960 resultados para University of New Brunswick
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Audit report of the State University of Iowa, Iowa City, Iowa, and its discretely presented component unit as of and for the years ended June 30, 2012 and 2011
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Special investigation of the University of Northern Iowa Events Complex Concessions for the period October 1, 2006 through March 31, 2012
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Ever since the pre-molecular era, the birth of new genes with novel functions has been considered to be a major contributor to adaptive evolutionary innovation. Here, I review the origin and evolution of new genes and their functions in eukaryotes, an area of research that has made rapid progress in the past decade thanks to the genomics revolution. Indeed, recent work has provided initial whole-genome views of the different types of new genes for a large number of different organisms. The array of mechanisms underlying the origin of new genes is compelling, extending way beyond the traditionally well-studied source of gene duplication. Thus, it was shown that novel genes also regularly arose from messenger RNAs of ancestral genes, protein-coding genes metamorphosed into new RNA genes, genomic parasites were co-opted as new genes, and that both protein and RNA genes were composed from scratch (i.e., from previously nonfunctional sequences). These mechanisms then also contributed to the formation of numerous novel chimeric gene structures. Detailed functional investigations uncovered different evolutionary pathways that led to the emergence of novel functions from these newly minted sequences and, with respect to animals, attributed a potentially important role to one specific tissue--the testis--in the process of gene birth. Remarkably, these studies also demonstrated that novel genes of the various types significantly impacted the evolution of cellular, physiological, morphological, behavioral, and reproductive phenotypic traits. Consequently, it is now firmly established that new genes have indeed been major contributors to the origin of adaptive evolutionary novelties.
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Report on the State University of Iowa, Iowa City, Iowa for the year ended June 30, 2012
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Report on Iowa State University of Science and Technology, Ames, Iowa, for the year ended June 30, 2012
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Report on the University of Northern Iowa for the year ended June 30, 2012
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Map of railroads and locations of new industries in Iowa, 1971-1980
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Report on a review of selected general and application controls over the University of Northern Iowa Student Information System for the period June 12, 2012 through July 16, 2012
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Report on a review of selected general and application controls over the State University of Iowa ePost and Effort Reporting systems for the period May 29, 2013 through July 19, 2013
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IRENE’s mission is to improve the health and well-being of Iowans through collaboration in practice-based research on questions important to primary care physicians and their patients. IRENE’s purpose is to create and foster a network of research collaboration between the academic medical center and primary care physicians through out the state of Iowa with a particular focus on improving rural health.
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IRENE’s mission is to improve the health and well-being of Iowans through collaboration in practice-based research on questions important to primary care physicians and their patients. IRENE’s purpose is to create and foster a network of research collaboration between the academic medical center and primary care physicians through out the state of Iowa with a particular focus on improving rural health.
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Newsletter from the University of Iowa School of Library and Information Science.
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Newsletter from the University of Iowa School of Library and Information Science.