Age determination and stable isotope record of planktonic foraminifera from sediments of the Baffin Shelf

Stable isotopic values on planktonic foraminifera in a suite of cores from basins across the SE Baffin Shelf are used to extract a record of meltwater events during Termination I deglaciation. Resolution and Hatton basins lie on the SE Baffin Shelf at water depths > 500 m, seaward of major conduits for ice drainage from the eastern sector of the Laurentide Ice Sheet (LIS). Accelerator mass spectrometry 14C dates are used to constrain our chronology of events in ten cores. In Resolution Basin, three cores have 14C AMS dates on foraminifera of > 20 ka at their bases; whereas Hatton Basin cores terminate in sediments < 13 kyr. Sedimentation rates varied between 0.1 to 4.5 m/ka. Stable oxygen and carbon isotopic ratios were obtained on 146 samples of the planktonic foraminifera Neogloboquadrina pachyderma (Ehrenberg) sinistral, from seven of the ten cores. No evidence was found to indicate that test morphology or size affected delta18O. Between 7 and 13.5 ka the surface water on the shelf was on average 1 per mil lower than the open ocean signal. Significant temporal variations were found in both delta18O and delta13C. Evidence for significant low delta18O events occurred between 13 and 8 ka. The delta13C record from the planktonic foraminifera suggests a threefold division of events between 13 and 7 ka, with positive values between 10.8 and 13.0 ka, negative values between 9 and 10.8 ka, and positive values from 7 to 9 ka. The delta18O data suggest the presence of meltwater on the shelf some 3,000 years prior to the first late glacial dates on terrestrial deglaciation (at circa 10.4 ka). "Hudson Strait must be the real key to the importance of the calving process during deglaciation, because it is potentially the largest marine outlet for the Laurentide Ice Sheet and because it leads into the very center of the ice sheet.....the rates of calving through Hudson Strait during the period of initial ?18O rise unfortunately are unknown." W. F. Ruddiman (1987, p. 151)

Oxygen and hydrogen isotopes measured in the Northeast Atlantic

Only a few studies have examined the variation of oxygen and hydrogen isotopes of seawater in NE Atlantic water masses, and data are especially sparse for intermediate and deep-water masses. The current study greatly expands this record with 527 d18O values from 47 stations located throughout the mid- to low-latitude NE Atlantic. In addition, dD was analyzed in the 192 samples collected along the GEOTRACES North Atlantic Transect GA03 (GA03_e=KN199-4) and the 115 Iberia-Forams cruise samples from the western and southern Iberian margin. An intercomparison study between the two stable isotope measurement techniques (cavity ring-down laser spectroscopy and magnetic-sector isotope ratio mass spectrometry) used to analyze GA03_e samples reveals relatively good agreement for both hydrogen and oxygen isotope ratios. The surface (0-100 m) and central (100-500 m) water isotope data show the typical, evaporation related trend of increasing values equatorward with the exception for the zonal transect off Cape Blanc, NW Africa. Off Cape Blanc, surface water isotope signatures are modified by the upwelling of fresher Antarctic Intermediate Water (AAIW) that generally has isotopic values of 0.0 to 0.5 per mil for d18O and 0 to 2 per mil for dD. Along the Iberian margin the Mediterranean Outflow Water (MOW) is clearly distinguished by its high d18O (0.5-1.1 per mil) and dD (3-6 per mil) values that can be traced into the open Atlantic. Isotopic values in the NE Atlantic Deep Water (NEADW) are relatively low (d18O: -0.1 to 0.5 per mil; dD: -1 to 4 per mil) and show a broader range than observed previously in the northern and southern convection areas. The NEADW is best observed at GA03_e Stations 5 and 7 in the central NE Atlantic basin. Antarctic Bottom Water isotope values are relatively high indicating modification of the original Antarctic source water along the flow path. The reconstructed d18O-salinity relationship for the complete data set has a slope of 0.51, i.e., slightly steeper than the 0.46 described previously by Pierre et al. (1994, J. Mar. Syst. 5 (2), 159-170.) for the tropical to subtropical Northeast Atlantic. This slope decreases to 0.46 for the subtropical North Atlantic Central Water (NACW) and the MOW and to 0.32 for the surface waters of the upper 50 m. The dD-salinity mixing lines have estimated slopes of 3.01 for the complete data, 1.26 for the MOW, 3.47 for the NACW, and 2.63 for the surface waters. The slopes of the d18O-dD relationship are significantly lower than the one for the Global Meteoric Water Line with 5.6 for the complete data set, 2.30 for the MOW, 4.79 for the NACW, and 3.99 for the surface waters. The lower slopes in all the relationships clearly reflect the impact of the evaporation surplus in the subtropics.

Evaluation of Non-Survey International IO Construction Methods with the Asian-Pacific Input-Output Table

This paper presents four non-survey methods to construct a full-information international input-output table from national IO tables and international import and export statistics, and this paper tests these four methods against the semi-survey international IO table for nine East-Asian countries and the USA, which is constructed by the Institute of Developing Economies in Japan. The tests show that the impact on the domestic flows of using self-sufficiency ratios is small, except for Singapore and Malaysia, two countries with large volumes of smuggling and transit trade. As regards the accuracy of the international flows, all methods show considerable errors, of 10%-40% for commodities and of 10%-70% for services. When more information is added, i.e. going from Method 1 to 4, the accuracy increases, except for Method 2 that generally produces larger errors than Method 1. In all, it seems doubtful whether replacing the semi-survey Asian-Pacific IO table with one of the four non-survey tables is justified, except when the semi-survey table itself is also considered to be just another estimate.

Criterios de calidad del servicio prestado en el ámbito de la línea de atraque de las terminales portuarias de contenedores

Esta Tesis Doctoral evalúa empíricamente la calidad del servicio en la línea de atraque de las terminales portuarias de contenedores. La metodología propuesta utiliza indicadores de calidad y se basa en el concepto de la segmentación de servicio. Para ello se desarrolla la teoría del Control Estadístico de Procesos (CEP) y se utilizan los gráficos de control para clasificar el servicio en las terminales de contenedores. El propósito de la Tesis es proporcionar una metodología basada en el Control Estadístico de Procesos (CEP) para evaluar la calidad del servicio y detectar las escalas de un servicio regular de línea que se encuentran fuera de control. Por tanto, la metodología se puede utilizar para detectar eventos que son indicativos de cambio real del proceso en la línea de atraque. Esta detección puede ser compleja pues las características de los procesos en terminales de contenedores son variables. La metodología proporciona mediante los gráficos de control criterios estadísticamente objetivos de cambio. Cuando el cambio es detectado y considerado bueno sus causas deben ser identificadas y posiblemente convertirse en la nueva forma de trabajar, cuando el cambio es negativo, entonces sus causas deberían ser identificadas y eliminadas. La Tesis Doctoral está organizado de la siguiente manera: La primera parte es la introducción, e incluye los capítulos 1 al 4, la segunda parte presenta el Estado del Arte (capítulo 5) y algunos de los estudios que han inspirado esta investigación, la tercera parte se centra en la metodología utilizada (capítulo 6) y su aplicación sobre un caso de estudio (capítulo 7). Finalmente, en la cuarta parte se presentan las conclusiones y se proponen algunas de las nuevas líneas de investigación que quedan abiertas (capítulo 8). This Thesis empirically evaluates the quality of service in the berthing face of container terminals. The methodology proposed is focused on quality of service indicators and is based on the concept of service segmentation. The Statistical Process Control (SPC) theory and the control charts are used to classify container terminal service. The aim of this Thesis is to provide a methodology based on Statistical Process Control that can evaluate the quality of service and also can detect scales of shipping liner service that are out of control. Therefore, the methodology can be used to detect events that are indicative of real change in the berthing process of container vessels. The methodology proposed allows simple detection of events that are indicative of actual process change in container terminals. This detection is complex because the characteristics of the processes are variable in the container terminals; the control chart provides statistically objective criteria of change. When change is detected and considered good its cause should be identified and possibly become the new way of working, where the change is bad then its cause should be identified and eliminated. This Thesis is organized as follows: The first part is the introduction (includes Chapters 1 to 4), the second part presents the State of the Art (Chapter 5) and some of the studies that have inspired this research. The third part focuses on the methodology used (Chapter 6) and its application to a case study (Chapter 7). Finally, Part 4 presents the conclusions and suggests future research (Chapter 8).

La participación de los jóvenes universitarios en la planificación urbana. Estudios de caso de Lisboa, Madrid y Fortaleza

La participación de los jóvenes en los procesos de planificación urbana en Lisboa, Madrid y Fortaleza ha sido tema central de la presente tesis. Los principales objetivos perseguidos consisten en: caracterizar y analizar críticamente las dimensiones más importantes de la participación de jóvenes universitarios en los procesos participativos; aportar características de interés juvenil para un “modelo” de planificación urbana; elaborar directrices para el diseño de actuaciones en un proceso urbano participativo desde la perspectiva de los jóvenes; establecer el alcance de un instrumento urbano participativo reglamentado por el gobierno local entre los jóvenes; determinar si la percepción de los jóvenes universitarios acerca de las acciones del gobierno local tiene influencia en los procesos participativos. El universo estadístico de la muestra lo conforman la totalidad de 737 jóvenes universitarios encuestados en Lisboa, Madrid y Fortaleza. Que se distribuye en 104 encuestados en Lisboa, 329 en Madrid, y 304 en la ciudad de Fortaleza. El cuestionario contiene preguntas: abiertas, cerradas y mixtas. La mayor parte de las cuestiones son cerradas, y en cuanto a las opciones de respuesta: en muchas preguntas se ha aplicado, una escala tipo Likert, entre 1 y 4, siendo 4 el grado más alto (totalmente de acuerdo), y 1 el grado más bajo (nada de acuerdo), y para otras, una opción múltiple, con solamente una opción de respuesta. Se realizó un cuestionario de 31 preguntas en Lisboa, y tras su aplicación y obtención de resultados se revisó y mejoró obteniendo un cuestionario de 23 preguntas que fue aplicado en Madrid y Fortaleza. Se realizan análisis descriptivos, y algún análisis factorial en diversas preguntas del cuestionario, y se estudian diferencias en función de las variables sociodemográficas planteadas. Los resultados constatan que es muy baja la participación en los procesos institucionalizados por el gobierno local, en contrapartida es bastante alta en los procesos organizados por los ciudadanos. La información limita la participación de los jóvenes y ya que estos reconocen como motivación estar más y mejor informados y controlar y acompañar las acciones de su gobierno local. Por otra parte, desean participar en grupo en foros y debates presenciales. Los jóvenes madrileños consideran que las etapas más importantes en un proceso urbano participativo son: información, seguimiento y evaluación, mientras que para los jóvenes de Fortaleza son: Fiscalización, concienciación e información. Se ha verificado que desde la percepción de los jóvenes de Lisboa los ciudadanos son consultados en los procesos urbanos participativos y de acuerdo con los jóvenes de Madrid y Fortaleza los ciudadanos son dirigidos, influenciados y manipulados. Los problemas de carácter urbano no tienen una conceptualización clara y precisa entre los jóvenes universitarios y los problemas urbanos que más afectan la vida de los jóvenes universitarios son aparcamientos, contaminación y seguridad urbana. Sin embargo, los transportes son apuntados por los jóvenes universitarios de Lisboa, Madrid y Fortaleza. Además no saben identificar los problemas de su barrio. Así como de las causas y consecuencias y soluciones de los problemas urbanos. Eligen como mejor estrategia para desarrollar un proceso urbano participativo el acuerdo entre técnicos, población y el gobierno local. Los jóvenes universitarios de Fortaleza apuntan directrices para una planificación urbana con énfasis en la seguridad urbana, la sostenibilidad y la investigación, tecnología e innovación. Por otro lado, los jóvenes universitarios de Madrid perfilan tres “modelos” de planificación urbana: un “Modelo” socio-económica, un “Modelo” sostenible e innovadora y un “Modelo” de Planificación Urbana con énfasis en espacios públicos, entretenimiento, seguridad urbana y deporte. Los jóvenes universitarios rechazan la idea que la planificación urbana lleva en cuenta sus perspectivas y opiniones. Respeto al Presupuesto Participativo, el alcance de dicho proceso entre los jóvenes universitarios es extremamente bajo. Sin embargo, opinan que la aproximación entre ciudadanos, técnicos y gobierno en los procesos de Presupuesto Participativo mejora la rendición de cuentas. Además los jóvenes creen que dichos procesos conceden un poder moderado a los ciudadanos, y consideran que el poder concedido en los procesos urbanos influye directamente en el interés y empeño en participar. ABSTRACT Youth participation in urban planning processes in Lisbon, Madrid and Fortaleza is the main subject of this thesis. Our key goals are the following: characterising and critically analysing the most important dimensions of young university students’ participation in participative processes; providing features of interest for the young for an urban planning “model”; developing a variety of guidelines for designing actions in a participative urban process from the perspective of young people; analysing the impact upon the young of a participative urban instrument implemented by the local government; determining whether young university students’ perception of local government actions influences participative processes. The statistical universe of the sample comprises a total of 737 young university students who were surveyed in Lisbon, Madrid and Fortaleza, distributed as follows: 104 respondents in Lisbon, 329 in Madrid, and 304 in Fortaleza. The survey is made up of open-ended, closed-ended and mixed questions. Most questions are closed-ended. Regarding the answer options, a Likert-type scale has been used in many questions. The scale ranges from 1 to 4, 4 being the highest value (completely agree) and 1 the lowest (completely disagree). Besides, there are multiple-choice questions with only one possible answer. A 31- question survey was conducted in Lisbon. After the survey was run and the results were obtained, it was reviewed and improved. The improved version was a 23- question survey which was conducted in Madrid and Fortaleza. Descriptive analyses as well as some factorial analyses are carried out in several questions, and differences are studied depending on the socio-demographic variables involved. The results show that participation in processes implemented by local governments is very low. In contrast, participation is quite high in processes organised by citizens. Information limits youth participation, as young people point out that they are motivated by more and better information and by the possibility of monitoring and keeping track of their local government actions. They also wish to take part in face-to-face group forums and discussions. Young people from Madrid think that the most important stages in participative urban processes are information, follow-up and assessment, whereas young people from Fortaleza highlight tax matters, awareness and information. It has been confirmed that Lisbon youth perceive that citizens are consulted in participative urban processes. Youth from Madrid and Fortaleza, on the other hand, state that citizens are directed, influenced and manipulated. Young university students do not have a clear, precise concept of urban problems. Among these, they are most affected by car parks, pollution and urban safety, but the transport problem is pointed out by young university students from Lisbon, Madrid and Fortaleza. Furthermore, they cannot identify the problems in their neighbourhoods, nor are they able to specify the causes, consequences and solutions of urban problems. Their preferred strategy for developing a participative urban process is an agreement between technicians, the population and the local government. Young university students from Fortaleza suggest guidelines for an urban planning approach emphasising urban safety, sustainability and research, technology and innovation. Those from Madrid, for their part, outline three urban planning “models”: a socioeconomic “model”, a sustainable and innovative “model”, and an urban planning “model” with a focus on public areas, entertainment, urban safety and sport. Young university students disagree that urban planning takes their perspectives and views into account. Moreover, the impact of the Participative Budget upon their lives is extremely low. In their opinion, however, closer collaboration between citizens, technicians and governments in Participative Budget processes promotes accountability. The young also think that these processes give moderate power to citizens, and in their view the power that can be exerted in urban processes directly influences the interest in participating and the will to do so.

Folding and activity of circularly permuted forms of a polytopic membrane protein

The transmembrane subunit of the Glc transporter (IICBGlc), which mediates uptake and concomitant phosphorylation of glucose, spans the membrane eight times. Variants of IICBGlc with the native N and C termini joined and new N and C termini in the periplasmic and cytoplasmic surface loops were expressed in Escherichia coli. In vivo transport/in vitro phosphotransferase activities of the circularly permuted variants with the termini in the periplasmic loops 1 to 4 were 35/58, 32/37, 0/3, and 0/0% of wild type, respectively. The activities of the variants with the termini in the cytoplasmic loops 1 to 3 were 0/25, 0/4 and 24/70, respectively. Fusion of alkaline phosphatase to the periplasmic C termini stabilized membrane integration and increased uptake and/or phosphorylation activities. These results suggest that internal signal anchor and stop transfer sequences can function as N-terminal signal sequences in a circularly permuted α-helical bundle protein and that the orientation of transmembrane segments is determined by the amino acid sequence and not by the sequential appearance during translation. Of the four IICBGlc variants with new termini in periplasmic loops, only the one with the discontinuity in loop 4 is inactive. The sequences of loop 4 and of the adjacent TM7 and TM8 are conserved in all phosphoenolpyruvate-dependent carbohydrate:phosphotransferase system transporters of the glucose family.

Regeneração hepática em animais jovens com estenose da veia porta ou ligadura da artéria hepática: estudos histológicos, moleculares e avaliação dos efeitos da insulina e do tacrolimus como agentes regenerativos

INTRODUÇÃO: O transplante hepático é o único tratamento efetivo para uma variedade de doenças hepáticas irreversíveis. No entanto, o número limitado de doadores pediátricos leva ao uso de enxertos hepáticos de doadores adultos, com necessidade de anastomoses vasculares mais complexas. Essas anastomoses tornam-se complicadas pela diferença no calibre dos vasos entre o doador e o receptor, resultando em alterações do fluxo sanguíneo, estenose da anastomose venosa ou arterial e trombose. Os efeitos para regeneração hepática decorrentes da privação do fluxo sanguíneo pela veia porta ou pela artéria hepática não estão completamente elucidados. Experimentalmente, quando um lobo do fígado não recebe o fluxo venoso portal, é observada atrofia deste segmento e hipertrofia do restante do órgão perfundido. Embora existam vários modelos experimentais para estudo da regeneração hepática, poucos são focados em animais em crescimento. Além disso, os efeitos regenerativos de drogas como o tacrolimus e a insulina precisam ser pesquisados, com o objetivo de encontrar um tratamento ideal para a insuficiência hepática ou um método de estimular a regeneração do fígado após ressecções ou transplantes parciais. O objetivo do presente estudo é descrever modelos de regeneração hepática em ratos em crescimento com: 1) ausência de fluxo hepático arterial e 2) redução do fluxo portal. Adicionalmente, o estudo avalia o efeito pró-regenerativo do tacrolimus e da insulina nesses modelos descritos. MÉTODOS: cento e vinte ratos (entre 50 e 100g de peso) foram divididos em 6 grupos, de acordo com o tipo de intervenção cirúrgica: Grupo 1, incisão abdominal sem intervenção hepática; Grupo 2, hepatectomia a 70%; Grupo 3, hepatectomia a 70% + estenose de veia porta; Grupo 4, hepatectomia a 70% + ligadura da artéria hepática; Grupo 5, hepatectomia a 70% + estenose de veia porta + insulina; Grupo 6, hepatectomia a 70% + estenose de veia porta + tacrolimus. Os animais dos grupos 1 ao 4 foram subdivididos em 5 subgrupos de acordo com o momento da morte: 1, 2, 3, 5 e 10 dias após a intervenção cirúrgica. Os animais dos grupos 5 e 6 foram subdividos em 2 subgrupos de acordo com o momento da morte: 2 e 10 dias após a intervenção cirúrgica. Os lobos hepáticos remanescentes foram submetidos à análise histomorfométrica, imuno-histoquímica e molecular. RESULTADOS: Verificou-se que no grupo com hepatectomia a 70% houve recuperação do peso do fígado no terceiro dia com aumento da atividade mitótica, enquanto que no grupo com estenose portal não se observou esse fenômeno (p < 0,001). A insulina e o tacrolimus promoveram aumento do peso do fígado e do índice mitótico. A atividade mitótica foi considerada aumentada nos animais dos grupos hepatectomia, hepatectomia + ligadura da artéria, insulina e tacrolimus; e esse parâmetro estava reduzido no grupo submetido à hepatectomia + estenose portal (p < 0,001). A expressão de interleucina 6 estava presente em todos os animais, sendo significativamente maior nos grupos hepatectomia, hepatectomia + ligadura da artéria e significativamente menor no grupo hepatectomia + estenose portal. Entretanto, a administração de tacrolimus ou insulina recuperou os níveis teciduais de interleucina 6 no grupo com estenose portal. CONCLUSÕES: No presente estudo foi padronizado um modelo simples e facilmente reprodutível para estudar a regeneração hepática em ratos em crescimento com redução do fluxo arterial ou venoso para o fígado. Foi demonstrado que a administração de insulina ou tacrolimus é capaz de reverter os efeitos deletérios da estenose portal na regeneração hepática. A obstrução do fluxo arterial não afetou a capacidade regenerativa hepática

Isotropic petroleum pitch as a carbon precursor for the preparation of activated carbons by KOH activation

Results show that it is possible to activate a low softening point isotropic petroleum pitch, without intermediate pre-treatments, by chemical activation with KOH. The chemical activation is carried out by direct heat treatment of a mixture of the isotropic pitch and KOH. It produces activated carbons (ACs) with micropore volumes as high as 1.12 cm3/g, and BET surface areas around 3000 m2/g. The activating agent/precursor ratios studied (from 1/1 to 4/1; wt./wt.) show, as expected, that increasing the ratio enhances the adsorption characteristics of the resulting AC.

Paleoceanography on sediment core MD01-2416

IMAGES core MD01-2416 (51°N, 168°E) provides the first centennial-scale multiproxy record of Holocene variation in North Pacific sea-surface temperature (SST), salinity, and biogenic productivity. Our results reveal a gradual decrease in subarctic SST by 3-5 °C from 11.1 to 4.2 ka and a stepwise long-term decrease in sea surface salinity (SSS) by 2-3 p.s.u. Early Holocene SSS were as high as in the modern subtropical Pacific. The steep halocline and stratification that is characteristic of the present-day subarctic North Pacific surface ocean is a fairly recent feature, developed as a product of mid-Holocene environmental change. High SSS matched a salient productivity maximum of biogenic opal during Bølling-to-Early Holocene times, reaching levels similar to those observed during preglacial times in the warm mid-Pliocene prior to 2.73 Ma. Similar productivity spikes marked every preceding glacial termination of the last 800 ka, indicating recurrent short-term events of mid-Pliocene-style intense upwelling of nutrient-rich Pacific Deepwater in the Pleistocene. Such events led to a repeated exposure of CO2-rich deepwater at the ocean surface facilitating a transient CO2 release to the atmosphere, but the timing and duration of these events repudiate a long-term influence of the subarctic North Pacific on global atmospheric CO2 concentration.

Absolute abundances of benthic foraminifers and stable isotopes from the Alvin dives 3709-3712

The presence of gas hydrates on the Blake Ridge diapir, northeastern Atlantic Ocean, offers an opportunity to study the impact of methane seepage on the ecology and geochemistry of benthic foraminifera in the late Holocene. Three push cores, covering a time span of ~ 1000 yrs, were retrieved from three distinct microhabitats at the top of the diapir at a water depth of ~ 2150 m: (i) sediments away from seepage (control core), (ii) sediments overlain by clusters of methanotrophic and thiotrophic bivalves, and (iii) chemoautotrophic microbial mats. The foraminiferal assemblages at the two seep sites are marked by a reduction in benthic foraminiferal species diversity, coupled with a near-absence of agglutinated species. However, an opportunistic population rise in CH4- or H2S-tolerant calcareous species (e.g., Globocassidulina subglobosa and Cassidulina laevigata) that utilize the abundant trophic resources at the seeps has led to an increase in the overall assemblage density there. The delta18O and delta13C values of three species of benthic foraminifera - Gyroidinoides laevigatus, Globocassidulina subglobosa, and Uvigerina peregrina - and the planktonic species Globorotalia menardii were acquired from all three cores. The benthic species from methane seeps yield delta13C values of 0.1 to - 4.2 (per mil VPDB), that are distinctly more 13C-depleted relative to the delta13C of 0.4 to - 1.0 (per mil VPDB) at the control (off seep) site. The species from a mussel-bed site exhibit more negative delta13C values than those from microbial mats, possibly reflecting different food sources and higher rate of anaerobic oxidation of methane. The positive delta13C values in the paired planktonic species suggest that authigenic carbonate precipitation did not overprint the observed 13C depletions. Hence the probable cause of negative delta13C of benthic foraminifera is primary calcification from Dissolved Inorganic Carbon (DIC) containing mixed carbon fractions from (a) highly 13C-depleted, microbially-oxidized methane and (b) a seawater source.

Notes on map reading, 1929.

Reprinted in Canada (with amendments 1 to 4) October, 1939, by permission of the Controller, His Majesty's Stationery Office.

Quantifying ice-shelf basal melt and ice-stream dynamics using high-resolution DEM and GPS time series

Thesis (Ph.D.)--University of Washington, 2016-06

Selective approach for transperitoneal and extraperitoneal endoscopic nephrectomy in children

Purpose: From the experience of a large combined series of transperitoneal. (TP) and retroperitoneal (RP) endoscopic complete and partial nephroureterectornies in children, we present a logical selective endoscopic approach to benign renal pathology. Materials and Methods: During a 5-year period 122 complete nephrectomies and nephroureterectomies (bilateral 2, invisible ectopic 8) and 63 partial nephroureterectomies for duplex (52 upper, 8 lower) or singleton polar disease (xanthogranulomatous pyelonephritis 1, cyst 2) were performed. Of the partial nephrectomies, ureterectomy, bladder repair and lower moiety reimplantation were performed in 8. Patient age ranged from 2.7 months to 14 years (mean 2.9 years). Preoperative weight ranged from 2.7 to 98 kg (mean 12.3). The position of the renal remnant, the presence or absence of a refluxing ureter and the need for ureterectomy were the major determining factors affecting choice of endoscopic approach. Results: A total of 179 (96.7%) procedures were successfully completed endoscopically. The 6 open conversions (3.2%) occurred early in our experience. The operating time reflected the complexity of the excision and lower urinary reconstruction (lateral and posterior RP 25 to 145 minutes [mean 921) TP with ureterocelectomy and bladder neck repair 105 to 355 minutes [mean 153]. Hospital stay for RP and simple TP was 1.5 days (mean 1 to 4) and for complicated TP 2 to 8 days (mean 3.5). Conclusions: We suggest a posterior retroperitoneal approach with isolated renal excision without extended ureterectomy. The lateral retroperitoneal approach allows complete ureterectomy as well as better exposure to horseshoe and pelvic kidneys and, therefore, avoids exposure to intraperitoneal. structures. Finally, the transperitoneal approach is recommended when complete moiety excision with lower urinary reconstruction is anticipated.

The rural medicine rotation: Increasing rural recruitment through quality undergraduate rural experiences

TITLE: The Rural Medicine Rotation: Increasing Rural Recruitment through Quality Undergraduate Rural Experiences Eley Diann, University of Queensland, School of Medicine, Rural Clinical Division, Toowoomba 4350, Queensland Australia Baker Peter, University of Queensland, School of Medicine Rural, Clinical Division, Toowoomba 4350, Queensland Australia Chater Bruce, University of Queensland, Chair, Clinical School Management Committee, School of Medicine Rural Clinical Division, Queensland Australia CONTEXT: While rural background and rural exposure during medical training increases the likelihood of rural recruitment (Wilkinson, 2003), the quality and content of that exposure is the key to altering undergraduatesâ?? perceptions of rural practice. The Rural Clinical Division at University of Queensland (UQ) runs the Rural Medicine Rotation (RMR) within the School of Medicine. The RMR is one of five eight week clinical rotations in Year three and is compulsory for all students. The RMR provides the opportunity to learn from a wide range of health professionals and clinical exposure is not restricted to general practice but also includes remote area nursing, Indigenous health care, allied health professionals and medical specialists. Week 1 involves preparation for their rural placement with workshops and seminars and Week 8 consolidates their placement and includes case and project presentations and a summative assessment. Weeks 2-7 are spent living and working as part of the health team in different rural communities. SETTING: Rural communities in and around Queensland including locations such as Arnham Land, Thursday Island, Mt. Isa and Alice Springs METHOD: All aspects of the RMR are evaluated with surveys using both qualitative and quantitative free response questions, completed by all students at the end of the Week 8. RESULTS: Overall the RMR is evaluated highly and narratives offered by students show that the RMR provides a positive rural experience. The overall impact of the RMR for students in 2004 ranked 3.45 on a scale of 1 to 4 (1 = lowest and 4 = highest), and is exemplified by the following quote; â??I enjoyed my placement so much I am now considering rural medicine something I definitely had not considered beforeâ??. OUTCOME: The positive impact of the RMR on studentâ??s perceptions of rural medicine is encouraging and can help achieve the overall aim of increasing recruitment of the rural workforce in Australia.

The verbal transformation effect:an exploration of the perceptual organization of speech

Six experiments investigated the influence of several grouping cues within the framework of the Verbal Transformation Effect (VTE, Experiments 1 to 4) and Phonemic Transformation Effect (PTE, Experiments 5 and 6), where listening to a repeated word (VTE) or sequence of vowels (PTE) produces verbal transformations (VTs). In Experiment 1, the influence of F0 frequency and lateralization cues (ITDs) was investigated in terms of the pattern of VTs. As the lateralization difference increased between two repeating sequences, the number of forms was significantly reduced with the fewest forms reported in the dichotic condition. Experiment 2 explored whether or not propensity to report more VTs on high pitch was due to the task demands of monitoring two sequences at once. The number of VTs reported was higher when listeners were asked to attend to one sequence only, suggesting smaller attentional constraints on the task requirements. In Experiment 3, consonant-vowel transitions were edited out from two sets of six stimuli words with ‘strong’ and ‘weak’ formant transitions, respectively. Listeners reported more forms in the spliced-out than in the unedited case for the strong-transition words, but not for those with weak transitions. A similar trend was observed for the F0 contour manipulation used in Experiment 4 where listeners reported more VTs and forms for words following a discontinuous F0 contour. In Experiments 5 and 6, the role of F0 frequency and ITD cues was investigated further using a related phenomenon – the PTE. Although these manipulations had relatively little effect on the number of VTs and forms reported, they did influence the particular forms heard. In summary, the current experiments confirmed that it is possible to successfully investigate auditory grouping cues within the VTE framework and that, in agreement with recent studies, the results can be attributed to the perceptual re-grouping of speech sounds.