismic sequences have been reconstructed through a densely spaced seismic grid recorded through a Sparker multitip seismic source, allowing for a detailed observation of steep erosional slopes occurring on the southern flank of the island and related deep sea depositional systems. Important implications of this study will regard the coastal monitoring and beach nourishment of the southern flank of the island, being involved by a strong erosion of marine and coastal systems.

Interactions between Late Quaternary volcanic and sedimentary processes in the Naples Bay, Southern Tyrrhenian sea

The interactions between Late Quaternary volcanic and sedimentary processes in the Naples Bay, Southern Tyrrhenian sea, are here discussed through the results of the marine geological survey at the scale 1:25.000. The example of the geological map n. 465 “Isola di Procida”, herein presented, has put in evidence the stratigraphy of marine Quaternary deposits and related volcanic seismic units. The volcanic deposits cropping out in the Procida island have been explained as the result of eruptions of local eruptive centres. The geological survey carried out onshore indicates the occurrence of several pyroclastic units linked to the eruptive activity of the Ischian and Phlegrean volcanic complexes, interstratified with the products erupted by local volcanic centres. The occurrence in the pyroclastic sequences of Ischia and Procida islands of several marker horizons and their stratigraphic correlations have allowed to reconstruct the volcanological evolution of the two islands and the interactions with sedimentary processes at the scale of the whole Tyrrhenian margin. Four geological maps at the scale 1:25.000 covering the whole Naples Bay have been reconstructed based on the interpretation of marine geological and geophysical data. The stratigraphic relationships between the seismic units and the eruptive deposits have testified the activity of several monogenetic volcanic centers, whose products are interstratified with marine and continental deposits of the Late Quaternary depositional sequence.

Stratigraphic Architecture of Deep Sea Depositional Systems in the Southern Tyrrhenian Sea: Some Examples in the Ischia and Stromboli Volcanic Islands (Southern Italy)

The stratigraphic architecture of deep sea depositional systems has been discussed in detail. Some examples in Ischia and Stromboli volcanic islands (Southern Tyrrhenian sea, Italy) are here shown and discussed. The submarine slope and base of slope depositional systems represent a major component of marine and lacustrine basin fills, constituting primary targets for hydrocarbon exploration and development. The slope systems are characterized by seven seismic facies building blocks, including the turbiditic channel fills, the turbidite lobes, the sheet turbidites, the slide, slump and debris flow sheets, lobes and tongues, the fine-grained turbidite fills and sheets, the contourite drifts and finally, the hemipelagic drapes and fills. Sparker profiles offshore Ischia are presented. New seismo-stratigraphic evidence on buried volcanic structures and overlying Quaternary deposits of the eastern offshore of the Ischia Island are here discussed to highlight the implications on marine geophysics and volcanology. Regional seismic sections in the Ischia offshore across buried volcanic structures and debris avalanche and debris flow deposits are here presented and discussed. Deep sea depositional systems in the Ischia Island are well developed in correspondence to the Southern Ischia canyon system. The canyon system engraves a narrow continental shelf from Punta Imperatore to Punta San Pancrazio, being limited southwestwards from the relict volcanic edifice of the Ischia bank. While the eastern boundary of the canyon system is controlled by extensional tectonics, being limited from a NE-SW trending (counter-Apenninic) normal fault, its western boundary is controlled by volcanism, due to the growth of the Ischia volcanic bank. Submarine gravitational instabilities also acted in relationships to the canyon system, allowing for the individuation of large scale creeping at the sea bottom and hummocky deposits already interpreted as debris avalanche deposits. High resolution seismic data (Subbottom Chirp) coupled to high resolution Multibeam bathymetry collected in the frame of the Stromboli geophysical experiment aimed at recording seismic active data and tomography of the Stromboli Island are here presented. A new detailed swath bathymetry of Stromboli Island is here shown and discussed to reconstruct an up-to-date morpho-bathymetry and marine geology of the area, compared to volcanologic setting of the Aeolian volcanic complex. The Stromboli DEM gives information about the submerged structure of the volcano, particularly about the volcano-tectonic and gravitational processes involving the submarine flanks of the edifice. Several seismic units have been identified around the volcanic edifice and interpreted as volcanic acoustic basement pertaining to the volcano and overlying slide chaotic bodies emplaced during its complex volcano-tectonic evolution. They are related to the eruptive activity of Stromboli, mainly poliphasic and to regional geological processes involving the geology of the Aeolian Arc.

Rapporto tecnico sulla ottimizzazione del processo di biosintesi di una Green Fluorescent Protein ricombinante estratta da A. sulcata

L’espressione di geni eterologhi in Escherichia coli rappresenta uno dei metodi più veloci, semplici ed economici per la produzione di ampie quantità di proteine target. Tuttavia, meccanismi di folding e le modifiche post traduzionali inducono a volte un non corretto ripiegamento delle proteine nella conformazione nativa, con successiva aggregazione in quelli che vengono definiti corpi di inclusione. Nel nostro caso, l’attenzione è stata focalizzata su una Green Fluorescent Protein (GFP) di 228 aa estratta da Anemonia sulcata, contenente un fluoroforo composto da tre amminoacidi Gln63, Tyr64, Gly65 all'interno di una struttura a barile. Il corretto folding della proteina era correlato strettamente alla funzionalità del fluoroforo. Il nostro obiettivo è stato quello, quindi, di ottimizzare il processo di biosintesi della GFP espressa in E. coli, ovviando alla formazione di corpi di inclusione contenenti la proteina (non funzionale), definendo e standardizzando inoltre, le condizioni che consentivano di produrre la più alta percentuale di GFP correttamente ripiegata (in condizioni non denaturanti) e quindi funzionale.

Technical Report on the reduced graphene oxide biosynthesis protocol for biological applications

The interest of scientific community on carbon-based smart materials is growing and, especially focus on graphene oxide (GO) and reduced graphene oxide (rGO). An increasing number of bio-applications such as biological applications as bacterial inhibition, drug delivery and photothermal therapy aims the use of GO and rGO. For this reason, the methods used for the synthesis of graphene materials are more important because same of those procedures imply chemical reactions that involve hazardous and toxic reagents. In fact, the biocompatibility and toxicological activity of graphene-related materials is related to the methodologies employed for the synthesis that determine the carbon/oxygen (C/O) ratio of graphene oxide species. In this technical report, we focused on the synthesis of GO by means of that lead to a biocompatible GO form with a lower oxygen content. Thus, the synthesis of rAsGFP-rGO with the green fluorescent protein allowed us to obtain a biocompatible materials, without using hazardous and toxic reagents. This biocompatibility is the most important prerogative for the use of GO in biological activity assays as reported in several publications.

An Unusual Case of Cerebral Oedema

Hereditary angioedema (HAE) is a rare genetic disorder transmitted as an autosomal dominant trait, characterized by reduced plasma concentration or by the presence of non-functional C1 esterase inhibitor. Oedema caused by HAE mostly affects the skin and bowel and can induce swelling of genitalia. Oedema can be life threatening if it causes swelling of the larynx with obstruction of the airways. We describe the case of a 52-year-old man who presented a neurological emergency (coma), where the remarkable localization of the clinical manifestation and the unusual symptomatology hindered the correct diagnosis.

Simultaneous Occurrence of Systemic Lupus Erythematosus, Rheumatoid Arthritis, Hashimoto’s Thyroiditis and Membranous Glomerulonephritis

Introduction: Membranous glomerulonephritis is commonly described in systemic lupus erythematosus (SLE) and hypothyroidism. Clinical presentation: We report a case of a 40-year-old woman who presented with a membranous glomerulonephritis associated with SLE, rheumatoid arthritis and hypothyroidism due to Hashimoto’s thyroiditis. Conclusions: The simultaneous occurrence of these three diseases as possible causes of membranous glomerulonephritis is extremely exceptional.