Development of new analytical tools for monitoring of cardiovascular disease markers – towards the detection of homocysteine-thiolactone

Poster presented at the 4th International Conference on Bio-Sensing Technology, 10-13 May 2015, Lisbon, Portugal

Lichtheimia Infection in a Lymphoma Patient: Case Report and a Brief Review of the Available Diagnostic Tools

We describe the case of a patient with a T-lymphoblastic lymphoma whose disseminated mucormycosis was diagnosed with delay, and we address the diagnostic and therapeutic decision-making process and review the diagnostic workup of patients with potential IFD. The diagnosis was delayed despite a suggestive radiological presentation of the patient's pulmonary lesion. The uncommon risk profile (T-lymphoblastic lymphoma, short neutropenic phases) wrongly led to a low level of suspicion. The diagnosis was also hampered by the lack of indirect markers for infections caused by Mucorales, the low sensitivity of both fungal culture and panfungal PCR, and the limited availability of species-specific PCR. A high level of suspicion of IFD is needed, and aggressive diagnostic procedures should be promptly initiated even in apparently low-risk patients with uncommon presentations. The extent of the analytical workup should be decided on a case-by-case base. Diagnostic tests such as the galactomannan and β-D-glucan test and/or PCR on biological material followed by sequencing should be chosen according to their availability and after evaluation of their specificity and sensitivity. In high-risk patients, preemptive therapy with a broad-spectrum mould-active antifungal agent should be started before definitive diagnostic findings become available.

Towards moldable development tools

Developers commonly ask detailed and domain-specific questions about the software systems they are developing and maintaining. Integrated development environments (IDEs) form an essential category of tools for developing software that should support software engineering decision making. Unfortunately, rigid and generic IDEs that focus on low-level programming tasks, that promote code rather than data, and that suppress customization, offer limited support for informed decision making during software development. We propose to improve decision making within IDEs by moving from generic to context-aware IDEs through moldable tools. In this paper, we promote the idea of moldable tools, illustrate it with concrete examples, and discuss future research directions.

Chronological clinical and pathological documentation of porcine ulcerative dermatitis

BACKGROUND: Porcine ulcerative dermatitis syndrome (PUDS) is a rare disease of breeding sows with an unknown pathogenesis. OBJECTIVE: To describe the evolution of clinical and histopathological lesions over the course of the disease and to elucidate the pathogenesis. ANIMAL: A 24-month-old, pluriparous, large white sow presented during gestation with ulcerations around the teats compatible with PUDS. METHODS AND RESULTS: Clinical and histopathological lesions were monitored over the course of the disease (i.e. during and after the subsequent pregnancy). A clear gestation-dependent flare of the lesions was observed with partial resolution occurring postpartum. The histological pattern presented as a lymphocytic interface dermatitis. CONCLUSIONS AND CLINICAL IMPORTANCE: The findings in this case report link gestation with the development of clinical signs and histological changes. Multiparity appears to enhance severity and may finally result in a self-perpetuating disease. Therefore, it seems advisable to cull breeding sows after they have developed PUDS.

Tools for compliance for the medical device and in vitrol diagnostic product industries.

Mode of access: Internet.

Final report -- a survey of software tools usage /

S/N 003-003-02378-7

The Holy Bible, containing the authorized and revised versions of the Old and New Testaments, arranged in parallel columns. The text conformable to that of the Universities of Oxford and Cambridge. With a complete concordance and the Psalms of David in metre. Copious marginal references, chronological tables, and many important and useful aids to the study of the Holy scriptures ...

Mode of access: Internet.

Schedule of two thousand American historical nuggets taken : from the Stevens diggings in September 1870 and set down in chronological order of printing from 1490 to 1800 [i.e. 1776] ; described and recommended as a supplement to any printed Bibliotheca Americana /

A list of about 1400 titles not found in John Carter Brown's Bibliotheca Americana.

Hand and power tools : a compilation /

At head of title: Technology utilization.

Machinery, equipment, and tools : a compilation.

Cover title.

Tools for embedded computing systems software.

"Preprint for a workshop sponsored by NASA Langley Research Center, Hampton, Virginia, and the American Institute of Aeronautics and Astronautics, New York, and held in Hampton, Virginia, November 7-8, 1978."

The elements of Roman law summarized : a concise digest of the matter contained in the Institutes of Gaius and Justinian with copious references arranged in parallel columns, also chronological and analytical tables, lists of laws, etc., etc. : primarily designed for the use of students preparing for examination at Oxford, Cambridge, and the Inns of Court /

Includes index.

Identifying and implementing corridor safety improvements: a highway safety improvement process and safety analysis tools for Arizona.

Arizona Department of Transportation, Phoenix

Support for the analytical tools for automotive fuel economy activities. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Prevention plus II : tools for creating and sustaining drug-free communities.

Mode of access: Internet.