Endogeneous matching in university-industry collaboration: Theory and empirical evidence from the UK

We develop a two-sided matching model to analyze collaboration between heterogeneousacademics and firms. We predict a positive assortative matching in terms of both scientificability and affinity for type of research, but negative assortative in terms of ability on one sideand affinity in the other. In addition, the most able and most applied academics and the mostable and most basic firms shall collaborate rather than stay independent. Our predictionsreceive strong support from the analysis of the teams of academics and firms that proposeresearch projects to the UK's Engineering and Physical Sciences Research Council.

Población de "Marucha" donax marincovichi (COAN 1983) en bahía Samanco, Región Áncash, Perú. Invierno 2006

Estudia la población de marucha, con la finalidad de determinar la población, distribución y algunos aspectos biológicos.

Crucero BIC Humboldt 8301, del callao a Puerto Pizarro. Exploración biológico pesquera. 12 - 24 enero 1983

Para conocer las condiciones biológicas de los recursos demersales y pelágicos en la plataforma continental del norte del Perú se realizó un crucero de investigación a bordo del BIC Humboldt con el objeto de determinar el impacto de El Niño en los patrones de distribución y abundancia de los principales recursos ícticos.

Evaluation par des médecins installés de l'efficacité antihypertensive de la débrisoquine, de la méthyldopa et du propranolol [Evaluation by practicing physicians of the antihypertensive efficacy of debrisoquin, methyldopa and propranolol]

The antihypertensive effect of debrisoquine (20 mg/day), methyldopa (100 mg/day) and propranolol (160 mg/day) was compared to that obtained with a placebo in a controlled trial carried out by a group of 14 internists. Forty-eight patients with uncomplicated essential hypertension were included. Mefruside (25 mg/day) was first given alone for 6 weeks ("open phase" of the trial) and to this diuretic was then added in double-blind fashion and randomized sequence a placebo or an active drug. Each of the 4 blind phases lasted 4 weeks. At the end of the "open phase", blood pressure in seated position averaged 168/111 +/- 19.6/13.5 mm Hg (mean +/- SD). A significant blood pressure decrease was observed after 4 weeks of treatment with the placebo as well as with the investigated compounds. With the placebo blood pressure was reduced to 158/102 +/- 19.6/13.5 mm Hg (p less than 0.001). The magnitude of the additional blood pressure decrease induced by the active drugs was relatively small and varied from 4 (debrisoquine) to 10 mm Hg (methyldopa, p less than 0.01) for the systolic and from 3 (debrisoquine, p less than 0.05) to 5 mm Hg (propranolol, p less than 0.05) for the diastolic. The percentage of patients with systolic pressure of less than or equal to 140 mm Hg and with diastolic pressure of less than 90 mm Hg during administration of either drug was not greater than 40 to 20% respectively. Propranolol appeared to be better tolerated than the other antihypertensive agents. These rather disappointing blood pressure results suggest that the efficacy of antihypertensive agents in private practice cannot be extrapolated from studies carried out in specialized hypertension clinics.

Distribución horizontal de los Amphipoda (crustacea) en el mar peruano durante el fenómeno "El niño" verano 1983

Los anfípodos hepéridos son microcrustáceos marinos que tienen un rol importante en la ecología trófica de especies pesqueras, se caracterizan por su voraz comportamiento predador sobre otros componentes del zooplancton (NELSON, 1979) y debido a su abundancia constituyen una fuente de alimento para niveles tróficos superiores (ALVAREZ y VIÑAS, 1994). El área de estudio comprende desde 03°29.80´S hasta los 12°54.50´S, abarcando los perfiles de Puerto Pizarro, Cabo Blanco, Talara, Paita, Punta Falsa, Pimentel, Chicama, Salaverry, Chimbote, Huarmey, Supe, Guacho, Chancay, Callao, Pucusana y Cerro Azul, cubriendo de esta manera la parte norte y centro del litoral peruano hasta las 100 millas náuticas de la costa y 50 metros de profundidad. Se determinan 34 especies de anfípodos, con 26 nuevos registros para el país y 2 especies nuevas. La familia Hyperridae es la que registra mayor representatividad a nivel específico destacando por su abundancia las especies Hyperioides sibaginis e Hyperietta vossleri. El presente trabajo, contribuye principalmente a ampliar el conocimiento de especies de anfípodos y asociarlas con las características ambientales, así las especies Vibilia chuni, Partaphronima gracilis, Hemithiphys tenuimanuss, Euscelus robustus y Schizoscelus ornatus, se encuentran relacionados con salinidades que fluctuan entre 34.8 y 35.1‰ y temperaturas de 25.4 hasta 28.2°C, rangos correspondientes a aguas de mezcla de Aguas Ecuatoriales Superficiales (AES) y Aguas Subtropicales superficiales (ASS).

Governor's Task Force on Efficiencies and Cost-Effectiveness in Iowa State Government,Final Report, December 1983

A special task force was formed and worked through its various committees to uncover and investigate possible areas for cutting costs and saving money in State Government operations. A total of 81 recommendations are made in this report, with potential savings of over $32 million during the next several years.

Addiction: l'égalité face aux substances [Addiction: are women and men equal?]

When illicit drugs are taken, men and women have a different biological response to drug used. Likewise, gender differences show more stigmas, more complex familial environment, and more history of sexual abuse for drug addicted women. The expression of psychiatric co-morbidities differs according to gender, with increased mood disorders, eating disorders, anxiety, and post traumatic disorders among drug addicted women.

Bortezomib(Velcade (R))-Thalidomide-Dexamethasone (VTD) Is Superior to Thalidomide-Dexamethasone (TD) In Patients with Multiple Myeloma (MM) Progressing or Relapsing After Autologous Transplantation.

Introduction: The Thalidomide-Dexamethasone (TD) regimen has provided encouraging results in relapsed MM. To improve results, bortezomib (Velcade) has been added to the combination in previous phase II studies, the so called VTD regimen. In January 2006, the European Group for Blood and Marrow Transplantation (EBMT) and the Intergroupe Francophone du Myélome (IFM) initiated a prospective, randomized, parallel-group, open-label phase III, multicenter study, comparing VTD (arm A) with TD (arm B) for MM patients progressing or relapsing after autologous transplantation. Patients and Methods: Inclusion criteria: patients in first progression or relapse after at least one autologous transplantation, including those who had received bortezomib or thalidomide before transplant. Exclusion criteria: subjects with neuropathy above grade 1 or non secretory MM. Primary study end point was time to progression (TTP). Secondary end points included safety, response rate, progression-free survival (PFS) and overall survival (OS). Treatment was scheduled as follows: bortezomib 1.3 mg/m2 was given as an i.v bolus on Days 1, 4, 8 and 11 followed by a 10-Day rest period (days 12 to 21) for 8 cycles (6 months) and then on Days 1, 8, 15, 22 followed by a 20-Day rest period (days 23 to 42) for 4 cycles (6 months). In both arms, thalidomide was scheduled at 200 mg/Day orally for one year and dexamethasone 40 mg/Day orally four days every three weeks for one year. Patients reaching remission could proceed to a new stem cell harvest. However, transplantation, either autologous or allogeneic, could only be performed in patients who completed the planned one year treatment period. Response was assessed by EBMT criteria, with additional category of near complete remission (nCR). Adverse events were graded by the NCI-CTCAE, Version 3.0.The trial was based on a group sequential design, with 4 planned interim analyses and one final analysis that allowed stopping for efficacy as well as futility. The overall alpha and power were set equal to 0.025 and 0.90 respectively. The test for decision making was based on the comparison in terms of the ratio of the cause-specific hazards of relapse/progression, estimated in a Cox model stratified on the number of previous autologous transplantations. Relapse/progression cumulative incidence was estimated using the proper nonparametric estimator, the comparison was done by the Gray test. PFS and OS probabilities were estimated by the Kaplan-Meier curves, the comparison was performed by the Log-Rank test. An interim safety analysis was performed when the first hundred patients had been included. The safety committee recommended to continue the trial. Results: As of 1st July 2010, 269 patients had been enrolled in the study, 139 in France (IFM 2005-04 study), 21 in Italy, 38 in Germany, 19 in Switzerland (a SAKK study), 23 in Belgium, 8 in Austria, 8 in the Czech republic, 11 in Hungary, 1 in the UK and 1 in Israel. One hundred and sixty nine patients were males and 100 females; the median age was 61 yrs (range 29-76). One hundred and thirty six patients were randomized to receive VTD and 133 to receive TD. The current analysis is based on 246 patients (124 in arm A, 122 in arm B) included in the second interim analysis, carried out when 134 events were observed. Following this analysis, the trial was stopped because of significant superiority of VTD over TD. The remaining patients were too premature to contribute to the analysis. The number of previous autologous transplants was one in 63 vs 60 and two or more in 61 vs 62 patients in arm A vs B respectively. The median follow-up was 25 months. The median TTP was 20 months vs 15 months respectively in arm A and B, with cumulative incidence of relapse/progression at 2 years equal to 52% (95% CI: 42%-64%) vs 70% (95% CI: 61%-81%) (p=0.0004, Gray test). The same superiority of arm A was also observed when stratifying on the number of previous autologous transplantations. At 2 years, PFS was 39% (95% CI: 30%-51%) vs 23% (95% CI: 16%-34%) (A vs B, p=0.0006, Log-Rank test). OS in the first two years was comparable in the two groups. Conclusion: VTD resulted in significantly longer TTP and PFS in patients relapsing after ASCT. Analysis of response and safety data are on going and results will be presented at the meeting. Protocol EU-DRACT number: 2005-001628-35.

Anàlisi quantitatiu de la paraula i de la imatge en els programes informatius de televisió. Estudi del cas de L’Informatiu de TVE a Catalunya (1983-2003)

Televisió Espanyola va començar la producció de programes a Catalunya amb la inauguració del estudis de Miramar el dia 14 de juliol de1959. El primer programa emès des d’aquest centre va ser realitzat als jardins de l’edifici i presentat per José Luis Barcelona. Era l’inici d’una història que ha superat ja el cinquantè aniversari i de la qual encara queden moltes coses per conèixer i per explicar. Tota la programació dels primers anys era en llengua castellana, fins la primera emissió de televisió en català, el 27 d'octubre de 1964. Va ser el punt de partida de molts anys de programes en català. Un dels valors que aporta TVE a Catalunya és la contribució als informatius d’àmbit estatal. És en aquesta especialitat dels programes d’informació que tant Miramar com Sant Cugat tenen una llarga experiència. Un indicador per estudiar aquest camí llarg i no sempre fàcil de les emissions de TVE des de Catalunya i en llengua catalana pot ser l’anàlisi de l’evolució dels informatius al llarg del temps. Aspectes com l’hora d’emissió, la durada, el nombre de notícies, la forma de presentar-les, els recursos utilitzats i en definitiva tot allò relacionat amb l’estructura d’aquests programes. Ens proposem descobrir els canvis que han tingut aquests informatius en català en diferents èpoques. En la mesura que sigui possible, quantificar les variacions que s’hagin produït en diversos aspectes del seu contingut i característiques . En especial els relatius al text llegit i a la imatge. Aquest treball pretén ser una primera aproximació a l’estudi de les estructures dels programes informatius diaris, que certifiqui l’existència d’una línia d’investigació que es pugui seguir en el futur.

Kann man auf die ostseefinnisch-permische Gleichsetzung fi. joukko wotj. l'uk, juk syrj. juk verzichten?

Abstract

State of Iowa Transportation Map, 1983

This document is the State Map of Iowa, both front and back of the year in the title. All maps were are in pdf format and can be used as a historical reference.