[Voyage en Italie : 1824-1830]. , de l'Arc de Titus à Rome. Sur une Echelle de 008 P.M : [élévation partielle et coupe verticale d'une des piles de l'arc, au niveau d'une table ; profil du soubassement] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 495

[Voyage en Italie : 1824-1830]. , Portique connu sous le nom de Bains de Paul Emile. Sur une Echelle de 0,10 P.M. : [coupe, deux élévation principale et latérale partielles, quatre plans, détail d'une pierre] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 597

[Voyage en Italie : 1824-1830]. , Cour du Palais de Venise, à Rome. Sur une Echelle de 0,010 P.M. : [élévation avec coupe sur une galerie] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 582

[Voyage en Italie : 1824-1830]. , Palais de Venise. Croisée du 1er Etage. Sur une Echelle de 0,050 P.M. : [élévation et coupe d'une fenêtre] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 585

Catalogue d'une collection de bons tableaux... par suite du décès de M. X... [Rossard, De Courbonne] / [expert] Febvre

[Vente. Art. 1857-12-24. Paris]

[Voyage en Italie : 1824-1830]. , Tombeau de Bibulus à Rome. Sur une Echelle de 0,025 P.M. : [élévation, plan partiel] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 607

Evolutionary history of the greater white-toothed shrew (Crocidura russula) inferred from analysis of mtDNA, Y, and X chromosome markers.

We investigate the evolutionary history of the greater white-toothed shrew across its distribution in northern Africa and mainland Europe using sex-specific (mtDNA and Y chromosome) and biparental (X chromosome) markers. All three loci confirm a large divergence between eastern (Tunisia and Sardinia) and western (Morocco and mainland Europe) lineages, and application of a molecular clock to mtDNA divergence estimates indicates a more ancient separation (2.25 M yr ago) than described by some previous studies, supporting claims for taxonomic revision. Moroccan ancestry for the mainland European population is inconclusive from phylogenetic trees, but is supported by greater nucleotide diversity and a more ancient population expansion in Morocco than in Europe. Signatures of rapid population expansion in mtDNA, combined with low X and Y chromosome diversity, suggest a single colonization of mainland Europe by a small number of Moroccan shrews >38 K yr ago. This study illustrates that multilocus genetic analyses can facilitate the interpretation of species' evolutionary history but that phylogeographic inference using X and Y chromosomes is restricted by low levels of observed polymorphism.

Catalogue d'une collection de tableaux anciens... provenant du cabinet de M. X***,... / [expert] Febvre

[Vente. Art. 1859-05-20. Paris]

Fast Geodesic Active Fields for Image Registration Based on Splitting and Augmented Lagrangian Approaches.

In this paper, we present an efficient numerical scheme for the recently introduced geodesic active fields (GAF) framework for geometric image registration. This framework considers the registration task as a weighted minimal surface problem. Hence, the data-term and the regularization-term are combined through multiplication in a single, parametrization invariant and geometric cost functional. The multiplicative coupling provides an intrinsic, spatially varying and data-dependent tuning of the regularization strength, and the parametrization invariance allows working with images of nonflat geometry, generally defined on any smoothly parametrizable manifold. The resulting energy-minimizing flow, however, has poor numerical properties. Here, we provide an efficient numerical scheme that uses a splitting approach; data and regularity terms are optimized over two distinct deformation fields that are constrained to be equal via an augmented Lagrangian approach. Our approach is more flexible than standard Gaussian regularization, since one can interpolate freely between isotropic Gaussian and anisotropic TV-like smoothing. In this paper, we compare the geodesic active fields method with the popular Demons method and three more recent state-of-the-art algorithms: NL-optical flow, MRF image registration, and landmark-enhanced large displacement optical flow. Thus, we can show the advantages of the proposed FastGAF method. It compares favorably against Demons, both in terms of registration speed and quality. Over the range of example applications, it also consistently produces results not far from more dedicated state-of-the-art methods, illustrating the flexibility of the proposed framework.

Bulla innovationis litterarū Contra invadentes hostiliter Terras & Loca. S. R. E. ac Monitorii penalis Cōtta Iniquitatis Filium Franciscū Mariā. Le Ruuene Et eius sequaces & fautores & Consilium p̄titores machinates cuadere Terras S. R... (Janvier 1517.)

[Acte pontifical. 1517-01-00]

Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for retinoid X receptor. Possible role of a leucine zipper-like heptad repeat.

The peroxisome proliferator-activated receptors (PPAR) and thyroid hormone receptors (TR) are members of the nuclear receptor superfamily, which regulate lipid metabolism and tissue differentiation. In order to bind to DNA and activate transcription, PPAR requires the formation of heterodimers with the retinoid X receptor (RXR). In addition to activating transcription through its own response elements, PPAR is able to selectively down-regulate the transcriptional activity of TR, but not vitamin D receptor. The molecular basis of this functional interaction has not been fully elucidated. By means of site-directed mutagenesis of hPPAR alpha we mapped its inhibitory action on TR to a leucine zipper-like motif in the ligand binding domain of PPAR, which is highly conserved among all subtypes of this receptor and mediates heterodimerization with RXR. Replacement of a single leucine by arginine at position 433 of hPPAR alpha (L433R) abolished heterodimerization of PPAR with RXR and consequently its trans-activating capacity. However, a similar mutation of a leucine residue to arginine at position 422 showed no alteration of heterodimerization, DNA binding, or transcriptional activation. The dimerization deficient mutant L433R was no longer able to inhibit TR action, demonstrating that the selective inhibitory effect of PPAR results from the competition for RXR as well as possibly for other TR-auxiliary proteins. In contrast, abolition of DNA binding by a mutation in the P-box of PPAR (C122S) did not eliminate the inhibition of TR trans-activation, indicating that competition for DNA binding is not involved. Additionally, no evidence for the formation of PPAR:TR heterodimers was found in co-immunoprecipitation experiments. In summary, we have demonstrated that PPAR selectively inhibits the transcriptional activity of TRs by competition for RXR and possibly non-RXR TR-auxiliary proteins. In contrast, this functional interaction is independent of the formation of PPAR:TR heterodimers or competition for DNA binding.

Essai de grammaire universelle, ou Analyse générale des langues réduites à leurs radicaux, et traduites les unes aux autres au moyen d'une hémi-pasigraphie claire et simple. Rapport sur la méthode pasigraphique de M. Jônain, présenté à la Société philomathique de Bordeaux (2e édition considérablement revue, corrigée...) / par P. Jônain,... ; [signé La Harpe fils, rapporteur]

Comprend : Rapport sur la méthode pasigraphique de M. Jônain, présenté à la Société philomathique de Bordeaux