The economic impact of progressive neurological illness on quality of life in Australia

The current study examined the impact of financial costs and self-reported economic pressure on the quality of life of patients with progressive neurological illness. Participants were 423 people from four illness groups in Australia. Participants completed measures of: 1. quality of life, 2. income, 3. expenses, 4. economic pressure, 5. social support, 6. relationship satisfaction, and 7. severity of illness. There was a strong negative association between quality of life and economic pressure (but not income or expenses) for all groups. Subjective assessment of economic pressure was strongly associated with quality of life for people with motor neurone disease and multiple sclerosis. Implications of these results for assisting people with progressive neurological illnesses to cope with the financial changes that occur due to their illness are discussed.

Influence of grain supplements during winter on liveweight, mohair growth and mohair quality of weaner Angora goats

To identify methods to improve growth and mohair production of weaned Angora goats (mean liveweight 18-20 kg) during their first winter, two supplementary feeding experiments using whole-grain barley and lupins were conducted on a farm in southern New South Wales, in a region where weaner illthrift had been reported. Experiment 1 was a 2×2 + 1 factorial with 16 replicate goats; two feeding levels (115 or 230 g/day of whole-barley grain)× two periods of feeding (4 or 8 weeks) + Control (grazing only). Experiment 2 had five treatments × 13 replicate goats; three treatments fed 230 g/day of whole-barley grain for periods of 2 or 3 months and two treatments fed a 50:50 mixture of lupin and barley grain at 350 g/day for 2 or 4 months. Goats were individually fed and then all returned together for grazing. There were no effects of feeding in Experiment 1 and variations of feeding 230 g/day of barley in Experiment 2 provided no benefit. Feeding lupin/barley for 4 months increased liveweight (gain 59 g/day), mohair production, mohair fibre diameter and the incidence of medullated fibre. About 25% of this ration was not eaten by eight goats, reducing treatment average intake to 295 g/day. By the end of spring, there was no difference in treatment liveweights. Regression constants indicated that for each 1 μm increase in mean fibre diameter, greasy fleece weight increased 35 g and for each 1 kg increase in pre-shearing liveweight, greasy fleece weight increased 26 g. The results show that Angora weaner goats can grow during winter, provided their energy and protein needs for growth are met. Improved pasture management and higher levels of supplementary feeding to weaned Angoras are indicated compared with current practices on farms in Australia.

The effect of resistance training on functional capacity and quality of life in individuals with high and low number of metabolic risk factors

OBJECTIVE—There are limited data on the effects of resistance training on the capacity to perform activities of daily living (ADLs) and quality of life (QoL) for individuals with a high number of metabolic risk factors (HiMF). In this study, we examined the effect of resistance training on the capacity to perform ADLs and QoL in individuals with HiMF and compared any benefits with individuals with a low number of metabolic risk factors (LoMF).

RESEARCH DESIGN AND METHODS—Fifty-five untrained individuals, aged 50.8 ± 6.5 years, were randomized to four groups: HiMF training (HiMFT), HiMF control, LoMF training (LoMFT), and LoMF control. At baseline and after 10 weeks of resistance training, participants underwent anthropometric measurements and assessments of aerobic power (Vo2peak), muscle strength, capacity to perform ADLs, and a self-perceived QoL questionnaire. A repeated-measures ANOVA was used to examine the effect of training over time among groups.

RESULTS—Training increased lean body mass in both HiMFT (P = 0.03) and LoMFT (P = 0.03) groups. Total fat content and Vo2peak improved in the LoMFT group only. Muscle strength improved in both training groups (P < 0.01). Time to complete ADLs was reduced by 8.8% in the LoMFT group (P < 0.01) and 9.7% in the HiMF group (P < 0.01). Only the HiMFT group reported improvement in QoL.

CONCLUSIONS— Resistance training improved muscle strength and the capacity to perform ADLs in individuals with HiMF and LoMF. Resistance training improved QoL for the HiMF group, and this result was independent of changes in body fat content or aerobic power. Longer training regimens may be needed to improve QoL in individuals with LoMF.

Functional capacity and quality of life in middle-age men and women with high and low number of metabolic risk factors

It is not clear if men and women with high numbers of risk factors (HiMF) for metabolic syndrome (MetS) have impaired capacities to perform activities of daily living (ADL's) and lower quality of life (QoL) in the absence of symptomatic heart disease. Our results indicate that in women there is a correlation between the number of risk factors and the capacity to perform ADL's and QoL. This was not evident for men. These findings may partly explain why women tend to consult healthcare practitioners earlier in the disease process than men.

The role of attachment in current and future parent caregiving

Few studies have investigated how attachment bonds between older parents and their adult children influence adult children’s provision of care and older parents’ seeking of support from kin. The aim of this study was to investigate how the attachment orientations of adult children (N = 119) and older parents (N = 148) predict family caregiving and perceptions of carer burden. Across both samples (that were unrelated), attachment dimensions were associated with current and future caregiving and care receiving and perceptions of carer burden, even when accounting for demographic variables, parental dependence and filial obligation. Specifically, attachment avoidance was associated negatively with adult children’s future care of parents and positively with burden. In contrast, attachment anxiety was positively associated with older parents’ seeking current support, perceptions of carer burden, and intentions to seek future support.

Health-related quality of life and functioning in bipolar disorder : the impact of pharmacotherapy

Bipolar disorder has a major deleterious impact on many aspects of a patient's functioning and health-related quality of life. Although the formal measurement of these deficits has been neglected until recently, many well-designed trials now include an assessment of functioning and health-related quality of life using one or more rating scales. This review describes recent developments in the measurement of functioning and health-related quality of life in bipolar disorder, and discusses the evidence that medications that improve symptoms in bipolar disorder also offer clinically relevant benefits in functioning and health-related quality of life. Direct comparisons of the benefits of medications including atypical antipsychotics are problematic due to differences in trial populations, study durations and rating scales. Data from quetiapine trials indicate that this medication offers prompt and sustained improvement of functioning in patients with mania and enhancement of health-related quality of life in patients with bipolar depression, to accompany the significant improvements in mood episodes.