HETEROTIC GROUP FORMATION IN PSIDIUM GUAJAVA L. BY ARTIFICIAL NEURAL NETWORK AND DISCRIMINANT ANALYSIS

ABSTRACT The present study aimed at evaluating the heterotic group formation in guava based on quantitative descriptors and using artificial neural network (ANN). For such, we evaluated eight quantitative descriptors. Large genetic variability was found for the eight quantitative traits in the 138 genotypes of guava. The artificial neural network technique determined that the optimal number of groups was three. The grouping consistency was determined by linear discriminant analysis, which obtained classification percentage of the groups, with a value of 86 %. It was concluded that the artificial neural network method is effective to detect genetic divergence and heterotic group formation.

Capturing diagnosis-timing in ICD-coded hospital data: recommendations from the WHO ICD-11 topic advisory group on quality and safety.

PURPOSE: To develop a consensus opinion regarding capturing diagnosis-timing in coded hospital data. METHODS: As part of the World Health Organization International Classification of Diseases-11th Revision initiative, the Quality and Safety Topic Advisory Group is charged with enhancing the capture of quality and patient safety information in morbidity data sets. One such feature is a diagnosis-timing flag. The Group has undertaken a narrative literature review, scanned national experiences focusing on countries currently using timing flags, and held a series of meetings to derive formal recommendations regarding diagnosis-timing reporting. RESULTS: The completeness of diagnosis-timing reporting continues to improve with experience and use; studies indicate that it enhances risk-adjustment and may have a substantial impact on hospital performance estimates, especially for conditions/procedures that involve acutely ill patients. However, studies suggest that its reliability varies, is better for surgical than medical patients (kappa in hip fracture patients of 0.7-1.0 versus kappa in pneumonia of 0.2-0.6) and is dependent on coder training and setting. It may allow simpler and more precise specification of quality indicators. CONCLUSIONS: As the evidence indicates that a diagnosis-timing flag improves the ability of routinely collected, coded hospital data to support outcomes research and the development of quality and safety indicators, the Group recommends that a classification of 'arising after admission' (yes/no), with permitted designations of 'unknown or clinically undetermined', will facilitate coding while providing flexibility when there is uncertainty. Clear coding standards and guidelines with ongoing coder education will be necessary to ensure reliability of the diagnosis-timing flag.

Cooperation versus competition effects on information sharing and use in group decision making

Information processing in groups has long been seen as a cooperative process. In contrast with this assumption, group members were rarely found to behave cooperatively: They withhold unshared information and stick to initial incorrect decisions. In the present article, we examined how group members' cooperative and competitivemotives impact on group information processing and propose that information sharing and use in groups could be seen as strategic behavior. We reviewed the latest developments in the literature investigating different forms of strategic information processing and their underlying mechanisms. This review suggests that explicit cooperative goals are needed for effective group decision-making.

Painopaperin valinta painotuotteen ostossa, case Kesko.

Tutkielman tarkoituksena on selvittää, miten yrityksen sisäiset ja ulkoiset vuorovaikutussuhteet vaikuttavat tuotteen ostoprosessissa. Sisäiset vuorovaikutussuhteet esiintyvät yrityksissä organisaatio-, ryhmä- ja individuaalisella tasolla. Nämä vaikuttavat lähinnä siihen, missä ja kenen toimesta ostopäätökset tehdään. Ulkoisia vuorovaikutussuhteita yrityksillä on usein esimerkiksi myyjään, toimitusketjun väliportaaseen ja yrityksen omaan asiakkaaseen. Nämä vuorovaikutussuhteet voivat vaikuttaa ostovalintoihin joko suoraan tai välillisesti. Tutkimusmenetelmänä on soveltava case-tutkimus, johon case-yritykseksi on valittu Kesko. Tavoitteena on selvittää ensinnäkin, mitä erilaisia sisäisiä ja ulkoisia vuorovaikutussuhteita Keskon painotuotteen ostoprosessissa esiintyy, ja toiseksi, miten nämä vuorovaikutussuhteet vaikuttavat Keskon painopaperin valintaan. Tutkimuksen tarkoituksena on tukea markkinointistrategian suunnittelua UPM-Kymmenen kotimaan myyntiosastolla antamalla kuva painopaperimarkkinoiden rakenteesta ja Keskon painopaperin valinnan muodostumisesta.

Balanced Scorecard -mittaristo strategisena ohjaustyökaluna konserniympäristössä. Case: Stora Enso Packaging Oy

Tässä pro gradu -tutkielmassa analysoidaan neljästä eri näkökulmasta koostuvan Balanced Scorecardin soveltamista strategisena ohjaustyökaluna. Tavoitteena on Balanced Scorecardin toteuttamiseen liittyvän strategisen päätöksenteon tukeminen. Teoriaosuus on toteutettu kirjallisuuden pohjalta ja empiirinen aineisto on koottu lähinnä case-yrityksen omasta Balanced Scorecard -projektista. Case-yritys on maailmanlaajuisem Stora Enso -konsernin täysin omistama täyden palvelun aaltopahviratkaisuihin erikoistunut tytäryhtiökonserni. Balanced Scorecard -projekti yrityksessä on ollu käynnissä jo parin vuoden ajan ja nykyään käytössä on myös atk-pohjainen Balanced Scorecard -ohjelmisto. Tulevaisuudessa tavoitteena on Balanced Scorecardin ja siihen liityvän ohjelmiston ottaminen käyttöön koko konsernin kaikilla organisaatiotasoilla. Tutkimuksen tuloksena mallin todetaan teorian lisäksi myös käytännössä kokoavan hajanaiset tiedot tiiviiksi ja johdonmukaiseksi kokonaisuudeksi. Balanced Scorecardin onnistuminen riippuu paljolti työntekijöiden sitoutumisesta ja johdon halusta aikaansaada muutoksia. Oikein sovellettuna Balanced Scorecard on tehokas kommunikointiväline, joka kehittyy jatkuvasti organisaation mukana. Suurimpana ongelmana tai haasteena Suomessa nähdään mallin sisäistäminen alemmilla organisaatiotasoilla. Tutkimuksessa tarjotaan tähän ratkaisuksi uuden suomenkielisen käsitteen lanseeraamista ja parempaa tiedottamista esimerkiksi intranetin välityksellä.

ASP-malli ja sen alustavien kohdesegmenttien määrittely. Case: Novo Group Oyj

Tutkielman tavoitteena oli selvittää ASP-, eli sovellusvuokrausmallin erityis-piirteitä sekä määrittää alustavat kohdesegmentit toiminnan-, talouden- ja henkilöstönohjausjärjestelmille ASP-ratkaisuna. Työ on kaksiosainen. Tutkimuksen teoreettisessa osassa keskitytään segmentoinnin teorioihin, tietojärjestelmien ulkoistamisen motiiveihin sekä etuihin ja haittoihin sekä ASP-malliin kokonaisuudessaan. Tutkimuksen empiiristä osuutta varten suoritettiin kvalitatiivinen tutkimus, joka koostui 20 haastattelusta 18 eri organisaatiossa. Haastateltavat olivat pääasiassa asiakasyritysten tietohallintopäällikköjä. Alustavat kohdesegmentit muodostettiin teoreettisessa osassa esitettyjen ASP-mallin erityispiirteiden sekä haastattelututkimuksesta saadun informaation perusteella. ASP on uusi malli tietojärjestelmien hankintaan. ASP on käsitteenä vain noin kolme vuotta vanha tutkielman tekohetkellä. Kyseessä on malli, jolle tutkimuslaitokset ovat tehneet lupaavia kasvuennusteita IT-markkinoilla. Markkinoiden kasvu ei ole kuitenkaan ollut ennusteiden mukaista. ASP-ratkaisuna hankittu tietojärjestelmä on kokonaisvaltainen ulkoistusmalli. Kaikki mahdollinen ASP-ratkaisuna hankittavaan järjestelmään tai sovellukseen liittyvä ulkoistetaan palveluntarjoajalle. Tutkimuksessa selvisi, että kiinnostusta mallia kohtaan on olemassa. Mallin edut nähdään suurempina kuin haitat. ASP-ratkaisun käyttöönotolla asiakasyritykselle mahdollistuu resurssien kohdentaminen ydinliiketoimintaan.

Establishing the Stages and Processes of Change for Weight Loss by Consensus of Experts

The present study aimed to establish, by a consensus of experts, the stages and processes of change for weight management in overweight and obese people. The first step involved developing two questionnaires aimed at assessing stages and processes of change for weight loss in overweight and obese people. The processes-ofchange questionnaire consisted of 12 subscales, and contained 107 items. A three-round Delphi study was carried out through a website, where participants were asked to give their opinion about the representativeness and clarity of the scale items. The stages-of-change questionnaire consisted of five items and was presented in the final round of the study. A team of 66 experts in the obesity field from 29 countries participated in the study. They were selected either because they belonged to the organizing committee of international associations related to obesity, or because of their research career. The required changes in the questionnaire were made according to the opinions of the participants. Some of these were the result of the group statistical response, whereas others were due to the suggestions made by the participants. A final version of the questionnaire consisting of 63 items was eventually obtained. The present study produced two questionnaires to assess stages and processes of change for weight management. The strength of the study lies in the consensus reached by the panel of experts in order to establish the required content of the questionnaires. The two measures provide useful tools for practitioners who wish to tailor weight-management interventions according to transtheoretical model constructs.

Planarian (Platyhelminthes, Tricladida) Diversity and Molecular Markers: A New View of an Old Group

Planarians are a group of free-living platyhelminths (triclads) best-known largely due to long-standing regeneration and pattern formation research. However, the group"s diversity and evolutionary history has been mostly overlooked. A few taxonomists have focused on certain groups, resulting in the description of many species and the establishment of higher-level groups within the Tricladida. However, the scarcity of morphological features precludes inference of phylogenetic relationships among these taxa. The incorporation of molecular markers to study their diversity and phylogenetic relationships has facilitated disentangling many conundrums related to planarians and even allowed their use as phylogeographic model organisms. Here, we present some case examples ranging from delimiting species in an integrative style, and barcoding them, to analysing their evolutionary history on a lower scale to infer processes affecting biodiversity origin, or on a higher scale to understand the genus level or even higher relationships. In many cases, these studies have allowed proposing better classifications and resulted in taxonomical changes. We also explain shortcomings resulting in a lack of resolution or power to apply the most up-to-date data analyses. Next-generation sequencing methodologies may help improve this situation and accelerate their use as model organisms.

Developing a theoretical framework using a nursing perspective to investigate perceived health in the "Sandwich Generation" group

Coexisting workloads from professional, household and family, and caregiving activities for frail parents expose middle-aged individuals, the so-called "Sandwich Generation", to potential health risks. Current trends suggest that this situation will continue or increase. Thus SG health promotion has become a nursing concern. Most existing research considers coexisting workloads a priori pathogenic. Most studies have examined the association of one, versus two, of these three activities with health. Few studies have used a nursing perspective. This article presents the development of a framework based on a nursing model. We integrated Siegrist's Effort-Reward Imbalance middle-range theory into "Neuman Systems Model". The latter was chosen for its salutogenic orientation, its attention to preventive nursing interventions and the opportunity it provides to simultaneously consider positive and negative perceptions of SG health and SG coexisting workloads. Finally, it facilitated a theoretical identification of health protective factors.

Epidemiology and outcome of fungemia in a cancer Cohort of the Infectious Diseases Group (IDG) of the European Organization for Research and Treatment of Cancer (EORTC 65031).

BACKGROUND: Anti-cancer treatment and the cancer population have evolved since the last European Organisation for Research and Treatment of Cancer (EORTC) fungemia survey, and there are few recent large epidemiological studies. METHODS: This was a prospective cohort study including 145 030 admissions of patients with cancer from 13 EORTC centers. Incidence, clinical characteristics, and outcome of fungemia were analyzed. RESULTS: Fungemia occurred in 333 (0.23%; 95% confidence interval [CI], .21-.26) patients, ranging from 0.15% in patients with solid tumors to 1.55% in hematopoietic stem cell transplantation recipients. In 297 evaluable patients age ranged from 17 to 88 years (median 56 years), 144 (48%) patients were female, 165 (56%) had solid tumors, and 140 (47%) had hematological malignancies. Fungemia including polymicrobial infection was due to: Candida spp. in 267 (90%), C. albicans in 128 (48%), and other Candida spp. in 145 (54%) patients. Favorable overall response was achieved in 113 (46.5%) patients by week 2. After 4 weeks, the survival rate was 64% (95% CI, 59%-70%) and was not significantly different between Candida spp. Multivariable logistic regression identified baseline septic shock (odds ratio [OR] 3.04, 95% CI, 1.22-7.58) and tachypnoea as poor prognostic factors (OR 2.95, 95% CI, 1.66-5.24), while antifungal prophylaxis prior to fungemia (OR 0.20, 95% CI, .06-.62) and remission of underlying cancer (OR, 0.18; 95% CI, .06-.50) were protective. CONCLUSIONS: Fungemia, mostly due to Candida spp., was rare in cancer patients from EORTC centers but was associated with substantial mortality. Antifungal prophylaxis and remission of cancer predicted better survival.