Violência contra a mulher: uma temática privilegiada para se trabalhar no ensino superior, mediante artigos de jornal

Este texto tem como objetivo central evidenciar aspectos da temática violência contra a mulher como o assunto privilegiado para se trabalhar no Ensino Superior, particularmente no Curso de Direito, mediante artigos de jornal. Tal formulação é decorrente da reflexão sobre a árdua tarefa da mediação do conhecimento que impõe desafios, algumas vezes desanimadores, sobretudo quando o peso da tradição dá o tom, ou quando os responsáveis pelo ensino encontram-se refratários às mudanças didáticas no seio de alguns cursos superiores. Como postura de uma nova didática, a proposta de se trabalhar com artigos de jornal, sobretudo quando trabalhada com temáticas como a privilegiada neste artigo, revela as possibilidades de aproximação dos resultados das reflexões sobre questões do cotidiano com aspectos da dogmática, muito valorizada, sobretudo, nos Cursos de Direito.

Investigação da colaboração científica na temática de indexação em periódicos on-line em âmbito nacional

This research seeks to demonstrate the scientific collaboration in the field of Information Science, specifically in the thematic indexing, by analyzing the co-authors network, based on scientific collaboration in Brazilian journals online, according to CAPES. We selected six Brazilian journals online, namely: Ciência da Informação; Transinformação; Perspectivas da Ciência da Informação; Encontros BIBLI: Revista Eletrônica de Biblioteconomia e Ciência da Informação; DataGramaZero and Em Questão, totaling 25 articles. It was built in coauthorship network, using Pajek software in order to evaluate interactions between researchers and cohesion of the network by calculating its density.

Colaboração científica na temática redes sociais: análise bibliométrica do ENANCIB no período 2009 - 2010

The aim of this research is to point out the most productive researchers and institutions in the “Social Network” theme, in the ENANCIBs, from 2009 to 2010, as well as to describe their institutional scientific collaboration network. As research procedure, we searched for works with the entry network in the annuals of the event. 169 works were found, from which 120 were developed in co-authorship by 40 institutions. A matrix with the institutional coauthorships was created and the scientific collaboration network was reached. The results point out the same number of both most productive institutions and most productive authors. As for the scientific collaboration network, it is relevant that 37 institutions are interconnected by co-authorship. It’s also relevant that the studies in social network have been more and more present in the Information Science, mainly as investigative method for the construction of knowledge.

A construção dos saberes docentes: um olhar sobre as experiências de professores da disciplina de História acerca da temática de diversidade sexual

Pós-graduação em Educação Escolar - FCLAR

Concepções de professores sobre a temática das chamadas dificuldades de aprendizagem

This study aimed to identify the conceptions of learning difficulties of teachers working in the beginning years of elementary education. In order to analyze such conceptions from the perspective of inclusive education, the study was carried out in two schools in a city of the State of Paraná. Sixteen teachers (mean age of 41 years) participated in the study. Of these, only one had no higher education. Interviews were carried out individually in the teachers` schools. The interviews were conducted with the support of a topic outline including: aspects of classroom management of the classes in which teachers worked; how to identify students with learning disabilities; causes of learning difficulties; how the school can help a student with learning difficulties. Each interview lasted 50 minutes on average. They were transcribed in full and submitted to thematic analysis. Four categories of analysis were determined: characterization of educational institutions' proposal; conceptions on the identification of students with learning difficulties; conceptions about causes of learning difficulties; possibilities for assisting students with learning difficulties. The results indicated that the main factors reported by the participants on the characterization of pupils with learning difficulties were of the cognitive order. The data also showed that the teachers based their opinions on family aspects in order to focus on causes of learning difficulties; they attributed the largest parcel of responsibility for solving such situations to students' families. One of the main conclusions of this study allowed us to consider that the schools that were investigated reported a practice that doesn't meet the inclusive education assumptions, denoted by the attempt to homogenize regular classes.

Estudo do potencial antimutagênico de flavonoides pelo ensaio bacteriano de mutação reversa (teste de ames)

Flavonoides são constituintes fenólicos de plantas que possuem diversas atividades terapêuticas, dentre elas, a atividade antimutagênica. Eles são caracterizados por um esqueleto carbônico C6-C3-C6, em que os componentes C6 são anéis aromáticos e o C3 um anel heterocíclico. Diferenças nessa estrutura podem alterar a atividade e o seu potencial antimutagênico. Para melhor compreensão da atividade antimutagênica exercida pelos flavonoides, neste estudo, os compostos quercetina, kaempferol, luteolina, fisetina, galangina, crisina, flavona, 3-hidroxiflavona, 5-hidroxiflavona e 7-hidroxiflavona, flavonoides que apresentam diferenças no padrão de hidroxilação, foram analisados pelo teste de Ames. Para realização dos ensaios foram utilizadas as cepas TA98, TA100 e TA102 de Salmonella typhimurium em testes com e sem ativação metabólica. Os mutágenos utilizados para comparação do efeito protetor dos flavonoides foram 4-nitro-o-fenilenodiamina (NPD), azida sódica (AZS), mitomicina C (MMC), benzo[a]pireno (B[a]P), aflatoxina B1 (AFB1) e 2-aminoantraceno (2-AA). No ensaio contra o NPD sem ativação metabólica, todos os flavonoides apresentaram efeito antimutagênico, com exceção da fisetina. No ensaio com ativação metabólica contra o B[a]P, todos os flavonoides demonstraram forte efeito antimutagênico, com exceção da quercetina que potencializou o efeito mutagênico do mutágeno. No ensaio contra a AZS sem ativação metabólica, os flavonoides luteolina, crisina, 3-hidroxiflavona e 7-hidroxiflavona reduziram a resposta mutagênica do mutágeno. No ensaio contra a AFB1 com ativação metabólica, os flavonoides kaempferol, luteolina, crisina e galangina (em concentrações mais elevadas) exibiram efeito antimutagênico ...

Estudo de um método para simulação e teste de sistema de freio

The brake system of a Formula SAE car has determinant character in the quality of the project. Any flaw in the design of the brakes, the vehicle is rejected for the competition. The project well done, and its smooth operation, depends on some variables that should be studied and linked to the brake components, as needed by the vehicle. After the calculations, the components were defined according to commercial availability. So it is interesting simulation of braking when the vehicle will be submitted before the implementation of the brake system, saving time and cost. This project also enable the comparison between components from different brands. This work shows the study of a method that would allow simulate and test the brake system in an upcoming project for a bench test

Valor de corte para teste respiratório com isótopos estáveis (Carbono 13) no diagnóstico do Helicobacter pylori utilizando IRMS para análise do sopro

After the isolation of Helicobacter pylori from an injury at the stomach mucosa by Marshall and Wareen, work that was recognized with the Nobel Prize of Medicine or Physiology in 2005, many other works showed the relationship between the presence of H. pylori and diseases at the digestive system, such as gastritis, gastric, duodenal and peptic ulcer, and stomach cancer. The 13C-Urea Breath Test - 13C-UBT is a non-invasive diagnostic method that utilizes the breath of a patient to determine the presence of H. pylori through stable isotopes. This work aimed to find an ideal 13C-UBT Isotopic Ratio Mass Spectroscopy cut-off value (a threshold between positive and negative) to diagnose H. pylori infection at Brazilian population. Patients were selected at the UNESP-Botucatu Clinical Hospital Endoscopy Section. With these results it was possible to indicate that the best cut-off value is between 2.5 to 6 ‰ of Delta Over Baseline (DOB)

Desenvolvimento e validação de uma técnica quantitativa de análise de imagem para avaliação do teste do cometa corado pela prata

The comet assay is a method of DNA damage analysis widely used to quantify oxidative damage, crosslinks of DNA, apoptosis and genotoxicity of chemicals substances as chemical, pharmaceuticals, agrochemicals products, among others. This technique is suitable to detect DNA strand breaks, alkali-labile sites and incomplete excision repair sites and is based on the migration of DNA fragments by microeletroforesis, DNA migrates for the anode forming a “tail”, and the formed image has the appearance of a comet. The slides can be stained with fluorescence or silver, having differences in the microscopy type used for the analysis and the possibility of storage of the slides, moreover, the first one is a stained-method with more difficulties of accomplishment. The image analysis can be performed by a visual way, however, there is a disadvantage as the subjectivity on the results, that can be minimized by an automated method of digital analysis. This process was studied in this report with the aim to perceive the validation of the digital analysis turning it a quantitative method with larger reproductibility, minimizing the variability and imprecision due to the subjective analysis. For this validation we selected 50 comets photographed in a standardized way and printed, afterwards, pictures were submitted to three experienced appraisers, who quantified them manually. Later, the images were processed by free software ImageJ 1.38x, printed and quantified manually by the same appraisers. The intraclass correlation was higher to comet measures after image processing. Following, an algorithm of automated digital analysis from the measures of the comet was developed; the values obtained were compared with those 12 estimated manually after the processing resulting high correlation among the measures. The use of image analysis systems increases ...(Complete abstract click electronic access below)

A temática ambiental no Exame Nacional do Ensino Médio (ENEM)

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A temática ambiental nos vestibulares das Universidades Estaduais Paulistas (USP, UNESP e UNICAMP)

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Análise etofarmacológica do teste de exposição ao rato (interação presa-predador) para o estudo da ansiedade em camundongos

Com o objetivo de propor mecanismos que auxiliem na compreensão da neurobiologia do medo e da ansiedade, diversos modelos animais vem sendo utilizados. Dentre eles destaca-se o Teste de Exposição ao Rato (RET), que é um modelo etológico de interação presa (camundongo) – predador (rato), conhecido por eliciar a expressão de diversos tipos de comportamentos defensivos no camundongo, tais como avaliação de risco, esquiva, congelamento, entre outros. Com o intuito de aumentar a aversividade do modelo proposto por Yang e colaboradores (2004), foi proposto um novo modelo de RET, semelhante ao modelo padrão, porém com alterações de algumas variáveis como aumento da luminosidade, ausência de maravalha, alteração do local de inserção do camundongo no aparato, substituição da tela de arame (usada na separação da superfície) por uma tela de acrílico e arame e uma divisão virtual da superfície em duas partes, uma distante da tela por 10 cm (superfície proximal) e outra com 13 cm até chegar ao túnel (superfície distal). Um estudo piloto realizado comparando o novo teste de exposição ao rato com o modelo padrão demonstrou que no novo modelo de exposição há uma maior preferência pela presa às áreas protegidas (toca e túnel) e uma maior expressão de avaliação de risco, indicando talvez uma maior sensibilidade à expressão de comportamentos defensivos de camundongos e possivelmente a fármacos que atuem no sistema de defesa. No presente estudo foram investigados os efeitos dos (i) benzodiazepínicos diazepam e alprazolam, (ii) dos fármacos ansiogênicos cafeína e pentilenotetrazol e (iii) do antidepressivo fluoxetina (aguda e cronicamente). O tratamento com alprazolam resultou num efeito antiaversivo mais evidente quando comparado ao diazepam. O tratamento agudo 10 com cafeína, por sua vez, apresentou um efeito ansiogênico bastante sutil, diferente... (Resumo completo, clicar acesso eletrônico abaixo)

Avaliação da toxicidade da vinhaça utilizando Oreochromis niloticus (Perciformes: Cichlidae) como organismo teste

Contamination of rivers and lakes, waste disposed by infiltration into the soil as fertilizer, for example, has been highlighted around the world, since such compounds can contain toxic elements, causing changes in aquatic and/or terrestrial ecosystem. Due to the possible presence of these elements in these wastes, it is possible assess damage to organisms exposed through breaks in genetic material and mutations. In this sense, this work aimed at exploring the cytotoxic, mutagenic and genotoxic vinasse pontential, residue used as fertilizer, from the processing of sugar cane into alcohol, using fish (Oreochromis niloticus - Cichlidae) as a test organism. The individuals were exposed to different dilutions of vinasse in the water and later carried out analysis of their erythrocytes using the micronucleus test and nuclear abnormalities associated and the comet assay. In the first bioassay, tilapia exhibited 5% and 10% vinasse concentrations died after 48h. The number of micronucleated erythrocytes was statistically significant for the 1% vinasse concentration and also for nuclear abnormalities such as broken-egg and nuclear bud, when compared with negative and positive controls; were also significant lobed type erythrocytes, when compared to the negative control. The test results of the comet assay were not significant for 1% vinasse when compared to the negative control, due to the high rate of comets with damage control, which is unusual. The same was observed for changes as notched and blebbed type. In the second chemical analyzes conducted, the detection of heavy metals in the vinasse sample, charged only the presence of copper and chromium, the latter with a concentration 89 times higher than in the first test. Differentially the first bioassay, fish exposed to dilution of 5% did not die... (Complete abstract click electronic access below)

Avaliação do potencial mutagênico do biodiesel e de misturas de biodiesel/diesel, por meio do teste do micronúcleo em sangue periférico e de histologia de brânquias de Oreochromis niloticus

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Cartografia temática do atlas de sensibilidade ambiental a derramamentos de óleo do litoral paulista

The objective of this paper is the elaboration and implementation of procedures in a cartographic representation related by fundamental of thematic cartography and graphic semiology for the standardization of the Environmental Oil Spill Sensitivity Maps supported by a Geographic Information Systems (GIS) for handling and modeling of a large number of variables. These make up the Environmental Sensitivity Atlas to Oil Spills in Coastal Paulista, and that represents the phenomena that occur in geographic space accurately so as to highlight the importance of each element in the evaluation and protection of areas of greater sensitivity oil. The composition of the cartographic documents considers the Littoral Sensitivity Index (LSI), biological resources and the resources for human use that could be negatively impacted. Thus, the information contained in each map was carefully evaluated before implementation, so that the cartographic representations of various resources, environments, and other ISLs, the reader should issue an immediate message that could be understood clearly, without requiring prior knowledge of specialized. Another aspect was the distribution harmoniously all the elements contained in the document, so that information could be enough without overwhelming it. It was also taken a certain care, so each symbol could be used properly in order that there is no conflict in the information.