Letter from Nathan Prince to Edward Holyoke, Feb. 22, 1741/2

In this letter, Prince informs Holyoke of his desire to appeal the Board of Overseers' decision to dismiss him. Prince also asserts his belief that, until his appeal is considered, he should continue to perform his duties as Tutor and that the Corporation has no legal authority to fill a vacancy which does not exist.

Letter from Nathan Prince to Edward Holyoke, June 24, 1742

In this letter, Prince questions the legality of his dismissal.

John Lovell and Jeremiah Allen's statement regarding their visit to Nathan Prince, accompanying Edward Holyoke, July 12, 1742

Lovell and Allen accompanied Holyoke to Nathan Prince's lodging in Boston, to personally inform him that the Board of Overseers had voted for his dismissal and that his belongings had been removed from his chamber and were being stored in town until he chose to claim them.

Nathan Prince's pledge of indemnity towards Henry Prentice and Mary Prentice, ca. 1742

Although the context of this document is not entirely clear, it appears that the Prentices were responsible for storing Prince's belongings – recently removed from his Harvard chamber – until he could claim them. These included his "wearing linnen," "wearing cloathe & five or six papers," and "five or six books."

Paper wrapper formerly used to bundle records related to Nathan Prince, undated

Recto of wrapper reads: "Oct. 31, 1740 to June 24, 1742. Papers relative to the charges against & defence made by Nathan Prince in 1741. Examined & done with." Verso reads "Hon. President [Josiah] Quincy." These annotations suggest that the records in this collection were consulted by Quincy, who served as Harvard's President from 1829 to 1845. It is likely that he used them when writing his two-volume History of Harvard University, which includes a lengthy passage about Prince and his trials at Harvard.

Letter of recommendation for Amos Main from Joseph Moodey to Nathan Prince, 1725 July 2

Handwritten letter sent by Joseph Moody, schoolmaster in York, to Harvard Tutor Nathan Prince recommending student Amos Main for acceptance to the College. In the letter, Moody requests Prince give Main an examination for admission, with the caveat that though Main has been studying Latin and Greek he has a difficult home life and is "somewhat Raw; yet I hope you'l wink at it." The letter, dated July 2, 1725, is written on a folded folio-sized leaf; there are handwritten notes about Massachusetts towns on the verso.

Student notebook of Thomas Prince, ca. 1707

Paper notebook in Latin on classical Greek grammar. The name "Thomas Prince" appears on the first page. The manuscript is undated. Based on the signature, this volume is assumed to have belonged to Thomas Prince, Sr., although it is undated and may have indeed belonged to Thomas Prince, Jr.

Aplicação de técnicas de detecção de apoptose versus proliferação celular no estudo do mastocitoma canino

A apoptose é um mecanismo de morte celular programada que ocorre naturalmente nos tecidos. Alterações neste mecanismo podem resultar na formação de neoplasias. O mastocitoma é uma das neoplasias cutâneas mais frequente em canídeos. O fator de prognóstico mais utilizado é o grau histológico. Porém, devido à imprevisibilidade desta neoplasia é necessário um melhor conhecimento do comportamento da mesma para se melhorarem competências em oncologia. Neste projeto foram estudados 23 amostras de mastocitomas caninos de variadas idades, raça e sexo, que foram submetidas à técnica de imunohistoquímica de modo a analisar a expressão de dois marcadores pró-apoptóticos (TUNEL e Bax), um marcador antiapoptótico (Bcl-2) e um marcador proliferativo (Ki-67). A expressão de TUNEL, Bcl-2 e Ki-67 aumentou do grau I para o grau III do mastocitoma e a de Bax diminuiu. Houve também uma diminuição na expressão de Bax e Bcl-2 no mastocitomas de grau II e um ligeiro aumento na expressão de Ki-67 na mesma classe tumoral. Observou-se assim maior atividade anti-apoptótica e aumento da proliferação celular, associados a um ao prolongamento na sobrevivência das células neoplásicas e, consequentemente, a um pior prognóstico, no grau de malignidade mais severo o grau III.