977 resultados para formulação multi-material ALE
Resumo:
It has been long stated that there are profound analogies between fracture experiments and earthquakes; however, few works attempt a complete characterization of the parallelisms between these so separate phenomena. We study the Acoustic Emission events produced during the compression of Vycor (SiO&sub&2&/sub&). The Gutenberg-Richter law, the modified Omori's law, and the law of aftershock productivity hold for a minimum of 5 decades, are independent of the compression rate, and keep stationary for all the duration of the experiments. The waiting-time distribution fulfills a unified scaling law with a power-law exponent close to 2.45 for long times, which is explained in terms of the temporal variations of the activity rate.
Resumo:
Os autores que analisam o conflito trabalho-família têm ressaltado a importância da busca do equilíbrio do tempo na dedicação para o trabalho sem que haja detrimento do tempo dedicado à família. Destacam-se três dimensões em que se podem encontrar conflitos entre o trabalho e a família: tempo, tensão e comportamento. Nesta pesquisa, tem-se como objetivo apresentar os conflitos trabalho-família percebidos por duas empresárias do setor de comércio de material de construção da cidade de Curitiba, bem como as ações dessas empresárias para lidarem com os conflitos identificados. Por meio de pesquisa qualitativa, do tipo estudo de multicasos, foram entrevistados tanto as empresárias quanto seus parceiros. Os achados da pesquisa corroboram os estudos citados na revisão teórica, sendo o fator tempo o mais frequentemente citado como gerador de conflitos trabalho-família e o controle emocional como a ação mais citada como atenuante desses mesmos conflitos.
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This work analyzes whether the relationship between risk and returns predicted by the Capital Asset Pricing Model (CAPM) is valid in the Brazilian stock market. The analysis is based on discrete wavelet decomposition on different time scales. This technique allows to analyze the relationship between different time horizons, since the short-term ones (2 to 4 days) up to the long-term ones (64 to 128 days). The results indicate that there is a negative or null relationship between systemic risk and returns for Brazil from 2004 to 2007. As the average excess return of a market portfolio in relation to a risk-free asset during that period was positive, it would be expected this relationship to be positive. That is, higher systematic risk should result in higher excess returns, which did not occur. Therefore, during that period, appropriate compensation for systemic risk was not observed in the Brazilian market. The scales that proved to be most significant to the risk-return relation were the first three, which corresponded to short-term time horizons. When treating differently, year-by-year, and consequently separating positive and negative premiums, some relevance is found, during some years, in the risk/return relation predicted by the CAPM. However, this pattern did not persist throughout the years. Therefore, there is not any evidence strong enough confirming that the asset pricing follows the model.
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The 2009-2010 Data Fusion Contest organized by the Data Fusion Technical Committee of the IEEE Geoscience and Remote Sensing Society was focused on the detection of flooded areas using multi-temporal and multi-modal images. Both high spatial resolution optical and synthetic aperture radar data were provided. The goal was not only to identify the best algorithms (in terms of accuracy), but also to investigate the further improvement derived from decision fusion. This paper presents the four awarded algorithms and the conclusions of the contest, investigating both supervised and unsupervised methods and the use of multi-modal data for flood detection. Interestingly, a simple unsupervised change detection method provided similar accuracy as supervised approaches, and a digital elevation model-based predictive method yielded a comparable projected change detection map without using post-event data.
Resumo:
The aim of this study was to extract multi-parametric measures characterizing different features of sit-to-stand (Si-St) and stand-to-sit (St-Si) transitions in older persons, using a single inertial sensor attached to the chest. Investigated parameters were transition's duration, range of trunk tilt, smoothness of transition pattern assessed by its fractal dimension, and trunk movement's dynamic described by local wavelet energy. A measurement protocol with a Si-St followed by a St-Si postural transition was performed by two groups of participants: the first group (N=79) included Frail Elderly subjects admitted to a post-acute rehabilitation facility and the second group (N=27) were healthy community-dwelling elderly persons. Subjects were also evaluated with Tinetti's POMA scale. Compared to Healthy Elderly persons, frail group at baseline had significantly longer Si-St (3.85±1.04 vs. 2.60±0.32, p=0.001) and St-Si (4.08±1.21 vs. 2.81±0.36, p=0.001) transition's duration. Frail older persons also had significantly decreased smoothness of Si-St transition pattern (1.36±0.07 vs. 1.21±0.05, p=0.001) and dynamic of trunk movement. Measurements after three weeks of rehabilitation in frail older persons showed that smoothness of transition pattern had the highest improvement effect size (0.4) and discriminative performance. These results demonstrate the potential interest of such parameters to distinguish older subjects with different functional and health conditions.
Resumo:
Com o objetivo de estudar aspectos da ocorrência de acidente do trabalho por material perfurocortante entre trabalhadores de enfermagem de um hospital universitário, foram entrevistados 46 trabalhadores que se acidentaram no período de junho a dezembro de 1994. Os resultados forneceram dados importantes que poderão subsidiar programas de prevenção.
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Este trabalho aborda a Unidade Centro de Material no contexto hospitalar, e os seus aspectos organizacionais, relacionados ao dimensionamento, zoneamento, recursos materiais e humanos.
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Realizou-se esta investigação, com os objetivos de identificar a ocorrência de acidentes de trabalho com material pérfuro-cortante potencialmente contaminado, entre enfermeiros e auxiliares de enfermagem de um Hospital de ensino geral do interior do Estado de São Paulo; relacionar a ocorrência destes acidentes com a categoria profissional e anos de trabalho na instituição; identificar o tipo de material pérfuro-cortante causador do acidente e identificar as condutas tomadas após o acidente, pelo acidentado. Para a coleta de dados, através de entrevista individual, utilizou-se um formulário estruturado onde registrava-se, a causa atribuída ao acidente, o período de atuação do profissional acidentado, o objeto causador, a conduta tomada após o acidente. Evidenciou-se que as Precauções Padrão ou as antigas Precauções Universais não são utilizadas como deveriam, conferindo portanto, risco à equipe de enfermagem. Considera-se que esta equipe necessita de orientações específicas através de educação continuada sobre o assunto.
Resumo:
Introduction: Mantle cell lymphoma (MCL) accounts for 6% of all B-cell lymphomas and remains incurable for most patients. Those who relapse after first line therapy or hematopoietic stem cell transplantation have a dismal prognosis with short response duration after salvage therapy. On a molecular level, MCL is characterised by the translocation t[11;14] leading to Cyclin D1 overexpression. Cyclin D1 is downstream of the mammalian target of rapamycin (mTOR) kinase and can be effectively blocked by mTOR inhibitors such as temsirolimus. We set out to define the single agent activity of the orally available mTOR inhibitor everolimus (RAD001) in a prospective, multi-centre trial in patients with relapsed or refractory MCL (NCT00516412). The study was performed in collaboration with the EU-MCL network. Methods: Eligible patients with histologically/cytologically confirmed relapsed (not more than 3 prior lines of systemic treatment) or refractory MCL received everolimus 10 mg orally daily on day 1 - 28 of each cycle (4 weeks) for 6 cycles or until disease progression. The primary endpoint was the best objective response with adverse reactions, time to progression (TTP), time to treatment failure, response duration and molecular response as secondary endpoints. A response rate of 10% was considered uninteresting and, conversely, promising if 30%. The required sample size was 35 pts using the Simon's optimal two-stage design with 90% power and 5% significance. Results: A total of 36 patients with 35 evaluable patients from 19 centers were enrolled between August 2007 and January 2010. The median age was 69.4 years (range 40.1 to 84.9 years), with 22 males and 13 females. Thirty patients presented with relapsed and 5 with refractory MCL with a median of two prior therapies. Treatment was generally well tolerated with anemia (11%), thrombocytopenia (11%), neutropenia (8%), diarrhea (3%) and fatigue (3%) being the most frequent complications of CTC grade III or higher. Eighteen patients received 6 or more cycles of everolimus treatment. The objective response rate was 20% (95% CI: 8-37%) with 2 CR, 5 PR, 17 SD, and 11 PD. At a median follow-up of 6 months, TTP was 5.45 months (95% CI: 2.8-8.2 months) for the entire population and 10.6 months for the 18 patients receiving 6 or more cycles of treatment. Conclusion: This study demonstrates that single agent everolimus 10 mg once daily orally is well tolerated. The null hypothesis of inactivity could be rejected indicating a moderate anti-lymphoma activity in relapsed/refractory MCL. Further studies of either everolimus in combination with chemotherapy or as single agent for maintenance treatment are warranted in MCL.
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Aquest projecte tracta sobre la implantació d'un sistema ERP per tal de gestionar una empresa dedicada a la producció i distribució de material odontològic. El que durem a terme en aquesta aplicació serà importar les dades de l'aplicació VolkSoft a la nova aplicació. La idea principal es buscar una aplicació que satisfaci les necessitats de l'aplicació VolkSoft i a continuació, importar les dades d'una aplicació a l'altra.