973 resultados para exterior domains


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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Este artigo é dedicado ao estudo da controlabilidade finito-aproximada para a equação não linear de transferência de calor em domínios com fronteira móvel. A demonstração do resultado principal baseia-se no princípio de continuação única de Carolina Fabre 1996 e em argumentos de ponto fixo do tipo Leray-Schauder.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The easy access to information has been accelerating even more business competitiveness nowadays. To turn a foreign trade company into a more competitive company by improving its services, this work aims the analysis of the Supply Chain processes to enable greater productivity. Using powerful tools of great historical success in the business world – such as Flowcharts, VSM Lean and PDCA –, a structure was created that adapted its main concepts and produced a method which enabled not only improvements on modified processes but also on the subsequent ones. Productivity data were collected, where evidence of quantitative improvements were found in the expedition macro process. Due to a process analysis theme, this paper gives also the thought about process approach, vital step to create a future Quality Management System

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This work aims to evaluate the different trajectories in terms of production structure, technological capabilities and performance in international trade of pharmaceutical industries in Brazil and India. For this, we build international trade indicators, based on data provided by the COMTRADE, the UN database for trade. Through the indicators, it is observed that the countries have different results in the catch-up process of the pharmaceutical industry. India has built a productive structure strongly based on generic drugs, with which it is able to greatly meet domestic demand and export to many countries worldwide. Brazil remains in a position of dependence of foreign production, with a high level of imports and exports to the region of Latin America

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Amino acids play essential roles in both metabolism and the proteome. Many studies have profiled free amino acids (FAAs) or proteins; however, few have connected the measurement of FAA with individual amino acids in the proteome. In this study, we developed a metabolomics method to comprehensively analyze amino acids in different domains, using two examples of different sample types and disease models. We first examined the responses of FAAs and insoluble-proteome amino acids (IPAAs) to the Myc oncogene in Tet21N human neuroblastoma cells. The metabolic and proteomic amino acid profiles were quite different, even under the same Myc condition, and their combination provided a better understanding of the biological status. In addition, amino acids were measured in 3 domains (FAAs, free and soluble-proteome amino acids (FSPAAs), and IPAAs) to study changes in serum amino acid profiles related to colon cancer. A penalized logistic regression model based on the amino acids from the three domains had better sensitivity and specificity than that from each individual domain. To the best of our knowledge, this is the first study to perform a combined analysis of amino acids in different domains, and indicates the useful biological information available from a metabolomics analysis of the protein pellet. This study lays the foundation for further quantitative tracking of the distribution of amino acids in different domains, with opportunities for better diagnosis and mechanistic studies of various diseases.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The objective of this work is to stimulate a debate about the idea of a possible foreign language policy. It seeks to do so from an overview of the structural changes of recent decades - those affecting the economy, information and communication technologies, geopolitics and identities - in order to draw attention to the renewed importance and the role that the language management issues are assuming in this new context. Considering the foreign language policy a theoretical and practical essential tool for the management of language in a globalized world, the focus of the discussion rests on four main aspects: the origins of the notion of foreign language policy; the relationship with the foreign policy of the State; its effectiveness through the intervention on corpus, status and acquisition of the language; and the possibility of their formulation by agents other than the State

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The objective of this work is to stimulate a debate about the idea of a possible foreign language policy. It seeks to do so from an overview of the structural changes of recent decades - those affecting the economy, information and communication technologies, geopolitics and identities - in order to draw attention to the renewed importance and the role that the language management issues are assuming in this new context. Considering the foreign language policy a theoretical and practical essential tool for the management of language in a globalized world, the focus of the discussion rests on four main aspects: the origins of the notion of foreign language policy; the relationship with the foreign policy of the State; its effectiveness through the intervention on corpus, status and acquisition of the language; and the possibility of their formulation by agents other than the State