Santé mentale, alcool/drogues et violence : adaptation du modèle tripartite de Goldstein.

Plusieurs recherches démontrent que le fait de présenter un trouble mental sévère et un trouble concomitant lié à une substance serait associé à un risque plus élevé de comportements violents. Toutefois, il n’existe aucun modèle conceptuel expliquant la relation entre ce type de comorbidité psychiatrique et la violence. Cet article propose une première explication du phénomène basée sur une adaptation des volets psychopharmacologique et économicocompulsif du modèle tripartite de Goldstein, à la population atteinte d’un trouble mental sévère et persistant (la schizophrénie ou la maladie bipolaire) et d’un trouble concomitant lié à une substance.

Amino acid substitutions in σ1 and μ1 outer capsid proteins are selected during mammalian reovirus adaptation to Vero cells

Establishment of viral persistence in cell culture has previously led to the selection of mammalian reovirus mutants, although very few of those have been characterized in details. In the present study, reovirus was adapted to Vero cells that, in contrast to classically-used L929 cells, are inefficient in supporting the early steps of reovirus uncoating and are also unable to produce interferon as an antiviral response once infection occurs. The Vero cell-adapted reovirus exhibits amino acids substitutions in both the σ1 and μ1 proteins. This contrasts with uncoating mutants from persistently-infected L929 cells, and various other cell types, that generally harbor amino acids substitutions in the σ3 outer capsid protein. The Vero cell-adapted virus remained sensitive to an inhibitor of lysosomal proteases; furthermore, in the absence of selective pressure for its maintenance, t he virus has partially lost its ability to resist interferon. The positions of the amino acids substitutions on the known protein structures suggest an effect on binding of the viral σ1 protein to the cell surface and on μ1 disassembly from the outer capsid.

Traduction et adaptation d’un module d’introduction à la gestion des données de recherche

Présentation-éclair, Congrès des milieux documentaires du Québec 2015

Science, gender and otherness in Shelley's Frankenstein and Kenneth Branagh's film adaptation

Questions of gender and genre in Frankenstein remain complex issues for contemporary critics, in the novel itself as well as in its cinematographic adaptations, from John Whale's classic 1931 version to Kenneth Branagh's 1994 "Mary Shelley's Frankenstein." Though science seems to be the unifying principle behind the main story of the novel and the films, I will argue that Shelley incorporates science and sexual orientation within her novel in a way that differs significantly from the films, and especially from Branagh's version.

Predicted impact of the sea-level rise at VellareColeroon estuarine region of Tamil Nadu coast in India: Mainstreaming adaptation as a coastal zone management option

Low-lying coastal areas are more vulnerable to the impacts of climate change as they are highly prone for inundation to SLR (Sea-Level Rise). This study presents an appraisal of the impacts of SLR on the coastal natural resources and its dependent social communities in the low-lying area of VellareColeroon estuarine region of the Tamil Nadu coast, India. Digital Elevation Model (DEM) derived from SRTM 90M (Shuttle Radar Topographic Mission) data, along with GIS (Geographic Information System) techniques are used to identify an area of inundation in the study site. The vulnerability of coastal areas in Vellar-Coleroon estuarine region of Tamil Nadu coast to inundation was calculated based on the projected SLR scenarios of 0.5 m and 1 m. The results demonstrated that about 1570 ha of the LULC (Land use and Land cover) of the study area would be permanently inundated to 0.5 m and 2407 ha for 1 m SLR and has also resulted in the loss of three major coastal natural resources like coastal agriculture, mangroves and aquaculture. It has been identified that six hamlets of the social communities who depend on these resources are at high-risk and vulnerable to 0.5 m SLR and 12 hamlets for 1 m SLR. From the study, it has been emphasized that mainstreaming adaptation options to SLR should be embedded within a coastal zone management and planning effort, which includes all coastal natural resources (ecosystem-based adaptation), and its dependent social communities (community-based adaptation) involved through capacity building

Agricultural, architectural and archaeological evidence for the role and ecological adaptation of a scattered mountain oasis in Oman

The recent discovery of the monumental 5000 years old tower tombs on top of the up to 1850 m high Shir plateau has raised numerous questions about the economic and infrastructural basis of the agro-pastoral-piscicultural society which likely has constructed them. The scattered oasis settlement of Maqta, situated just below the towers in a rugged desert environment has therefore been studied from 2001 to 2003 to understand its prehistoric and present role along the ancient trade route which connected the inner-Omani Sharqiya across the southern Hajar mountains with the ocean port of Tiwi. Maqta consists of a central area with 59 buildings and 12 scattered temporary settlements comprising a total of about 200 semi-nomadic inhabitants and next to 900 sheep and goats. The 22 small springs with a flow rate between 5 and 1212-l h^-1 are watering 16 terrace systems totaling 4.5 ha of which 2.9 ha are planted to date palms (Phoenix dactylifera L.), 0.4 ha to wheat landraces (Triticum durum and Triticum aestivum) during the cooler winter months, 0.4 are left fallow and 0.8 h are abandoned. During a pronounced drought period from 2001 to 2003, the springs’ flow rate declined between 38% and 72%. Most of the recent buildings of the central housing area were found empty or used as temporary stores by the agro-pastoral population watching their flocks on the surrounding dry mountains. There is no indication that there ever was a settlement older than the present one. A number of Hafit (3100–2700 BC) and Umm an-Nar (2700–2000 BC) tombs just above the central housing area and further along one of the trade routes to the coast are the only indication of an old pastoral landuse in Maqta territory where oasis agriculture may have entered only well after 1000 AD. With this little evidence of existence during the 3rd millennium BC, Maqta is unlikely to have played any major role favouring the construction of the nearby monumental Shir tower tombs other than providing water for herders and their flocks, early migrant traders or tower tomb constructors.

Assessing adaptation – Climate change and indigenous livelihood in the Andes of Bolivia

Based on a case study of Charazani – Bolivia, this article outlines the understanding of adaptive strategies to cope with climate change and its impact on environmental and socioeconomic conditions that are affecting rural livelihoods. Mainly qualitative methods were used to collect and analyze data following the framework for vulnerability assessments of a socio-ecological system. Climate data reveals an increase of precipitation and temperature during the last decades. Furthermore the occurrence of extreme weather events, particularly drought, frost, hailstorms and consequently landslides and fire are increasing. Local testimonies highlight these events as the principle reasons for agricultural losses. This climatic variability and simultaneous social changes were identified as the drivers of vulnerability. Yet, several adaptive measures were identified at household, community and external levels in order to cope with such vulnerability; e.g. traditional techniques in agriculture and risk management. Gradually, farmers complement these activities with contemporary practices in agriculture, like intensification of land use, diversification of irrigation system and use of artificial fertilizers. As part of a recent trend community members are forced to search for new off-farm alternatives beyond agriculture for subsistence. Despite there is a correspondingly large array of possible adaptation measures that families are implementing, local testimonies point out, that farmers often do not have the capacity and neither the economical resources to mitigate the risk in agricultural production. Although several actions are already considered to promote further adaptive capacity, the current target is to improve existing livelihood strategies by reducing vulnerability to hazards induced by climate change.

Determinants of climate change adaptation strategies used by rice farmers in Southwestern, Nigeria

Poor adaptation to climate change is a major threat to sustainable rice production in Nigeria. Determinants of appropriate climate-change adaptation strategies used by rice farmers in Southwestern Nigeria have not been fully investigated. In this study, the determinants of climate change adaptation strategies used by rice farmers in Southwestern Nigeria were investigated. Data were obtained through Focus Group Discussions (FGDs) and field survey conducted in the study areas. Data obtained were analyzed using descriptive and inferential statistical tools such as percentage and regression analysis. The major climate change adaptation strategies used by the respondents included; planting improved rice variety such as Federal Agricultural Research Oryza (FARO) (80.5 %), seeking early warning information (80.9 %), shifting planting date until the weather condition was favourable (99.1 %), and using chemical fertilizer on their farms in order to maintain soil fertility (20.5 %). The determinants of climate change adaptation strategies used by the farmers, included access to early warning information (β=43.04), access to fertilizer (β=5.78), farm plot size (β=–12.04) and access to regular water supply (β=–24.79). Climate change adaptation required provision of incentives to farmers, training on drought and flood control, and the use of improved technology to obtain higher yield.

Ecosystem services and adaptation for agriculture and food security: analysis of two decades (1991–2011) of financing by the Global Environment Facility

Investing in global environmental and adaptation benefits in the context of agriculture and food security initiatives can play an important role in promoting sustainable intensification. This is a priority for the Global Environment Facility (GEF), created in 1992 with a mandate to serve as financial mechanism of several multilateral environmental agreements. To demonstrate the nature and extent of GEF financing, we conducted an assessment of the entire portfolio over a period of two decades (1991–2011) to identify projects with direct links to agriculture and food security. A cohort of 192 projects and programs were identified and used as a basis for analyzing trends in GEF financing. The projects and programs together accounted for a total GEF financing of US$1,086.8 million, and attracted an additional US$6,343.5 million from other sources. The value-added of GEF financing for ecosystem services and resilience in production systems was demonstrated through a diversity of interventions in the projects and programs that utilized US$810.6 million of the total financing. The interventions fall into the following four main categories in accordance with priorities of the GEF: sustainable land management (US$179.3 million), management of agrobiodiversity (US$113.4 million), sustainable fisheries and water resource management (US$379.8 million), and climate change adaptation (US$138.1 million). By aligning GEF priorities with global aspirations for sustainable intensification of production systems, the study shows that it is possible to help developing countries tackle food insecurity while generating global environmental benefits for a healthy and resilient planet.

Guia per a l'adaptació a l'espai europeu d'educació superior: 1. Competències = Guía para la adaptación al espacio europeo de educación superior: 1. Competencias = Guide to adaptation to the european higher education area: 1. Competences

Aquest quadern és el primer lliurement de les Orientacions per a l’adaptació a l’espai europeu d’educació superior. Té l’origen en el debat de la Comissió de seguiment del Pla pilot d’adaptació a l’espai europeu d’educació superior de la UdG i del grup de treball que s’ha constituït l’hivern 2005-2006 expressament per tractar el tema de les competències

Guia per a l'adaptació a l'espai europeu d'educació superior: 2. Competències UdG = Guía para la adaptación al espacio europeo de educación superior: 2. Competencias UdG = Guide to Adaptation to the European Higher Education Area: 2. UdG competences

Aquest quadern forma part de la Guia per a l'adaptació a l'espai europeu d'educació superior

Guia per a l'adaptació a l'espai europeu d'educació superior: 3. El vostre paper, estudiants = Guía para la adaptación al espacio europeo de educación superior: 3. Vuestro papel, estudiantes = Guide to adaptation to the European Higher Education Area: 3. Your role as a student

Aquest quadern forma part de la Guia per a l'adaptació a l'espai europeu d'educació superior

Guia per a l'adaptació a l'espai europeu d'educació superior: 4. Activitats d'aprenentatge = Guía para la adaptación al espacio europeo de educación superior: 4. Actividades de aprendizaje = Guide to Adaptation to the European Higher Education Area: 4. Learning Activities

Aquest quadern és el quart lliurement de la Guia per a l'adaptació a l'espai europeo superior. Té l'origen en el debat de la Comissió de Seguiment del Pla Pilot d'adaptació a l'Espai Europeu d'Educació Superior de la UdG i del grup de treball que s'ha constituït l'estiu del 2006 expressament per tractar el tema de les activitats d'aprenentatge

Guia per a l'adaptació a l'espai europeu d'educació superior: 5. Avaluació de l'aprenentatge = Guía para la adaptación al espacio europeo de educación superior = Guide to Adaptation to the European Higher Education Area

Aquest quadern és el cinquè lliurement de la Guia per a l'adaptació a l'espai europeu d'educació superior. Té l'origen en el debat de la Comissió de Seguiment del Pla pilot d'Adaptació a l'Espai Europeu d'Educació Superior de la UdG i del grup de treball que s'ha constituït expressament per tractar el tema de l'avaluació dels aprenentatges

Guia per a l'adaptació a l'espai europeu d'educació superior: 6. Continguts = Guía para la adaptación al espacio europeo de educación superior: 6. Contenidos = Guide to Adaptation to the European Higher Education Area: 6. Contents

Aquest quadern és el sisè lliurament de la Guia per a l'adaptació a l'espai europeu d'educació superior. Té l'origen en el debat de la Comissió de Seguiment del Pla Pilot d'Adaptació a l'Espai Europeu d'Educació Superior de la UdG i del grup de treball que s'ha constituït expressament per tractar el tema de l'avaluació dels aprenentatges