Transcatheter Aortic Valve Implantation and Morbidity and Mortality-Related Factors: a 5-Year Experience in Brazil

Abstract Background: Transcatheter aortic valve implantation has become an option for high-surgical-risk patients with aortic valve disease. Objective: To evaluate the in-hospital and one-year follow-up outcomes of transcatheter aortic valve implantation. Methods: Prospective cohort study of transcatheter aortic valve implantation cases from July 2009 to February 2015. Analysis of clinical and procedural variables, correlating them with in-hospital and one-year mortality. Results: A total of 136 patients with a mean age of 83 years (80-87) underwent heart valve implantation; of these, 49% were women, 131 (96.3%) had aortic stenosis, one (0.7%) had aortic regurgitation and four (2.9%) had prosthetic valve dysfunction. NYHA functional class was III or IV in 129 cases (94.8%). The baseline orifice area was 0.67 ± 0.17 cm2 and the mean left ventricular-aortic pressure gradient was 47.3±18.2 mmHg, with an STS score of 9.3% (4.8%-22.3%). The prostheses implanted were self-expanding in 97% of cases. Perioperative mortality was 1.5%; 30-day mortality, 5.9%; in-hospital mortality, 8.1%; and one-year mortality, 15.5%. Blood transfusion (relative risk of 54; p = 0.0003) and pulmonary arterial hypertension (relative risk of 5.3; p = 0.036) were predictive of in-hospital mortality. Peak C-reactive protein (relative risk of 1.8; p = 0.013) and blood transfusion (relative risk of 8.3; p = 0.0009) were predictive of 1-year mortality. At 30 days, 97% of patients were in NYHA functional class I/II; at one year, this figure reached 96%. Conclusion: Transcatheter aortic valve implantation was performed with a high success rate and low mortality. Blood transfusion was associated with higher in-hospital and one-year mortality. Peak C-reactive protein was associated with one-year mortality.

Framework of quality measurement in CASE tool based software development

Magdeburg, Univ., Fak. für Informatik, Diss., 2010

Molecular mechanisms of classical fear conditioning : GABAergic factors and their role in fear-related network activities

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2010

Reusability evaluation of component-based embedded automative software systems

Magdeburg, Univ., Fak. für Informatik, Diss., 2012

Analysis and removal of code clones in software product lines

Magdeburg, Univ., Fak. für Informatik, Diss., 2013

Hypermodelling : next level software engineering with data warehouses

Magdeburg, Univ., Fak. für Informatik, Diss., 2013

Syagrus oleracea (Mart.) Becc. and closely related taxa / S. F. Glassman. --

v.32:no.3(1968)

Software for Explicitly Parallel Memory-Centric Processor Architecture

Advances in computer memory technology justify research towards new and different views on computer organization. This paper proposes a novel memory-centric computing architecture with the goal to merge memory and processing elements in order to provide better conditions for parallelization and performance. The paper introduces the architectural concepts and afterwards shows the design and implementation of a corresponding assembler and simulator.

Software phantoms in medical image analysis

Magdeburg, Univ., Fak. für Informatik, Diss., 2015

Reward- and attention-related determinants of color selection in human visual cortex

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2015

Entwicklung einer benutzerfreundlichen Software zur Berechnung von Rundfunk-Sendeantennen

Die Abteilung Sendertechnik des Norddeutschen Rundfunks betreibt die Sender zur Versorgung der Rundfunknutzer und befasst sich unter anderem mit der Planung und Optimierung von Sendeantennen. Das Ziel dieser Bachelorarbeit war die Entwicklung einer Software, mit der Horizontaldiagramme von Antennen erstellt, angepasst und dokumentiert werden können. Dafür wurde eine vorhandene LabVIEW-Software in ihren Grundzügen übernommen, in eine neue, in Java entwickelte Programmumgebung übertragen und dort erweitert und optimiert. Die Arbeit dokumentiert die Grundlagen der Sendeantennenplanung und die programmiertechnischen Entwicklungsschritte bis hin zur fertiggestellten und funktionsfähigen Software. Im Speziellen geht sie dabei auf die Berechnung von Antennensystemen, die Erstellung von Horizontaldiagrammen sowie die objektorientierte Programmierung und die Erstellung von grafischen Benutzeroberflächen ein. Dabei werden die einzelnen Entwicklungsschritte dokumentiert und erläutert sowie die Validierung der Software beschrieben.

A note on the Philippine frogs related to Rana macrodon.

v.39:no.23(1958)

Anchovia landivarensis, a new species of Anchovy (Pisces: Engraulidae) from Belize, Central America : with comments on related species / David W. Greenfield and Terry Greenfield.

v.65:no.9(1975) [Incomplete]

Macroecologia de carnívoros do Novo Mundo (Mammalia): envelopes de restrição e análise de padrões filogenéticos

The relationship between body size and geographic range was analyzed for 70 species of terrestrial Carnivora ("fissipeds") of the New World, after the control of phylogenetic patterns in the data using phylogenetic eigenvector regression. The analysis from EcoSim software showed that the variables are related as a triangular envelope. Phylogenetic patterns in data were detected by means of phylogenetic correlograms, and 200 simulations of the phenotypic evolution were also performed over the phylogeny. For body size, the simulations suggested a non-linear relationship for the evolution of this character along the phylogeny. For geographic range size, the correlogram showed no phylogenetic patterns. A phylogenetic eigenvector regression was performed on original data and on data simulated under Ornstein-Uhlenbeck process. Since both characters did not evolve under a simple Brownian motion process, the Type I errors should be around 10%, compatible with other methods to analyze correlated evolution. The significant correlation of the original data (r = 0.38; P < 0.05), as well as the triangular envelope, then indicate ecological and adaptive processes connecting the two variables, such as those proposed in minimum viable population models.

Associative learning in wild Anastrepha obliqua females (Diptera, Tephritidae) related to a protein source

The aim of the present study was to determine whether wild adult Anastrepha obliqua (Macquart, 1835) females are able to associate a compound (quinine sulphate - QS) not related to their habitual diet with a protein-enriched food. Females were first fed on diets based on brewer yeast and sucrose containing or not QS. The groups were then allowed to choose between their original diets and a diet with or without QS, depending on the previous treatment, and between a diet based on agar and a diet containing agar and QS. When the nutritional value of the diets was adequate, the females did not show any preference for the diet with or without QS. With respect to the agar diet and the agar + QS diet, females previously fed on a nutritive diet containing QS preferred the diet containing QS, indicating an association between the compound and the nutritional value of the diet. The importance of this behavioral strategy is discussed.