901 resultados para Biotecnologia animal


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Zootecnia - FCAV

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Chronic obstructive pulmonary disease (COPD) is characterized by progressive airway obstruction resultant from an augmented inflammatory response of the respiratory tract to noxious particles and gases. Previous reports present a number of different hypotheses about the etiology and pathophysiology of COPD. The generating mechanisms of the disease are subject of much speculation, and a series of questions and controversies among experts still remain. In this context, several experimental models have been proposed in order to broaden the knowledge on the pathophysiological characteristics of the disease, as well as the search for new therapeutic approaches for acute or chronically injured lung tissue. This review aims to present the main experimental models of COPD, more specifically emphysema, as well as to describe the main characteristics, advantages, disadvantages, possibilities of application, and potential contribution of each of these models for the knowledge on the pathophysiological aspects and to test new treatment options for obstructive lung diseases.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The traffic of wild animals can be identified as the main cause of finding captive animals in zoos and sorting centers in Brazil. The maintenance of these animals in captivity is usually justified by the prevention of total loss of individuals of that specie, if it becomes extinct in the wild, and also, the importance of these subjects in studies of basic biology of the species. Keeping animals in captivity environment brings the need to ensure the welfare of them. The high population density and limited space are some of the possible stressors that these individuals face in capivity. Even the low pressure feeding and food easily available could be stressors, since they change the budget activities typical of the specie, causing sedentary behavior and sometimes depression. The captive environment and activities related to it (handling, transport, social change and social isolation) could compromise the animal welfare. Reduction in life expectancy, impaired growth and reproduction, personal injury, illness, immunosuppression, exacerbated adrenal activity and abnormal behavior, are events often lonked to compromised welfare. Hence, assessment and promoter methods are used to provide the welfare to captive animals. The assessment can be made by hormonal and/or behavioral measures. Both are extremely important, and usually are used in combination, to provide more tangible results about the condition of the animal. The promotion of animal welfare can be accomplished through environmental enrichment, a technique which aims to provide a more complex and diverse environment, increasing the possibility of the animal express more natural behavior, or characteristic of the species. Thus, the objective of this dissertation is discuss the importance of animal welfare and the ways this can be evaluated and promoted... (Complete abstract click electronic access below)

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The relationship between humans and the world around is getting less symbiotic and harmonic, so as with the other animals we share the planet with, mostly about domination of plagues, domination for food, company, work or fun. This last both are responsible for the beginning of the Circus as we know, with the exhibition of wild animals and horses, and have been increased with clowns, acrobats, and jugglers, street artists, getting to be one unified show all around the world, which most of them don´t have animals. Following this tendency, the PL 7291/06 is on process on the plenary assembly to forbidden the animals inside Circus. In that matter, this work is a Phenomenological perspective of the phenomenon Circus’s animals sited beyond the animal rights activists perspective. The Ideographic and Nomotetic analysis of the activist’s speech realize that is no discordance between then. All the speeches agrees that the animal must be out of the circus, and most of them agrees about the cruelty involving the animal´s domination, about that ONGs should be the better destination for this animals, and they shows lack of knowledge about the Brazilian Circus, with or without animals, their traditions and characteristics, so as the lack of knowledge about de ecology and biology of the animals involved.

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A experimentação em animais é a metodologia mais utilizada para se testar a ação de todo tipo de droga em um organismo e suas reações. Atualmente existe na ciência a preocupação com a ética para amenizar o sofrimento dos animais envolvidos. Com o advento de novas tecnologias, são propostas técnicas alternativas que se abstém da utilização destes. Mas que não são ainda largamente estudadas no Brasil. Portanto realizou-se uma breve revisão das relações ser - humano/natureza presentes historicamente na atividade científica. Foram respondidos questionários e entregues para a análise, no qual se teve o objetivo de averiguar a opinião em relação a esse assunto perante os experimentadores de um conceituado Centro de Pesquisas e verificar assim, a possibilidade da inserção de uma nova ética, a qual possa futuramente livrar todos os animais de qualquer sofrimento. Os pesquisadores apresentam de uma forma geral, uma pequena preocupação com a reflexão sobre a utilização de materiais alternativos, em contrapartida se mostram bastante preocupados com a utilização dos animais de forma ética, a fim de minimizarem o sofrimento causado

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Considerando os conceitos de senciência e bem-estar animal, os testes de escolha e preferência são das alternativas interessantes para se discutir o bem-estar em peixes. Assim, avaliamos a escolha da tilápia-do-Nilo (Oreochromis niloticus) em manter-se em isolamento ou próxima a coespecíficos não-familiares de diferentes tamanhos (menores, similares ou maiores que o peixe-foco). O tamanho foi estudado por ser um fator determinante da dominância. Admitindo que o grau de atenção dos indivíduos possa ter flutuação circadiana, testamos também se o período do dia (manhã e tarde) afeta essa escolha. A escolha foi determinada pela maior freqüência do animal junto ao respectivo estímulo. Nesse estudo vimos que a tilápia-do-Nilo apresenta dois perfis de escolha: “decididos”, onde os animais escolhem uma posição em número significativamente maior de vezes; e os “indecisos”, que escolhem igualmente no mínimo duas opções de estímulos. No período da manhã há maior proporção de animais “decididos” do que à tarde. Portanto, embora não tenhamos detectado uma nítida escolha por tamanho de coespecífico o período do dia influenciou o número de indivíduos em cada um dos perfis. Assim, concluímos que a tomada de decisão na tilápia-do-Nilo varia em função do período do dia

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The beneficial effects derived from the nutritional support in human patients and experimental animal models include the improvement of immune function, repair of wounds, answer to the treatment, time of recovery and survival. In front of these benefits, we end up alienating the nutritional needs of hospitalized patients, especially those with clinical or surgical affections threatening. The objective of the nutritional support is to indicate the importancea and the proportions of energy and nutrients that the patient can use with the maximum effectiveness. The majority of hospitalized patients do not have voluntary food intake adequate to meet even the minimal nutritional needs. It is often perceived that lack of adequate food intake, will have serious impact on the patient’s clinical outcome. The nutritional assessment will help determine which route of feeding will be the safest, most effective and best tolerated by the patient. Diet choice is based on which of the patient’s problems can and should be addressed with nutrition and the feeding access available

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Physics governs all working patterns of the universe and could not be otherwise in a biological environment. Living things depend directly on laws and physical models to compose their body structure, allow its survival in certain environments, communication between individuals and groups and also to establish a complex sensorial system that allows interaction with the environment that surrounds them. With the advancement of science and technology, new ideas are required, and thus, many researchers began to turn their attention to those systems found in nature, as these systems often present practical solutions and with maximum efficiency. This imitation of biological systems, applied in creating innovative technological resources, is called Biomimetics. To study the biological systems based on physical concepts is essential the creation of models. These allow the distinction of the effects of the issue really essential and may be ignored side effects that do not have an effective participation in the phenomenon being analyzed. In this Work Completion of course will be studied the phenomenon of countercurrent heat exchangers, present in various situations of nature, focusing on their participation in the legs of birds, also the balance of certain birds that are supported on one leg and possible inspiration of these phenomena in the fields of engineering. Also included are videos that allow better understanding of the studied subjects

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Nos últimos 40 anos, a biotecnologia tem evoluído significativamente, gerando uma série de repercussões e possibilidades para diversos setores. Embora os avanços tenham impactos muito amplos, um dos setores que mais se beneficiam do desenvolvimento da biotecnologia é a agricultura. Em meio a um contexto favorável para o desenvolvimento da biotecnologia no Brasil, buscaremos analisar o papel do setor público, de instituições de pesquisa e ensino e de empresas nacionais e transnacionais, bem como o estímulo à cooperação entre universidades e empresas do setor de defensivos agrícolas e sementes

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The gastrointestinal tract is the main route of nutrients absorption and drugs delivery. Is important to know the parameters related to the tract, like gastric emptying and gastrointestinal transit, in order to better understand the behavior of different kind of meals or drugs passing through the GIT. Many techniques are used to study these parameters, such as manometry, scintigraphy, phenol red, activated charcoal and carbon-13 reading. However, these methods use radiation, are invasive and require animal sacrifice. As an alternative proposal, the Alternate Current Biosusceptometry (ACB), a magnetic technique, has proved to be effective for these studies with small animals, in a noninvasive way, low cost, radiation free and avoiding the animal death. Associating the ACB to magnetic micro or nanoparticles used as tracers, it is possible to observe the meal behavior inside of the GIT. Focusing meanly on liquid meals digestion, this paper had the objective to evaluate the efficiency of the ACB technique in gastric emptying and gastrointestinal transit evaluation of liquid meals in rats. To perform the experiments, magnetic nanoparticles (ferrite, MgFe2O4) were used on a 1,5 ml solution introduced by gavage on similar weight and age rats. The sensor made by 2 pairs of coils, capable of generating and detecting magnetic fields, creates a field on the interest place and when this field is in contact with the marked meal, it changes, resulting on a variation of the measured voltage. The voltage variation is analyzed and is obtained a particle concentration on the interest region. The results showed that is possible to apply the ACB technique on the GIT evaluation of liquid particles digestion, gastric emptying and meal cecum arrival time curves were obtained and from that, is possible to observe a pattern of gastrointestinal transit. Both mean process time values were acquired, proving the technique capability of ...

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The theme of this project is the animal world, focusing on Bauru. The magazine Bauru Animal was born from the lack of publications addressing the issue of animals under the focus of their rights in this county. The treatment we give to animals is an important ethical and moral issue that should be discussed by the press. In Bauru there is an animal protection movement, whether organized or independent people. And there are many problems about the animals. The intent of the magazine is to report the status of animals in the city, checking legislation and getting into the philosophical field: we have the right to treat animals as mere environmental and economic resource? For the preparation of the materials were performed several interviews, documented in audio files and performed with the authors' theoretical Cremilda Medina and José Carlos Sebe Bom Meihy. The animal issue is cross-cutting issue that involves all traditional media editorials and allows public bodies to discuss assignments, ethical, moral and legal, the role of the citizen in society and many other issues relevant to the media