R2D2 : a Fortran program for two-dimensional chemically reacting, hyperthermal, internal flows.

"January 1980."

Employment and pay rolls in state unemployment compensation systems, 1938. Employment security memorandum no. 6. pt. 1-2.

Pt. 1. Introduction and charts. Pt. 2. Tables.

Feasibility investigation of a moving belt raditor; summary report. Technical documentary report no. ASD-TDR-63-551. Aeronautical Systems Division, Wright-Patterson Air Force Base, Ohio. BPSN 2-(3-3145)-60853. Prepared under Contract no. AF33(657)-8127.

Photocopy.

Health information systems [microform] : hearings before the Subcommittee on Science, Research, and Technology and the Subcommittee on Natural Resources, Agriculture Research, and Environment of the Committee on Science and Technology, U.S. House of Representatives, Ninety-seventh Congress, first session, June 2, 3, 4, July 23, 1981.

"No. 54."

Organizational maintenance manual (including repair parts and special tools lists) : 2.75-inch low spin, folding fin aircraft rockets, 66-mm light antitank weapon systems, 3.5-inch rockets, and M3A2E1 rocket motor (JATO).

"June 1973."

Direct support and general support maintenance manual (including repair parts and special tools list) for 2.75-inch low spin, folding fin aircraft rockets, 66-mm light antitank weapon systems, 3.5-inch rockets and M3A2E1 rocket motor (JATO).

"August 1974."

Organizational maintenance manual (including repair parts and special tools lists) : 2.75-inch low spin, folding fin aircraft rockets, 66-mm light antitank weapon systems, 3.5-inch rockets, and M3A2E1 rocket motor (JATO).

"June 1973."

Operator's manual : platoon early warning systems AN/TRS-2(V)1 (NSN 5895-01-063-8103) ... AN/TRS-2(V)6 (NSN 5895-01-068-6749).

"30 June 1980."

Hearing to review the U.S. Department of Agriculture's release of program beneficiaries' social security numbers and the department's information systems, generally : hearing before the Committee on Agriculture, House of Representatives, One Hundred Tenth Congress, first session, May 2, 2007.

Shipping list no.: 2009-0305-P.

Piloted flight simulation study of low-level wind shear : phase 2 : all weather landing systems, engineering services support project, task 2 /

Includes bibliographical references.

Lipid, sugar and liposaccharide based delivery systems 2

The vast majority of biologically active compounds will never be considered as potential drugs due to inherently poor bioavailability. This review discusses the progress in the development of chemical systems to improve the metabolic stability, absorption and physicochemical properties of potential drugs. Delivery systems that involve the conjugation of lipid and/or sugar moieties are highlighted, as well as novel methods of conjugation of these groups to drugs. The use of sugar molecules to target drugs to particular organs or cells is also discussed, as is the use of lipids in the growing area of gene delivery. This is an update of a previous review [1].

NMR imaging of the diffusion of water at 37 degrees C into poly(2-hydroxyethyl methacrylate) containing aspirin or vitamin B-12

The ingress of water into poly(2-hydroxyethyl methacrylate), PHEMA, loaded with either one of two model drugs, vitamin B-12 or aspirin, was studied at 37 degreesC using three-dimensional NMR imaging. PHEMA was loaded with 5 and 10 wt % of the drugs. From the imaging profiles, it was observed that incorporation of vitamin B-12 into PHEMA resulted in enhanced crack formation on sorption of water and the crack healing behind the diffusion front was slower than for PHEMA without added drug. This was accounted for by the anti-plasticization of PHEMA by vitamin B-12. Crack formation was inhibited in the P-HEMA-aspirin systems because of the plasticizing effect of the aspirin on the PHEMA matrix. All of the polymers were found to absorb water according to an underlying Fickian diffusion mechanism. For PHEMA loaded with 5 wt % of aspirin or vitamin B-12, the best values of the water diffusion coefficients were both found to be 1.3 +/- 0.1 x 10(-11) m(2) s(-1) at 37 degreesC, while the values for the polymer loaded with 10 wt % of the drugs were slightly higher, 1.5 +/- 0.1 x 10(-11) m(2) s(-1).

Macrocyclic systems containing 2,6,9-trioxabicyclo[3.3.1]-nona-3,7-dienes as chiral spacer groups: Synthesis, stereochemical features and preliminary complexation properties

Novel 2:2-macrocycles bearing bridged concave 2,6,9-trioxabicyclo[3.3.1]nona-3,7-dienes as chiral spacer units were obtained by cyclocondensation reaction of the chiral bisacid chloride and the corresponding diols, while use of methylene diamines instead of diols afforded 1:1 macrocycles only. Applying the same, but now template-assisted, experimental procedure to the reaction of the bisacid chloride with triethylene glycol brought about a significant increase in yield as well as a suitable simplification of the work-up during preparation and separation of the corresponding 1:1 as well as 2:2 macrocycles, when compared to results reported previously. HPLC separation on chiral columns revealed the presence of diastereoisomers [RR(S,S)- and RS-(meso)-forms] for all 2:2 macrocycles, which was further evidenced by the CD spectrum of one of those species as an example. Preliminary ESI-MS experiments indicated strong complexation abilities of the sulphur-containing ligand towards Ag(I), Cu(II) and Au(III) ions.