Dipolo e escoamento uniforme: escoamento em torno de um cilindro circular

The study of movements of ideals fluids is more simple that the viscous fluids because do not have the presence of tension of shear. The normal tensions are the one that must be considered in this analysis. The theory corresponding to these flows is the same used in other fields of the physics called Theory of Potentials Fields, which the vector identity is fundamental. Any flow into irrotational (null vorticity) physically possibly has a current function and a potential of velocity that satisfied the equation of Laplace. Reciprocally, any solution of equation of Laplace represents a current function or a potential of velocity of a flow into physically possible. Once the equation of Laplace is linear, the addiction of any numbers of solutions is also a solution. So, several potentials flows into can be constructed superposing configurations of elementary flows into. The purpose of the superposition of elementary flows into is a production of similar configurations to those of practical interest. The combination of mathematical elegancy with utility in the potential flow into attracted many for its study. Some of the most famous mathematician of history studied the theory and application of “hydrodynamic”, how was called the potential fluid into before 1900

Effects of lithium on the proliferation and migration of neuroblasts in the rostral migratory stream in adult mice

The discovery of neurogenesis in adult brains opened the possibility of cellular therapy strategies for the treatment of neurodegenerative diseases, such as Alzheimer’s disease. Neurogenesis in the adult brain occurs in two areas: subgranular zone of the hippocampus and subventricular zone (SVZ) of the lateral ventricles. Neurons that originate from the SVZ migrate to the olfactory bulb (OB) through the rostral migratory stream (RMS). In Alzheimer’s disease, there is a progressive neuronal dysfunction and degeneration, resulting in brain atrophy and cognitive impairments including olfactory dysfunction. Several studies have demonstrated that pharmacological treatment with lithium exerts positive effects on adult neurogenesis, and one pathway seems to be the modulation of factors that regulate the migration of neuroblasts. The objective of this study was to investigate whether treatment with lithium promotes the increase of migratory neuroblasts using as parameter the RMS. Adult male C57BL/6 mice were divided into control and lithium-treated groups. The animals were treated for 6 weeks and, at four different time points, i.e., 10 days, 7 days, 3 days and 1 day before the end of treatments, they received an injection of BrdU (cell proliferation marker). The animals were sacrificed by perfusion fixation and the brains were immunohistochemically labeled for BrdU for analysis of migrating neuroblasts in the RMS. The results showed that the number of BrdU+ cells in the RMS was not significantly different between the two groups, suggesting that lithium, alone, is not capable of increasing the number of neuroblasts migrating from the SVZ to the OB

Monocyte migration driven by galectin-3 occurs through distinct mechanisms involving selective interactions with the extracellular matrix

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Nitric oxide and brazilian propolis combined accelerates tissue repair by modulating cell migration, cytokine production and collagen deposition in experimental leishmaniasis

The fact that drugs currently used in the treatment of Leishmania are highly toxic and associated with acquired resistance has promoted the search for new therapies for treating American tegumentary leishmaniasis (ATL). In this study, BALB/c mice were injected in the hind paw with Leishmania (Leishmania) amazonensis and subsequently treated with a combination of nitric oxide (NO) donor (cis-[Ru(bpy)(2)imN(NO)](PF6)(3)) (Ru-NO), given by intraperitoneal injection, and oral Brazilian propolis for 30 days. Ru-NO reached the center of the lesion and increased the NO level in the injured hind paw without lesion exacerbation. Histological and immunological parameters of chronic inflammation showed that this combined treatment increased the efficacy of macrophages, determined by the decrease in the number of parasitized cells, leading to reduced expression of proinflammatory and tissue damage markers. In addition, these drugs in combination fostered wound healing, enhanced the number of fibroblasts, pro-healing cytokines and induced collagen synthesis at the lesion site. Overall, our findings suggest that the combination of the NO donor Ru-NO and Brazilian propolis alleviates experimental ATL lesions, highlighting a new therapeutic option that can be considered for further in vivo investigations as a candidate for the treatment of cutaneous leishmaniasis.

Circular, elliptic and oval billiards in a gravitational field

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Impairment of neutrophil migration to remote inflammatory site during lung histoplasmosis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The evolution of a Pluto-like system during the migration of the ice giants

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Albumin-induced circular dichroism in Congo red: applications for studies of amyloid-like fibril aggregates and binding sites

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effect of gamma irradiation on caprolactam migration from multilayer polyamide 6 films into food simulants: development and validation of a gas chromatographic method

A GC method to determine caprolactam in water, 15 ethanol, and olive oil food simulants was developed and validated. Linear ranges varied from 0.96 to 642.82 g/mL for water, 0.64 to 800.32 g/mL for 15 ethanol, and 1.06 to 1062.34 g/g for olive oil, with correlation coefficients higher than 0.999. Method precision studies showed RSD values lower than 5.45, while method accuracy studies showed recovery from 72 to 111 for all simulants. The effect of gamma irradiation on caprolactam migration from multilayer polyamide 6 (PA-6) films intended for cheese into water, 15 ethanol, olive oil, and 3 acetic acid simulants was also studied. For migration assay, non-irradiated and irradiated (12 kGy) films were placed in contact with the simulant and exposed at 40C for 10 days. The validated method was used to quantify caprolactam migration from multilayer PA-6 films into the simulants, which ranged from 1.03 to 7.59 mg/kg for non-irradiated films, and from 4.82 to 11.32 mg/kg for irradiated films. Irradiation caused almost no changes in caprolactam levels, with the exception of olive oil, which showed an increase in the caprolactam level. All multilayer PA-6 films were in accordance with the requirements of the legislation for caprolactam migration.

Avaliação da migração de nifas de Scaptocoris carvalhoi Becker, 1967 (Hemiptera, Cydnidae) em plantas de importância econômica e invasora em teste com oportunidade de escolha

One of the factors that affect the control of brown - roots environmental bedbug is the wide availability of plant species. Thus, this study aimed to evaluate the migration of nymphs of the brown - roots between plant species of economic importance and invasive stinkbug. Eight species of plants have been established in a set formed by eight circular PVC containers, connected symmetrically with free communication to a central circular container. The experiment was arranged in a completely randomized design and consisted of eight treatments and six replications. The test evaluations were performed on 15o , 30o , 45o and 60o days after the release of the nymphs, by counting the insects that migrated to the roots of different plants. It was observed that by the 30o day of early release nymphs, no significant differences (P < 0,05) in the choices nymph by plants. B. alata at 15 days of initial release and B. alata and grass-dictyoneura at 30 days were plants that had higher migration. All counts were carried out on 45o and 60o days, the migration of U. brizantha cv. Marandu presented significantly higher than all other species tested plants nymphs.