Sonic hedgehog signaling regulates mode of cell division of early cerebral cortex progenitors and increases

The morphogen Sonic Hedgehog (SHH) plays a critical role in the development of different tissues. In the central nervous system, SHH is well known to contribute to the patterning of the spinal cord and separation of the brain hemispheres. In addition, it has recently been shown that SHH signaling also contributes to the patterning of the telencephalon and establishment of adult neurogenic niches. In this work, we investigated whether SHH signaling influences the behavior of neural progenitors isolated from the dorsal telencephalon, which generate excitatory neurons and macroglial cells in vitro. We observed that SHH increases proliferation of cortical progenitors and generation of astrocytes, whereas blocking SHH signaling with cyclopamine has opposite effects. In both cases, generation of neurons did not seem to be affected. However, cell survival was broadly affected by blockade of SHH signaling. SHH effects were related to three different cell phenomena: mode of cell division, cell cycle length and cell growth. Together, our data in vitro demonstrate that SHH signaling controls cell behaviors that are important for proliferation of cerebral cortex progenitors, as well as differentiation and survival of neurons and astroglial cells.

Occupational compensation survey--pay only. Connecticut / U.S. Department of Labor, Bureau of Labor Statistics.

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Terceirização de serviços dos trabalhadores de escolas públicas do Distrito Federal : processos de intensificação e precarização do trabalho

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Educação, Programa de Pós-Graduação em Educação, 2016.

The negotiability of labor rights: an economic analysis

This paper shows the results of the applied research titled "Negotiating labor rights: an economic analysis", which analyzes the legal regulation on individual labor rights negotiation in Colombia from the viewpoint of basic economic principles (Economic Analysis of Law), in order to identify the inefficiencies caused by the prohibition of this type of negotiations -- After introducing the discipline of the Economic Analysis of Law, this article specifically analyzes the main legal principles that support the prohibition of individual negotiations which summed to the economic characteristics of the agents (workers), produce inefficiency in the labor markets

Population structure and sexual maturity of the calico box crab Hepatus epheliticus Linnaeus (Brachyura, Hepatidae) from Yucatan Peninsula, Mexico

The calico box crab Hepatus epheliticus is an abundant species from shallow and continental shelf waters of the Atlantic coast of USA and Mexico. Information about population structure and sexual maturity is absent, even though this crab is caught to be used as bait for the octopus fishery in the Campeche Bank, Mexico. In order to achieve such information, a total of 768 individuals were collected from January to March 2010 through baited traps installed in the Yucatan Peninsula, Mexico. Our results showed that sex ratio is biased towards more males than females (1:0.55), contradicting to that reported in other brachyuran crabs. The absence of ovigerous females suggests that they did not enter into the traps during embryogenesis. Males reached a larger maximum size than females (64.0 +/- 6.15 and 58.4 +/- 5.60 mm carapace width, respectively). The general scheme of growth being positive allometric throughout ontogeny of both sexes. Males presented a transition phase from juveniles to adult corresponding to the puberty moult. The estimation of the onset of functional sexual maturity revealed a steady situation for the population, with 21.5 and 13.8% of males and females, respectively, morphologically immature at the time of catch. This study constitutes the first report on population structure and sexual maturity in a population of the calico box crab H. epheliticus.

Construindo novos túneis : subterfúgios das engenheiras para deslocar as fronteiras da divisão sexual da ciência e da tecnologia

O domínio do conhecimento científico é historicamente masculino. Mesmo com a crescente inserção das mulheres nesse campo, pode-se dizer que a lógica de fazer ciência ainda está pautada em valores masculinizados. Nosso trabalho pretende mapear a percepção das engenheiras sobre suas escolhas pelas ciências exatas e por um campo profissional tradicionalmente masculino, a engenharia. A nossa hipótese de trabalho inicial afirmava que as escolhas das engenheiras durante sua trajetória acadêmica e profissional são dificultadas pela forte tendência à perpetuação da divisão sexual da educação superior, da ciência e do trabalho. O objetivo principal da pesquisa foi desvendar os argumentos que levam à naturalização da separação entre cursos de homens e cursos de mulheres, áreas de trabalho femininas e masculinas ainda que dentro da mesma área do saber ou do campo profissional. Para tanto, foi realizado estudo qualitativo com entrevistas semiestruturadas à sete engenheiras de diferentes áreas de uma empresa estatal, sociedade anônima de economia mista, com sede no Distrito Federal, atuante no serviço público de energia elétrica. Observou-se a perpetuação da divisão sexual horizontal e vertical da ciência, tecnologia e do trabalho, que se reinventa nas trajetórias traçadas pelas engenheiras, formando guetos “permitidos” às mulheres, ainda que dentro da própria engenharia. _________________________________________________________________________________________________ ABSTRACT

HOG CHAINS AND MARK TWAINS: A STUDY OF LABOR HISTORY, ARCHAEOLOGY, AND INDUSTRIAL ETHNOGRAPHY OF THE STEAMBOAT ERA OF THE MONONGAHELA VALLEY 1811-1950

This dissertation examines a unique working class in the United States, the men and women who worked on the steamboats from the Industrial Revolution until the demise of steam-powered boats in the mid-20th century. The steamboat was the beginning of a technological system that was developed in America and used in such great numbers that it made the rapid population of the Trans-Appalachian West possible. The steamboat was forever romanticized by images of the antebellum South or the quick wit of Samuel Clemens and his sentimental book, Life on the Mississippi. The imagination swirls with thoughts of boats, bleach white, slowly churning the calm waters of some Spanish moss covered river. The reality of the boats and the experience of those who worked on them has been lost in this nostalgic vision. This research details the history of the western steamboat in the Monongahela Valley, the birthplace of the commercial steamboat industry. The first part of this dissertation examines the literature of authors in the field of labor history and Industrial Archaeology to place this work into the larger context of published literature. The second builds a framework for understanding the various eras that the steamboat went through both in terms of technological change, but also the change the workers experienced as their identity as a working class was being shaped. The third part details the excavations of two steamboat captains houses, those of Captain James Gormley and Captain Michael A. Cox. Both men represented a time in which the steamboat was in an era of transition. Excavations at their homes yield clues to their class status and how integrated they were in the local community. The fourth part of this study documents the oral histories of steamboat workers, both men and women, and their experience on the boats and on the river. Their rapidly declining population of those who lived and worked on the boats gives urgency for their lives to be documented. Finally, this study concludes with a synthesis of how worker identity solidified in the face of technological, socio-economic, and ideological change especially during their push for unionization and the introduction of the diesel towboat.

Measuring the effectiveness of two public policies on the sectors of labor markets and urban infraestructure. Experimental and quasi-experimental evidence from developing countries

La tesis presenta evidencia rigurosa de la efectividad de las políticas públicas utilizando metodologías experimentales y cuasi-experimentales. La tesis comienza con una introducción completa y una revisión rigurosa de las metodologías que se utilizarán en el análisis posterior de los datos. El primer capítulo, "Habilidades personales y habilidades técnicas en programas de formación de jóvenes. Evidencia Experimental de Largo Plazo de República Dominicana ", evalúa el impacto de un programa de empleo de los jóvenes en una serie de variables de interés. El programa ofrece capacitación en las habilidades vocacionales y en las habilidades no cognitivas a jóvenes en riesgo de exclusión social. Cabe destacar que la metodología utilizada para evaluar el programa es un ensayo controlado aleatorio, que proporciona evidencia robusta del efecto causal del programa. Mientras que estudios previos analizaron el impacto de los programas para jóvenes relacionados, ningún estudio anterior había evaluado los efectos de 4 años después de la implementación del programa. Esto representa una contribución importante debido a que las ganancias a corto plazo de varios programas de desarrollo han demostrado no ser sostenida en el tiempo. Esto es también lo que este estudio encuentra para los resultados del mercado de trabajo: mientras que el programa genera una mejora a corto plazo de los resultados de empleo para las mujeres, este efecto se disipa en el largo plazo. Sin embargo, el programa parece conducir a cambios persistentes en las expectativas del mercado de trabajo de las mujeres: las mujeres que asistieron al entrenamiento de informar una visión más optimista de las perspectivas del mercado de trabajo hasta 4 años después del programa...

STATE OF SOUTH CAROLINA OFFICE OF THE GOVERNOR DIVISION OF FOSTER CARE REVIEW ANNUAL REPORT - 1994-95

The South Carolina Foster Care Review Board at the Office of Executive Policy and Programs annually publishes a report with summary of programs, recommendations, demographic and statistical information, and directory of state board and staff.

OFFICE OF THE GOVERNOR DIVISION OF FOSTER CARE REVIEW 1996-1997 ANNUAL REPORT

The South Carolina Foster Care Review Board at the Office of Executive Policy and Programs annually publishes a report with summary of programs, recommendations, demographic and statistical information, and directory of state board and staff.

OFFICE OF THE GOVERNOR DIVISION OF FOSTER CARE REVIEW 1998-1999 ANNUAL REPORT

The South Carolina Foster Care Review Board at the Office of Executive Policy and Programs annually publishes a report with summary of programs, recommendations, demographic and statistical information, and directory of state board and staff.

Into the Spotlight: Bringing Transparency, Consistency, and Efficiency to the Division of Appeals and Hearings

Currently, the Division of Appeals and Hearings of the South Carolina Department of Health and Human Services has no specific presence on the agency's website to provide information or to allow for the electronic submission of appeals. This project's focus was developing an online presence for the Division on SCDHHS' website. The page will make the Division's procedures publicly available to beneficiaries, providers, and agency program staff who attend hearings. Additionally, parties will have a secure online portal through which they can file appeals and upload supporting documentation, reducing the need to send appeals via first class mail. The online appeal portal will further the agency' s goal of reducing paper.

2016 SOUTH CAROLINA DEPARTMENT OF LABOR, LICENSING AND REGULATION ANNUAL REPORT

Each year the South Carolina Department of Labor, Licensing and Regulation publishes a report with summary of agency-related legislation passed, descriptions of each office, and yearly statistics.