Aquisição/aprendizagem de LE na infância: a produção de enunciados em inglês por crianças de 3 a 5 anos

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Desenvolvimento de ferramentas pedagógicas para identificação de escolares de risco para a dislexia

PURPOSE: The development and application of collective pedagogical activities to assess phonological skills in pre-readers and beginning readers and could serve as potential screening tools to help in the early identification of students at risk for dyslexia. METHODS: The FAE tasks (alternative tools for educators) were built on classical phonological tasks known as sound categorization and in the Protocol for Cognitive-Linguistic Skills. FAE tasks basically consisted of matching pictures as well as pictures to spoken words according to their phonological similarity in the onset (alliteration) or rhyme and were given to 45 students on the first grade, of both genres and 7.3 years old on average. RESULTS: The protocol proved to be effective, confirming that phonological awareness, verbal working memory and rapid naming abilities constitute the main risk factors for dyslexia, and to which the FAE tasks were more strongly correlated jointly with the phonemic discrimination. FAE tasks were also strongly correlated with literacy skills. CONCLUSIONS: Students at risk for dyslexia can be efficiently identified through scientifically developed pedagogical tools, adapted and tested for the Brazilian's educational reality. This is a promising research field with the potential to help in avoiding the currently excessive number of students mistakenly labeled as having learning disabilities and improperly referred to specialized public services, as well as to indicate the more appropriate theoretical-empirical framework to guide our educational policies.

Preposições em textos do gênero notícia na imprensa paulista: norma e uso no ínicio do século XX

This paper proposes a reflection on processes of variation and change that occurred with the portuguese prepositions a, ate, em and para, taken as a parameter for answers in a broader context, the confrontation between the norm and use and between standard and linguistic variation. We conducted the study based on a corpus composed of all occurrences of the prepositions in question removed news of the newspaper O Combate and O Estado de Sao Paulo. Whereas the main objective of the study is to present and describe the use of these particles in newspaper articles of the Imprensa Paulista, data were collected and quantified by using the statistical package GOLDVARB, and interpretation of results relied (i) assumptions regarding the process variation in the use of prepositions and prepositions replace weak, as the preposition to, for strong prepositions (para, em, até), (ii) in comparison with the grammatical rule in effect at the time, (iii) and in the search for the existence of some historical factor that justifies the selection of a preposition rather than another. Among the hypotheses, we investigate the relationship between these prepositions and whose kind of preachers they introduce supplements: the direction of motion (abstract or concrete) or transfer (material and verbal / perceptual). This theoretical perspective was the Labovian sociolinguistics (Labov, 1972, 1994), which defines the linguistic variable as a representation of two or more different ways to convey a certain information content, being necessary to define it the following criteria set exact number of variants to establish all the multiplicity of contexts in which it appears; develop a quantitative index for measuring the values of variables

Lematização verbal em juruna: discussões lexicográficas

The production of a dictionary always generates controversy about decisions to be taken by the lexicographer. They are based – a priori – in previous theoretical and methodological choices. What we mean by dictionary? Why making certain choices rather than others? How to reconcile (if there is a reconciliation) the different approaches to describe the lexicon? The objective here is to contribute with theoretical and methodological reflections related to the Juruna Lexicography (Yudjá), as well as for lexicographical studies camp. This text addresses critical points of dictionaries production processes – if we may so call it – the history of the act of making a dictionary, so we can discuss choices to be taken to the entries of verbs in the Juruna-Portuguese bilingual dictionary assembly provided as a long term project result, in which some collaborators are working, including community’s indigenous. The work contains sections that will raise historical and linguistic discussions about the compilation of a dictionary and how this act binds to the applicability for the subjects that use this instrument firming / mobilizer of the lexicon visions. The focus here will be to discuss the verbs entries in the Juruna dictionary (stemming), taking lexicographical history as a contributor to certain choices of dictionaries production nowadays, whether for mother tongue, for foreign language, specialized lexicons, semantic groups, and systematizations for languages that are starting/beginning a first publication of dictionaries

A variação sócio-cultural e o ensino de língua portuguesa no ensino fundamental: por uma pedagogia sensivelmente cultural

This study aimed to gather information about the social and linguistic reality of students 1. years of elementary school and community that came, in order to identify aspects of their lexical phonological levels, morphological and morphosyntactic and thus identify and describe the alternative variants of non-standard rule. The methodology chosen was that of variational sociolinguistics addressing quantitative and qualitative aspects in the treatment of the data collected through participant observation and audio recordings of speeches of the students. The results indicate that the level of phonological variants are the most frequent in the speech of students. Because the literacy phase, how the student speaks serves you a guide to the act of writing, so it is necessary to work with the students the difference between oral and written form and monitoring of these two modes according to the context of the discourse

Usos não-padrão das estratégias de relativização no português brasileiro: hipercorreção e estilo

This study focuses on the current use of the relative pronoun qual and variants or alternatives (o/os/a/as/ qual/quais, preceded or not by prepositions) in Brazilian Portuguese concerning mainly on the phenomenon of hypercorrection. As a theoretical basis, it was used the study of William Labov about the phenomenon and also the rules of use of this pronoun present in both traditional grammars and linguistic studies. It was performed a qualitative analysis of a corpus of written language with the intention of describing the different uses of the pronoun, and looking for their possible motivations. There were also found different types of occurrences of hypercorrection, which has led to propose a scale of uses of this relative pronoun, which reveals an increasing loss of its functions towards an use as an index of prestige. It discusses also the stylistic factor as a potential motivator of this phenomenon

Investigação dos genes CNR1 e AKT1 como possíveis fatores de risco/proteção para a esquizofrenia

A fisiopatologia da esquizofrenia parece envolver uma complexa interação entre vulnerabilidades genéticas e fatores de risco ambientais. O uso de Cannabis tem sido apontado como um destes fatores, que contribui para o surgimento de sintomas psicóticos em indivíduos predispostos e piora o curso da doença pré-estabelecida. O sistema endocanabinóide está envolvido neste processo, podendo apresentar possíveis implicações na manifestação de sintomas. O presente trabalho teve como objetivo geral verificar se variantes dos genes CNR1 (codificador do receptor endocanabinóide tipo 1) e AKT1 (codificador de proteína serina-treonina quinase), individualmente ou interativamente, e o uso de Cannabis podem ser fatores de risco para a esquizofrenia e para a refratariedade ao tratamento com antipsicóticos. Foram estudados 202 pacientes portadores de esquizofrenia e 277 indivíduos saudáveis. Os polimorfismos rs1049353 (G/A) e rs806380 (A/G) do gene CNR1 e os rs2494732 (C/T) e rs1130233 (A/G) do gene AKT1 foram genotipados por meio da técnica de PCR (polymerase chain reaction) em tempo real com sistema de detecção Taqman®. Tais polimorfismos foram correlacionados ao diagnóstico de esquizofrenia e a outras variáveis, tal como o uso de Cannabis, resposta ao tratamento e subtipos da doença. Também foi realizada análise de estratificação populacional a partir de marcadores genéticos escolhidos para a população brasileira a fim de correção estatística de fatores confundidores relacionados a diferenças étnicas. Foi visto uma influência positiva da idade de acometimento em pacientes refratários quando comparados com os pacientes respondedores (p = 0,006), confirmando os dados da literatura que sugerem uma idade de acometimento mais precoce da doença em portadores de esquizofrenia refratária. A interação dos genótipos AA do polimorfismo rs806380...(Resumo completo, clicar acesso eletrônico abaixo)

Avaliação de métodos de triagem e de detecção fenotípica de ß-lactamase de espectro ampliado (ESBL)

The catalytic function of extended-spectrum β-lactamases can result in high degrees of bacterial resistance to β-lactamic antimicrobials and in the emergence of ESBL among the members of Enterobacteriaceae family, especially Klebsiella pneumoniae and Escherichia coli. This occurs due to the dissemination and emergence of new variants of these enzymes caused by the high utilization of antibiotics like broad-spectrum cephalosporins. The ESBL are β-lactamases capable of conferring bacterial resistance to the penicillins, 1st, 2nd and 3rd generation cephalosporins, and aztreonam (but not cephamycins and carbapenems) through the hydrolysis of these antibiotics. In view of this phenomenon, the exact screening and detection of the producers of ESBL are essential for the appropriate selection of the antimicrobial therapy. The purposes of this study were to evaluate the best antimicrobial for the selection of ESBL producers and to determine the best method for the detection of such microorganisms. We evaluated 200 sequential bacterial samples including the species Klebsiella pneumoniae (56.5%), Escherichia coli (34%), Proteus mirabilis (8.5%) and Klebsiella oxytoca (1%), previously characterized as ESBL producers between February and September 2008 in the Laboratory of Microbiology, Botucatu Medical School - UNESP, Botucatu, São Paulo State, Brazil. To select the ESBL-producer bacteria, we used the disks recommended by CLSI 2008, aztreonam (ATM), cefpodoxime (CPD), ceftriaxone (CRO), cefotaxime (CTX) and ceftazidime (CAZ), besides cefepime (FEP). ESBL production was confirmed by three methods: double disk screening, ESBL Etest®, and Vitek® automated system. The disks employed in the double disk screening were: penicillin associated with β-lactamase inhibitor, amoxicillin-clavulanic acid, and two β-lactamic antibiotics, ceftazidime and cefotaxime...(Complete abstract click electronic access below)

A abordagem do voseo em materiais didáticos brasileiros de ensino do espanhol como língua estrangeira

This work discusses the importance of the language varieties in the Spanish language to the process of teaching and learning Spanish as a foreign language (ELE), focusing on the approach, ie, how to deal with the phenomenon voseo in Brazilian textbooks. It presents a brief historical overview on the arising of this language and its implementation in Latin America. From an educational approach that values a good development of communicative competence, it’s driven to a presentation of the Spanish schoolbooks selected by PNLD for the year 2012, as well as an observation of activities that demonstrate the phenomenon called voseo, in other words, the use of the variety of the pronoun vos instead of tú for the treatment of the second person. Given the vast range of Spanish courses as a foreign language for high school students, and the growing interest of young people in learning a second language, this study addresses the importance of developing the communicative competence of a foreign language

Correlação entre aneuploidia cromossômica em espermatozóides e taxa de implantação embrionária: subtitulo

Infertility is directly related to chromosomal abnormalities in germ cells. Among them, the aneuploidies are the most frequent chromosomal abnormalities and responsible for embryo implantation failures, miscarriages, fetal losses and newborns with congenital malformations, mental disability and neuropsychomotor developmental delay. Male patients with normal somatic karyotype may present different rates of aneuploidies in sperm, resulting in abnormal embryos. This study aimed to correlate the frequency of chromosomal aneuploidies in spermatozoa with embryo implantation rate in couples undergoing assisted reproductive techniques. The methodology has included chromosomal analysis by GTG banding and molecular cytogenetic study using Fluorescent In Situ Hybridization technique for evaluation of chromosomes 9, X and Y in germ cells of 22 patients referred to the Human Reproduction Service of the Clinical Hospital FMRP-USP. Embryo implantation rates were determined by hormonal evaluation in maternal peripheral blood and ultrasound confirmation. Two patients presented abnormal karyotype, characterized by polymorphism of the heterochromatic region of the long arm of chromosome 9 and a satellite in the short arm of chromosome 22. Both alterations, usually considered variants of normality, have been related to infertility phenotype and miscarriages. Significant differences were detected between couples who presented pregnancy (group 1) and couples with embryo implantation failure (group 2), with higher frequency of aneusomy and diploidy of chromosome 9, as well as total aneuploidy in sperm of group 2 patients. Our results suggest a correlation between aneuploidy and embryo implantation rates, since the infertile group with reproductive failure has showed higher frequency of aneuploidy. Screening for aneuploidies detection in male germ cells should be included in order to decrease embryo implantation failures, miscarriages and fetuses with chromosomal ...

Detecção de Escherichia coli shigatoxigênica (STEC) e enteropatogênica (EPEC) em peixes de pisciculturas e de vida livre

Pós-graduação em Microbiologia Agropecuária - FCAV

Um estudo longitudinal sobre as hipersegmentações de palavras escritas nos anos finais do ensino fundamental

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O gênero acadêmico: resumos nas áreas de Antropologia, Linguística e Ciência Política

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O insumo linguístico oral em aulas de inglês como língua estrangeira para crianças: a fala do professor em foco

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Pirossequenciamento de alta cobertura da região hipervariável 1 do Vírus da Hepatite C

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)