Wilhem, Mignon und Lothario, Opernszene, Gruppenbildnis, in: Ambroise Thomas: Mignon, 3. Akt, Scène de la Prière

Signatur des Originals: S 36/G03812

Philine, Mignon {[u.a.], Opernszene, Gruppenbildnis, in: Ambroise Thomas: Mignon, 2. Akt, Polonaise de Titania

Signatur des Originals: S 36/G03813

Opernszene, in: Ambroise Thomas: Le Roman dÈlvire

Signatur des Originals: S 36/G03814

Titelblatt mit Szenenbildern zu: G.W. Marks: Pot-Pourri aus Mignon (Ambroise Thomas)

Signatur des Originals: S 36/G03849

Christine Nilsson als Ophélie, Rollenbild, in: Ambroise Thomas: Hamlet

Signatur des Originals: S 36/G04273

Ambroise Thomas, Brustbild

Signatur des Originals: S 36/G04423

Ms. Ff. S. Th. v. Soemmerring (Ausst. 66) - Stammbuch des Samuel Thomas von Soemmerring

Vorbesitzer: Samuel Thomas von Soemmerring; Sophie von Soemmerring; Akzessionsnummer: 2904/10;

Allgemeines Vieharzneibuch, oder des alten Schäfers Thomas seine Kuren an Rindvieh, Schweinen, Schaafen, Ziegen und den übrigen Hausthieren

von ihm selbst in seiner Mund- und Schreibart beschrieben und zum Nutzen seiner Nebenmenschen hrsg. von seinem Sohne dem Schäfer Thomas in Weißenborn

Vital function for PRELI and essential requirement for its LEA motif

Proteins containing the late embryogenesis abundant (LEA) motif comprise an evolutionarily conserved family, long postulated to protect plant embryos from stress and death. However, the significance of LEA-containing proteins and the mechanisms behind their function remain undetermined. Here we show that PRELI, a mammalian protein that possesses tandem repeats of the LEA motif, can protect cells against staurosporine, TNF-α or UV irradiation-induced apoptosis. We found that key to PRELI-dependent mechanisms that promote cell resistance to death are the stabilization of the respiratory chain, upholding of mitochondrial membrane potential and retention of apoptogenic molecules. By in vitro and in vivo studies, we also show that the expression of mutant PRELI/LEA- proteins lacking the LEA motif, results in the complete loss of PRELI's anti-apoptotic functions. Collectively, our data uncover a new molecular player in the control of apoptosis and support the hypothesis that LEA-containing proteins are evolutionarily conserved cell protectors against stress and death. ^

An analysis of the effects of a peer mentor program and other factors on HIV patients' retention in care and clinical outcomes at Thomas Street Health Clinic, Houston Texas

Research examining programs designed to retain patients in health care focus on repeated interactions between outreach workers and patients (Bradford et al. 2007; Cheever 2007). The purpose of this study was to determine if patients who are peer-mentored at their intake exam remain in care longer and attend more physicians' visits than those who were not mentored. Using patients' medical records and a previously created mentor database, the study determined how many patients attended their intake visit but subsequently failed to establish regular care. The cohort study examined risk factors for establishing care, determined if patients lacking a peer mentor failed to establish care more than peer mentor assisted patients, and subsequently if peer mentored patients had better health outcomes. The sample consists of 1639 patients who were entered into the Thomas Street Patient Mentor Database between May 2005 and June 2007. The assignment to the mentored group was haphazardly conducted based on mentor availability. The data from the Mentor Database was then analyzed using descriptive statistical software (SPSS version 15; SPSS Inc., Chicago, Illinois, USA). Results indicated that patients who had a mentor at intake were more likely to return for primary care HIV visits at 90 and 180 days. Mentored patients also were more likely to be prescribed ART within 180 days from intake. Other risk factors that impacted remaining in care included gender, previous care status, time from diagnosis to intake visit, and intravenous drug use. Clinical health outcomes did not differ significantly between groups. This supports that mentoring did improve outcomes. Continuing to use peer-mentoring programs for HIV care may help in increasing retention of patients in care and improving patients' health in a cost effective manner. Future research on the effects of peer mentoring on mentors, and effects of concordance of mentor and patient demographics may help to further improve peer-mentoring programs. ^