Trajetórias educacionais de estudantes de curso de pós-graduação da UNIFRAN na modalidade a distância

Pós-graduação em Educação Escolar - FCLAR

A Ética na Experimentação Animal

A experimentação em animais é a metodologia mais utilizada para se testar a ação de todo tipo de droga em um organismo e suas reações. Atualmente existe na ciência a preocupação com a ética para amenizar o sofrimento dos animais envolvidos. Com o advento de novas tecnologias, são propostas técnicas alternativas que se abstém da utilização destes. Mas que não são ainda largamente estudadas no Brasil. Portanto realizou-se uma breve revisão das relações ser - humano/natureza presentes historicamente na atividade científica. Foram respondidos questionários e entregues para a análise, no qual se teve o objetivo de averiguar a opinião em relação a esse assunto perante os experimentadores de um conceituado Centro de Pesquisas e verificar assim, a possibilidade da inserção de uma nova ética, a qual possa futuramente livrar todos os animais de qualquer sofrimento. Os pesquisadores apresentam de uma forma geral, uma pequena preocupação com a reflexão sobre a utilização de materiais alternativos, em contrapartida se mostram bastante preocupados com a utilização dos animais de forma ética, a fim de minimizarem o sofrimento causado

Água, preservação, uso e conservação: subsídios teórico-práticos para o ensino fundamental

O presente trabalho aborda os problemas relacionados com a escassez de água, os desafios para preservação, as perspectivas futuras e a conscientização da população. Mostra que grande parcela da população mundial já sofre com a falta de água potável, levando a conflitos pelos usos múltiplos da água. As diversas formas de poluição causam degradação dos rios, lagos e aquíferos prejudicando todas as formas de vida, desequilibrando todo o ecossistema. Novas tecnologias para agricultura, estratégias para aumentar as reservas de água potável tanto superficiais quanto subterrâneas e estratégias para o reaproveitamento de água são medidas encontradas para um consumo sustentável

O artista plástico e seus públicos na perspectiva da assessoria de relações públicas

This work aims to study and see the importance of building the image and reputation of the artist through a publishing of public relations, public recital, new technologies, media, cultural production and curatorial work. To this, we analyzed the history of the profession of public relations in Brazil. As well as their concepts, practices and definitions. Focus on work of publicist and cultural production sectors. The choice of theme is done by the need to understand the relationships. That intertwines in the art market and what media that best reaches in their audiences. Considering the artist-consumer relationship, and the relationship brand-artist and artist-public. And so, the importance of this advice means less explored public relations, for the creation of the brand concept for the artist before his public. Considered in this work as a gallery, art dealer, curator, media and consumers. In this context an analysis is done on diverse views on the market of the arts through specific interview. This interviews was made with professionals working in the cultural sector. And help to understand the communication segments that exist and the current conditions of the market in the context of competitiveness. As was considered the academic education of the public relations professional, it geared to the cultural context, the interviews with professional future. And then was considered that public relations presents itself as a proposal for better communication in the arts. They are concern to create concepts of brand identity-thinking artist and the best means for the artist to be present in this area

Relações Eficazes: a importância da comunicação eficaz nas organizações

This project aims to study and verify the importance of effective communication in contemporary organizations, considering current factors such as globalization, new technologies and market competition that make companies be always updated. The choice of the theme is due to the necessity to know that it is important to have an integrated communication between the employees and the customers, so that the established functions in the organizations occur positively. In this context, we present the concept of management, communication and organizational culture, focusing on the integration of business communication. The importance of the employee was also a focus of the study, involving the positioning of organizations. In this context, the case study is placed, considering that companies are characterized by carefully reading the feedback and reformulating the communication, making it effective as “Grendene” has done. Opposing to those ideas is “Terra” company. Thus, the project defends the importance to work on the communication, so that it becomes effective. During the project ways and means to manage communication are shown, so that it recognizes this need and become efficient, benefiting organizations and their audiences

Estudo acústico da variação da frase interrogativa, com destaque para o dialeto paulista

With the new computational technology, the studies of acoustic phonetics started to have a special place. This brought a new way of seeing the phenomenon and to deal with it in the phonetics and in the phonology. Such studies have been developing even more, recently, with a facilitated use of computational programs specially developed to the acoustic analysis of speech, such as PRAAT. Programs like this have been very interesting and useful recently. The acoustic models of analysis have influenced the way the researchers came to see and to interpret the prosodic phenomenon. The current project investigates the acoustic production of declarative and interrogative sentences from the “paulista” Portuguese. This study contributes for a more detailed description of the phenomenon, also becoming inserted in the chart of “intonational” descriptions of the Brazilian Portuguese. The subject of this current project is the acoustic study of some intonation aspects from the speaking Portuguese in Brazil, with a special place to the “paulista” dialect. The current project´s purpose is to make a specific study of interrogatives sentences through the acoustic data analysis of “paulista” dialect speakers

Influência da luz LED na cultura celular de Mieloma múltiplo murino–NS1 in vitro

A monoclonal antibody (mAb) is an important tool in medical biotechnology and the production of biopharmaceuticals, especially for disease diagnosis and treatment of infections, because the antibodies have a significant advantage over chemical agents used in conventional therapies . The last thirty years the technology of production of monoclonal antibodies developed mainly the technique of obtaining in vitro, but also of their production is laborious, the cost is high. A major element of the high cost of production is the fact that the long-term culture consumes a large amount of imported inputs with high added value. A major contribution of this work is to promote cell growth more quickly and efficiently. Currently, a great race to discover new technologies and techniques to synthesize new antibodies and significantly increase the production of murine mAbs. New technologies such as laser and LED are innovations and widespread in modern life, so much so that its use has proliferated worldwide, primarily in the medical field. Recent studies show a series of results from the influence of the LED light in biological tissues such as: increasing the rate of cell proliferation, increased production rate of fibroblasts, increasing the rate of synthesis of RNA and DNA synthesis of ATP, etc. To assess the contribution of the LED in the culture of Myeloma NS1murino compared to the standard procedure. - NS1 cells were provided and followed the criteria of culture medium of the Laboratory of Cellular Engineering Center of Botucatu (POPs). The same amount of cells was grown in bottles of 25 cm2 polystyrene Tissue Culture Treated, specifically marked and kept in special medium RPMI 1640 Gibco BRL  supplemented with fetal bovine serum 10%, essential amino acids and non-essential, glucose, insulin and antibiotics. It was used in LEDs Cromatek wavelength of 630nm, 475nm and 530nm. The groups were... (Complete abstract click electronic access below)

Falência renal aguda em pequenos animais

The pets, mostly dogs and cats are susceptible to a variety of situations that can lead to acute kidney failure, such as infection and intoxication, besides other common causes such as dehydration or other pre-existing diseases. The abrupt decrease in renal function in these animals characterizes a severe clinical condition and requires specialized veterinary medical care since it increases the death. Early diagnosis is an important factor for the survival of these animals and so is the appropriate treatment. New technologies on diagnosis and treatment of serious diseases in veterinary medicine have made acute renal failure successfully reversed by hemodialysis in cases where conventional therapy may not be effective. In cases like that, hemodialysis treatment may be the only chance of survival for the animals, which makes this therapy more and more important and necessary, especially in referral centers of veterinary assistance

Considerações gerais sobre os resíduos eletrônicos

As new technologies improve, people’s lives gain in comfort and accessibility. However, along with these technologies comes a growth in “soon to fall into disuse” product consume, either because they have reached the end of their life cycle, or because they were substituted by newer and more advanced models. These electronic wastes are still with no certain destination, and could be donated to welfare companies, but the majority is thrown in wide open dumping grounds or landfills, where they can contaminate water and soil with their toxic components. This work seeks to evaluate the e-waste concept, their impacts in the environment and human life, as well as the current national and international e-waste management and destination, finally reflecting on international decisions that would be appropriate for the Brazilian system.

Avaliação experimental de medidas de aceleração

Acceleration is a key parameter for engineering and is becoming increasingly important because of the need for companies to become more competitive in the market. Both applying new technologies to their products and optimizing their process lines with predictive maintenance and robotic automation. This study aims to analyze the quality of the signals obtained from a capacitive accelerometer. To do that a test rig was mounted, which consist of a shaker, fed by a signal generator, a linear potentiometer and a capacitive accelerometer; for the signal acquisition was used a acquisition board and the Labview software, in order to integrate twice the signal from the accelerometer and compare it with the sign of the potentiometer. This work also demonstrates the impact of acquired signal processing as well as techniques of pre and post processing of signal via software GNU/Octave

Processamento do compósito de fibra de capim-sapê / epóxi e avaliação da resistência à flexão “t” de Student

In recent years a great worldwide interest has arisen for the development of new technologies that enable the use of products with less environmental impact. The replacement of synthetic fiber plants is a possibility very important because this fiber is renewable, biodegradable and few cost and cause less environmental impact. Given the above, this work proposes to develop polymeric composites of epoxy resin and study the behavior of these materials. Both, the epoxy resin used as matrix in the manufacture of sapegrass fiber composite, as tree composites formed by: epoxy/unidirectional sapegrass long fiber, 75% epoxy/25% short fiber, by volume, and 80% epoxy/20% short fiber, by volume, were characterized by bending, and the composites produced with short fibers random were inspected by Optical Microscopy and Acoustics Inspection (C-Scan). For the analysis of the sapegrass fiber morphology, composites 75% epoxy/25% short fiber (sheet chopped) and 80% epoxy/20% short fiber images were obtained by optical microscope and the adhesion between polymer/fiber was visualized. As results, the flexural strength of composites epoxy/unidirectional long fibers, 75% epoxy/25% short fiber and 80% epoxy/20% short fiber were 70.36 MPa, 21.26 MPa, 25.07 MPa, respectively. Being that composite showed that the best results was made up of long fibers, because it had a value of higher flexural strength than other composites analyzed

Comunicação organizacional na ambiência da internet: um estudo sobre a atuação de três empresas de médio a grande porte de Bauru

This study aims to examine the changes occurring in organizational communication activities with the arrival of the Internet. The intention is to know how companies and their communication professionals have adapted to it and how they are making use of new digital technologies, especially social media. The study also allows know what strategies they are using to reach your target audience on the Internet, including those targeting mobile devices. For this, a survey was conducted with medium to large companies in Bauru (state of São Paulo), to see how it are acting in the online environment and what its perception regarding their image, visibility and positioning on Web

Síntese e aplicações de inibidores peptídicos de topoisomerases associados a sistemas de liberação controlada de fármacos

O uso de novas tecnologias para o desenvolvimento de medicamentos constitui uma estratégia promissora no campo da biotecnologia. Nesse sentido, peptídeos com efeito antimicrobiano, produzidos por plantas, animais e microrganismos estão sendo utilizados como modelos para o desenvolvimento de novos medicamentos com aplicações em saúde. Resultados promissores têm sido obtidos em relação à inibição da atividade das enzimas bacterianas DNA girase e topoisomerase IV por derivados peptídicos de toxinas bacterianas, comprovados em ensaios in vitro. Porém, ensaios in vivo não demonstraram reprodutibilidade, basicamente devido à baixa permeabilidade da célula bacteriana a estes compostos. Desta forma, o objetivo deste projeto consiste em aplicar sistemas eficientes para promover o acesso de moléculas peptídicas sintéticas derivadas de toxinas bacterianas, ao meio intracelular e, consequentemente, aos seus alvos intracelulares: as enzimas DNA girase e/ou topoisomerase IV. Com isso, pretendemos solucionar a barreira técnica em que se encontram as aplicações dessa classe de biomoléculas como precursores de novos agentes antibacterianos, o que certamente causaria um importante avanço nas pesquisas desenvolvidas pelo grupo

Melhorias na linha de planificadora contínua com o uso de transporte por sucção e enrolador de refiles

With the market more and more disputed and negotiations where the customer is the main factor who decides whether the companies have conditions or not to dispute the market, industries must search improvements in products and processes targeting lower costs and better quality. With that in mind, this work will study the actual situation of a line of Tension Leveler, after cold mill process, for aluminum coil, and search new technologies, precisely the Scrap Baller machine, which will raise the quality level and the line’s productivity. It will be analyzed the justifications (reasons) for these new technologies, the history, the involved concepts, the operation, functions, the material that will be tension leveled, the limitations and tech and economic viability in comparison with the actual system. Also it will be taken a brief about the aluminum coil production in Brazil, especially the ones which destiny is aluminum beverage can, and the recycling process, that is very well done in Brazil, worldwide leader in aluminum recycling

Proposição de uma nova vacina para Brucelose bovina usando uma abordagem biotecnológica

A utilização de novas tecnologias empregando a biologia molecular busca superar os principais problemas encontrados nas vacinas atualmente comercializadas no combate à brucelose bovina. Desta forma, a identificação de proteínas imunogênicas e a posterior transformação dos genes correspondentes em micro-organismos competentes tem sido um dos principais alvos para o desenvolvimento de novas formas de controle da infecção. O presente trabalho tem como objetivo propor, em base teórica, uma vacina de eficácia e segurança superiores às encontradas atualmente no mercado contra a brucelose bovina, antropozoonose contagiosa provocada principalmente pela espécie Brucella abortus. Essa enfermidade produz infecção característica em bovinos e bubalinos e é infecciosa ao homem, causando doença crônica que leva à incapacidade parcial ou total para o trabalho. Por ter distribuição universal, acarreta problemas sanitário e de saúde pública importantes e grandes prejuízos econômicos. A vacina proposta visa o desenvolvimento de microorganismos transformados contendo genes de proteínas de potencial imunológico que, após purificação, são usadas para o combate da doença. As proteínas recombinantes abordadas no presente estudo são as proteína ribossomal L7/L12 e a lumazina sintetase que, ao serem utilizadas em uma vacina subcelular, diferente das comercializadas atualmente, induzem resposta de longa duração, não induzem a produção de anticorpos que interfiram no diagnóstico e não são patogênicas ao homem.