Alignment of the CMS silicon tracker during commissioning with cosmic rays

The CMS silicon tracker, consisting of 1440 silicon pixel and 15 148 silicon strip detector modules, has been aligned using more than three million cosmic ray charged particles, with additional information from optical surveys. The positions of the modules were determined with respect to cosmic ray trajectories to an average precision of 3-4 microns RMS in the barrel and 3-14 microns RMS in the endcap in the most sensitive coordinate. The results have been validated by several studies, including laser beam cross-checks, track fit self-consistency, track residuals in overlapping module regions, and track parameter resolution, and are compared with predictions obtained from simulation. Correlated systematic effects have been investigated. The track parameter resolutions obtained with this alignment are close to the design performance. © 2010 IOP Publishing Ltd and SISSA.

Performance of the CMS drift tube chambers with cosmic rays

Studies of the performance of the CMS drift tube barrel muon system are described, with results based on data collected during the CMS Cosmic Run at Four Tesla. For most of these data, the solenoidal magnet was operated with a central field of 3.8 T. The analysis of data from 246 out of a total of 250 chambers indicates a very good muon reconstruction capability, with a coordinate resolution for a single hit of about 260 μm, and a nearly 100% efficiency for the drift tube cells. The resolution of the track direction measured in the bending plane is about 1.8 mrad, and the efficiency to reconstruct a segment in a single chamber is higher than 99%. The CMS simulation of cosmic rays reproduces well the performance of the barrel muon detector. © 2010 IOP Publishing Ltd and SISSA.

Performance study of the CMS barrel resistive plate chambers with cosmic rays

In October and November 2008, the CMS collaboration conducted a programme of cosmic ray data taking, which has recorded about 270 million events. The Resistive Plate Chamber system, which is part of the CMS muon detection system, was successfully operated in the full barrel. More than 98% of the channels were operational during the exercise with typical detection efficiency of 90%. In this paper, the performance of the detector during these dedicated runs is reported. © 2010 IOP Publishing Ltd and SISSA.

Performance of the CMS cathode strip chambers with cosmic rays

The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47μm to 243μm. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns. © 2010 IOP Publishing Ltd and SISSA.

Precise mapping of the magnetic field in the CMS barrel yoke using cosmic rays

The CMS detector is designed around a large 4 T superconducting solenoid, enclosed in a 12 000-tonne steel return yoke. A detailed map of the magnetic field is required for the accurate simulation and reconstruction of physics events in the CMS detector, not only in the inner tracking region inside the solenoid but also in the large and complex structure of the steel yoke, which is instrumented with muon chambers. Using a large sample of cosmic muon events collected by CMS in 2008, the field in the steel of the barrel yoke has been determined with a precision of 3 to 8% depending on the location. © 2010 IOP Publishing Ltd and SISSA.

Estudo de frequências alélicas de STRs do cromossomo X na população brasileira de Araraquara-SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação do emprego de um novo método de triagem molecular da síndrome do cromossomo X frágil em indivíduos brasileiros

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo de polimorfismo do cromossomo x na população da região sudeste do Brasil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Revisão taxonômica do gênero Hassar Eigenmann & Eigenmann, 1888, com a descrição osteológica de Hassar orestis (Steindachner, 1875) (Siluriformes, Doradidae)

O gênero Hassar (Doradidae) é um grupo natural de Siluriformes Neotropical. No presente trabalho foi realizada revisão taxonômica do referido gênero com a descrição osteológica de Hassar orestis, espécie-tipo do gênero. Este estudo foi fundamentado no levantamento e análise de caracteres morfológicos, morfométricos, merísticos e de padrão de coloração para o reconhecimento das espécies válidas e conseqüentes diagnoses e redescrições. Foram analisados 727 exemplares, provenientes de instituições nacionais e estrangeiras, envolvendo indivíduos preservados em álcool, preparados para esqueleto seco, diafanizados, radiografados e fotografados. Os exemplares foram analisados diretamente ou com auxílio de microscópio-estereoscópico e câmara clara. Medidas foram feitas, preferencialmente, do lado esquerdo do indivíduo. A descrição osteológica de Hassar orestis foi fundamentada na análise de 23 exemplares de instituições nacionais e estrangeiras e foi dividida em grupos funcionais osteológicos que são: elementos do neurocrânio, arco mandibular, arco hióide, arcos branquiais, esqueleto axial, placas nucais e nadadeira dorsal, sistema látero-sensorial e esqueleto apendicular. Os dados foram digitalizados e armazenados em formato de planilhas. Os resultados mostraram que Hassar é formado por duas espécies válidas: H. orestis e H. affinis. Hassar orestis é a espécie-tipo, tendo como sinônimo H. ucayalensis. Hassar affinis tem como sinônimos H. wilderi, H. iheringi e H. woodi. Hassar orestis e H. affinis se diferenciam pela posição do 1° espinho medial (no escudo infranucal ou entre o 1° e 8° escudo lateral vs. entre o 9° e 16° escudo lateral), número de escudos laterais providos de espinho medial (24 a 33 vs. 18 a 23) e pelos divertículos marginais filiformes da bexiga natatória (distintamente maiores vs. reduzidos ou ausentes). Os adultos (> 14 cm) de H. orestis e H. affinis diferiram pela altura do pedúnculo caudal (4,11-5,71% SL vs. 5,73 -7,63% SL) e pelo tamanho da pálpebra adiposa (conspícua e alongada na borda anterior dos olhos vs. tênue na borda anterior dos olhos). Não houve diferenças morfológicas, morfométricas e merísticas entre jovens e adultos da mesma espécie. As espécies apresentaram o mesmo padrão de coloração. Exemplares de H. orestis (N=551) possuem mancha enegrecida subterminal nos primeiros raios da nadadeira dorsal, diferentemente de H. affinis (N=176) cuja mancha pode ser subterminal ou terminal. A presença de prolongamento cartilaginoso no primeiro raio da nadadeira dorsal, em alguns machos de H. orestis, corroborou o dimorfismo sexual para espécie. Exemplares de H. orestis, provenientes dos rios Amazonas, Solimões e Negro, diferem da população do rio Branco e das Bacias dos rios Essequibo e Orinoco pela presença ou não de espinhos nos escudos timpânicos e no escudo infranucal. Não há diferença quanto à bexiga natatória dessas populações. A distribuição de H. affinis foi ampliada para os rios Solimões, Tapajós, baixo e alto Xingu, Tocantins, Araguaia, Parnaíba e Sistema Pindaré-Mearim. Hassar affinis e H. orestis apresentam ampla distribuição, parcialmente disjunta, com uma área de simpatria. A descrição osteológica da espécie-tipo proporcionou um melhor conhecimento anatômico do grupo, que serve de dado básico para trabalhos como anatomia, ontogenia, ecomorfologia e futuros eventuais trabalhos de sistemática e taxonomia.

Aplicação da difração de raios X por policristais e do método de Rietveld de refinamento de estruturas cristalinas no estudo de polimorfos cristalinos de fármacos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Interploidy hybridization in sympatric zones: the formation of Epidendrum fulgens x E. puniceoluteum hybrids (Epidendroideae, Orchidaceae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Aparelho Herbst x osteotomia sagital mandibular bilateral no tratamento do padrão II, classe II, divisão 1 em adultos: relato de casos

Two treatment options are available for adult patients with skeletal Class II malocclusion caused by mandibular deficiency: combined mandibular advancement surgery and orthodontic treatment or mandibular advancement appliance. This study aimed to analyze the effects of two therapeutic modalities of Class II malocclusion treatment with mandibular deficiency. Two distinct individuals with Class II malocclusion division 1 and mandibular deficiency were treated after growth spurt. The first individual used the Herbst appliance as a therapeutic option and the second individual was treated with bilateral sagittal osteotomy. The cephalometric, occlusion and face results were evaluated for both individuals. Correction of Class II malocclusion was observed on both Herbst and surgery patients resulting on a normal occlusal relationship with normal overjet and overbite. Therefore it was concluded that Herbst appliance can be used to treat borderline skeletal Class II in adult patients.

Linhagens de alface crespa resistentes a Bremia lactucae e interação genótipo x ambiente

Pós-graduação em Agronomia (Genética e Melhoramento de Plantas) - FCAV

Trace elements as tumor biomarkers and prognostic factors in breast cancer: a study through energy dispersive x-ray fluorescence

Background The application and better understanding of traditional and new breast tumor biomarkers and prognostic factors are increasing due to the fact that they are able to identify individuals at high risk of breast cancer, who may benefit from preventive interventions. Also, biomarkers can make possible for physicians to design an individualized treatment for each patient. Previous studies showed that trace elements (TEs) determined by X-Ray Fluorescence (XRF) techniques are found in significantly higher concentrations in neoplastic breast tissues (malignant and benign) when compared with normal tissues. The aim of this work was to evaluate the potential of TEs, determined by the use of the Energy Dispersive X-Ray Fluorescence (EDXRF) technique, as biomarkers and prognostic factors in breast cancer. Methods By using EDXRF, we determined Ca, Fe, Cu, and Zn trace elements concentrations in 106 samples of normal and breast cancer tissues. Cut-off values for each TE were determined through Receiver Operating Characteristic (ROC) analysis from the TEs distributions. These values were used to set the positive or negative expression. This expression was subsequently correlated with clinical prognostic factors through Fisher’s exact test and chi-square test. Kaplan Meier survival curves were also evaluated to assess the effect of the expression of TEs in the overall patient survival. Results Concentrations of TEs are higher in neoplastic tissues (malignant and benign) when compared with normal tissues. Results from ROC analysis showed that TEs can be considered a tumor biomarker because, after establishing a cut-off value, it was possible to classify different tissues as normal or neoplastic, as well as different types of cancer. The expression of TEs was found statistically correlated with age and menstrual status. The survival curves estimated by the Kaplan-Meier method showed that patients with positive expression for Cu presented a poor overall survival (p < 0.001). Conclusions This study suggests that TEs expression has a great potential of application as a tumor biomarker, once it was revealed to be an effective tool to distinguish different types of breast tissues and to identify the difference between malignant and benign tumors. The expressions of all TEs were found statistically correlated with well-known prognostic factors for breast cancer. The element copper also showed statistical correlation with overall survival.

Resgates e abandonos do passado na prática musical litúrgica católica no Brasil entre os pontificados de Pio X e Bento XVI (1903-2013)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)