Nuevo paradigma para decisiones colectivas en entornos no competitivos

La tesis estudia uno de los aspectos más importantes de la gestión de la sociedad de la información: conocer la manera en que una persona valora cualquier situación. Esto es importante para el individuo que realiza la valoración y para el entorno con el que se relaciona. La valoración es el resultado de la comparación: se asignan los mismos valores a alternativas similares y mayores valores a alternativas mejor consideradas en el proceso de comparación. Los patrones que guían al individuo a la hora de hacer la comparación se derivan de sus preferencias individuales (es decir, de sus opiniones). En la tesis se presentan varios procedimientos para establecer las relaciones de preferencia entre alternativas de una persona. La valoración progresa hasta obtener una representación numérica de sus preferencias. Cuando la representación de preferencias es homogénea permite, además, contrastar las preferencias personales con las del resto de evaluadores, lo que favorece la evaluación de políticas, la transferencia de información entre diferentes individuos y el diseño de la alternativa que mejor se adapte a las preferencias identificadas. Al mismo tiempo, con esta información se pueden construir comunidades de personas con los mismos sistemas de preferencias ante una cuestión concreta. La tesis muestra un caso de aplicación de esta metodología: optimización de las políticas laborales en un mercado real. Para apoyar a los demandantes de empleo (en su iniciación o reincorporación al mundo laboral o en el cambio de su actividad) es necesario conocer sus preferencias respecto a las ocupaciones que están dispuestos a desempeñar. Además, para que la intermediación laboral sea efectiva, las ocupaciones buscadas deben de ser ofrecidas por el mercado de trabajo y el demandante debe reunir las condiciones para acceder a esas ocupaciones. El siguiente desarrollo de estos modelos nos lleva a los procedimientos utilizados para transformar múltiples preferencias en una decisión agregada y que consideran tanto la opinión de cada uno de los individuos que participan en la decisión como las interacciones sociales, todo ello dirigido a generar una solución que se ajuste lo mejor posible al punto de vista de toda la población. Las decisiones con múltiples participantes inciden, principalmente, en: el aumento del alcance para incorporar a personas que tradicionalmente no han sido consideradas en las tomas de decisiones, la agregación de las preferencias de los múltiples participantes en las tomas de decisiones colectivas (mediante votación, utilizando aplicaciones desarrolladas para la Web2.0 y a través de comparaciones interpersonales de utilidad) y, finalmente, la auto-organización para permitir que interaccionen entre si los participantes en la valoración, de forma que hagan que el resultado final sea mejor que la mera agregación de opiniones individuales. La tesis analiza los sistemas de e-democracia o herramientas para su implantación que tienen más más utilización en la actualidad o son más avanzados. Están muy relacionados con la web 2.0 y su implantación está suponiendo una evolución de la democracia actual. También se estudian aplicaciones de software de Colaboración en la toma de decisiones (Collaborative decision-making (CDM)) que ayudan a dar sentido y significado a los datos. Pretenden coordinar las funciones y características necesarias para llegar a decisiones colectivas oportunas, lo que permite a todos los interesados participar en el proceso. La tesis finaliza con la presentación de un nuevo modelo o paradigma en la toma de decisiones con múltiples participantes. El desarrollo se apoya en el cálculo de las funciones de utilidad empática. Busca la colaboración entre los individuos para que la toma de decisiones sea más efectiva, además pretende aumentar el número de personas implicadas. Estudia las interacciones y la retroalimentación entre ciudadanos, ya que la influencia de unos ciudadanos en los otros es fundamental para los procesos de toma de decisiones colectivas y de e-democracia. También incluye métodos para detectar cuando se ha estancado el proceso y se debe interrumpir. Este modelo se aplica a la consulta de los ciudadanos de un municipio sobre la oportunidad de implantar carriles-bici y las características que deben tomar. Se simula la votación e interacción entre los votantes. ABSTRACT The thesis examines one of the most important aspects of the management of the information society: get to know how a person values every situation. This is important for the individual performing the assessment and for the environment with which he interacts. The assessment is a result of the comparison: identical values are allocated to similar alternatives and higher values are assigned to those alternatives that are more favorably considered in the comparison process. Patterns that guide the individual in making the comparison are derived from his individual preferences (ie, his opinions). In the thesis several procedures to establish preference relations between alternatives a person are presented. The assessment progresses to obtain a numerical representation of his preferences. When the representation of preferences is homogeneous, it also allows the personal preferences of each individual to be compared with those of other evaluators, favoring policy evaluation, the transfer of information between different individuals and design the alternative that best suits the identified preferences. At the same time, with this information you can build communities of people with similar systems of preferences referred to a particular issue. The thesis shows a case of application of this methodology: optimization of labour policies in a real market. To be able support jobseekers (in their initiation or reinstatement to employment or when changing area of professional activity) is necessary to know their preferences for jobs that he is willing to perform. In addition, for labour mediation to be effective occupations that are sought must be offered by the labour market and the applicant must meet the conditions for access to these occupations. Further development of these models leads us to the procedures used to transform multiple preferences in an aggregate decision and consider both the views of each of the individuals involved in the decision and the social interactions, all aimed at generating a solution that best fits of the point of view of the entire population. Decisions with multiple participants mainly focus on: increasing the scope to include people who traditionally have not been considered in decision making, aggregation of the preferences of multiple participants in collective decision making (by vote, using applications developed for the Web 2.0 and through interpersonal comparisons of utility) and, finally, self-organization to allow participants to interact with each other in the assessment, so that the final result is better than the mere aggregation of individual opinions. The thesis analyzes the systems of e-democracy or tools for implementation which are more popular or more advanced. They are closely related to the Web 2.0 and its implementation is bringing an evolution of the current way of understanding democracy. We have also studied Collaborative Decision-Making (CDM)) software applications in decision-making which help to give sense and meaning to the data. They intend to coordinate the functions and features needed to reach adequate collective decisions, allowing all stakeholders to participate in the process. The thesis concludes with the presentation of a new model or paradigm in decision-making with multiple participants. The development is based on the calculation of the empathic utility functions. It seeks collaboration between individuals to make decision-making more effective; it also aims to increase the number of people involved. It studies the interactions and feedback among citizens, because the influence of some citizens in the other is fundamental to the process of collective decision-making and e-democracy. It also includes methods for detecting when the process has stalled and should be discontinued. This model is applied to the consultation of the citizens of a municipality on the opportunity to introduce bike lanes and characteristics they should have. Voting and interaction among voters is simulated.

The 2.0-Å resolution crystal structure of a trimeric antibody fragment with noncognate VH–VL domain pairs shows a rearrangement of VH CDR3

The 2.0-Å resolution x-ray crystal structure of a novel trimeric antibody fragment, a “triabody,” has been determined. The trimer is made up of polypeptides constructed in a manner identical to that previously described for some “diabodies”: a VL domain directly fused to the C terminus of a VH domain—i.e., without any linker sequence. The trimer has three Fv heads with the polypeptides arranged in a cyclic, head-to-tail fashion. For the particular structure reported here, the polypeptide was constructed with a VH domain from one antibody fused to the VL domain from an unrelated antibody giving rise to “combinatorial” Fvs upon formation of the trimer. The structure shows that the exchange of the VL domain from antibody B1-8, a Vλ domain, with the VL domain from antibody NQ11, a Vκ domain, leads to a dramatic conformational change in the VH CDR3 loop of antibody B1-8. The magnitude of this change is similar to the largest of the conformational changes observed in antibody fragments in response to antigen binding. Combinatorial pairing of VH and VL domains constitutes a major component of antibody diversity. Conformationally flexible antigen-binding sites capable of adapting to the specific CDR3 loop context created upon VH–VL pairing may be employed by the immune system to maximize the structural diversity of the immune response.

Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct

We tested whether severe congestive heart failure (CHF), a condition associated with excess free-water retention, is accompanied by altered regulation of the vasopressin-regulated water channel, aquaporin-2 (AQP2), in the renal collecting duct. CHF was induced by left coronary artery ligation. Compared with sham-operated animals, rats with CHF had severe heart failure with elevated left ventricular end-diastolic pressures (LVEDP): 26.9 ± 3.4 vs. 4.1 ± 0.3 mmHg, and reduced plasma sodium concentrations (142.2 ± 1.6 vs. 149.1 ± 1.1 mEq/liter). Quantitative immunoblotting of total kidney membrane fractions revealed a significant increase in AQP2 expression in animals with CHF (267 ± 53%, n = 12) relative to sham-operated controls (100 ± 13%, n = 14). In contrast, immunoblotting demonstrated a lack of an increase in expression of AQP1 and AQP3 water channel expression, indicating that the effect on AQP2 was selective. Furthermore, postinfarction animals without LVEDP elevation or plasma Na reduction showed no increase in AQP2 expression (121 ± 28% of sham levels, n = 6). Immunocytochemistry and immunoelectron microscopy demonstrated very abundant labeling of the apical plasma membrane and relatively little labeling of intracellular vesicles in collecting duct cells from rats with severe CHF, consistent with enhanced trafficking of AQP2 to the apical plasma membrane. The selective increase in AQP2 expression and enhanced plasma membrane targeting provide an explanation for the development of water retention and hyponatremia in severe CHF.

Fast-timing study of the l-forbidden 1/2(+) -> 3/2(+) M1 transition in Sn-129

The levels in Sn-129 populated from the beta(-) decay of In-129 isomers were investigated at the ISOLDE facility of CERN using the newly commissioned ISOLDE Decay Station (IDS). The lowest 1/2(+) state and the 3/2(+) ground state in 129Sn are expected to have configurations dominated by the neutron s(1/2) (l = 0) and d(3/2) (l = 2) single-particle states, respectively. Consequently, these states should be connected by a somewhat slow l-forbidden M1 transition. Using fast-timing spectroscopy we havemeasured the half-life of the 1/2(+) 315.3-keV state, T-1/2 = 19(10) ps, which corresponds to a moderately fast M1 transition. Shell-model calculations using the CD-Bonn effective interaction, with standard effective charges and g factors, predict a 4-ns half-life for this level. We can reconcile the shell-model calculations to the measured T-1/2 value by the renormalization of the M1 effective operator for neutron holes.

TextMess 2.0: las tecnologías del lenguaje humano ante los nuevos retos de la comunicación digital

El objetivo general de este proyecto se centra en el estudio, desarrollo y experimentación de diferentes técnicas y sistemas basados en Tecnologías del Lenguaje Humano (TLH) para el desarrollo de la próxima generación de sistemas de procesamiento inteligente de la información digital (modelado, recuperación, tratamiento, comprensión y descubrimiento) afrontando los actuales retos de la comunicación digital. En este nuevo escenario, los sistemas deben incorporar capacidades de razonamiento que descubrirán la subjetividad de la información en todos sus contextos (espacial, temporal y emocional) analizando las diferentes dimensiones de uso (multilingualidad, multimodalidad y registro).

EmotiBlog: a finer-grained and more precise learning of subjectivity expression models

The exponential growth of the subjective information in the framework of the Web 2.0 has led to the need to create Natural Language Processing tools able to analyse and process such data for multiple practical applications. They require training on specifically annotated corpora, whose level of detail must be fine enough to capture the phenomena involved. This paper presents EmotiBlog – a fine-grained annotation scheme for subjectivity. We show the manner in which it is built and demonstrate the benefits it brings to the systems using it for training, through the experiments we carried out on opinion mining and emotion detection. We employ corpora of different textual genres –a set of annotated reported speech extracted from news articles, the set of news titles annotated with polarity and emotion from the SemEval 2007 (Task 14) and ISEAR, a corpus of real-life self-expressed emotion. We also show how the model built from the EmotiBlog annotations can be enhanced with external resources. The results demonstrate that EmotiBlog, through its structure and annotation paradigm, offers high quality training data for systems dealing both with opinion mining, as well as emotion detection.

Evaluation of online tools as didactic resource in the university education

Recently, many efforts have been made in the academic world to adapt the new degrees to the new European Higher Education Area (EHEA). New technologies have been the most important factor to carry out this adaptation. In particular, the tools 2.0 have been spreading quickly, not just the Web 2.0, but even in all the educational levels. Nevertheless, it is now necessary to evaluate whether all these efforts and all the changes, carried out in order to obtain improved academic performance among students, have provided good results. Therefore, the aim of this paper is focused on studying the impact of the implementation of information and communication technologies (ICTs) in a subject belonging to a Master from the University of Alicante in the academic year (2010-2011). In special, it is an elective course called "Advanced Visual Ergonomics" from the Master of Clinical Optometry and Vision. The methodology used to teach this course differs from the traditional one in many respects. For example, one of the resources used for the development of this course is a blog developed specifically to coordinate a series of virtual works, whose purpose is that the student goes into specific aspects of the current topic. Next, the student participates in an active role by writing a personal assessment on the blog. However, in the course planning, there is an attendance to lessons, where the teacher presents certain issues in a more traditional way, that is, with a lecture supported with audiovisual materials, such as materials generated in powerpoint. To evaluate the quality of the results achieved with this methodology, in this work the personal assessment of the students, who have completed this course during this academic year, are collected. In particular, we want to know their opinion about the used resources, as well as the followed methodology. The tool used to collect this information was a questionnaire. This questionnaire evaluates different aspects of the course: a general opinion, quality of the received information, satisfaction about the followed methodology and the student´s critical awareness. The design of this questionnaire is very important to get conclusive information about the methodology followed in the course. The questionnaire has to have an adequate number of questions; whether it has many questions, it might be boring for the student who would pay no enough attention. The questions should be well-written, with a clear structure and message, to avoid confusion and an ambiguity. The questions should be objectives, without any suggestion for a desired answer. In addition, the questionnaire should be interesting to encourage the student´ s interest. In conclusion, this questionnaire developed for this subject provided good information to evaluate whether the methodology was a useful tool to teach "Advanced Visual Ergonomics". Furthermore, the student´s opinion collected by this questionnaire might be very helpful to improve this didactic resource.

Open educational resources: the role of OCW, blogs and videos in computer network classrooms

This paper analyzes the learning experiences and opinions obtained from a group of undergraduate students in their interaction with several on-line multimedia resources included in a free on-line course about Computer Networks. These new educational resources employed are based on the Web 2.0 approach such as blogs, videos and virtual labs which have been added in a web-site for distance self-learning.

MDD vs. traditional software development: a practitioner’s subjective perspective

Context: Today’s project managers have a myriad of methods to choose from for the development of software applications. However, they lack empirical data about the character of these methods in terms of usefulness, ease of use or compatibility, all of these being relevant variables to assess the developer’s intention to use them. Objective: To compare three methods, each following a different paradigm (Model-Driven, Model-Based and Code-Centric) with respect to their adoption potential by junior software developers engaged in the development of the business layer of a Web 2.0 application. Method: We have conducted a quasi-experiment with 26 graduate students of the University of Alicante. The application developed was a Social Network, which was organized around a fixed set of modules. Three of them, similar in complexity, were used for the experiment. Subjects were asked to use a different method for each module, and then to answer a questionnaire that gathered their perceptions during such use. Results: The results show that the Model-Driven method is regarded as the most useful, although it is also considered the least compatible with previous developers’ experiences. They also show that junior software developers feel comfortable with the use of models, and that they are likely to use them if the models are accompanied by a Model-Driven development environment. Conclusions: Despite their relatively low level of compatibility, Model-Driven development methods seem to show a great potential for adoption. That said, however, further experimentation is needed to make it possible to generalize the results to a different population, different methods, other languages and tools, different domains or different application sizes.

Blogs para la enseñanza de literatura infantil y juvenil en español: espacio central de la LIJ 2.0

Para analizar la recepción de las obras de literatura infantil y juvenil en internet, los blogs continúan siendo un espacio fundamental para la opinión crítica, la reflexión académica y la práctica docente configurándose como eje central del concepto LIJ 2.0. Después de analizar dicho concepto, se presentarán en primer lugar los principales blogs de la LIJ en castellano, donde encontramos espacios de escritores e ilustradores, propuestas de animación a la lectura, repositorios de obras y crítica literaria, centrándonos más en la parte de difusión y animación a la lectura que en la de creación literaria. Posteriormente se presentarán el recorrido didáctico realizado a lo largo de cinco años en la Universidad de Alicante para explotar dichas herramientas en distintos niveles educativos.

Competències mediàtiques a l’IES Dr. Balmis d’Alacant

La introducció de les TIC en l’ensenyament (les TAC) planteja molts interrogants entre els membres de la comunitat educativa, especialment entre el professorat. L’atracció del mitjà per als aprenents, la manca de reflexió en l’ús, tant per part del professorat com de l’alumnat, la necessitat d’una formació específica, l’adequació de les infraestructures al concepte i a les possibilitats que ofereix el web 2.0 i la incorporació de les aplicacions TAC en les programacions d’aula són alguns aspectes que mereixen una atenció específica i una anàlisi detinguda. La base de gran part de les respostes rau en una planificació eficaç de la formació del professorat que satisfaça les expectatives de tothom. Els projectes de centre, la utilització de plataformes educatives com Moodle i l’autoformació són sendes que ens acosten envers les solucions. En aquest treball, hi centrem l’atenció en les valoracions, les pràctiques habituals, les actituds i els coneixements relacionats amb la competència mediàtica o digital del professorat de l’IES Dr. Balmis d’Alacant. Ens basem en una enquesta realitzada en línia que aplega aquests continguts en una combinació d’ítems de resposta tancada i d’altres de resposta oberta.

De las tabletas a los MOOC en la LIJ 2.0 y la didáctica de lengua y literatura

Según los Informes Horizon 2013 y 2014 para la educación superior y para la etapa escolar, la programación en la nube, los cursos masivos abiertos en línea y el trabajo con tabletas y aplicaciones móviles serán las tendencias principales de los próximos años en tecnología educativa. Las tabletas y sus aplicaciones han entrado en todos los niveles educativos y ya es habitual verlas en cualquier clase por lo que es imprescindible conocer sus posibilidades para sacarles el máximo rendimiento. Además la Universidad de Alicante se ha convertido en referente en el diseño de MOOC con Unimooc como modelo pionero y XarxaMOOC como buque insignia en el ámbito lingüístico. Desde el área de didáctica de la lengua y la literatura y para reforzar el concepto LIJ 2.0 (lectura y literatura infantil y juvenil en la web social) queremos profundizar en ambos conceptos, presentar una breve panorámica y hacer un resumido estudio de casos para proponer una serie de ejemplos y herramientas que nos sean útiles en el futuro.

Facebook in teaching: strengths and weaknesses

Purpose – The use of online social networks has experienced a vertiginous increase in the last few years, and young people appear as the key players in this trend. Immersed, educated and raised in the middle of technology, the new student generation is one of digital natives. Instead, lecturers are digital immigrants, but the authors have the responsibility to turn a technology which can be a distraction into a teaching tool. Facebook is an example of Web 2.0 technology that owns a huge potential in the field of education. The purpose of this paper is to show the teaching experience with the Facebook social network in human resource management degree subjects, for the purpose of highlighting its strengths and weaknesses. Design/methodology/approach – A survey was carried out among university students in order to reach the goal. A total of 191 students were asked to give their opinion about the use of Facebook in teaching, achieving 125 valid answers. Findings – Facebook can positively impact on the performance of students, who are satisfied with the experience and think that the information obtained in Facebook can improve their training. More negative attitudes towards Facebook appeared among those students who had not used it. Originality/value – The paper summarises the strengths and weaknesses of Facebook through a literature review and assesses them via a survey.

Spanish Nursing Students' Practical Experience of Computer Applications in Nursing

This study aimed to determine the level of computer practical experience in a sample of Spanish nursing students. Each student was given a Spanish language questionnaire, modified from an original used previously with medical students at the Medical School of North Carolina University (USA) and also at the Education Unit of Hospital General Universitario del Mar (Spain). The 10-item self-report questionnaire probed for information about practical experience with computers. A total of 126 students made up the sample. The majority were female (80.2%; n=101). The results showed that just over half (57.1%, n=72) of the students had used a computer game (three or more times before), and that only one third (37.3%, n=47) had the experience of using a word processing package. Moreover, other applications and IT-based facilities (e.g. statistical packages, e-mail, databases, CD-ROM searches, programming languages and computer-assisted learning) had never been used by the majority of students. The student nurses' practical experience was less than that reported for medical students in previous studies.

Literatura infantil y juvenil en Internet. De la Cervantes Virtual a la LIJ 2.0. Herramientas y espacios para su estudio y difusión

Internet se ha convertido en un espacio central para el estudio y la difusión de la Literatura Infantil y Juvenil (LIJ). En la red encontramos dos modelos distintos, la sección de LIJ (BLIJ) de la Biblioteca Virtual Miguel de Cervantes y los espacios de la Web Social, como los blogs, los wikis o las redes sociales, englobados en el concepto LIJ 2.0 (Literatura y Lectura Infantil y Juvenil). En esta investigación se hace un análisis de ambos modelos planteando distintas maneras de integración y de explotación didáctica.