958 resultados para developing of processes


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Decreasing the accidents on highway and urban environments is the main motivation for the research and developing of driving assistance systems, also called ADAS (Advanced Driver Assistance Systems). In recent years, there are many applications of these systems in commercial vehicles: ABS systems, Cruise Control (CC), parking assistance and warning systems (including GPS), among others. However, the implementation of driving assistance systems on the steering wheel is more limited, because of their complexity and sensitivity. This paper is focused in the development, test and implementation of a driver assistance system for controlling the steering wheel in curve zones. This system is divided in two levels: an inner control loop which permits to execute the position and speed target, softening the action over the steering wheel, and a second control outer loop (controlling for fuzzy logic) that sends the reference to the inner loop according the environment and vehicle conditions. The tests have been done in different curves and speeds. The system has been proved in a commercial vehicle with satisfactory results.

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La Región Metropolitana de Madrid (RMM) ha sufrido una gran transformación urbana en el periodo 1985-2007, en el cual ha crecido la población, ha crecido fuertemente el cuerpo físico, pero sobre todo han crecido su coste y su consumo, lo que supone que se ha vuelto más insostenible. Para tratar de comprender esta evolución asimétrica se ensayan sucesivos modelos que tratan de explicar la transformación de la realidad a través de la articulación de las formas de poder y sus políticas asociadas dentro del contexto local-metropolitano. Si se compara la transformación urbana en el periodo 1985-2007 respecto a la registrada durante el desarrollismo previo al presente periodo democrático, se encuentran similitudes, como el amplio consumo de suelo, pero el modelo desarrollista se inscribe en otras lógicas y tiene otros parámetros de contexto y es congruente ya que las últimas décadas del Régimen Franquista se caracterizan por un importantísimo aumento poblacional que se correspondía con el fuerte crecimiento industrial de la RMM. Esa congruencia relativa se pierde en el periodo estudiado, a pesar de que en 1985, se aprueba el Plan General de Ordenación Urbana de Madrid centrado en la ciudad existente y con un crecimiento contenido, y que puede considerarse un modelo abortado. Tras numerosas transformaciones políticas, económicas, sociales y urbanísticas se llega a una situación opuesta a la prevista en el citado Plan. Más de veinte años después, en 2007, se presentan no solo síntomas de agotamiento del modelo finalmente adoptado, sino su quiebra dramática tanto en su dimensión inmobiliario-financiera como del espacio del bienestar. Es precisamente la supresión de los mecanismos de regulación lo que ha caracterizado la evolución de los modelos urbanos, en correspondencia con la desregulación de las actividades económicas y de los flujos de capital propios del modelo "neoliberal". La actual crisis financiera internacional, en especial en algunos países periféricos europeos como España, ha demostrado cómo las políticas económicas que se han llevado a cabo, fuera de toda regulación, han resultado insostenibles. Pero no se trata solo de una crisis económica. En el caso español, de todas las dimensiones de la crisis, destaca la dimensión urbana, o el auge y caída del ciclo inmobiliario, debido a la urbanización intensiva del territorio en relación con el circuito secundario de la acumulación capitalista, habiendo tenido especial incidencia en algunos territorios como la RMM. En la Región Metropolitana de Madrid la situación actual es de crisis urbana, causada principalmente por el divorcio entre las necesidades y la producción de ciudad, pues no se ha basado el crecimiento en la creación de nuevos hogares, u otras cuestiones demográficas, sino en la acumulación de capital a través del crecimiento de la ciudad. Además, dicho crecimiento está conformado por una expansión urbana descontrolada, con mayores requerimientos energéticos que el modelo compacto y complejo tradicional, lo que unido a la escala de los procesos, supone un sistema urbano progresivamente ineficiente. El caso de la RMM resulta paradigmático, ya que la región ha desempeñado un papel como laboratorio de nuevas formas de gobierno y planificación que han dado un mayor protagonismo al espacio, que ha entrado en las dinámicas centrales principalmente por el apoyo al crecimiento físico, a la vez que han confluido circunstancias específicas, como un nuevo impulso al centralismo, lo que ha potenciado ciertas políticas, como considerar la ciudad como motor de crecimiento económico y de competitividad en el concierto europeo y mundial de ciudades. El estudio del papel de la planificación y sus crisis en la sucesión de los modelos, muestra su función nuclear en la propia constitución de estos —es parte fundamental de su aparato de regulación— y su valor no solo para poder entender el periodo, sino para poder proyectar otro futuro urbano. Este enfoque conduce a establecer la relación del planeamiento con las diferentes crisis económicas en el periodo de estudio lo que permite diferenciar tres momentos de dicha relación: la planificación urbanística austera bajo la influencia de la crisis fordista, la salida de la crisis a través de la imposición de un modelo urbano basado en el sobreproducción de espacio urbano, y la entrada en una crisis inmobiliaria y de financiarización en relación a la adopción de un modelo multidimensionalmente insostenible. El análisis de este periodo es la base para apuntar perspectivas que permitan transformar el gobierno urbano hacia un modelo urbano más deseable, o mejor aún, otros futuros posibles, que se enmarcan dentro de la alternativa principal que supone la sostenibilidad. Madrid's Metropolitan Region (MMR) has undergone a major urban transformation in the period 1985-2007, where the population has grown up, the built environment has grown strongly, but mostly its cost and consumption have grown, which means that it has become unsustainable. To try to understand this evolution successive asymmetric models are tested in order to explain the transformation of reality through the articulation of forms of power and its associated policies in that localmetropolitan context. Comparing the urban transformation in the period 1985-2007 to the existing during developmentalism in the current predemocratic period, both have similarities in terms of land consumption, but the previous developmentalism model is part of another logics and has got other context parameters. It is consistent since the last decades of the Franco Regime was characterized by an important population increase that corresponded to strong industrial growth of the MMR. This relative consistency is lost during the study period, although in 1985, with the approval of the Master Plan of Madrid that was focused on the existing city, with a limited growth, and it may be considered an interrupted model. After numerous political, economic, social and urban changes, there is the opposite situation to that foresight under that Plan. Over twenty years later, in 2007, there are not only signs of exhaustion of the model which was finally adopted, but also its dramatic collapse in both real estate and financial dimension of space as well. The urban transformation under analysis has relaunched the hegemony of the sectors that rule the growth of the Madrid's Metropolitan Region and it is supported by decision making and financing of the different administrations with the passivity of the social stakeholders and citizens. This has meant the removal of regulatory mechanisms that have characterized the evolution of urban models, corresponding to the deregulation of economic activities and capital flows according to "neoliberal" model. The current international financial crisis, especially in some European peripheral countries like Spain, has shown how economic policies that have been carried out, without any regulation, have proven unsustainable. But it is not only an economic crisis. In the Spanish case, of all the dimensions of the crisis, it is the urban dimension that is highlighted, or the rise and fall of real estate cycle, due to intensive urbanization of the territory in relation to the secondary circuit of capital accumulation, having had a particular impact in some territories such as the Madrid's Metropolitan Region. In Madrid's Metropolitan Region there is the current situation of urban crisis, mainly caused by the divorce between needs and the city (space) production, because no growth has been based on creating new homes, or other demographic issues, but in the capital accumulation through growth of the city. Furthermore, this growth is made up of urban sprawl, with higher energy requirements than the traditional compact and complex one, which together with the scale of processes, is increasingly an inefficient urban system. The case of Madrid's Metropolitan Region is paradigmatic, since the region has played a role as a laboratory for new forms of governance and planning have given a greater role to space, which has entered the core dynamics supported mainly by physical growth, while specific circumstances have come together as a new impulse to centralization. This has promoted policies such as considering the city as an engine of economic growth and competitiveness in the international and the European hierarchy of cities. The study of the role of planning and crisis in the succession of models, shows its nuclear role in the constitution of these models is a fundamental part of its regulatory apparatus- and also its value not only to understand the period, but to anticipate to other urban future. This approach leads to establish the relationship of planning with the various crises in the study period, allowing three different moments of that relationship: the austere urban planning under the influence of Fordist crisis, the output of the crisis through imposition of an urban model based on the overproduction of urban space, and entry into a housing crisis and financialisation in relation to the adoption of a multi-dimensionally unsustainable model. The analysis of this period is the basis for targeting prospects that translate urban governance towards a more desirable urban model, or better yet, other possible futures, which are part of the main alternative that is sustainability.

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El objetivo de la presente Tesis está dirigido a analizar diversas opciones de diversificación que la pesca marítima profesional puede tener, poniendo el acento en el respeto al medio ambiente. En concreto la Pesca-turismo aparece como una de las alternativas más viables tanto por su respeto al medio ambiente como por su relativamente sencilla posibilidad de implantación en España. A fin de poder desarrollar la misma se proponen los cambios legislativos necesarios para su implantación en nuestro país procediéndose, para ello, al estudio de la situación actual de la actividad pesquera en nuestro país desde un punto de vista jurídico, con una especial consideración de la gestión y conservación de los recursos pesqueros. El estudio de su posible implantación en España, comienza analizando cuáles son las diferentes administraciones que influyen en dicha actividad y en qué medida lo hacen, tanto en el ámbito nacional como en el supranacional, con una especial referencia a la Unión Europea, así como la organización de las mismas. Acto seguido se procede al examen, tanto de la normativa sobre la materia, como de la jurisprudencia y la doctrina aplicables a la actividad de pesca marítima en España para, una vez llevado a cabo dicho estudio, comenzar con el examen de los requisitos exigidos, ya sean éstos de índole material o humana, a aquéllos que quieran llevarla a cabo. A continuación, se estudia el régimen de infracciones y sanciones, entrando, por último, en el terreno más propiamente de conservación de los recursos, donde se examinan las medidas que, a tal fin, se encuentran en nuestro ordenamiento jurídico. Más adelante se analiza, siquiera sea brevemente, la pesca deportiva, que, aunque con una incidencia muy inferior, no deja de ser otra forma de actividad extractiva. La existencia de otras experiencias parecidas a la propuesta de pesca-turismo en el ámbito internacional es objeto de estudio a fin de determinar cuál es la situación en otros países donde se hayan implantado con anterioridad. Para ello se lleva a cabo un análisis de las distintas soluciones que a este mismo problema se han dado en otros países también con amplia tradición en este campo procediendo, a tal fin, a un estudio de la legislación sobre la pesca-turismo, fundamentalmente en Italia, pero también en Francia y Portugal. A la vista de cuanto antecede es posible concluir que al día de hoy no es factible la realización de las actividades de Pesca-turismo con los instrumentos jurídicos de los que se dispone en España, dado que existen puntos sustanciales en los mismos que o bien impiden o bien no permiten su desarrollo. Por tanto el planteamiento de tales actividades necesariamente conlleva una serie de modificaciones normativas. El siguiente paso y en relación con las modificaciones normativas a efectuar, se ofrece un texto alternativo al texto legal a modificar (Ley 3/2001 de Pesca Marítima del Estado) y al Real Decreto 1027/1989, mientras que se dejan efectuados los apuntes precisos de cual debería de ser el marco reglamentario que, en desarrollo de las modificaciones anteriores, posibilitasen el ejercicio de la Pesca-turismo en España. Por último se ha optado por efectuar un análisis de la opinión del sector, tendente a verificar si los datos obtenidos empíricamente quedaban asimismo reflejados en las actitudes de los destinatarios finales de tales normas, que no serían otros que los pescadores profesionales. A tal fin se ha procedido a recoger las opiniones de diversos colectivos del sector, a través tanto de las cofradías de pescadores como de las Federaciones, acerca de las actividades de pesca-turismo, buscando la representación de todas las zonas geográficas. Fruto de tal investigación se ha llegado a la conclusión de que el desarrollo de las actividades propuesta de pescaturismo cuenta con una opinión favorable dentro del sector que, con una mayoría aplastante se manifestó a favor de desarrollar la posibilidad de ejercicio de la mismas. SUMMARY The objective of this thesis is aimed to analyze various options of diversification that commercial maritime fishing can have, with an emphasis on respect for the environment. Specifically, fishing-tourism appears as one of the most viable alternatives because of its environmental friendliness as well by its relatively simple possibility of implementation in Spain In order to develop it, it is proposed the necessary changes legislative for implementation in our country proceeding to study of the current situation of fisheries in our country from a legal perspective, with special consideration of the management and conservation of fisheries resources. The study of their possible implementation in Spain, begins by analyzing which are the different administrations that influence in that activity and to what extent they do, both at the national field as well at the supranational field, with special reference to the European Union and organization of thereof. Then proceeds to an examination, both of the relevant legislation as well as of the jurisprudence and doctrine applicable to maritime fishing in Spain for, once conducted this study, to begin with the consideration of the requirements, be they human or material, to those who want to carry out. Then studies the regime of offences and penalties, entering, finally, in the field conservation of resources, where discusses measures which, to this end, are in our legal system Later analyzes, even briefly, sport fishing, which, although with a much lower incidence, it is another form of extractive activity. The existence of other similar experiences to the proposal of fishing-tourism in the international arena is object of study in order to determine which is the situation in other countries where it has been implemented previously. For that it is carried out an analysis of the different solutions that to this same problem have been given in other countries with long tradition in this field, to proceed to study about legislation on fishing-tourism, fundamentally in Italy, but also in France and Portugal In view of the above it can be concluded that today is not feasible to implement the fishing-tourism activities with the legal instruments that are available in Spain, as there are substantial points which prevent them or not allows its development. Therefore the approach to such activities necessarily entails a series of normatives changes. The next step and in relation to normatives changes to do, it is offered an alternative text to the legal text to modify (Law 3/2001 of the State Marine Fisheries) and to the Royal Decree No. 1027 / 1989, while we leave made accurate notes about which ought be the reglamentary framework that, in developing of the above modifications, can be enable exercise of fishing-tourism in Spain. Finally, it is been opted to carry out an analysis of the opinion of the sector, aimed at verifying if data obtained empirically were also reflected in the attitudes of the final recipients of such standards, who would not be other than the professional fishermen. For this purpose it has been collected the opinions of various groups of the sector, through of fishermen's associations and federations, about of the activities of tourism-fishing, looking for the representation of all geographical areas. The result of such an investigation has concluded that the development of this proposed activities fishing-tourism has a positive opinion within the sector because an overwhelming majority was in favor of developing the possibility of exercise of the same.

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El trigo blando (Triticum aestivum ssp vulgare L., AABBDD, 2n=6x=42) presenta propiedades viscoélasticas únicas debidas a la presencia en la harina de las prolaminas: gluteninas y gliadinas. Ambos tipos de proteínas forman parte de la red de gluten. Basándose en la movilidad en SDS-PAGE, las gluteninas se clasifican en dos grupos: gluteninas de alto peso molecular (HMW-GS) y gluteninas de bajo peso molecular (LMW-GS). Los genes que codifican para las HMW-GS se encuentran en tres loci del grupo 1 de cromosomas: Glu-A1, Glu-B1 y Glu-D1. Cada locus codifica para uno o dos polipéptidos o subunidades. La variación alélica de las HMW-GS es el principal determinante de de la calidad harino-panadera y ha sido ampliamente estudiado tanto a nivel de proteína como de ADN. El conocimiento de estas proteínas ha contribuido sustancialmente al progreso de los programas de mejora para la calidad del trigo. Comparadas con las HMW-GS, las LMW-GS forman una familia proteica mucho más compleja. La mayoría de los genes LMW se localizan en el grupo 1 de cromosomas en tres loci: Glu-A3, Glu-B3 y Glu-D3 que se encuentran estrechamente ligados a los loci que codifican para gliadinas. El número de copias de estos genes ha sido estimado entre 10-40 en trigo hexaploide, pero el número exacto aún se desconoce debido a la ausencia de un método eficiente para diferenciar los miembros de esta familia multigénica. La nomenclatura de los alelos LMW-GS por electroforesis convencional es complicada, y diferentes autores asignan distintos alelos a la misma variedad lo que dificulta aún más el estudio de esta compleja familia. El uso de marcadores moleculares para la discriminación de genes LMW, aunque es una tarea dificil, puede ser muy útil para los programas de mejora. El objetivo de este trabajo ha sido profundizar en la relación entre las gluteninas y la calidad panadera y desarrollar marcadores moleculares que permitan ayudar en la correcta clasificación de HMW-GS y LMW-GS. Se han obtenido dos poblaciones de líneas avanzadas F4:6 a partir de los cruzamientos entre las variedades ‘Tigre’ x ‘Gazul’ y ‘Fiel’ x ‘Taber’, seleccionándose para los análisis de calidad las líneas homogéneas para HMW-GS, LMW-GS y gliadinas. La determinación alélica de HMW-GS se llevó a cabo por SDS-PAGE, y se complementó con análisis moleculares, desarrollándose un nuevo marcador de PCR para diferenciar entre las subunidades Bx7 y Bx7*del locus Glu-B1. Resumen 2 La determinación alélica para LMW-GS se llevó a cabo mediante SDS-PAGE siguiendo distintas nomenclaturas y utilizando variedades testigo para cada alelo. El resultado no fue concluyente para el locus Glu-B3, así que se recurrió a marcadores moleculares. El ADN de los parentales y de los testigos se amplificó usando cebadores diseñados en regiones conservadas de los genes LMW y fue posteriormente analizado mediante electroforesis capilar. Los patrones de amplificación obtenidos fueron comparados entre las distintas muestras y permitieron establecer una relación con los alelos de LMW-GS. Con este método se pudo aclarar la determinación alélica de este locus para los cuatro parentales La calidad de la harina fue testada mediante porcentaje de contenido en proteína, prueba de sedimentación (SDSS) y alveógrafo de Chopin (parámetros P, L, P/L y W). Los valores fueron analizados en relación a la composición en gluteninas. Las líneas del cruzamiento ‘Fiel’ x ‘Taber’ mostraron una clara influencia del locus Glu-A3 en la variación de los valores de SDSS. Las líneas que llevaban el nuevo alelo Glu-A3b’ presentaron valores significativamente mayores que los de las líneas con el alelo Glu-A3f. En las líneas procedentes del cruzamiento ‘Tigre ’x ‘Gazul’, los loci Glu-B1 y Glu-B3 loci mostraron ambos influencia en los parámetros de calidad. Los resultados indicaron que: para los valores de SDSS y P, las líneas con las HMW-GS Bx7OE+By8 fueron significativamente mejores que las líneas con Bx17+By18; y las líneas que llevaban el alelo Glu-B3ac presentaban valores de P significativamente superiores que las líneas con el alelo Glu-B3ad y significativamente menores para los valores de L . El análisis de los valores de calidad en relación a los fragmentos LMW amplificados, reveló un efecto significativo entre dos fragmentos (2-616 y 2-636) con los valores de P. La presencia del fragmento 2-636 estaba asociada a valores de P mayores. Estos fragmentos fueron clonados y secuenciados, confirmándose que correspondían a genes del locus Glu-B3. El estudio de la secuencia reveló que la diferencia entre ambos se hallaba en algunos SNPs y en una deleción de 21 nucleótidos que en la proteína correspondería a un InDel de un heptapéptido en la región repetida de la proteína. En este trabajo, la utilización de líneas que difieren en el locus Glu-B3 ha permitido el análisis de la influencia de este locus (el peor caracterizado hasta la fecha) en la calidad panadera. Además, se ha validado el uso de marcadores moleculares en la determinación alélica de las LMW-GS y su relación con la calidad panadera. Summary 3 Bread wheat (Triticum aestivum ssp vulgare L., AABBDD, 2n=6x=42) flour has unique dough viscoelastic properties conferred by prolamins: glutenins and gliadins. Both types of proteins are cross-linked to form gluten polymers. On the basis of their mobility in SDS-PAGE, glutenins can be classified in two groups: high molecular weight glutenins (HMW-GS) and low molecular weight glutenins (LMW-GS). Genes encoding HMW-GS are located on group 1 chromosomes in three loci: Glu-A1, Glu-B1 and Glu-D1, each one encoding two polypeptides, named subunits. Allelic variation of HMW-GS is the most important determinant for bread making quality, and has been exhaustively studied at protein and DNA level. The knowledge of these proteins has substantially contributed to genetic improvement of bread quality in breeding programs. Compared to HMW-GS, LMW-GS are a much more complex family. Most genes encoded LMW-GS are located on group 1 chromosomes. Glu-A3, Glu-B3 and Glu-D3 loci are closely linked to the gliadin loci. The total gene copy number has been estimated to vary from 10–40 in hexaploid wheat. However, the exact copy number of LMW-GS genes is still unknown, mostly due to lack of efficient methods to distinguish members of this multigene family. Nomenclature of LMW-GS alleles is also unclear, and different authors can assign different alleles to the same variety increasing confusion in the study of this complex family. The use of molecular markers for the discrimination of LMW-GS genes might be very useful in breeding programs, but their wide application is not easy. The objective of this work is to gain insight into the relationship between glutenins and bread quality, and the developing of molecular markers that help in the allele classification of HMW-GS and LMW-GS. Two populations of advanced lines F4:6 were obtained from the cross ‘Tigre’ x ‘Gazul’ and ‘Fiel’ x ‘Taber’. Lines homogeneous for HMW-GS, LMW-GS and gliadins pattern were selected for quality analysis. The allele classification of HMW-GS was performed by SDS-PAGE, and then complemented by PCR analysis. A new PCR marker was developed to undoubtedly differentiate between two similar subunits from Glu-B1 locus, Bx7 and Bx7*. The allele classification of LMW-GS was initially performed by SDS-PAGE following different established nomenclatures and using standard varieties. The results were not completely concluding for Glu-B3 locus, so a molecular marker system was applied. DNA from parental lines and standard varieties was amplified using primers designed in conserved domains of LMW genes and analyzed by capillary electrophoresis. The pattern of amplification products obtained was compared among samples and related to the protein allele classification. It was possible to establish a correspondence between specific amplification products and almost all LMW alleles analyzed. With this method, the allele classification of the four parental lines was clarified. Flour quality of F4:6 advanced lines were tested by protein content, sedimentation test (SDSS) and alveograph (P, L, P/L and W). The values were analyzed in relation to the lines prolamin composition. In the ‘Fiel’ x ‘Taber’ population, Glu-A3 locus showed an influence in SDSS values. Lines carrying new allele Glu-A3b’, presented a significantly higher SDSS value than lines with Glu-A3f allele. In the ‘Tigre ’x ‘Gazul’ population, the Glu-B1 and Glu-B3 loci also showed an effect in quality parameters, in SDSS, and P and L values. Results indicated that: for SDSS and P, lines with Bx7OE+By8 were significantly better than lines with Bx17+By18; lines carrying Glu-B3ac allele had a significantly higher P values than Glu-B3ad allele values. lines with and lower L The analysis of quality parameters and amplified LMW fragments revealed a significant influence of two peaks (2-616 y 2-636) in P values. The presence of 2-636 peak gave higher P values than 2-616. These fragments had been cloned and sequenced and identified as Glu-B3 genes. The sequence analysis revealed that the molecular difference between them was some SNPs and a small deletion of 21 nucleotides that in the protein would produce an InDel of a heptapeptide in the repetitive region. In this work, the analysis of two crosses with differences in Glu-3 composition has made possible to study the influence of LMG-GS in quality parameters. Specifically, the influence of Glu-B3, the most interesting and less studied loci has been possible. The results have shown that Glu-B3 allele composition influences the alveograph parameter P (tenacity). The existence of different molecular variants of Glu-B3 alleles have been assessed by using a molecular marker method. This work supports the use of molecular approaches in the study of the very complex LMW-GS family, and validates their application in the analysis of advanced recombinant lines for quality studies.

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Resumen En la última década la tecnología láser se ha convertido en una herramienta imprescindible en la fabricación de dispositivos fotovoltaicos, muy especial¬mente en aquellos basados en tecnología de lámina delgada. Independiente¬mente de crisis coyunturales en el sector, la evolución en los próximos años de estas tecnologías seguirá aprovechándose de la flexibilidad y calidad de proceso de la herramienta láser para la consecución de los dos objetivos básicos que harán de la fotovoltaica una opción energética económicamente viable: la reducción de costes de fabricación y el aumento de eficiencia de los dispositivos. Dentro de las tecnologías fotovoltaicas de lámina delgada, la tecnología de dispositivos basados en silicio amorfo ha tenido un gran desarrollo en sistemas estándar en configuración de superestrato, pero su limitada efi¬ciencia hace que su supervivencia futura pase por el desarrollo de formatos en configuración de substrato sobre materiales flexibles de bajo coste. En esta aproximación, las soluciones industriales basadas en láser actualmente disponibles para la interconexión monolítica de dispositivos no son aplica¬bles, y desde hace años se viene investigando en la búsqueda de soluciones apropiadas para el desarrollo de dichos procesos de interconexión de forma que sean transferibles a la industria. En este contexto, esta Tesis propone una aproximación completamente orig¬inal, demostrando la posibilidad de ejecutar una interconexión completa de estos dispositivos irradiando por el lado de la lámina (es decir de forma com¬patible con la opción de configuración de substrato y, valga la redundancia, con el substrato del dispositivo opaco), y con fuentes láser emitiendo en UV. Este resultado, obtenido por primera vez a nivel internacional con este trabajo, aporta un conocimiento revelador del verdadero potencial de estas fuentes en el desarrollo industrial futuro de estas tecnologías. Si bien muy posiblemente la solución industrial final requiera de una solución mixta con el empleo de fuentes en UV y, posiblemente, en otras longitudes de onda, esta Tesis y su planteamiento novedoso aportan un conocimiento de gran valor a la comunidad internacional por la originalidad del planteamiento seguido, los resultados parciales encontrados en su desarrollo (un número importante de los cuales han aparecido en revistas del JCR que recogen en la actualidad un número muy significativo de citas) y porque saca además a la luz, con las consideraciones físicas pertinentes, las limitaciones intrínsecas que el desarrollo de procesos de ablación directa selectiva con láseres UV en parte de los materiales utilizados presenta en el rango temporal de in¬teracción de ns y ps. En este trabajo se han desarrollado y optimizado los tres pasos estándar de interconexión (los habitualmente denominados Pl, P2 y P3 en la industria fotovoltaica) demostrando las ventajas y limitaciones del uso de fuentes en UV tanto con ancho temporal de ns como de ps. En particular destaca, por el éxito en los resultados obtenidos, el estudio de procesos de ablación selectiva de óxidos conductores transparentes (en este trabajo utilizados tanto como contacto frontal así como posterior en los módulos) que ha generado resultados, de excelente acogida científica a nivel internacional, cuya aplicación trasciende el ámbito de las tecnologías de silicio amorfo en lámina delgada. Además en este trabajo de Tesis, en el desarrollo del objetivo citado, se han puesto a punto técnicas de análisis de los procesos láser, basadas en métodos avanzados de caracterización de materiales (como el uso combi¬nado de la espectroscopia dispersiva de rayos X y la microscopía confocal de barrido) que se presentan como auténticos avances en el desarrollo de técnicas específicas de caracterización para el estudio de los procesos con láser de ablación selectiva de materiales en lámina delgada, procesos que no solo tienen impacto en el ámbito de la fotovoltaica, sino también en la microelectrónica, la biotecnología, la microfabricación, etc. Como resultado adicional, parte de los resultados de este trabajo, han sido aplicados exi¬tosamente por el grupo de investigaci´on en la que la autora desarrolla su labor para conseguir desarrollar procesos de enorme inter´es en otras tec-nolog´ıas fotovoltaicas, como las tecnolog´ıas est´andar de silicio amorfo sobre vidrio en configuraci´on de superestrato o el procesado de capas delgadas en tecnolog´ıas convencionales de silicio cristalino. Por u´ltimo decir que este trabajo ha sido posible por una colaboraci´on muy estrecha entre el Centro L´aser de la UPM, en el que la autora de¬sarrolla su labor, y el Grupo de Silicio Depositado del Centro de Inves¬tigaciones Energ´eticas, Medioambientales y Tecnol´ogicas, CIEMAT, que, junto al Grupo de Energ´ıa Fotovoltaica de la Universidad de Barcelona, han preparado la mayor parte de las muestras utilizadas en este estudio. Dichas colaboraciones se han desarrollado en el marco de varios proyectos de investigaci´on aplicada con subvenci´on pu´blica, tales como el proyecto singular estrat´egico PSE-MICROSIL08 (PSE-120000-2006-6), el proyecto INNDISOL (IPT-420000-2010-6), ambos financiados porel Fondo Europeo de Desarrollo Regional FEDER (UE) ”Una manera de hacer Europa y el MICINN, y los proyectos de Plan Nacional AMIC (ENE2010-21384-C04-´ 02) y CLASICO (ENE2007-6772-C04-04), cuya financiaci´on ha permitido en gran parte llevar a t´ermino este trabajo Abstract In the last decade, the laser technology has turned into an indispensable tool in the production of photovoltaic devices, especially of those based on thin film technology. Regardless the current crisis in the sector, the evolution of these technologies in the upcoming years will keep taking advantage of the flexibility and process quality of the laser tool for the accomplishment of the two basic goals that will convert the photovoltaic energy into economically viable: the manufacture cost reduction and the increase in the efficiency of the devices. Amongst the thin film laser technologies, the technology of devices based on amorphous silicon has had a great development in standard systems of superstrate configuration, but its limited efficiency makes its survival de¬pendant on the development of formats in substrate configuration with low cost flexible materials. In this approach, the laser industrial solutions cur¬rently available for the monolithic interconnection are not applicable, and in the last few years the investigations have been focused on the search of appropriate solutions for the development of such interconnection processes in a way that the same are transferable to the industry. In this context, this Thesis proposes a totally original approach, proving the possibility of executing a full interconnection of these devices by means of irradiation from the film side, i.e., compatible with the substrate con¬figuration, and with UV laser sources. This result, obtained for the first time at international level in this work, provides a revealing knowledge of the true potential of these sources in the future industrial development of these technologies. Even though very probably the final industrial solution will require a combination of the use of UV sources along with other wave¬lengths, this Thesis and its novel approach contribute with a high value to the international community because of the originality of the approach, the partial results found throughout its development (out of which, a large number has appeared in JCR journals that currently accumulate a signifi¬cant number of citations) and brings to light, with the pertinent scientific considerations, the intrinsic limitations that the selective direct ablation processes with UV laser present in the temporal range of interaction of ns and ps for part of the materials used in this study. More particularly, the three standard steps of interconnection (usually de¬nominated P1, P2 and P3 in the photovoltaic industry) have been developed and optimized, showing the advantages as well as the limitations of the use of UV sources in both the ns and ps pulse-width ranges. It is highly remark¬able, because of the success in the obtained results, the study of selective ablation processes in transparent conductive oxide (in this work used as a front and back contact), that has generated results, of excellent interna¬tional scientific reception, whose applications go beyond the scope of thin film photovoltaic technologies based on amorphous silicon. Moreover, in this Thesis, with the development of the mentioned goal, differ¬ent techniques of analysis of laser processes have been fine-tuned, basing the same in advanced methods for material characterization (like the combined use of EDX Analysis and Confocal Laser Scanning Microscopy) that can be presented as true breakthroughs in the development of specific techniques for characterization in the study of laser processes of selective ablation of materials in thin film technologies, processes that not only have impact in the photovoltaic field, but also in those of microelectronics, biotechnology, micro-fabrication, etc. As an additional outcome, part of the results of this work has been suc¬cessfully applied, by the investigation group to which the author belongs, to the development of processes of enormous interest within other photo¬voltaic technologies, such as the standard technologies on amorphous silicon over glass in superstrate configuration or the processing of thin layers in conventional technologies using crystalline silicon. Lastly, it is important to mention that this work has been possible thanks to the close cooperation between the Centro L´aser of the UPM, in which the author develops her work, and the Grupo de Silicio Depositado of Centro de Investigaciones Energ´eticas, Medioambientales y Tecnol´ogicas, CIEMAT, which, along with the Grupo de Energ´ıa Fotovoltaica of Univer¬sidad de Barcelona, has prepared the largest part of the samples utilized in this study. Such collaborations have been carried out in the context of several projects of applied investigation with public funding, like Proyecto Singular Estrat´egico PSE-MICROSIL08 (PSE-120000-2006-6), Proyecto IN-NDISOL (IPT-420000-2010-6), both funded by the European Regional De¬velopment Fund (ERDF), ”Una manera de hacer Europa” and MICINN, and the projects of Plan Nacional AMIC (ENE2010-21384-C04-02) and ´ CLASICO (ENE2007-6772-C04-04), whose funds have enabled the devel-opment of large part of this work.

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A participatory modelling process has been conducted in two areas of the Guadiana river (the upper and the middle sub-basins), in Spain, with the aim of providing support for decision making in the water management field. The area has a semi-arid climate where irrigated agriculture plays a key role in the economic development of the region and accounts for around 90% of water use. Following the guidelines of the European Water Framework Directive, we promote stakeholder involvement in water management with the aim to achieve an improved understanding of the water system and to encourage the exchange of knowledge and views between stakeholders in order to help building a shared vision of the system. At the same time, the resulting models, which integrate the different sectors and views, provide some insight of the impacts that different management options and possible future scenarios could have. The methodology is based on a Bayesian network combined with an economic model and, in the middle Guadiana sub-basin, with a crop model. The resulting integrated modelling framework is used to simulate possible water policy, market and climate scenarios to find out the impacts of those scenarios on farm income and on the environment. At the end of the modelling process, an evaluation questionnaire was filled by participants in both sub-basins. Results show that this type of processes are found very helpful by stakeholders to improve the system understanding, to understand each others views and to reduce conflict when it exists. In addition, they found the model an extremely useful tool to support management. The graphical interface, the quantitative output and the explicit representation of uncertainty helped stakeholders to better understand the implications of the scenario tested. Finally, the combination of different types of models was also found very useful, as it allowed exploring in detail specific aspects of the water management problems.

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The aim of this Thesis is to get in deep in the use of models (conceptual and numerical), as a prediction and analytical tool for hydrogeological studies, mainly from point of view of the mining drainage. In the first place, are developed the basic concepts and the parametric variations range are developed, usually used in the modelization of underground f10w and particle transport, and also the more recommended modelization process, analysing step by step each of its sequences, developed based in the experience of the author, contrasted against the available bibliography. Following MODFLOW is described, as a modelization tool, taking into account the advantages that its more common pre/post-treatment software have (Processing MODFLOW, Mod CAD and Visual MODFLOW). In third place, are introduced the criterions and required parameters to develop a conceptual model, numerical discretization, definition of the boundary and initial conditions, as well as all those factors which affects to the system (antropic or natural), developing the creation process, data introduction, execution of morlel, convergence criterions and calibration and obtaining result, natural of Visual MODFLOUI. Next, five practical cases are analysed, in which the author has been applied MODFLOW, and the different pre/post-treatment software (Processing MODFLOW, Mod CAD and Visual MODFLOW), describing for each one, the objectives, the conceptual model defined, discretization, the parametric definition, sensibility analysis, results reached and future states prediction. In fifth place, are presented a program developed by the author which allow to improve the facilities offered by Mod CAD and Visual MODFLOW, expanding modelization possibilities and connection to other computers. Next step it is presented a series of solutions to the most typical problems which could appear during the modelization with MODFLOW. Finally, the conclusions and recommendation readied are exposed, with the purpose to help in the developing of hydrogeological models both conceptuals and numericals. RESUMEN El objetivo de esta Tesis es profundizar en el empleo de modelos (conceptuales y numéricos), como herramienta de predicción y análisis en estudios hidrogeológicos, fundamentalmente desde el punto de vista de drenaje minero. En primer lugar, se desarrollan los conceptos básicos y los rangos de variación paramétrica, habituales en la modelización de flujos subterráneos y transporte de partículas, así como el proceso de modelización más recomendado, analizando paso a paso cada una de sus secuencias, desarrollado en base a la experiencia del autor, contrastado con la bibliografía disponible. Seguidamente se describe MODFLOW como herramienta de modelización, valorando las ventajas que presentan sus software de pre/post-tratamiento más comunes (Proccesing MODFLOW, Mod CAD y Visual MODFLOW). En tercer lugar, se introducen los criterios y parámetros precisos para desarrollar un modelo conceptual, discretización numérica, definición de las condiciones de contorno e iniciales, así como todos aquellos factores que afectan al sistema (antrópicos o naturales), desarrollando el proceso de creación, introducción de datos, ejecución del modelo, criterios de convergencia y calibración, y obtención de resultados, propios de Visual MODFLOW. A continuación, se analizan cinco casos prácticos, donde el autor ha aplicado MODFLOW, así como diferentes software de pre/post-tratamiento (Proccesing MODFLOW, Mod CAD y Visual MODFLOW), describiendo para cada uno, el objetivo marcado, modelo conceptual definido, discretización, definición paramétrica, análisis de sensibilidad, resultados alcanzados y predicción de estados futuros. En quinto lugar, se presenta un programa desarrollado por el autor, que permite mejorar las prestaciones ofrecidas por MODFLOW y Visual MODFLOW, ampliando las posibilidades de modelización y conexión con otros ordenadores. Seguidamente se plantean una serie de soluciones a los problemas más típicos que pueden producirse durante la modelización con MODFLOW. Por último, se exponen las conclusiones y recomendaciones alcanzadas, con el fin de auxiliar el desarrollo del desarrollo de modelos hidrogeológicos, tanto conceptuales como numéricos.

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This paper analyses empirical evidence of efforts to enable Spanish micro and small manufacturing companies to boost their labour productivity rates through the development of the main pillars of their corporate social responsibility (CSR) policies. This study aims to develop new approaches and sensibilities towards work from an ethical, values (virtues) and CSR perspective, showing how internal dimensions of CSR, such those related to relationships with employees and responsibility in processes and product quality, can improve labour performance and labour efficiency, thereby contributing to a better society. The results of a sample of 929 small businesses indicate that the social responsibility policies that most contributed to a short-term increase in labour productivity are those related to internal aspects of the company, in particular its involvement in the quality of processes and products, promotion of innovation and employee care. However, the impact on labour productivity of CSR policies related to external factors, such as relationship with stakeholders and environmental concern, could not be empirically proven in this paper.

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El desarrollo de actividades de carga y descarga son parte de la esencia de la naturaleza funcional de un puerto, de las cuales derivan en gran medida los ingresos del mismo y la eficiencia de la cadena logística en su conjunto. Las oscilaciones en el interior de una dársena y en un línea de atraque disminuyen la calidad de la estancia de las embarcaciones en puerto, reducen el rendimiento de la estiba de los buques y solicitan y fatigan las estructuras y los cuerpos flotantes amarrados. Si los parámetros que definen la agitación local se aproximan a regiones de fallo 0 parada, el subsistema pierde rendimiento, fiabilidad y finalmente se paralizan las operaciones, produciéndose de este modo tiempos de inactividad. Estas paradas operativas conllevan pérdidas económicas para la terminal y, consecuentemente, para el puerto. Hoy día se dispone vastas redes de monitorización destinadas a la caracterización del medio físico en el entorno de los puertos. Paralelamente, las operaciones de manipulación de cargas en las terminales se están dirigiendo hacia modelos de automatización o semi automatización, que permiten no sólo la sistematización de procesos, sino también un profundo conocimiento del flujo de tareas. En este contexto hay un déficit de información sobre cómo afectan los diferentes forzadores del medio físico al rendimiento, la seguridad funcionalidad del proceso de manipulación de carga y descarga. Esto se debe en gran medida a la falta de registros dilatados en el tiempo que permitan correlacionar todos los aspectos mencionados de un modo particularizado para cada línea de atraque y amarre de un puerto. En esta tesis se desarrolla una metodología de vídeo monitorización no intrusiva y de bajo coste basada en la aplicación de técnicas "pixel tool' y la obtención de los parámetros extrínsecos de una observación monofocal. Con ello pretende poner en valor las infraestructuras de vídeo vigilancia de los puertos y de los laboratorios de experimentación a escala reducida, con el objeto de facilitar el estudio los umbrales operativos de las áreas de atraque y amarre. The development of loading and unloading activities is an essential part of he functional nature of a port, which derive largely from he same income and the efficiency of he supply chain as a whole. The oscillations inside a dock and a mooring line diminish he quality of the stay of vessels in port reducing the performance of the stowage of ship and asking and fatigued structures and moored floating bodies. If the parameters defining the local al agitation regions are close to areas of failure or shutdown, he subsystem looses performance, reliability and eventually paralyzes the operations, thereby producing downtime. These operational stops entail economic 1osses to the terminal and, consequently for the port. Today vast networks of monitoring, aimed at he characterization of the physical environment in the vicinity of he ports, are available. In parallel, the cargo handling operations at terminals are moving towards automation or semi-automation models that allow not only the systematization of processes, but also a deep understanding of he workflow. In this context, there is a lack of information about how the different forcing agents of the physical environment affect the performance and he functional safety of the loading and unloading process. This is due largely to the lack of spread-over-time records which would allow to correlate all aspects mentioned, specifically, for each berthing and mooring of a port. This thesis develops a methodology for non-intrusive and low cost monitoring video based on the application of "pixel tool" techniques and on obtaining the extrinsic parameters of a monofocal observation. It seeks an enhancement of the video monitoring infrastructure at ports and at experimental laboratories of reduced scale, in order to facilitate the study of operational thresholds berthing and mooring areas.

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La tecnología moderna de computación ha permitido cambiar radicalmente la investigación tecnológica en todos los ámbitos. El proceso general utilizado previamente consistía en el desarrollo de prototipos analógicos, creando múltiples versiones del mismo hasta llegar al resultado adecuado. Este es un proceso costoso a nivel económico y de carga de trabajo. Es por ello por lo que el proceso de investigación actual aprovecha las nuevas tecnologías para lograr el objetivo final mediante la simulación. Gracias al desarrollo de software para la simulación de distintas áreas se ha incrementado el ritmo de crecimiento de los avances tecnológicos y reducido el coste de los proyectos en investigación y desarrollo. La simulación, por tanto, permite desarrollar previamente prototipos simulados con un coste mucho menor para así lograr un producto final, el cual será llevado a cabo en su ámbito correspondiente. Este proceso no sólo se aplica en el caso de productos con circuitería, si bien es utilizado también en productos programados. Muchos de los programas actuales trabajan con algoritmos concretos cuyo funcionamiento debe ser comprobado previamente, para después centrarse en la codificación del mismo. Es en este punto donde se encuentra el objetivo de este proyecto, simular algoritmos de procesado digital de la señal antes de la codificación del programa final. Los sistemas de audio están basados en su totalidad en algoritmos de procesado de la señal, tanto analógicos como digitales, siendo estos últimos los que están sustituyendo al mundo analógico mediante los procesadores y los ordenadores. Estos algoritmos son la parte más compleja del sistema, y es la creación de nuevos algoritmos la base para lograr sistemas de audio novedosos y funcionales. Se debe destacar que los grupos de desarrollo de sistemas de audio presentan un amplio número de miembros con cometidos diferentes, separando las funciones de programadores e ingenieros de la señal de audio. Es por ello por lo que la simulación de estos algoritmos es fundamental a la hora de desarrollar nuevos y más potentes sistemas de audio. Matlab es una de las herramientas fundamentales para la simulación por ordenador, la cual presenta utilidades para desarrollar proyectos en distintos ámbitos. Sin embargo, en creciente uso actualmente se encuentra el software Simulink, herramienta especializada en la simulación de alto nivel que simplifica la dificultad de la programación en Matlab y permite desarrollar modelos de forma más rápida. Simulink presenta una completa funcionalidad para el desarrollo de algoritmos de procesado digital de audio. Por ello, el objetivo de este proyecto es el estudio de las capacidades de Simulink para generar sistemas de audio funcionales. A su vez, este proyecto pretende profundizar en los métodos de procesado digital de la señal de audio, logrando al final un paquete de sistemas de audio compatible con los programas de edición de audio actuales. ABSTRACT. Modern computer technology has dramatically changed the technological research in multiple areas. The overall process previously used consisted of the development of analog prototypes, creating multiple versions to reach the proper result. This is an expensive process in terms of an economically level and workload. For this reason actual investigation process take advantage of the new technologies to achieve the final objective through simulation. Thanks to the software development for simulation in different areas the growth rate of technological progress has been increased and the cost of research and development projects has been decreased. Hence, simulation allows previously the development of simulated protoypes with a much lower cost to obtain a final product, which will be held in its respective field. This process is not only applied in the case of circuitry products, but is also used in programmed products. Many current programs work with specific algorithms whose performance should be tested beforehand, which allows focusing on the codification of the program. This is the main point of this project, to simulate digital signal processing algorithms before the codification of the final program. Audio systems are entirely based on signal processing, both analog and digital systems, being the digital systems which are replacing the analog world thanks to the processors and computers. This algorithms are the most complex part of every system, and the creation of new algorithms is the most important step to achieve innovative and functional new audio systems. It should be noted that development groups of audio systems have a large number of members with different roles, separating them into programmers and audio signal engineers. For this reason, the simulation of this algorithms is essential when developing new and more powerful audio systems. Matlab is one of the most important tools for computer simulation, which has utilities to develop projects in different areas. However, the use of the Simulink software is constantly growing. It is a simulation tool specialized in high-level simulations which simplifies the difficulty of programming in Matlab and allows the developing of models faster. Simulink presents a full functionality for the development of algorithms for digital audio processing. Therefore, the objective of this project is to study the posibilities of Simulink to generate funcional audio systems. In turn, this projects aims to get deeper into the methods of digital audio signal processing, making at the end a software package of audio systems compatible with the current audio editing software.

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La relación entre la ingeniería y la medicina cada vez se está haciendo más estrecha, y debido a esto se ha creado una nueva disciplina, la bioingeniería, ámbito en el que se centra el proyecto. Este ámbito cobra gran interés debido al rápido desarrollo de nuevas tecnologías que en particular permiten, facilitan y mejoran la obtención de diagnósticos médicos respecto de los métodos tradicionales. Dentro de la bioingeniería, el campo que está teniendo mayor desarrollo es el de la imagen médica, gracias al cual se pueden obtener imágenes del interior del cuerpo humano con métodos no invasivos y sin necesidad de recurrir a la cirugía. Mediante métodos como la resonancia magnética, rayos X, medicina nuclear o ultrasonidos, se pueden obtener imágenes del cuerpo humano para realizar diagnósticos. Para que esas imágenes puedan ser utilizadas con ese fin hay que realizar un correcto tratamiento de éstas mediante técnicas de procesado digital. En ése ámbito del procesado digital de las imágenes médicas es en el que se ha realizado este proyecto. Gracias al desarrollo del tratamiento digital de imágenes con métodos de extracción de información, mejora de la visualización o resaltado de rasgos de interés de las imágenes, se puede facilitar y mejorar el diagnóstico de los especialistas. Por todo esto en una época en la que se quieren automatizar todos los procesos para mejorar la eficacia del trabajo realizado, el automatizar el procesado de las imágenes para extraer información con mayor facilidad, es muy útil. Actualmente una de las herramientas más potentes en el tratamiento de imágenes médicas es Matlab, gracias a su toolbox de procesado de imágenes. Por ello se eligió este software para el desarrollo de la parte práctica de este proyecto, su potencia y versatilidad simplifican la implementación de algoritmos. Este proyecto se estructura en dos partes. En la primera se realiza una descripción general de las diferentes modalidades de obtención de imágenes médicas y se explican los diferentes usos de cada método, dependiendo del campo de aplicación. Posteriormente se hace una descripción de las técnicas más importantes de procesado de imagen digital que han sido utilizadas en el proyecto. En la segunda parte se desarrollan cuatro aplicaciones en Matlab para ejemplificar el desarrollo de algoritmos de procesado de imágenes médicas. Dichas implementaciones demuestran la aplicación y utilidad de los conceptos explicados anteriormente en la parte teórica, como la segmentación y operaciones de filtrado espacial de la imagen, así como otros conceptos específicos. Las aplicaciones ejemplo desarrolladas han sido: obtención del porcentaje de metástasis de un tejido, diagnóstico de las deformidades de la columna vertebral, obtención de la MTF de una cámara de rayos gamma y medida del área de un fibroadenoma de una ecografía de mama. Por último, para cada una de las aplicaciones se detallará su utilidad en el campo de la imagen médica, los resultados obtenidos y su implementación en una interfaz gráfica para facilitar su uso. ABSTRACT. The relationship between medicine and engineering is becoming closer than ever giving birth to a recently appeared science field: bioengineering. This project is focused on this subject. This recent field is becoming more and more important due to the fast development of new technologies that provide tools to improve disease diagnosis, with regard to traditional procedures. In bioengineering the fastest growing field is medical imaging, in which we can obtain images of the inside of the human body without need of surgery. Nowadays by means of the medical modalities of magnetic resonance, X ray, nuclear medicine or ultrasound, we can obtain images to make a more accurate diagnosis. For those images to be useful within the medical field, they should be processed properly with some digital image processing techniques. It is in this field of digital medical image processing where this project is developed. Thanks to the development of digital image processing providing methods for data collection, improved visualization or data highlighting, diagnosis can be eased and facilitated. In an age where automation of processes is much sought, automated digital image processing to ease data collection is extremely useful. One of the most powerful image processing tools is Matlab, together with its image processing toolbox. That is the reason why that software was chosen to develop the practical algorithms in this project. This final project is divided into two main parts. Firstly, the different modalities for obtaining medical images will be described. The different usages of each method according to the application will also be specified. Afterwards we will give a brief description of the most important image processing tools that have been used in the project. Secondly, four algorithms in Matlab are implemented, to provide practical examples of medical image processing algorithms. This implementation shows the usefulness of the concepts previously explained in the first part, such as: segmentation or spatial filtering. The particular applications examples that have been developed are: calculation of the metastasis percentage of a tissue, diagnosis of spinal deformity, approximation to the MTF of a gamma camera, and measurement of the area of a fibroadenoma in an ultrasound image. Finally, for each of the applications developed, we will detail its usefulness within the medical field, the results obtained, and its implementation in a graphical user interface to ensure ease of use.

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Two important characteristics of science are the ?reproducibility? and ?clarity?. By rigorous practices, scientists explore aspects of the world that they can reproduce under carefully controlled experimental conditions. The clarity, complementing reproducibility, provides unambiguous descriptions of results in a mechanical or mathematical form. Both pillars depend on well-structured and accurate descriptions of scientific practices, which are normally recorded in experimental protocols, scientific workflows, etc. Here we present SMART Protocols (SP), our ontology-based approach for representing experimental protocols and our contribution to clarity and reproducibility. SP delivers an unambiguous description of processes by means of which data is produced; by doing so, we argue, it facilitates reproducibility. Moreover, SP is thought to be part of e-science infrastructures. SP results from the analysis of 175 protocols; from this dataset, we extracted common elements. From our analysis, we identified document, workflow and domain-specific aspects in the representation of experimental protocols. The ontology is available at http://purl.org/net/SMARTprotocol

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En paralelo a la superficie cotidiana de la ciudad moderna, discurre otra "ciudad invisible" o "caja negra" tecnológica, que opera, de manera silenciosa e imperceptible, al servicio de los ciudadanos. Paradójicamente, en este espacio invisible, se toman decisiones de la máxima relevancia para la ciudad: en la "caja negra", las ciudades pactan sus relaciones con la naturaleza; a través de ella, se produce la administración y distribución de los recursos que componen su metabolismo urbano. En definitiva, la "caja negra" es el conjunto de las arquitecturas donde se urbaniza la naturaleza, donde ésta pasa a ser ciudad. Y, sin embargo, ha tendido a permanecer invisible. No obstante, en el último tercio del siglo XX, se ha "abierto la caja negra" urbana y lo que era invisible ha dejado de serlo o, al menos, ha alterado su estatuto de visibilidad. El objetivo de esta tesis doctoral es evaluar las repercusiones arquitectónicas, urbanísticas y ecológicas, que conlleva este reciente fenómeno urbano que, desde hace unas décadas, está teniendo lugar en muchas de las ciudades herederas de las grandes reformas urbanas acometidas en las metrópolis europeas durante el siglo XIX, bajo el paradigma simbólico de un proyecto moderno "prometeico" y emancipador. Para abordar dicho análisis, se pondrán en relación dos parámetros urbanos elementales que han tendido a ser estudiados por separado. Por un lado, la "ecología política urbana", es decir, la red de relaciones socio-ecológicas que acontecen en la ciudad. Por otro lado, la "economía de la visibilidad", es decir, las formas de articular lo visible y lo invisible, en relación a los marcos de gobernanza. La intersección entre la "ecología política urbana" y la "economía de la visibilidad" proporciona un marco de análisis efectivo para comprender el fenómeno de la "apertura de la caja negra" y conlleva un cuestionamiento de algunas nociones dominantes en la teoría urbana y arquitectónica clásicas, como la segregación de la naturaleza, las infraestructuras y la sociedad o como las formas tradicionales de explotación ecológica del medio. Además, ofrece un criterio de análisis privilegiado para la comprensión del proceso de deslegitimación (filosófica, arquitectónica, económica, así como desde perspectivas ecológicas, sociales, de género o queer) de los modelos urbanísticos integrales modernos, herederos de los marcos antropocéntricos del siglo XIX. Por último, proporciona algunas herramientas arquitectónicas para afrontar los desafíos ecosistémicos del siglo XXI. A través del estudio de autores relevantes que han analizado esta problemática para la arquitectura, así como del estudio de casos arquitectónicos que han marcado hitos fundamentales en la consolidación urbana de los procesos asociados a la "caja negra", se concluirá que, en términos ecológicos, la ciudad moderna ha movilizado una "ecología política urbana" basada en fórmulas de sometimiento del entorno, a partir de operaciones arquitectónicas y tecnológicas invisibles. En esta tesis doctoral se estudiará la organización arquitectónica de las arquitecturas de la "caja negra" y se evaluará si el fenómeno de la "apertura de la caja negra" puede ser considerado como un síntoma de la alteración en la "ecología política urbana". 'Abriremos la caja negra" para estudiar cómo se integran en el espacio urbano los dispositivos tecnológicos de escala urbana, toda vez éstos han dejado de ser invisibles. Cómo participan, como un actor más, en la configuración de otros marcos de cohabitación, dentro de la ciudad contemporánea. ABSTRACT An 'invisible city' or technological 'black box' runs parallel to the day-to-day surface of modern cities, remaining silent, unnoticed, at the service of the citizenry. Paradoxically, this invisible space is where some of the most relevant decisions concerning the city are made: the 'black box' is where cities agree on their relationships with nature; it is used to manage and distribute the resources that form its urban metabolism. In short, the 'black box' is the collection of architectures where nature is urbanised, where it becomes a city. And in spite of all this, it has mostly remained invisible. Nevertheless, this urban 'black box' was opened during the last third of the 20th century, so what used to be invisible is invisible no more, or at least the laws governing its visibility have been altered. The purpose of this doctoral thesis is to evaluate the architectural, urban planning and ecological repercussions of this recent urban phenomenon that has been taking place for several decades in many of the cities that followed in the footsteps of the large European metropolises of the 19th century, under the symbolic paradigm of a modern 'prometheic' and emancipating project. This analysis shall be done by juxtaposing two basic urban parameters that in general have been studied separately: frstly the ‘urban political ecology', that is, the network of socio-ecological relationships within the city. Secondly, the 'economy of visibility', that is, the way the visible and invisible spheres are structured in relation with the governance frameworks. The intersection between the 'urban political ecology' and the 'economy of visibility' provides an effective analysis framework to understand the phenomenon of the 'opening of the black box'. It entails calling into question some of the predominant notions in classical urban and architectural theory, such as the segregation of nature, infrastructures and society, or the traditional forms of ecological usage of the environment. It also offers an exceptional analysis criterion to understand the discrediting process (from a philosophical, architectural, economic perspective, but also from the point of view of ecology, society, gender or queerness) of modern all-encompassing urban models that draw from the anthropocentric frameworks of the 19th century. Finally, it provides some architectural tools to tackle 21st-century ecosystemic challenges. The study of relevant authors that have analysed these problems for architecture, as well as the study of milestone architectural cases for the urban consolidation of processes associated to the 'black box', shall serve to reach the conclusion that, in ecological terms, modern cities have mobilised an 'urban political ecology' based on formulas of subjugation of the environment, through invisible architectural and technological operations. This thesis shall present an evaluation of whether the phenomenon of the 'opening of the black box' can be considered a symptom of the alteration of the 'urban political ecology'. We shall 'open the black box' to study the integration of the various urbanscale technological devices within the urban landscape, now that they have ceased to be invisible. We shall see how they participate, like any other actor, in the confguration of other cohabitation frameworks within today's cities.

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The distributed computing models typically assume every process in the system has a distinct identifier (ID) or each process is programmed differently, which is named as eponymous system. In such kind of distributed systems, the unique ID is helpful to solve problems: it can be incorporated into messages to make them trackable (i.e., to or from which process they are sent) to facilitate the message transmission; several problems (leader election, consensus, etc.) can be solved without the information of network property in priori if processes have unique IDs; messages in the register of one process will not be overwritten by others process if this process announces; it is useful to break the symmetry. Hence, eponymous systems have influenced the distributed computing community significantly either in theory or in practice. However, every thing in the world has its own two sides. The unique ID also has disadvantages: it can leak information of the network(size); processes in the system have no privacy; assign unique ID is costly in bulk-production(e.g, sensors). Hence, homonymous system is appeared. If some processes share the same ID and programmed identically is called homonymous system. Furthermore, if all processes shared the same ID or have no ID is named as anonymous system. In homonymous or anonymous distributed systems, the symmetry problem (i.e., how to distinguish messages sent from which process) is the main obstacle in the design of algorithms. This thesis is aimed to propose different symmetry break methods (e.g., random function, counting technique, etc.) to solve agreement problem. Agreement is a fundamental problem in distributed computing including a family of abstractions. In this thesis, we mainly focus on the design of consensus, set agreement, broadcast algorithms in anonymous and homonymous distributed systems. Firstly, the fault-tolerant broadcast abstraction is studied in anonymous systems with reliable or fair lossy communication channels separately. Two classes of anonymous failure detectors AΘ and AP∗ are proposed, and both of them together with a already proposed failure detector ψ are implemented and used to enrich the system model to implement broadcast abstraction. Then, in the study of the consensus abstraction, it is proved the AΩ′ failure detector class is strictly weaker than AΩ and AΩ′ is implementable. The first implementation of consensus in anonymous asynchronous distributed systems augmented with AΩ′ and where a majority of processes does not crash. Finally, a general consensus problem– k-set agreement is researched and the weakest failure detector L used to solve it, in asynchronous message passing systems where processes may crash and recover, with homonyms (i.e., processes may have equal identities), and without a complete initial knowledge of the membership.

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Emotion is generally argued to be an influence on the behavior of life systems, largely concerning flexibility and adaptivity. The way in which life systems acts in response to a particular situations of the environment, has revealed the decisive and crucial importance of this feature in the success of behaviors. And this source of inspiration has influenced the way of thinking artificial systems. During the last decades, artificial systems have undergone such an evolution that each day more are integrated in our daily life. They have become greater in complexity, and the subsequent effects are related to an increased demand of systems that ensure resilience, robustness, availability, security or safety among others. All of them questions that raise quite a fundamental challenges in control design. This thesis has been developed under the framework of the Autonomous System project, a.k.a the ASys-Project. Short-term objectives of immediate application are focused on to design improved systems, and the approaching of intelligence in control strategies. Besides this, long-term objectives underlying ASys-Project concentrate on high order capabilities such as cognition, awareness and autonomy. This thesis is placed within the general fields of Engineery and Emotion science, and provides a theoretical foundation for engineering and designing computational emotion for artificial systems. The starting question that has grounded this thesis aims the problem of emotion--based autonomy. And how to feedback systems with valuable meaning has conformed the general objective. Both the starting question and the general objective, have underlaid the study of emotion, the influence on systems behavior, the key foundations that justify this feature in life systems, how emotion is integrated within the normal operation, and how this entire problem of emotion can be explained in artificial systems. By assuming essential differences concerning structure, purpose and operation between life and artificial systems, the essential motivation has been the exploration of what emotion solves in nature to afterwards analyze analogies for man--made systems. This work provides a reference model in which a collection of entities, relationships, models, functions and informational artifacts, are all interacting to provide the system with non-explicit knowledge under the form of emotion-like relevances. This solution aims to provide a reference model under which to design solutions for emotional operation, but related to the real needs of artificial systems. The proposal consists of a multi-purpose architecture that implement two broad modules in order to attend: (a) the range of processes related to the environment affectation, and (b) the range or processes related to the emotion perception-like and the higher levels of reasoning. This has required an intense and critical analysis beyond the state of the art around the most relevant theories of emotion and technical systems, in order to obtain the required support for those foundations that sustain each model. The problem has been interpreted and is described on the basis of AGSys, an agent assumed with the minimum rationality as to provide the capability to perform emotional assessment. AGSys is a conceptualization of a Model-based Cognitive agent that embodies an inner agent ESys, the responsible of performing the emotional operation inside of AGSys. The solution consists of multiple computational modules working federated, and aimed at conforming a mutual feedback loop between AGSys and ESys. Throughout this solution, the environment and the effects that might influence over the system are described as different problems. While AGSys operates as a common system within the external environment, ESys is designed to operate within a conceptualized inner environment. And this inner environment is built on the basis of those relevances that might occur inside of AGSys in the interaction with the external environment. This allows for a high-quality separate reasoning concerning mission goals defined in AGSys, and emotional goals defined in ESys. This way, it is provided a possible path for high-level reasoning under the influence of goals congruence. High-level reasoning model uses knowledge about emotional goals stability, letting this way new directions in which mission goals might be assessed under the situational state of this stability. This high-level reasoning is grounded by the work of MEP, a model of emotion perception that is thought as an analogy of a well-known theory in emotion science. The work of this model is described under the operation of a recursive-like process labeled as R-Loop, together with a system of emotional goals that are assumed as individual agents. This way, AGSys integrates knowledge that concerns the relation between a perceived object, and the effect which this perception induces on the situational state of the emotional goals. This knowledge enables a high-order system of information that provides the sustain for a high-level reasoning. The extent to which this reasoning might be approached is just delineated and assumed as future work. This thesis has been studied beyond a long range of fields of knowledge. This knowledge can be structured into two main objectives: (a) the fields of psychology, cognitive science, neurology and biological sciences in order to obtain understanding concerning the problem of the emotional phenomena, and (b) a large amount of computer science branches such as Autonomic Computing (AC), Self-adaptive software, Self-X systems, Model Integrated Computing (MIC) or the paradigm of models@runtime among others, in order to obtain knowledge about tools for designing each part of the solution. The final approach has been mainly performed on the basis of the entire acquired knowledge, and described under the fields of Artificial Intelligence, Model-Based Systems (MBS), and additional mathematical formalizations to provide punctual understanding in those cases that it has been required. This approach describes a reference model to feedback systems with valuable meaning, allowing for reasoning with regard to (a) the relationship between the environment and the relevance of the effects on the system, and (b) dynamical evaluations concerning the inner situational state of the system as a result of those effects. And this reasoning provides a framework of distinguishable states of AGSys derived from its own circumstances, that can be assumed as artificial emotion.