Programa de Alimentación Escolar de Uruguay: su impacto nutricional y educacional

Incluye Bibliografía

A fuga dupla luso-brasileira durante os séculos XVIII e XIX

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

MVC-RA: múltiplas visões coordenadas em ambientes de realidade aumentada

Versa sobre a aplicação das características de um ambiente de realidade aumentada, tais como: interação fácil e intuitiva, e grande espaço para visualização de dados, na implementação, interação e visualização de múltiplas visões de dados coordenadas. As múltiplas visões de dados permitem que o usuário realize uma melhor análise dos dados sobre diferentes aspectos, e a coordenação entre as múltiplas visões tem o objetivo de diminuir a sobrecarga oogniriva conferida ao usuário. O ambiente aumentado foi concebido através do ARToolKit, a interação se dá através de uma interface baseada em cartões marcadores. A técnica implementada foi Dispersão de Dados 3D, acompanhada de uma diversidade de filtros e configurações para as visões de dados. Por fim, são apresentados alguns ensaios de usabilidade preliminares do protótipo desenvolvido.

A formação de professores no curso de história da Universidade Federal do Pará: uma análise do projeto político pedagógico

O presente estudo apresenta como temática a formação de professores e busca investigar a seguinte problemática: qual o tratamento dado à formação o de professores para atuar na educação o básica a partir do atual projeto político pedagógico do curso de História da UFPA Buscamos compreender como se organiza a proposta curricular desse curso e como abordada a formação para a docência no referido PPP deste curso. A investigação se constituiu num estudo qualitativo com subsídio teórico de autores do campo historiográfico, do currículo e da formação docente. Adotamos uma análise documental e utilizamos documentos oficiais do CNE, como as DCN para os Cursos de Graduação em História, as DCN para os cursos de Formação de Professores da Educação o Básica e outros com abrangência interna na UFPA, para compreender as suas influências sobre o PPP do curso investigado, que carrega as proposições formativas para o profissional de História nesta IES. Analisando o PPP do curso de História verificamos que a perspectiva formativa no curso investigado ancora-se na formação do professor-historiador, aproximando-se do modelo de formação do professor-pesquisador, preconizado pelas DCN, para a Formação de Professores; entretanto, não identificamos os meios epistemológicos e práticos para a execução deste propósito de formação docente na configuração da estrutura curricular, principalmente quanto ao desenvolvimento de pesquisas sobre o fenômeno educacional. Identificamos, também, que o tratamento do conhecimento pedagógico, imprescindível na formação docente para atuar na Educação Básica, aparece de maneira secundária na estrutura curricular analisada. Portanto, inferimos que o conhecimento histórico assume a prioridade no desenvolvimento do curso investigado nos remetendo que a importância da formação se concentra no historiador, em detrimento da formação do professor.

Estrutura populacional de Oeceoclades maculata Lindl. (Orchidaceae), em um mosaico vegetacional (FEENA) da Floresta Estadual Edmundo Navarro de Andrade, Rio Claro, São Paulo

O objetivo do presente estudo foi avaliar a estrutura de população de O. maculata, através de sua distribuição espacial e estrutura de habitat, comparando características físicas e biológicas em diferentes fisionomias de Pinus spp. e Eucalyptus spp.. Foram montadas 86 parcelas de 5m por 10m, distribuídas uniformemente entre 4 áreas pré-estabelecidas de fisionomias distintas. Os indivíduos levantados foram separados em duas classes etárias, jovens e adultos, e contabilizou-se a taxa de predação, número de pseudobulbos e número de folhas. Os parâmetros ambientais avaliados foram cobertura herbácea, densidade de dossel, luminosidade e umidade de serrapilheira. A espécie apresentou densidades bastante elevadas nas áreas de plantios de eucalipto (1224 e 1733 indivíduos por hectare) e baixas nos plantios de pinus (88 e 26 individuos por hectare) o que levou as análises a se concentrarem nas fisionomias compostas por eucaliptos. O padrão de distribuição da espécie foi o agregado em todos os ambientes. Indivíduos adultos apresentaram significativamente um número médio de pseudobulbos maior que indivíduos jovens (Mann-Whitney; U = 24248.500; p<0,001), porém a diferença no número de folhas não foi significativa. A taxa de predação foliar em O. maculata entre as áreas de eucaliptos apresentou variação significativa. A variação do total de folhas predadas foi confirmada pelo teste Qui-quadrado de Pearson (X²=115.487; gl=1; p<0.001). A comparação de médias, com base no teste de Kruskal-Wallis, para cobertura de dossel (H(3,N=102)=28,534 p<0,001) e cobertura herbácea H(3,N=94)=28,246, p<0,001, mostrou taxas menores nas áreas de eucalipto. A umidade da serrapilheira foi menor (36,5%) nos locais onde a espécie apresentou agrupamentos, quando comparada aos locais de ausência (47,5%). Oeceoclades maculata Lindl. possui grande capacidade para colonizar ambientes... (Resumo completo, clicar acesso eletrônico abaixo)

Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-Driven Th17 response

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Educação e políticas públicas para o idoso

The ‘Estatuto do Idoso’ (senior citizen statute), Brazilian federal law promulgated in 2003, defines senior citizen as the person with 60 years old, or more. Revered as a landmark recognition of the senior´s rights, it guarantees, among others, the right of education. According to the statutory provisions, the education is personal right of the elderly person and must be assured with absolute priority by the State, the family, the society, as well by entities. However, in practice, just few senior citizens enjoy the right of education, since this policy has not been developed with focus in the old age, since educational practices are aimed, in most cases, to the younger age groups. Nevertheless, some initiatives seek to invest in the education for the elderly, like happens with the University of the Third Age (U3A). Although this kind of initiatives have been reason of celebration such projects should be enforced and consolidated as an object of better political investment to enlarge the access to the education right to the senior citizens in general. Due to the visibility achieved by the senior population, a possible way to the establishment of services in the area of education, would be the formation of partnerships between educational institutions that understand old age as a potential expansion of cultural goods and production of knowledge.

Feeding habits of Guiana dolphins, Sotalia guianensis, from south-eastern Brazil: new items and a knowledge review

This study presents new information on feeding habits of Guiana dolphins, Sotalia guianensis, in south-eastern Brazil, together with new regression equations to evaluate the weight and length of fish from otoliths, showing an overview on the knowledge about this species' diet in this area. Eighteen stomach contents had been analysed and compared to 180 samples collected in another eight feeding studies. The analysed specimens were either incidentally caught in gillnets used in coastal waters by the fleet based in the Cananeia main harbour (25 degrees 00'S 47 degrees 55'W), south of Sao Paulo State, or found dead in inner waters of the Cananeia estuary between 2003 and 2009. Based on the index of relative importance analysis, the most important fish species were the banded croaker, Paralonchurus brasiliensis. Doryteuthis plei was the most representative cephalopod species. Stellifer rastrifer was the most important fish species observed in dolphins in inner estuarine waters and P. brasiliensis in recovered dolphins from coastal waters. Loliguncula brevis is the only cephalopod species reported from dolphins found in inner estuarine waters up to date. Doryteuthis plei was the most important cephalopod species observed in coastal dolphins. When considering other feeding studies, the most representative fish family in the diet of S. guianensis was Sciaenidae, which is mainly represented by demersal fishes. The main preys of S. guianensis are abundant in the studied areas, which may indicate an opportunistic feeding habit. The majority of them are not the most important target species by the commercial fishery in south-eastern Brazil.

The Prelude from Suite for solo Piano Le Tombeau de Couperin by Maurice Ravel: compositional and interpretive considerations

This article, part of a doctoral research conducted at the Department of Music of the ECA/USP/FAPESP aims to elucidate compositional and technical procedures in the Prelude from the suite Le Tombeau de Couperin (1914-1917) by french composer Maurice Ravel. Such procedures are traced back to French barroque composer Francois Couperin (1668-1733) harpsichord pieces, and are translated by Ravel to the modern piano. Thus, by studying the works for harpsichord by Couperin it was possible to see a kind of fusion of two languages and two instrumental techniques apart in time. This fusion of languages poses several interpretive questions.

B Lymphocyte-Induced Maturation Protein-1 Contributes to Intestinal Mucosa Homeostasis by Limiting the Number of IL-17-Producing CD4(+) T Cells

The transcription factor B lymphocyte induced maturation protein-1 (Blimp-1) plays important roles in embryonic development and immunity. Blimp-1 is required for the differentiation of plasma cells, and mice with T cell specific deletion of Blimp-1 (Blimp-1CKO mice) develop a fatal inflammatory response in the colon. Previous work demonstrated that lack of Blimp-1 in CD4(+) and CD8(+) T cells leads to intrinsic functional defects, but little is known about the functional role of Blimp-1 in regulating differentiation of Th cells in vivo and their contribution to the chronic intestinal inflammation observed in the Blimp1CKO mice. In this study, we show that Blimp-1 is required to restrain the production of the inflammatory cytokine IL-17 by Th cells in vivo. Blimp-1CKO mice have greater numbers of IL-17 producing TCR beta(+)CD4(+)cells in lymphoid organs and in the intestinal mucosa. The increase in IL-17 producing cells was not restored to normal levels in wild-type and Blimp-1CKO mixed bone marrow chimeric mice, suggesting an intrinsic role for Blimp-1 in constraining the production of IL-17 in vivo. The observation that Blimp-1 deficient CD4(+) T cells are more prone to differentiate into IL-17(+)/IFN-gamma(+) cells and cause severe colitis when transferred to Rag1-deficient mice provides further evidence that Blimp-1 represses IL-17 production. Analysis of Blimp-1 expression at the single cell level during Th differentiation reveals that Blimp-1 expression is induced in Th1 and Th2 but repressed by TGF-beta in Th17 cells. Collectively, the results described here establish a new role for Blimp-1 in regulating IL-17 production in vivo. The Journal of Immunology, 2012,189: 5682-5693.

Chemical Chaperones Curcumin and 4-Phenylbutyric Acid Improve Secretion of Mutant Factor H R127H by Fibroblasts from a Factor H-Deficient Patient

Factor H (FH) is one of the most important regulatory proteins of the alternative pathway of the complement system. Patients with FH deficiency have a higher risk for development of infections and kidney diseases because of the uncontrolled activation and subsequent depletion of the central regulatory component C3 of the complement system. In this study, we investigated the consequences of the Arg(127)His mutation in FH (FHR127H) previously described in an FH-deficient patient, on the secretion of this protein by skin fibroblasts in vitro. We observed that, although the patient cells stimulated with IFN-gamma were able to synthesize FHR127H, the mutant protein was largely retained within the endoplasmic reticulum (ER), whereas normal human fibroblasts stimulated with IFN-gamma secrete FH without retention in the ER. Moreover, the retention of FHR127H provoked enlargement of ER cisterns after treatment with IFN-gamma. A similar ER retention was observed in Cos-7 cells expressing the mutant FHR127H protein. Despite this deficiency in secretion, we show that the FHR127H mutant is capable of functioning as a cofactor in the Factor I-mediated cleavage of C3. We then evaluated whether a treatment could increase the secretion of FH, and observed that the patient's fibroblasts treated with the chemical chaperones 4-phenylbutiric acid or curcumin increased the secretion rate of FH. We propose that these chemical chaperones could be used as alternative therapeutic agents to increase FH plasma levels in FH-deficient patients caused by secretion delay of this regulatory protein. The Journal of Immunology, 2012, 189: 3242-3248.

Cutting Edge: Brazilian Pemphigus Foliaceus Anti-Desmoglein 1 Autoantibodies Cross-React with Sand Fly Salivary LJM11 Antigen

The environmental factors that contribute to the development of autoimmune diseases are largely unknown. Endemic pemphigus foliaceus in humans, known as Fogo Selvagem (FS) in Brazil, is mediated by pathogenic IgG4 autoantibodies against desmoglein 1 (Dsg1). Clusters of FS overlap with those of leishmaniasis, a disease transmitted by sand fly (Lutzomyia longipalpis) bites. In this study, we show that salivary Ags from the sand fly, and specifically the LJM11 salivary protein, are recognized by FS Abs. Anti-Dsg1 monoclonal autoantibodies derived from FS patients also cross-react with LJM11. Mice immunized with LJM11 generate anti-Dsg1 Abs. Thus, insect bites may deliver salivary Ags that initiate a cross-reactive IgG4 Ab response in genetically susceptible individuals and lead to subsequent FS. Our findings establish a clear relationship between an environmental, noninfectious Ag and the development of potentially pathogenic autoantibodies in an autoimmune disease. The Journal of Immunology, 2012, 189: 1535-1539.