Associação entre a concentração de selênio, o polimorfismo Pro198Leu da glutationa peroxidase 1 e a mortalidade em pacientes com choque séptico

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

As medidas de confiança no Conselho de Defesa Sul-americano (CDS): análise dos gastos em Defesa (2009-2012)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Meninas confinadas. Perfil das jovens em cumprimento de medida de internação em São Paulo e no Pará

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Tipos documentais e sua relação com o processo decisório de uma empresa hospitalar da região de Bauru/SP

Decisions are made constantly in organizational contexts; however, a wrong decision can bring undesirable consequences for organizations. In this sense, access to organic information becomes essential considering that decreases the uncertainties of managers in relation to decision making process. In this perspective, the identification of documental types from its production provides a consistent documental cycle, which will result in the recovery of information at the time requested by managers. Based on the above it was intended to verify what documental types recurrently used in the decision making process of a hospital company in the Bauru region, Sao Paulo State. For that, we applied the method 'Case Study' of Yin. We analyzed the information type that provided more security to the decision maker during the decision making. As a result, we elaborated a systematic documental organic types most used and most relevant to the decision-making process of the company, showing that when they are defined from the production of documents, the benefits for both the professional as archivist for the organization are significant.

Estratégias tecnológicas para aumento de solubilidade e diminuição de toxicidade do fármaco antifúngico anfotericina B

A Anfotericina B é o fármaco antifúngico referência desde a sua descoberta na década de 50 até os dias atuais para o tratamento de infecções fúngicas sistêmicas. O objetivo do trabalho é realizar uma revisão bibliográfica que forneça os sistemas de liberação comercializados e os que estão em estudo, focando estratégias tecnológicas que possam servir para resolver os problemas da baixa solubilidade em água e da alta nefrotoxicidade da Anfotericina B. A AmB é um fármaco que apresenta inexpressiva solubilidade em meio-aquoso, principalmente na região de pH dos fluídos biológicos (7,4–8,0), sendo administrado atualmente por via endovenosa. Justificando a importância desse estudo para a área farmacêutica, novos sistemas de liberação que usem a via oral, aumentarão a adesão por crianças e idosos, além de aumentar o arsenal terapêutico e diminuir os gastos com hospitalizações. Por ter a sua utilidade clínica limitada em razão de sua alta toxicidade, tem-se buscado direcionar a AmB especificamente para o fungo ou pelo menos para o local da infecção, mantendo-se longe o fármaco das células hospedeiras. Para isso, se busca diferentes veículos que não o desoxicolato (Fungizone). Por fim, as formulações lipídicas mostram-se com maior eficácia e com menor toxicidade comparadas a Anfotericina B-desoxicolato, mas não fazem parte da rotina hospitalar em razão do seu alto custo

A atividade física na saúde mental: uma revisão de literatura

Ao longo da história, a doença mental passou por diversos períodos de críticas relações com a própria humanidade, exposta à vulnerabilidade dos mitos e pré-concepções que motivaram a perseguição e segregação daqueles seres humanos qualificados como “insanos”. No Brasil, as primeiras intervenções específicas de atendimento à doença mental só ocorreram a partir da segunda metade do século 19. Atualmente a doença mental representa um dos maiores gastos da rede do SUS (Sistema Único de Saúde) (Ministério da Saúde do Brasil, 1999). Nas últimas décadas, a fim de diminuir o tempo de internação e o gasto com medicamentos, um conjunto de iniciativas surgiu como forma de transformar a compreensão cultural e a relação da sociedade com as pessoas que apresentam transtornos mentais. Dentre as novas propostas humanizadoras de atendimento, a educação física e, particularmente, o exercício, vieram mostrar sua contribuição nessa área. Para Silva (1995), a atividade física acarreta uma complexa rede de reações bioenergéticas no organismo e essas acabam por melhorar o rendimento físico e mental dos pacientes nas atividades de vida diária. Tendo em vista a relevância da intervenção através da atividade física no campo da doença mental, o objetivo deste trabalho foi analisar resultados dos estudos que demonstraram os benefícios da atividade física para indivíduos com transtornos psiquiátricos, considerando os aspectos fisiológicos e emocionais dos mesmos, através de revisão da literatura científica. Para isso, foi feito um levantamento nas principais bases de dados através do cruzamento de palavras chaves, tais como “saúde mental e atividade física”, “doença mental e atividade física”, “esquizofrenia e atividade física”, “transtorno psiquiátrico e atividade física”, “transtorno bipolar e atividade física”. Os resultados dos estudos revelaram que a atividade física possui...

Depressão e apoio social percebido por mães de crianças hospitalizadas

This study was performed as a requirement of the final course in Nursing. The study is cross-cutting, in order to identify associations between socioeconomic factors, education, child hospitalization in the ICU or not, degree of depression and level of social support (material, affective, emotional, informational and positive social interaction) and how to identify subgroups of mother - child vulnerable. Constitute themselves as subjects, mothers of children 0 to 17 years, 11 months and 29 days in hospital after the second day of hospitalization in the pediatric unit of a State Hospital Interior Paulista. Data collection was initiated after obtaining the assent of the Research Ethics Committee, as well as signing the consent form. We used the following instruments to collect data: the data form for socioeconomic and hospitalization; Beck Depression Inventory and Medical Outcomes Study (MOS). We obtained the result that there is a strong association between availability and social support and income per capita and the degree of depression, but did not find an association between time and hospital stay and whether the child was admitted to the ICU or not. We conclude that it is necessary to establish treatment services from the patient’s family, plus an appropriate social service support to meet this big demand for mothers who need support

Readequação acessível em edifício hospitalar em Ribeirão Branco/SP: (proposta de readequação espacial do Hospital Municipal Maria Rosa Cardoso)

Um dos problemas enfrentados pelas cidades brasileiras, e que atinge inclusive as de pequeno porte, refere-se à questão hospitalar. A falta de adequação de espaços e equipamentos tem causado grandes problemas à qualidade de vida da população. A melhoria das condições hospitalares nas cidades tem como consequência o aumento na qualidade de vida urbana; e esta, por sua vez está relacionada à adoção de medidas específicas a adequação hospitalar ás normas técnicas vigentes. O objetivo desse trabalho é realizar uma proposta projetual de requalificação espacial do Hospital Municipal de Ribeirão Branco (SP), incorporando uma visão sobre todos os aspectos necessários para o desenvolvimento correto de um programa hospitalar. Este trabalho de conclusão de curso visa dar condições confortáveis e autônomas de acesso a todos os usuários dessa unidade de saúde, além de melhor suas condições funcionais, em termos de programa hospitalar. Além disso, a proposta buscará inserir o Hospital num contexto tecnológico mais recente, para atualizar e potencializar a eficiência dos tratamentos

Infância, ludicidade e pedagogia hospitalar: encontros e desencontros nas práticas educativas

The aim of this study is to investigate the significance of educational practices aimed at children in non formal education, in this case, specifically, the hospital context. The chosen methodology is part of an investigation conducted in two phases. In the first phase was carried out a theoretical stage, scientifically based studies guided by an historical-cultural and Sociology of Childhood, enabling placement on the particularities of children, the playfulness and the positioning of Pedagogy in the hospital. After this theoretical study was performed the second phase, with the completion of an empirical study with a research and intervention in a hospital playroom, in a public hospital considered a regional center in the northwestern city of São Paulo. The methodological procedures adopted for this empirical study were participant observation, interviews, action research and a questionnaire. Participant observation and action research are conducted within the brinquetodeca in five meetings with about 15 children, interviews were conducted with three family members and the questionnaire was applied to a healthcare professional. Among the results we can mention the following findings: a confirmation of the necessity of work in the hospital directing playful adaptations for the preservation and development of children's learning, and recent publications are scarce about the Hospital Education and underscore the need for the professional practice of education in non-school, the educational activities carried out reveals the possibilities of offering the child the continuation of their educational activities involving the playful and educational, the international and national literature on educational practices in the hospital allow to check ...(Complete abstract click electronic access below)

Percepção da criança sobre a hospitalização

Regardless of their age, hospitalized children suffer from being separated from their mothers or their attachment figures. Hospitalization is a process that is difficult for children to cope with due to their separation from families, everyday environments and embedded disease scenarios. According to age, the intensity of such suffering is related to the development phase in which a child is found. The health care professionals that are close to children, not only as concerns care provision, but also emotionally, should be knowledgeable about the mother-child attachment. emotionally, should be knowledgeable about the mother-child attachment. To evaluate children’s perception of hospitalization. The study was conducted at the pediatric hospitalization unit of the Botucatu School of Medicine University Hospital – UNESP by means of interviews with hospitalized children aged 7 – 12 years and by using content analysis according to Bardin. Most of the interviewed children did not like the hospital environment and reported to miss their homes. From their statements, they showed their dissatisfaction in relation to pain and their submission to invasive procedures, which were the main complaints during the interviews. Our results agree with those found in the literature in relation to the hospital environment when the children reported the fact that they missed their homes as a difficulty to adapt. The analysis of results in this study and in previous ones led to the reflection on the importance of the presence of a relative during children’s hospitalization and the adaptation process. Despite their dissatisfaction in relation to invasive procedures, none of the children tried to stop the performance of tests and understood their importance. This is a characteristic of the operational phase, which comprises the development of perception of a whole situation and is when... (Complete abstract click electronic access below)

Gestão de gastos imprevistos no abastecimento de matéria-prima de uma fábrica

La performance desentreprises ça dépend, engrande partie, deses chaînesd’approvisionnement. Celas peuvent entretrès complexe, car elle implique tout le processus avant, pendant et après l’assemblage duproduit fini. Ce travaila donc comme objectifl’amélioration de lagestion des imprévus qu’arrivent audébutdela chaîne d’approvisionnement et lesimpacts sur l’approvisionnement de la ligne d’assemblage d’une usine. L’approche méthodologique utilisée est la recherche-action. De cette façon, ce travail présente une standardisation des processusquechaque département doit fairedans uncas de rupture dans la chaîne. D’après entretiens, analyses de document, standardisation des organigrammes et graphiques croisés dynamiques, ila été possible proposer un moyen plus critique d’analyser et résoudre certains problèmes. En tant que résultats, viennent un organigramme défini, une divulgation des informations plus précises pour la prise en décision et unes l’analyse critique de l’historique des imprévus. Il s’agit d’un ensemble des processus meilleur pour une bonne prise en décision de court, moyen et long terme pour les dépenses avec des imprévus dans l’approvisionnement de matière-première de l’usine

Acidentes na infância atendidos no pronto socorro de pediatria do Hospital das Clínicas de Botucatu que motivaram internação

Accidents represent a major public health problem as they are frequent, preventable, and account for high morbidity and mortality rates. Children are the most vulnerable to accidents due to their inherent characteristics, and as a result of their physical, sensorial, psychomotor and cognitive limitations, which will only develop with time. Watchfulness and careful attention are of paramount importance, especially as children develop locomotor skills that are accompanied by curiosity about their surroundings. Child accidents, particularly those that could have been avoided, are the accidents most commonly seen in emergency and urgency departments. Urgency and emergency departments are the greatest allies in the attention to pediatric accidents as they offer adequate, immediate and specific high complexity care to patients at risk, viewing their vital stabilization. Investigating the causes and consequences of this insult is essential to establish a diagnosis and to contribute for the adoption of measures of prevention, control, and assistance. To identify the epidemiologic characteristics of the accidents involving children that received care at the pediatric emergency department of Botucatu Medical School Hospital and required hospitalization. This quantitative, retrospective, descriptiveanalytic epidemiologic study included all children aged 0-14 years who had had an accident and were seen at the Pediatric Emergency Department of Botucatu Medical School Hospital of São Paulo State University/UNESP between January 1/2008 and December 31/2009. A total of 227 medical charts were reviewed and 178 (78.4%) patients were included in this study. Of these, 116 (65.1%) were males and 62 (34.8%) were females. Children aged 5 - 9 years (38.9%) were the most affected, followed by those aged 10 - 14 years (37.5%). Fractures occurred in 138 (77.5%) of the cases, followed by foreign bodies... (Complete abstract click electronic access below)

Proposta de um dispositivo para ajuste automático da altura de uma cama hospitalar

This paper proposes a mechanical device to adapt a simple model of hospital bed used in the Emergency Department at Santa Casa of Guaratinguetá, allowing the bed’s height adjustment with electromechanical drive. This adaptation aims to introduce improvements in the routine work of nurses and reduce ergonomic problems stemming from repetitive strain during the transfer of patients to stretchers and wheelchairs, as well as providing more comfort to the bedridden patient. The device is mainly composed of: an electric induction motor used to drive the engine, a steel spindle with square thread, which allows axial displacement of the bed, a transmission system with pulleys and belt, which transmits power supplied by the motor to the spindle. The mechanism allows the height of the bed is regulated between 400 and 800 mm. The estimated implementation cost of this proposal is lower than the acquisition cost of a commercial hospital bed with the same features, which confirms the feasibility of the proposed solution

Proposta de um dispositivo para adaptação em uma cama hospitalar para ajuste de altura

In hospitals, health professionals may face different situations and problems. By following them, it is remarkable that one of the difficulties is related to the support provided by the facilities to carry out their work. This also affects the quality of treatment offered to patients. One of the points of improvement that could be studied is hospital beds. The Fawler's simplest hospital bed type, used in most Brazilian public hospitals, is designed with an ergonomic average height that offers a default position for analysis and treatment of patients. There is no possibility of adjusting the height of those beds, and hence there is a limitation in this regard since that height is fixed, but the physical structures of the workers and patients may vary widely and there may be a conflict when there are people too large or small involved in this process. Beyond that, studies by experts show that beds with height adjustment decreases the muscular effort and improve the movement quality of the spine of nursing staff, reducing the force on certain vertebrae and also the ergonomic risk. Of course, patient comfort is also affected accordingly. As the beds made with height adjustment are very expensive, this study aims to design a device to adapt the not adjustable beds. The project must be viable from an economic and mechanic standpoint, being able to adapt both old and new simplest Fawler hospital bed models, since their dimensions are similar. The final result shows that it is possible to adapt such beds using the designed concept at a viable cost. Furthermore, this concept could be applied in other bed types or objects that have hollow feet

Incidência, fatores de risco e consequências de defeitos congênitos em recém-nascidos e natimortos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)