A Model of Ischemia-Induced Neuroblast Activation in the Adult Subventricular Zone

12 p.

The Role of the Subthalamic Nucleus in L-DOPA Induced Dyskinesia in 6-Hydroxydopamine Lesioned Rats

14 p.

Oscillatory Flow Induced Hydrodynamic Forces upon a Pipeline near Erosive Sandy Seabed

An experimental study of the properties of hydrodynamic forces upon a marine pipeline is presented in this paper, in the equilibrium scour conditions for various Keulegan-Carpenter numbers and various initial relative gaps between pipeline and the erosive sandy seabed. The tests are conducted in a U-shaped oscillatory water tunnel with a sand box located at the bottom of the test section. According to the experimental results, the maximum horizontal forces on the pipelines with an initial gap to seabed will decrease to some extent due to scouring process. For engineering appliances, it seems safer to estimate wave induced forces on pipelines under the assumption that seabed is plane. However, it should be noticed that great changes would be brought to the frequency properties of lift forces because of the sandy scour beneath the pipeline, which occurs for certain KC numbers.

The Effects of Backfill Soil Properties on Wave-induced Pore Pressures around a Trenched Pipeline

Offshore pipelines are always trenched into seabed to reduce wave-induced forces and thereby to enhance their stability. The trenches are generally backfilled either by in-site sediments or by depositing selected backfill materials over the pipeline from bottom-dump barge. The actual waves in shallow water zone are always characterized as nonlinear. The proper evaluation of the wave-induced pressures upon pipeline is important for coastal geotechnical engineers. However, most previous investigations of the wave–seabed–pipe interaction problem have been concerned only with a single sediment layer and linear wave loading. In this paper, based on Biot’s consolidation theory, a two-dimensional finite element model is developed to investigate non-linear wave induced pore pressures around trenched pipeline. The influences of the permeability of backfill soil and the geometry profiles of trenches upon soil responses around pipeline are studied respectively.

Physical Modeling of Current-Induced Seabed Scour around a Vibrating Submarine Pipeline

Most of the existing researches either focus on vortex-induced-vibrations (VIV) of a pipeline near a rigid boundary, or on seabed scour around a fixed pipeline. In the fields, pipeline vibration and seabed scour are actually always coupled. Based on the similarity analysis, a series of tests were conducted with a hydro-elastic facility to investigate the influence of pipe vibration on the local scour and the effects of scour process on the pipeline dynamic responses. Experimental results indicate that, there exist two phases in the process of sand scouring around the pipeline with small embedment, i.e. Phase I: scour beneath pipe without VIV, and Phase II: scour with VIV of pipe. It is also found that the gap-to-diameter ratio (e/D) has much effect upon the scour depth for the fixed pipes. For a given value of e/D, the vibrating pipes with close proximity to seabed may induce a deeper scour hole than the fixed ones. Within the examined gap-to-diameter ratio range (425 < e/D < 0.75), the influences of gap-to-diameter ratio on the maximum values of scour-depth for the case of vibrating pipes are not as much as those for the case of fixed pipes.

Catastrophic Rupture Induced Damage Coalescence in Heterogeneous Brittle Media

In heterogeneous brittle media, the evolution of damage is strongly influenced by the multiscale coupling effect. To better understand this effect, we perform a detailed investigation of the damage evolution, with particular attention focused on the catastrophe transition. We use an adaptive multiscale finite-element model (MFEM) to simulate the damage evolution and the catastrophic failure of heterogeneous brittle media. Both plane stress and plane strain cases are investigated for a heterogeneous medium whose initial shear strength follows the Weibull distribution. Damage is induced through the application of the Coulomb failure criterion to each element, and the element mesh is refined where the failure criterion is met. We found that as damage accumulates, there is a stronger and stronger nonlinear increase in stress and the stress redistribution distance. The coupling of the dynamic stress redistribution and the heterogeneity at different scales result in an inverse cascade of damage cluster size, which represents rapid coalescence of damage at the catastrophe transition.

Shock-Induced Dust Cloud Over a Deposit Layer of Fine Particles

The present paper investigates particle density pro les of a dust cloud induced by a normal shock wave moving at a constant speed along a at surface deposited with ne particles. In shock-fixxed coordinates, numerical simulation of ow structures of the carrier- and dispersed- phases was performed for the M = 2 case. The neness and non-uniformity of the particle size are taken into account and their effcts on the dust cloud are discussed in detail.

The induced flow field by internal solitary wave and its action on cylindrical piles in the stratified ocean

The induced flow fields by internal solitary waves and its actions on cylindrical piles in density stratified ocean with a basic density profile and a basic velocity profile are investigated. Some results, such as the time evolution of flow fields and hydrodynamic forces on the piles are yielded both by theoretical analysis and numerical calculation for general and specific cases. Several kinds of ambient sea conditions of the South China Sea are specified for numerical simulation. Moreover, the effects of relative density difference, depth ratio and wave steepness on maximal total force and total torque are analyzed.