The surprising evolutionary history of South American deer

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Subtle Cognitive Deficits in Adults With a Previous History of Sydenham's Chorea During Childhood

Objective. To evaluate the neuropsychological profile and health-related quality of life (HRQOL) of adults who had rheumatic fever (RF) during childhood with and without Sydenham's chorea (SC).Methods. Three groups of patients were assessed: adults who had RF with SC during childhood (SC group), adults who had RF without SC during childhood (RF group), and controls (CT group). A range of neuropsychological tests looked at several cognitive domains. HRQOL was measured through a Brazilian version of the Short Form 36 (SF-36) health survey.Results. Twenty patients were included in the SC group, 23 patients in the RF group, and 19 patients in the CT group. The 3 groups were homogeneous regarding sex (P = 0.078), age (P = 0.799), schooling (P = 0.600), socioeconomic status (P = 0.138), intelligence quotient (P = 0.329), and scores for anxiety (P = 0.156) and depression (P = 0.076). The SC group demonstrated inferior performance in tests that assessed attention (Digit Span Forward [ P = 0.005], Corsi Block Forward [ P = 0.014]), speeded information processing (Trail Making A [ P = 0.009], Symbol Search [ P = 0.042]), and executive functions and working memory (Corsi Block Backward [ P = 0.028]), and higher scores for attention deficit scale (P = 0.030) when compared with the RF and CT groups. They also showed a tendency toward lower scores in the physical aspects, vitality, emotional aspects, and mental health domains of the SF-36. The RF group had a lower score for the general health domain than the CT group (P = 0.030).Conclusion. Patients who had SC during childhood can exhibit inferior performance in tasks that evaluate attention, speeded information processing, executive functions, and working memory in adult life. Therefore, there is indirect evidence of the persistence of dysfunction in cerebral circuits involved with the basal ganglia. They also presented a worse self-evaluation in HRQOL that was not related to cognitive impairments.

Effect of cocaine on periadolescent rats with or without early maternal separation

Cocaine-induced behavioral sensitization and weight loss were investigated in periadolescent Wistar rats kept with their mothers or subjected to repeated maternal separation. Litters allocated to the separation procedure were placed in a temperature-controlled (33ºC) chamber for 3 h per day from postnatal day 6 (P6) to P20. Non-handled rats were left undisturbed until weaning. Treatments were started on P30-31 and the test was performed on P36-37. Animals received injections of saline or cocaine (10 mg/kg, sc) twice daily for 5 days. on day 6 all animals received saline. on day 7 animals were challenged with 10 mg/kg cocaine and their locomotion was evaluated in activity cages. A third group received saline throughout the 7-day period. Body weights were recorded on P30-31 and P36-37. Two-way ANOVA on body weights showed a main effect of treatment group (F(1,35) = 10.446, P = 0.003; N = 10-12). Non-handled rats treated with cocaine for 5 days gained significantly less weight, while no significant effect was observed in maternally separated rats. Two-way ANOVA revealed a main effect of drug treatment on locomotor activity (F(2,32) = 15.209, P<0.001; N = 6-8), but not on rearing condition (F(1,32)<0.001, P = 0.998). Animals pretreated with cocaine showed a clear behavioral sensitization relative to the saline group. No difference in the magnitude of sensitization was found between separated and non-handled animals. Only the effect of cocaine on weight gain was significantly affected by repeated episodes of early maternal separation during the pre-weaning period.

The Development of Science Education Research in Brazil and Contributions from the History and Philosophy of Science

Over the last 50 years a new research area, science education research, has arisen and undergone singular development worldwide. In the specific case of Brazil, research in science education first appeared systematically 40 years ago, as a consequence of an overall renovation in the field of science education. This evolution was also related to the political events taking place in the country. We will use the theoretical work of Rene Kaes on the development of groups and institutions as a basis for our discussion of the most important aspects that have helped the area of science education research develop into an institution and kept it operating as such. The growth of this area of research can be divided into three phases: The first was related to its beginning and early configurations; the second consisted of a process of consolidation of this institution; and the third consists of more recent developments, characterised by a multiplicity of research lines and corresponding challenges to be faced. In particular, we will analyse the special contributions to this study gleaned from the field known as the history and philosophy of science.

Diagênese e proveniência dos arenitos da tectonossequência Rifte na bacias do Rio do Peixe Araripe, NE do Brasil

This thesis presents diagenetic and provenance studies of sandstones belonging to the Rift Tectonosequence of the Rio do Peixe and Araripe basins. These basins are located in the interior of Northeast Brazil aligned along the Trend-Cariri Potiguar. Their origin is related to the Early Cretaceous rifting event. In terms of lithostratigraphy, the studied section corresponds to the Antenor Navarro, Sousa and Rio Piranhas formations of the Rio do Peixe Basin, and the Missão Velha and Abaiara formations of the Araripe Basin, outcropping in the central-west Cariri Valley. A facies analysis was performed and identified nine distinct sedimentary facies for the Rio de Peixe Basin and ten sedimentary facies for the Araripe Basin, individualized according to the different rock types and their sedimentary structures. These facies associations to led paleoenvironments interpretations and their vertical succession allowed understanding the evolution of the depositional setting during the cronostratigraphic interval studied in these basins. Based on petrographic and diagenetic studies it was possible to characterize the texture and mineralogy of these sandstones, identifying their diagenetic stage and the grain framework provenance. The petrographic study allowed to classify the lithotypes studied in both basins as quartzarenites. Such quartzarenites, in general, are rich in quartz, feldspar and lithic fragment grains, and at accessory levels tourmaline, sphene, zircon, epidote and other mineralogy. The diagenetic history of the studied rocks proved to be very complex, being characterized by a variety mineral of phases that succeeded each other during the eo, meso and telodiagenetic stages. According to the studied formation and the textural and compositional aspects of the rocks, some processes were more or less active, while others were even absent. The eodiagenetic stage is marked by mechanical infiltration of clays and early mechanical compactional processes. The mesodiagenetic phase is characterized by continuity of the mechanical compaction and the beggining of chemical compaction, with quartz and feldspar overgrowths, precipitation of kaolinite, alteration of framework grains to chlorite and illite, and finally, precipitation of opaque minerals. The telodiagenetic stage is represented by the oxidation of some grains, matrix and cements. For the provenance analysis of the studied sandstones were used ternary diagrams whose vertices correspond to the percentage of quartz, feldspar and lithic fragments. This study allowed identifies the source area of these rocks as continental blocks. It was also possible, based on the chemical stability and mineralogical maturity of the rocks, recognize that the Antenor Navarro Formation of the Rio do Peixe Basin, and the upper section of the Missão Velha Formation of Araripe Basin have less maturity and stability when compared with the other studied formations

CMS tracking performance results from early LHC operation

The first LHC pp collisions at centre-of-mass energies of 0.9 and 2.36 TeV were recorded by the CMS detector in December 2009. The trajectories of charged particles produced in the collisions were reconstructed using the all-silicon Tracker and their momenta were measured in the 3.8 T axial magnetic field. Results from the Tracker commissioning are presented including studies of timing, efficiency, signal-to-noise, resolution, and ionization energy. Reconstructed tracks are used to benchmark the performance in terms of track and vertex resolutions, reconstruction of decays, estimation of ionization energy loss, as well as identification of photon conversions, nuclear interactions, and heavy-flavour decays.

Terrane transfer during the Grenville orogeny: tracing the Amazonian ancestry of southern Appalachian basement through Pb and Nd isotopes

Whole rock Pb isotope data can be used to determine the provenance of different blocks within the Rodinia supercontinent, providing a test for paleogeographic reconstructions. Calculated isotopic values for the source region of the Grenville-deformed SW Amazon craton (Rondonia, Brazil), anchored by published U-Pb zircon ages, are compared to those from the Grenville belt of North America and Grenvillian basement inliers in the southern Appalachians. Both the SW Amazon craton and the allochthonous Blue Ridge/Mars Hill terrane are defined by a similar Pb isotopic signature, indicating derivation from an ancient source region with an elevated U/Pb ratio. In contrast, the Grenville Province of Laurentia (extending from Labrador to the Llano Uplift of Texas) is characterized by a source region with a distinctly lower, time-integrated U/Pb ratio. Published U-Pb zircon ages (ca. 1.8 Ga) and Nd model ages (1.4-2.2 Ga) for the Blue Ridge/Mars Hill terrane also suggest an ancient provenance very different from the rest of the adjacent Grenville belt, which is dominated by juvenile 1.3-1.5 Ga rocks. The presence of mature continental material in rocks older than 1.15 Ga in the Blue Ridge/ Mars Hill terrane is consistent with characteristics of basement rocks from the SW Amazon craton. High-grade metamorphism of the Blue Ridge/Mars Hill basement resulted in purging of U, consistent with observations of the rest of the North American Grenville province. In contrast, the Grenvillian metamorphic history of the Amazon appears to have been much more heterogeneous, with both U enrichment and U depletion recorded locally. We propose that the Blue Ridge/ Mars Hill portion of the Appalachian basement is of Amazonian provenance and was transferred to Laurentia during Grenvillian orogenesis after similar to1.15 Ga. The presence of these Amazonian rocks in southeastern Laurentia records the northward passage of the Amazon craton along the Laurentian margin, following the original collision with southernmost Laurentia at ca. 1.2 Ga. (C) 2004 Elsevier B.V. All rights reserved.

Natural History of the Lutz's Frog Cycloramphus lutzorum Heyer, 1983 (Anura: Cycloramphidae) in the Brazilian Atlantic Forest: Description of the Advertisement Call, Tadpole, and Karyotype

We describe the advertisement call, tadpole, karyotype, and additional information on the natural history of Cycloramphus lutzorum from southern Brazil. Sonograms were generated from digitally recorded calls. Tadpoles were collected in the field for description in the lab, and an adult was collected for karyotyping. Data on seasonal activity were gathered monthly from November 2005 to November 2007. All tadpoles (N = 21), juveniles (N = 18), and adults (N = 52) were found exclusively in streams. Reproduction, as identified by calling frogs, occurred from July through November. Frogs call all day long, but mostly at dusk, from rock crevices inside the stream edges near the splash zone. The call is short and loud, with 11 pulsed notes, of 491-641 ms, with a dominant frequency of 0.98-1.39 kHz. We describe the exotrophic and semiterrestrial tadpoles, always found in constantly humid vertical rock walls in the stream. Tadpoles of C. lutzorum are recognized by differences in labial tooth row formula, eye diameter, body shape, position of nares, and development of tail. Like congeneric species, the karyotype of C. lutzorum comprises 26 metacentric and submetacentric chromosomes. Cycloramphus lutzorum is restricted to and adapted for living in fast flowing streams, many of which are threatened by deforestation, pollution, and habitat loss. Therefore, we recommend the status of C. lutzorum be changed from its current "Data Deficient" to "Near Threatened (NT)" in the IUCN species red list.

Denudation history of the Bocaina Plateau, Serra do Mar, southeastern Brazil: Relationships to Gondwana breakup and passive margin development

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Burial history and porosity evolution of Brazilian upper Jurassic to tertiary sandstone reservoirs

The parameter time-depth index (TDI) is applied in this study to quantify empirically the influence of burial history on sandstone porosity evolution. The TDI, expressed in kilometers per million years of age, is defined as the area in the burial history diagram enclosed by the burial curve of the reservoir and the axes of the diagram. In practice, reservoir depths during burial history are integrated at regular time intervals of 1 m.y. The calculations exclude present-day bathymetry or paleobathymetry. Sandstone reservoirs from several sedimentary basins along the Brazilian continental margin (Santos, Campos, Espírito Santo, Cumuruxatiba, Recôncavo, Sergipe, Alagoas, and Potiguar) were analyzed to investigate the evolution of porosity against TDI. These Upper Jurassic to Tertiary sandstones lie in depths of 700 to 4900 m, and are hydrocarbon charged (oil or gas). Average porosities of most of these reservoirs were obtained from core analysis, and a few porosity data were taken from well log interpretations. Detrital constituents of the sandstones are mainly quartz, feldspar, and granitic/gneissic rock fragments. Sandstones were grouped into three main reservoir types, based on composition (detrital quartz content) and grain sorting: Type I (average quartz content <50%) are very coarse grained to conglomeratic, poorly to very poorly sorted lithic arkoses. Rock fragments are mainly granitic/gneissic and coarse grained. Type II (average quartz content ranging from 50% to 70%) are fine- to coarse-grained (pebbles absent or occurring in small percentages), moderately sorted arkoses. Type III (average quartz content >80%) are fine to coarse, moderately to poorly sorted quartz arenites or subarkoses. Plots of average porosity against depth show great dispersion in porosity values; such dispersion is mostly due to differences in the reservoir burial histories. However, plotting porosity values against the TDI for individual reservoir types produces well-defined trends. The decrease in porosity is less marked in Type III reservoirs, intermediate in Type II, and faster in Type I. Such plots suggest that it is possible to make relatively accurate porosity predictions based on reservoir TDI, texture, and composition,: within the constraints of reservoir depth/age and basin tectonics analyzed in this study.

Puncture wounds by driftwood catfish during bucket baths: Local habits of riverside people and fish natural history in the Amazon

Objective. - To assess the prevalence of stings by small spiny driftwood catfish (carataí) of the genus Centromochlus (Auchenipteridae) accidentally caught in buckets during bucket bathing by riverside people along the Brazilian Amazon and to determine the probability of catching specimens of these fish during random throws of a bucket into the river. Methods. - We interviewed 27 adult residents living at the confluence of the Negro and Solimões rivers in Brazil regarding whether or not they had ever been stung by driftwood catfish while bucket bathing. To assess the likelihood of catching catfish in bathing buckets, we randomly threw a typical plastic bucket used for bathing in 4 series of 10 throws into the river at dusk or night around a floating house. Results. - Seventeen of the 27 subjects (63%) reported being injured by driftwood catfish during bucket bathing. Three individuals (17.6%) had been injured 2 to 3 times, totaling 23 puncture accidents. All stings occurred at dusk or early night. In the 4 series of 10 bucket throws, we caught 3 driftwood catfish (in 1 series we did not catch any fish). Thus, the chance of catching a driftwood catfish in a single bucket throw at dusk was slightly less than 10%. Conclusions. - The prevalence of stings by driftwood catfish to people bucket bathing in this section of the Brazilian Amazon is high, partly because of the relatively high chances of catching these small catfish during random throws of a bathing bucket into the river.

A tectônica meso-cenozóica de parte da borda nordeste da Bacia do Paraná: traços de fissão em apatita

The possible development of thermal events in the central portion of São Paulo state was described based on apatite fission track analysis. Using apatites of sedimentary rocks of the Paraná Basin, modeling the thermal history was made possible due to the homogeneity of the data. Every thermal history begins with a total annealing of fission tracks, related to the Serra Geral magmatism, evolving into a cooling period. In addition to cooling after the magmatism (Early Cretaceous) two other periods of cooling were also detected, registered in the Late Cretaceous/ Paleocene and Eocene, driven as much by uplift with tectonic denudation as by faulting. The nearest portion of the edge of the basin (external to the Dome of Pitanga), registered a period of warming over the Paleocene that can be attributed to the increase in the geothermal gradient. The periods of cooling have a regional and temporal relationship with the tectonic events that occurred in the southeastern Brazil and were described in the crystalline basement. The period of warming, registered in the Late Cretaceous/ Paleocene, has local occurrence and can be found only in the southern portion of the studied area.

Corpus Luteum Development and Function after Supplementation of Long-Acting Progesterone During the Early Luteal Phase in Beef Cattle

Contents: Strategic supplementation of P4 may be used to increase conception rates in cattle, but timing of supplementation in relation to ovulation, mass of supplementary P4 and formulation of the P4-containing supplement has not been determined for beef cattle. Effects of supplementation of long-acting progesterone (P4) on Days 2 or 3 post-ovulation on development, function and regression of corpus luteum (CL) were studied in beef cattle. Cows were synchronized with an oestradiol/P4-based protocol and treated with 150 or 300 mg of long-acting P4 on Day 2 or 3 post-ovulation (6-7 cows/group). Colour-doppler ultrasound scanning and blood sample collection were performed from Day 2-21.5. Plasma P4 concentrations were greater (p < 0.05) from Day 2.5-5.5 in the Day 2-treated groups and from Day 3.5-5.5 in the Day 3-treated cows than in the control group. CL area and blood flow during Day 2-8.5 did not differ (p > 0.05) among groups, suggesting no effect of P4 treatment on luteal development. The frequency of cows that began luteolysis before Day 15 was greater (p < 0.04) in cows treated with 300 mg than in the controls, but there were no differences between non-treated and 150 mg-treated cows. The interval from pre-treatment ovulation to functional and structural luteolysis was shorter (p < 0.01) in the combined P4-treated groups than in the control cows. In conclusion, was showed for the first time that long-acting P4 supplementation on Day 2 or 3 post-ovulation increases P4 concentrations for ≥3 day, has no effect on luteal development, but anticipates the beginning of luteolysis in beef cattle. © 2013 Blackwell Verlag GmbH.

O evangelho de Maria e a participação feminina nas comunidades gnósticas cristãs do II século

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

“Brasil mostra a tua cara”: rock nacional, mídia e a redemocratização política (1982-1989)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)