Interaction of scopolamine and cholesterol with sphingomyelin bilayers by FT-Raman spectroscopy

The interaction of scopolamine and cholesterol with sphingomyelin bilayers has been investigated by FT-Raman spectroscopy in head-group region (600-1000 cm(-1)), the C-C stretching (1000-1200 cm(-1)), CH2 deformation (1400-1500 cm(-1)) and the C-H stretching (2800-3000 cm(-1)) mode regions. The results indicate that scopolamine and cholesterol do not change the conformation of O-C-C-N+ backbone in the choline group of sphingomyelin bilayers, the polar headgroup is still extending parallel to the bilayer surface and O-C-C-N+ group is still in its gauche conformer. Scopolamine and cholesterol lower the order of the interface, the interchain, CH2 crystal lattices and the lateral chain-chain packing, and increase their fluidity.

Crystal structure of polypropylene filled with rare earth oxides

The effect of a fine powder of Y2O3, Nd2O3, and Ho2O3 on the crystal structure of isotactic polypropylene (iPP) was studied with WAXD and DSC techniques. The results showed that the addition of the three rare earth oxides (REOs) can increase the crystallite size of the alpha-form crystal and the degree of crystallinity of iPP at an annealing temperature of 120 degrees C and that both Y2O3 and Nd2O3 are the beta-nucleator of iPP. REOs enhance the overall growth rate of the spherulites of iPP. All the iPP samples filled with REOs which were crystallized isothermally at 132 degrees C from the melt exhibited their melting peaks of the beta-form on the DSC heating traces, indicating that the REOs are the nucleating agents for both the alpha- and beta-forms of iPP under isothermal conditions. (C) 1996 John Wiley & Sons, Inc.

MOLECULAR CHARACTERISTICS AND CRYSTALLINE-STRUCTURE OF ETHYLENE-DIMETHYLAMINOETHYL-METHACRYLATE COPOLYMERS

The relationship between molecular and crystalline structural characteristics of the ethylene -dimethylaminoethylmethacrylate copolymers (EDAM) was investigated and related to melt flow index MI and average gross content of DAM comonomer, in comparison with low density polyethylene (LDPE) produced by the common high-pressure radical polymerization process. Although the average molecular weight and its distribution are influenced predominantly by the polymerization conditions, DAM-content seems not to depend significantly on molecular weight according to the GPC-FT/IR measurement. Comonomer sequence distributions were determined quantitatively with the C-13-NMR spectra entirely assigned by DEPT and H-1-C-13 COSY techniques. The result suggests the alternating copolymerization tendency and surprisingly coincides with the simulation out-puts based on the assumption of continuous complete mixing reactor model, using Mayo-Lewis equation and the same Q-e values as previously reported on different types of copolymers such as EVA and St.DAM (VA;vinylacetate, St;styrene). It was confirmed by WAXD and SAXS analyses that the crystallinity X(c) and the thickness of lamellar crystal l(c) decreased with increasing DAM-content, whereas the a-lattice and b-lattice dimensions enlarged. X(c) and l(c) can definitely be correlated to the heats of fusion and crystallization measured by DSC. The average size of spherulites measured with light scattering photometry tends to be enlarged with decreasing molecular weight (increasing MI) and DAM-content.

STUDY ON STRUCTURE-PROPERTY RELATIONSHIP OF POLYIMIDE BLENDS .2. STRUCTURE AND MISCIBILITY OF POLYIMIDE PBPI-E/PTI-E BLENDS

The structure and miscibility of polyimide PBPI-E/PTI-E blends were studied by wide- and small-angle X-ray scattering and dynamic mechanical analysis, where PBPI-E is a biphenyl-dianhydride-based polyimide, and PTI-E is a polyimide from 4,4'-thiodiphthalic anhydride and 4,4'-oxydianiline. The results obtained show that there exists a paracrystalline structure in the blends with high content of PBPI-E, but this does not affect the miscibility of the blends. The blends are miscible over the entire composition range, since only one T(g) was observed for each blend. Meanwhile, the segregation of PTI-E during crystallization of PBPI-E in the blends is interlamellar.

Transformation of accommodation space of the Cretaceous Qingshankou Formation, the Songliao Basin, NE China

Analysis of accommodation space variation during deposition of the Cretaceous Qingshankou Formation in the Songliao Basin, NE China, indicates that accommodation space changed both through time and across the basin as a seesaw movement. The mid-upper Qingshankou Formation is divided into three units. In each unit, changes of accommodation space differ in the southern and northern part of the basin. Increasing accommodation in the southern part is accompanied by a decrease in the northern part, and vice versa. Between the northern and southern basin, there was a neutral belt that is like a fulcrum, called the transformation belt here, where the accommodation did not change to any significant degree. We call this response 'accommodation transformation', whose characteristics are defined by tectonic subsidence analysis, palaeontological and sedimentary analyses. The accommodation increasing belt, decreasing belt, transformation belt and accommodation transformation boundary together constitute the accommodation transformation system. The recognition of accommodation transformation in the Songliao Basin provides a new insight into sequence stratigraphy and might be widely applicable.

Minor sesquiterpenes with new carbon skeletons from the brown alga Dictyopteris divaricata

Five minor sesquiterpenes (1-5) with two novel carbon skeletons, together with a minor new oplopane sesquiterpene ( 6), have been isolated from the brown alga Dictyopteris divaricata. By means of spectroscopic data including IR, HRMS, 1D and 2D NMR, and CD, their structures including absolute configurations were assigned as (+)-(1R, 5S, 6S, 9R)3- acetyl-1-hydroxy-6-isopropyl-9-methylbicyclo[4.3.0] non-3-ene ( 1), (+)-(1R, 3S, 4S, 5R, 6S, 9R)-3-acetyl-1,4-dihydroxy-6- isopropyl-9-methylbicyclo[4.3.0] nonane (2), (+)-(1R, 3R, 4R, 5R, 6S, 9R)-3-acetyl-1,4-dihydroxy-6-isopropyl-9-methylbicyclo[ ;4.3.0] nonane ( 3), (+)-(1S, 2R, 6S, 9R)-1-hydroxy-2-(1-hydroxyethyl)-6-isopropyl-9-methylbicyclo[4.3.0] non-4-en-3-one (4), (-)-( 5S, 6R, 9S)-2-acetyl-5-hydroxy-6-isopropyl-9-methylbicyclo[4.3.0] non-1-en-3-one ( 5), and (-)-( 1S, 6S, 9R)- 4-acetyl- 1-hydroxy-6-isopropyl-9-methylbicyclo[ 4.3.0] non-4-en-3-one ( 6). Biogenetically, the carbon skeletons of 1-6 may be derived from the co-occurring cadinane skeleton by different ring contraction rearrangements. Compounds 1-6 were inactive (IC50 > 10 mu g/mL) against several human cancer cell lines.

CIM-OSA的思想及其应用

计算机集成制造系统开放式体系结构 CIM-OSA 是欧共体 ESPRIT 计划的 AMICE 协作体的研究成果,本文系统地介绍了 CIM-OSA 的内容及特点,并对 CIM-OSA 思想的应用实例 IMPACS(集成制造计划和控制系统)和 IBM 的 CIM 结构做了详细分析和阐述.

分布式问题求解在CIMS中的应用

本文介绍了一个应用于 CIMS 的分布式智能系统,该系统将 CAD,CAPP,CAM 有机地集成为一体.由于采用了分布式问题求解技术、通讯技术,使在不同地理位置上的计算机性能和资源得以充分发挥和利用.多个处理结点组成的基于黑板结构的分布式智能系统,可以高速、并行地执行分散在不同结点的知识源,提高系统的灵活性和处理能力.运行在三个结点(可扩充多个)的系统大体相同.主要包括:知识获取子系统、前端处理(负责接收与发送)、任务的分解、任务的评估与分配、任务的综合、后端处理(子问题求解)模块以及解释子系统.目前该系统已在由以太网连接的 SUN 计算机上运行,分布式智能系统本身由 C 语言写成,被集成的子系统由 C 和 FORTRAN 两种语言写成.

层控夕卡岩型矿床成矿系统的元素活动性及质量迁移——以铜陵冬瓜山铜矿床为例

应用改善了的质量平衡方程研究冬瓜山层控夕卡岩型铜矿床成矿系统的元素活动性及质量迁移,结果表明:系统中Zr ,Hf ,Y和Nb 为不活动元素,其余均为活动元素。主量元素中仅CaO 为迁出组分,其质量迁移量为84 % ,其余均为带入组分,带入量最大的SiO2 的质量迁移量高达2384 %;稀土元素均为带入组分,其中,中稀土较轻稀土和重稀土的活动性更强;其它微量元素中,带入序列由强到弱为:Cr →Ta →Sn →Th ,迁出序列由强至弱依次为:U →Sb →Ni →Sr →Ba →Rb →Co →W;成矿元素Cu 和Ag 为带入组分,其中Cu 的带入量最大,质量迁移量高达1200 %。本文还得出两点具普适性认识: ①稀土元素较其它微量元素对体系条件的变化更为敏感,且往往表现出明显的规律性变化,能更好地示踪地质地球化学过程。②不同元素在不同体系中的行为特征差异极大,仅凭经验判定某一元素为不活动元素往往不可靠。因此,在开展质量平衡研究时,首先采用适当方法确认体系的不活动元素是一项不可或缺的前提工作。

地幔流体作用——地幔捕虏体中流体包裹体的研究

被碱性玄武岩和金伯利岩带到地表的地幔捕虏体是认识地球深部信息的窗口，是人们能够直接观察到的一种上地幔样品，其矿物中流体包裹体的存在提供了上地幔流体活动的直接证据。流体／地幔矿物之间元素的分配对约束地幔变代过程中流体相的作用和上地幔流体的组成，揭示俯冲带壳幔物质的再循环过程，解释岛弧玄武岩高场强元素亏损的原因有重要意义。文章对近年来有关地幔捕虏体中流体包裹体的研究进行了评述，并结合近年来流体／地幔矿物之间元素分配的高温高压实验研究讨论了流体在地幔中的重要作用。

A Want of Order and Good Discipline: Rules, Discretion and the Victorian Prison

null RAE2008