953 resultados para Laitinen, Lea: Sanan voima
Resumo:
Este estudo teve como questão de pesquisa verificar se há evidência de progressão na avaliação final dos Jogos Desportivos Colectivos de invasão, mantendo o protocolo de avaliação inicial, utilizando as Provas de Avaliação Aferida, aplicadas na Escola Secundária Dona Luísa de Gusmão (ESDLG). Como contributo à aplicação e sustentabilidade das Provas apresentamos um levantamento dos níveis introdução e elementar do Programa, em que destacamos princípios comuns que possam beneficiar a clarificação do currículo para os professores avaliadores e contribuir para o ensino dos jogos desportivos. O presente trabalho assume-se como um estudo exploratório de caso, em que se escolheu uma turma específica de oitavo ano da ESDLG, com vinte e seis sujeitos envolvidos no caso. Isto para estudar a filosofia de aplicação das Provas de Avaliação, em que a sua operacionalização é da responsabilidade do Grupo de Educação Física. Os resultados apontam para a progressão do nível de desempenho dos alunos nas matérias de Andebol, Basquetebol e Futebol. A avaliação nos jogos desportivos colectivos da ESDLG está de acordo com as orientações dos PNEF. O estudo é válido pela representação que as Provas têm nos objectivos definidos nos Programas Nacionais de Educação Física e obedece a níveis de fidelidade pela constância apresentada nas observações realizadas pelos professores nos dois momentos de avaliação. Importa também referir que as Provas de Avaliação alicerçam a aferição de critérios, moderam a avaliação dos alunos e permitem ao Agrupamento de Educação Física tomar decisões mediante os resultados e tendências das Provas. Para que a avaliação possa ser ainda mais objectiva será importante associar às Provas de Avaliação um ensino contextualizado dos jogos desportivos, de modo a que se avalie o aluno nas mesmas condições em que se ensina.
Resumo:
Imbalance is a risk of cochlear implantation. This is particularly important in patients receiving bilateral implants, who are often children. 25 adult and pediatric patients undergoing cochlear implantation were tested pre-operatively and post-operatively using tests of balance function. Results showed moderate losses in some test paradigms following implantation in the patient group as a whole. While changes in balance function due to cochlear implantation are not uncommon, their practical effect on function may be minor.
Resumo:
El presente estudio ejecuta un análisis de la “Nueva Agenda de Seguridad Interna y Externa” propuesta por el Gobierno de la Revolución Ciudadana, proposición que pretende dar un cambio sobre la visión de la política de defensa y el espacio de la seguridad. En este análisis también se examina el cambio de la normativa legal, ya que el mismo se articula desde el enfoque de nuevos principios y nuevos controles desde la ciudadanía. De esta forma, el estudio lo que pretende dar a conocer es: Cuáles son los nuevos mecanismos o dispositivos de Control Civil sobre las Fuerzas Armadas; entendiéndose este Control Civil desde las instituciones del Estado. Dentro del rigor metodológico del estudio, éste se plantea como un trabajo bajo el método comparativo desde las teorías de la seguridad y las teorías institucionales examinando tres lineamientos: “concepto de seguridad, la institucionalidad planteada y; la identificación de actores que participaron en la construcción de la política de defensa.” De esta forma, este estudio considera que los indicadores comparables se dan en la construcción del Libro Blanco y de la NASIE. En tal sentido, quien lea este estudio puede seguir sin conflicto la lógica de la argumentación. En su contenido, la investigación presenta dos capítulos, que se enuncian a continuación: Capítulo I: “LA POLÍTICA DE DEFENSA: DEL LIBRO BLANCO A LA NUEVA AGENDA DE SEGURIDAD INTERNA Y EXTERNA”, en el cual se examina los lineamientos antes mencionados, evidenciando dos paradigmas: la visión estatocéntrico y la visión antropocéntrica de la seguridad, sus cambios y sus continuidades. En el Capítulo II: “COMPARACIÓN DE LA NUEVA INSTITUCIONALIDAD EN LA DEFENSA”, aquí se observa la relación de las FF.AA con el Presidente y con el Parlamento, desde las dos propuestas. Junto a ello se examina el cambio en la Ley de Seguridad Nacional de 1979, a la Ley de Seguridad Pública y del Estado emitida en el año 2009. Finalmente, se expone las conclusiones del trabajo.
Resumo:
This article explores the Foucauldian notions of practices of the self and care of the self, read via Deleuze, in the context of Iyengar yoga (one of the most popular forms of yoga currently). Using ethnographic and interview research data the article outlines the Iyengar yoga techniques which enable a focus upon the self to be developed, and the resources offered by the practice for the creation of ways of knowing, experiencing and forming the self. In particular, the article asks whether Iyengar yoga offers possibilities for freedom and liberation, or whether it is just another practice of control and management. Assessing Iyengar yoga via a ‘critical function’, a function of ‘struggle’ and a ‘curative and therapeutic function’, the article analyses whether the practice might constitute a mode of care of the self, and what it might offer in the context of the contemporary need to live better, as well as longer.
Resumo:
This paper explores the process of learning an embodied knowledge using the work of Dreyfus and Deleuze. Although geographers have begun to acknowledge the role of embodied knowledges in social life, there have been few in-depth case studies of how these skills are learned. This paper offers a case study of Thai Yoga massage (TYM), a ‘complementary and alternative therapy’ which is growing in popularity in the United Kingdom. Having outlined the case study, the paper explores the cultural geographies of the formalisation, documentation and contestation of the set of techniques that have come to cohere in the UK as TYM. The paper then interrogates the messy corporeal geographies of learning a skill, and briefly considers how more advanced practitioners experience their skilled practice.
Resumo:
Post-phenomenological geographies are an emergent (and as yet relatively fragmentary) body of work. This work does not reflect a turn away from phenomenological theories; rather it reflects a critical engagement which rereads them through the post-structuralist theories of such authors as Deleuze, Derrida, and Levinas. This rereading, combined with a disciplinary context of a turn to practice and the ‘more than human’, has resulted in post-phenomenological geographies which extend the boundaries of the phenomenological focus upon the experiencing subject (in place). Thus, the interest is in the ways in which inhuman, nonhuman, and more-than-human forces contribute to processes of subject formation, place making, and inhabiting the world. These geographies have thus far been played out through critical explorations of the realms of the experiencing subject and landscape. This more-than-human focus has tested conventional human geographical methods, requiring innovative use of technologies such as video to document research, the use of experiential research methods, and also experimentation with the form of narrating these experiential methods.
Resumo:
A cellular receptor for the haemagglutinating enteroviruses (HEV), and the protein that mediates haemagglutination, is the membrane complement regulatory protein decay accelerating factor (DAF; CD55). Although primate DAF is highly conserved, significant differences exist to enable cell lines derived from primates to be utilized for the characterization of the DAF binding phenotype of human enteroviruses. Thus, several distinct DAF-binding phenotypes of a selection of HEVs (viz. coxsackievirus A21 and echoviruses 6, 7, 11-13, 29) were identified from binding and infection assays using a panel of primate cells derived from human, orang-utan, African Green monkey and baboon tissues. These studies complement our recent determination of the crystal structure of SCR(34) of human DAF [Williams, P., Chaudhry, Y., Goodfellow, I. G., Billington, J., Powell, R., Spiller, O. B., Evans, D. J. & Lea, S. (2003). J Biol Chem 278, 10691-10696] and have enabled us to better map the regions of DAF with which enteroviruses interact and, in certain cases, predict specific virus-receptor contacts.
Resumo:
Echovirus type 12 (EV12), an enterovirus of the Picornaviridae family, uses the complement regulator, decay-accelerating factor (DAF, CD55) as a cellular receptor. We have calculated a three-dimensional reconstruction of EV12 bound to a fragment of DAF, consisting of short consensus repeat domains 3 and 4, from cryo-negative stain electron microscopy data (EMD #1057). This shows that, as for an earlier reconstruction of the related echovirus type 7 bound to DAF, attachment is not within the viral canyon but occurs close to the two-fold symmetry axes. Despite this general similarity, our reconstruction reveals a receptor interaction that is quite different from that observed for EV7. Fitting of the crystallographic co-ordinates for DAF34 and EV11 into the reconstruction shows a close agreement between the crystal structure of the receptor fragment and the density for the virus-bound receptor, allowing unambiguous positioning of the receptor with respect to the virion (PDB #1UPN). Our finding that the mode of virus-receptor interaction in EV12 is distinct from that seen for EV7 raises interesting questions regarding the evolution and biological significance of the DAF-binding phenotype in these viruses.
Resumo:
Decay-accelerating factor (CD55), a regulator of the alternative and classical pathways of complement activation, is expressed on all serum-exposed cells. It is used by pathogens, including many enteroviruses and uropathogenic Escherichia coli, as a receptor prior to infection. We describe the x-ray structure of a pathogen-binding fragment of human CD55 at 1.7 A resolution containing two of the three domains required for regulation of human complement. We have used mutagenesis to map biological functions onto the molecule; decay-accelerating activity maps to a single face of the molecule, whereas bacterial and viral pathogens recognize a variety of different sites on CD55.
Resumo:
The use of natural plant anthelmintics was suggested as a possible alternative control of gastrointestinal nematodes (GIN) in ruminants. Direct anthelmintic effects of tannin-containing plants have already been shown in sheep and goat GIN. These anthelmintic properties are mainly associated with condensed tannins. In the present study, we evaluated possible in vitro effects of three tannin-containing plants against bovine GIN. Effects of Onobrychis viciifolia, Lotus pedunculatus and Lotus corniculatus condensed tannin (CT) extracts on Cooperia oncophora and Ostertagia ostertagi were determined by a larval feeding inhibition assay (LFIA) and a larval exsheathment assay (LEA). In the LFIA, all three plant extracts significantly inhibited larval feeding behaviour of both C. oncophora and O. ostertagi first stage larvae in a dose-dependent manner. The L. pedunculatus extract, based on EC50 (effective concentration for 50% inhibition), was the most effective against both nematodes, followed by O. viciifolia and L. corniculatus. The effect of CT extracts upon larval feeding behaviour correlates with CT content and procyanidin/prodelphidin ratio. Larval exsheathment of C. oncophora and O. ostertagi L3 larvae (third stage larvae) was also affected by CT extracts from all three plants. In both in vitro assays, extracts with added polyvinylpolypyrrolidone, an inhibitor of tannins, generated almost the same values as the negative control; this confirms the role of CT in the anthelmintic effect of these plant extracts. Our results, therefore, indicated that tannin-containing plants could act against cattle nematodes.
Resumo:
We review the procedures and challenges that must be considered when using geoid data derived from the Gravity and steady-state Ocean Circulation Explorer (GOCE) mission in order to constrain the circulation and water mass representation in an ocean 5 general circulation model. It covers the combination of the geoid information with timemean sea level information derived from satellite altimeter data, to construct a mean dynamic topography (MDT), and considers how this complements the time-varying sea level anomaly, also available from the satellite altimeter. We particularly consider the compatibility of these different fields in their spatial scale content, their temporal rep10 resentation, and in their error covariances. These considerations are very important when the resulting data are to be used to estimate ocean circulation and its corresponding errors. We describe the further steps needed for assimilating the resulting dynamic topography information into an ocean circulation model using three different operational fore15 casting and data assimilation systems. We look at methods used for assimilating altimeter anomaly data in the absence of a suitable geoid, and then discuss different approaches which have been tried for assimilating the additional geoid information. We review the problems that have been encountered and the lessons learned in order the help future users. Finally we present some results from the use of GRACE geoid in20 formation in the operational oceanography community and discuss the future potential gains that may be obtained from a new GOCE geoid.
Resumo:
Background: Association mapping, initially developed in human disease genetics, is now being applied to plant species. The model species Arabidopsis provided some of the first examples of association mapping in plants, identifying previously cloned flowering time genes, despite high population sub-structure. More recently, association genetics has been applied to barley, where breeding activity has resulted in a high degree of population sub-structure. A major genotypic division within barley is that between winter- and spring-sown varieties, which differ in their requirement for vernalization to promote subsequent flowering. To date, all attempts to validate association genetics in barley by identifying major flowering time loci that control vernalization requirement (VRN-H1 and VRN-H2) have failed. Here, we validate the use of association genetics in barley by identifying VRN-H1 and VRN-H2, despite their prominent role in determining population sub-structure. Results: By taking barley as a typical inbreeding crop, and seasonal growth habit as a major partitioning phenotype, we develop an association mapping approach which successfully identifies VRN-H1 and VRN-H2, the underlying loci largely responsible for this agronomic division. We find a combination of Structured Association followed by Genomic Control to correct for population structure and inflation of the test statistic, resolved significant associations only with VRN-H1 and the VRN-H2 candidate genes, as well as two genes closely linked to VRN-H1 (HvCSFs1 and HvPHYC). Conclusion: We show that, after employing appropriate statistical methods to correct for population sub-structure, the genome-wide partitioning effect of allelic status at VRN-H1 and VRN-H2 does not result in the high levels of spurious association expected to occur in highly structured samples. Furthermore, we demonstrate that both VRN-H1 and the candidate VRN-H2 genes can be identified using association mapping. Discrimination between intragenic VRN-H1 markers was achieved, indicating that candidate causative polymorphisms may be discerned and prioritised within a larger set of positive associations. This proof of concept study demonstrates the feasibility of association mapping in barley, even within highly structured populations. A major advantage of this method is that it does not require large numbers of genome-wide markers, and is therefore suitable for fine mapping and candidate gene evaluation, especially in species for which large numbers of genetic markers are either unavailable or too costly.