Stone, Sam, 1602-1663, autographed letter signed to John Winthrop; Hartford, 1 side (3 pages), 1652 February 1652

Correspondence seeking advice from Winthrop about his 23-week-old son, who was suffering from jaundice and a cough. Stone writes the course of treatment for the infant, on the advice of a Mrs. Hooker, had included barbaric bark boiled in beer with saffron twice daily, as well as turmeric. He also administered Winthrop's purging powder, and Stone asks if he should continue giving the powder and at what dose, and if there is any other medicines Winthrop would prescribe.

Bering Sea and Arctic Ocean Region, 1882 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Behring's Sea and Arctic Ocean : from surveys of the U.S. North Pacific Surveying Expedition in 1855, Commander John Rodgers U.S.N. commanding and from Russian and English authorities, J.C.P. de Kraft, commodore U.S.N. Hydrographer to the Bureau of Navigation ; compiled by E.R. Knorr ; drawn by Louis Waldecker. Corr. & additions to Jan. 1882. It was published by U.S. Navy, Hydrographic Office in 1882. Scale [ca. 1:4,400,000]. Covers the Bering Sea and Arctic Ocean region. The image inside the map neatline is georeferenced to the surface of the earth and fit to a non-standard 'Mercator' projection with the central meridian at 180 degrees west. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. Note: The central meridian of this map is not the same as the Prime Meridian and may wrap the International Date Line or overlap itself when displayed in GIS software. This map shows features such as drainage, cities and other human settlements, territorial boundaries, expedition routes, shoreline features, bays, harbors, islands, rocks, and more. Relief shown by hachures and spot heights. Depths shown by soundings. Includes drawing of Wrangel Island "as seen from Bark Nile of New London ... ; 15 to 18 miles distant". This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection and the Harvard University Library as part of the Open Collections Program at Harvard University project: Organizing Our World: Sponsored Exploration and Scientific Discovery in the Modern Age. Maps selected for the project correspond to various expeditions and represent a range of regions, originators, ground condition dates, scales, and purposes.

Novel antennal lobe substructures revealed in the small hive beetle Aethina tumida

The small hive beetle, Aethina tumida, is an emerging pest of social bee colonies. A. tumida shows a specialized life style for which olfaction seems to play a crucial role. To better understand the olfactory system of the beetle, we used immunohistochemistry and 3-D reconstruction to analyze brain structures, especially the paired antennal lobes (AL), which represent the first integration centers for odor information in the insect brain. The basic neuroarchitecture of the A. tumida brain compares well to the typical beetle and insect brain. In comparison to other insects, the AL are relatively large in relationship to other brain areas, suggesting that olfaction is of major importance for the beetle. The AL of both sexes contain about 70 olfactory glomeruli with no obvious size differences of the glomeruli between sexes. Similar to all other insects including beetles, immunostaining with an antiserum against serotonin revealed a large cell that projects from one AL to the contralateral AL to densely innervate all glomeruli. Immunostaining with an antiserum against tachykinin-related peptides (TKRP) revealed hitherto unknown structures in the AL. Small TKRP-immunoreactive spherical substructures are in both sexes evenly distributed within all glomeruli. The source for these immunoreactive islets is very likely a group of about 80 local AL interneurons. We offer two hypotheses on the function of such structures.

Indian Camp

on verso: No. 84. Indian Camp. Birch bark canoes on bank of Kaministiquia River, Canada.

Jottings from a cruise /

"Junior jottings from a cruse, by Allan A Green": p. [273]-451.

American medicinal barks /

"Issued June 5, 1909."

Dermatea carnea; Dermateaceae

Dermatea carnea Cooke & Ellis

Nectria aureofulva; Hypocreaceae

Nectria aureofulva Cooke & Ellis

Nectria truncata; Hypocreaceae

Nectria truncata Ellis

Mytilinidion juniperi; Hysteriaceae

Mytilinidion juniperi Ellis & Everh.

Valsa viburni; Diaporthaceae

Valsa viburni Fuckel, determined by L. Fuckel