A comparison of estimated glomerular filtration rates using Cockcroft−Gault and the Chronic Kidney Disease Epidemiology Collaboration estimating equations in HIV infection

OBJECTIVES: The aim of this study was to determine whether the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)- or Cockcroft-Gault (CG)-based estimated glomerular filtration rates (eGFRs) performs better in the cohort setting for predicting moderate/advanced chronic kidney disease (CKD) or end-stage renal disease (ESRD). METHODS: A total of 9521 persons in the EuroSIDA study contributed 133 873 eGFRs. Poisson regression was used to model the incidence of moderate and advanced CKD (confirmed eGFR < 60 and < 30 mL/min/1.73 m(2) , respectively) or ESRD (fatal/nonfatal) using CG and CKD-EPI eGFRs. RESULTS: Of 133 873 eGFR values, the ratio of CG to CKD-EPI was ≥ 1.1 in 22 092 (16.5%) and the difference between them (CG minus CKD-EPI) was ≥ 10 mL/min/1.73 m(2) in 20 867 (15.6%). Differences between CKD-EPI and CG were much greater when CG was not standardized for body surface area (BSA). A total of 403 persons developed moderate CKD using CG [incidence 8.9/1000 person-years of follow-up (PYFU); 95% confidence interval (CI) 8.0-9.8] and 364 using CKD-EPI (incidence 7.3/1000 PYFU; 95% CI 6.5-8.0). CG-derived eGFRs were equal to CKD-EPI-derived eGFRs at predicting ESRD (n = 36) and death (n = 565), as measured by the Akaike information criterion. CG-based moderate and advanced CKDs were associated with ESRD [adjusted incidence rate ratio (aIRR) 7.17; 95% CI 2.65-19.36 and aIRR 23.46; 95% CI 8.54-64.48, respectively], as were CKD-EPI-based moderate and advanced CKDs (aIRR 12.41; 95% CI 4.74-32.51 and aIRR 12.44; 95% CI 4.83-32.03, respectively). CONCLUSIONS: Differences between eGFRs using CG adjusted for BSA or CKD-EPI were modest. In the absence of a gold standard, the two formulae predicted clinical outcomes with equal precision and can be used to estimate GFR in HIV-positive persons.

Hineh mah-tov u-mah-naʿim : Psalm 133 ; für Männerchor, Harmonium- und Pianoforte-Begleitung

componirt von Ed. Birnbaum

Bundeslied : [nach Psalm 133] ; für israelitische Cantoren

comp. ... von Adolph Schönfeld

Bundeslied : [nach Psalm 133]

comp. von A. Schönfeld

Ms. hebr. oct. 133 - [Sammelband in 6 Teilen: Handschriftenkonvolut]

Vorbesitzer: Abraham Merzbacher

Ms. Barth. 133 - Medizinische Sammelhandschrift

Vorbesitzer: Bartholomaeusstift Frankfurt am Main

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 364 - Streitigkeiten bei der Verlegung ihrer Bücher

u.a.: Buchhändler Johann David Sauerländer;

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 133 - Mitteilung über die Predigt zur Tierethik

u.a.: Parerga und Paralipomena; Tierethik; Anschaffung von Schopenhauers Veröffentlichungen in die Bibliothek Wiesbaden;

Ms. Praed. 133 - Sermones de sanctis

Vorbesitzer: Dominikanerkloster Frankfurt am Main

Ms.Ff.F.Stoltze 3. 133 - Brief von Otto Hörth an Lyda Stoltze

Stoltze: Biographie, Carl Rößler, Johannes Proelß, Verlag Keller

Na 1 Nachlass Max Horkheimer, 364 - Korrespondenzen mit Alexander Mitscherlich (p. V 124, 1-102a)

1 Brief von Alexander Mitscherlich an Georg August Zinn (Ministerpräsident), 1961; 9 Briefe zwischen Prof. Tobias Brocher und Max Horkheimer; beteiligt: Alexander Mitscherlich, 1964-1968;

Na 1 Nachlass Max Horkheimer, 504 - Korrespondenzen mit Theodor W. Adorno (p. VI 1B, 133 - 295)

Briefwechsel und Beilagen zwischen Max Horkheimer, Theodor W. Adorno und Gretel Adorno, 1942 - 1944; 1 Brief von Friedrich Pollock an Theodor W. Adorno, 1942; 1 Brief von Theodor W. Adorno an Friedrich Pollock, 1944; 1 Brief von Else Frenkel-Brunswick an Theodor W. Adorno, 1944; 1 Brief von Max Horkheimer an das American Jewish Commitee, 1944; Briefwechsel und Beilagen zwischen Gretel Adorno, Theodor W. Adorno und Frederick Wild, 1942 - 1944; 1 Brief von Gretel Adorno an Leo Löwenthal, 1944; 1 Brief von Monroe E. Deutsch an Theodor W. Adorno, 1944; Briefwechsel zwischen Theodor W. Adorno und Margot von Mendelssohn, 1942 - 1943; 1 Brief von der Bank of America in Los Angeles an Frederick Wild, 1942;

Ms. lat. oct. 133 - Psalterium non feriatum

Vorbesitzer: Freiherren von Holzhausen