Avvicinamento alla storia dell'architettura giapponese. Dal periodo Nara al periodo Meiji

The book analyzes the history of Japanese Architecture between Nara Period (710-784) and Meiji Period (1867-1912). The book is organized in two part: "The History" and "The Cultural Heritage" with a reflexion about the restoration of the Temples and Shrines. The book is the result of an international research work at the Kyoto University.

Comunicazione urbana nelle città storiche del Sol Levante: l'esperienza di Kyoto tra tradizione e innovazione

The book collects the Papers (from Europe, Asia and Latin America) presented at the Workshop organized by the ICOMOS International Committee in Historic Towns and Villages (CIVVIH) and by ICOMOS Italy in Palazzo Coppini (branch of Fondazione Romualdo del Bianco) in Florence (March 3-4, 2016) and focus on the comparison of different propositions of digital urban signage to realize a good quality of the “visit experience” in the historical towns, not only as urban marketing, but of a authenticity genuine culture. The urban culture founded on the identity and authenticity of every historical towns and their multilayered history must be the objective of an tourism of culture for the inhabitants and the visitors. The book focused its interest on the outstanding existing urban assets in Europe, Asia and Latin America, and heritage not sufficiently promoted.

Relação entre medidas ultrassônicas e da carcaça de bubalinos Murrah abatidos em diferentes períodos de confinamento

Os objetivos neste trabalho foram estimar as correlações entre medidas obtidas por ultrassonografia e na carcaça e acompanhar o desenvolvimento da área de olho-de-lombo e a deposição de gordura de búfalos em diferentes períodos de confinamento. Foram utilizados 20 bubalinos da raça Murrah, castrados, abatidos aos 75, 100, 125 ou 150 dias de confinamento. As medidas realizadas foram área de olho-de-lombo, espessura de gordura subcutânea do dorso e espessura de gordura da garupa, mensuradas por ultrassonografia quando os búfalos atingiram o tempo de abate e na carcaça, após o abate. A espessura de gordura subcutânea da carcaça foi avaliada utilizando-se paquímetro e a área de olho-de-lombo da carcaça, régua do quadrante de pontos. O período de confinamento apresentou efeito linear crescente na área de olho-de-lombo e nas espessuras de gordura do dorso e da garupa avaliadas por ultrassom e na carcaça. O efeito linear positivo entre 75 e 150 dias de confinamento, tanto para a área de olho-de-lombo como para espessura de gordura medidas no dorso e na garupa, comprovou que os animais ainda não haviam atingido a maturidade. As correlações entre as medidas obtidas por ultrassom e na carcaça foram 0,82 para área de olho-de-lombo e 0,85 para espessura de gordura subcutânea no dorso. As características de carcaça medidas por ultrassom em bubalinos apresentam boas correlações com as medidas realizadas na carcaça no momento do abate, o que permite, em bubalinos da raça Murrah castrados e oriundos de rebanho leiteiro, acompanhar as alterações dessas características durante o desenvolvimento.

Le patrimoine culturel universitaire: une méthodologie pour la conservation et la valorisation des biens culturels mobiliers. Le cas de l'Instituto Superior José Antonio Echeverría à la CUJAE - La Havane

Une préoccupation importante pour le patrimoine culturel universitaire vient de se développer en Europe depuis les années 1980. Dans ce riche patrimoine sont inclus les biens mobiliers de valeur historique, scientifico-technique, académique, documentaire, artistique, architecturale et urbaine. Le continent européen a développé durant ces dernières années des actions significatives qui comprennent la création d’organisations, de comités à caractère international, ainsi que la rédaction de recommandations et règlements au niveau européen et institutionnel. Plusieurs universités ont pris des initiatives dans le domaine de la conservation et de la valorisation. À Cuba, il existe un grand intérêt pour le patrimoine culturel de la nation. Malgré la situation économique difficile depuis plusieurs années, Cuba a réussi des bons résultats dans la gestion des centres historiques et des biens patrimoniaux de la nation. Cependant, la thématique liée au patrimoine universitaire est encore peu discutée sur le territoire national, malgré depuis 2010, des actions pour étudier ce patrimoine sont mis en oeuvre grâce aux initiatives des universités de la capitale cubaine. Notre étude de cas, l’Instituto Superior Politécnico José Antonio Echeverría, appartenant au campus CUJAE1, fondé en 1964, a produit un patrimoine culturel universitaire de valeur scientifique, artistique et documentaire qui le distingue des autres universités. Malheureusement, ils existent plusieurs problèmes qui affectent les biens culturels mobiliers de l’ISPJAE et son campus. À partir de la situation actuelle, nous proposons une méthodologie en faveur de la conservation et la valorisation de ses biens, basée sur l’étude des tendances actuelles dans les universités européennes et cubaines étudiées. Les actions proposées favoriseront aussi les biens immobiliers, en tenant compte qu’ils ont un fort lien avec ceux mobiliers; ABSTRACT: An important concern for the university cultural heritage has just developed in Europe since the 1980s. The real asses of historic, scientific-technical, academic, documentary, artistic, architectural values are included in these rich heritages. The European continent developed during the last years significant actions which include the creation of organizations, committees with international character, as well as the writing of recommendations and regulations at the European and institutional level. Several universities took initiatives in the fields of the preservation and the valuation. In Cuba, there is a big interest for the cultural heritage of the nation. In spite of the difficult economic situation for several years, Cuba made a success of good results in the management of the historic centers and the patrimonial asses of the nation. However, the subject related to the university heritage is again little discussed in the national territory in spite of since 2010, several actions to study this heritage are implemented, thanks to the initiatives of the universities of the Cuban capital. Our case of study, Instituto Superior Politécnico José Antonio Echeverría, belonging to the campus CUJAE, established in 1964, produced a university cultural heritage of the scientific, artistic and documentary value, which distinguishes it from other universities. Unfortunately, there are several problems, which affect the real cultural asses of the ISPJAE and its campus. From the current situation, we propose a methodology in favor of the preservation and the valuation of its properties, based on the study of the current trends in the studied European and Cuban universities. The proposed actions will also favor the real property, taking into account that they have a strong link with those movable cultural asses; RIASSUNTO: Una preoccupazione importante per il patrimonio culturale universitario inizia a svilupparsi in Europa dagli anni 1980. In questo ricco patrimonio sono inclusi i beni mobili di valore storico, scientifico-tenico, accademico, documentario, artistico, architettonico e urbano. Il continente europeo ha sviluppato durante questi ultimi anni delle azioni significative che comprendono la creazione di organizazioni, di comitati internazionali, così come la redazione di raccomandazioni e regolamenti a livello europeo e istituzionale. Molte università hanno intrapreso delle iniziative nella conservazione e nella valorizzazione. A Cuba esiste un grande interesse per il patrimonio culturale della nazione. Malgrado la difficile situazione economica da molti anni Cuba ha ottenuto dei buoni risultati nella gestione di centri storici e di beni patrimoniali del Paese. Comunque, la tematica relativa al patrimonio universitario è ancora poco discussa anche se dal 2010 siano messe in opera delle azioni per studiare questo patrimonio, grazie alle iniziative di alcune università della capitale cubana. Il nostro caso di studio, l’Instituto Superior Politécnico José Antonio Echeverría –ISPJAE-, appartenente al campus CUJAE fondato nel 1964, ha prodotto un patrimonio culturale universitario di valore scientifico, artistico e documentale che la distinguono delle altre università. Purtroppo, esistono molti problemi che influenzano i beni culturali mobili dell’ISPJAE e del suo campus. A partire della situazione attuale e facendo parte di questa ricerca, si propone una metodologia a favore della conservazione e della valorizzazione dei loro beni fondata sullo studio delle tendenze attuali in università europee e cubane. Alcune delle azioni proposte sono finalizzate e destinate anche ai beni immobili, tenendo conto che questi hanno un forte rapporto con i beni mobili.

A testetlen eszközök jelentősége a vállalat működésében, pénzügyi teljesítményében és piaci értékelésében

Az elmúlt két évtizedben jelentősen növekedett a testetlen eszközök (intangible assets) szerepe a vállalatok működésében, pénzügyi teljesítményében és versenyképességében. A vállalatok mind nagyobb mértékben alapozzák tevékenységüket a testetlen vagyon elemeire, miközben a dologi eszközök jelentősége mérséklődik. A vállalatspecifikus testetlen eszközök a tudás és az információ köré összpontosulnak, spill-over hatással rendelkeznek, és felhalmozódásuk sajátos. A testetlen eszközök egyediségének és az általuk várhatóan generált jövőbeni pénzáramsor nehéz előrejelezhetőségének következtében értékelésük számottevő bizonytalanságot és szubjektivitást rejt magában; a befektetők azonban rendszerint magas piaci értéket társítanak hozzájuk, minthogy a piaci siker meghatározóinak tekintik őket. A vállalatok benső és piaci értékének eltérését elemző elméletek egy csoportja szerint pedig a testetlen eszközöknek szignifikáns hatása van a két érték különbségére. A szerző tanulmányában rámutat a testetlen eszközök vállalati működésben és versenyképességben betöltött szerepére, a dologi vagyon elemeitől eltérő tulajdonságaira, értékelésére és a vállalatok piaci értékére gyakorolt hatására.

Assessment of a best practise approach for the attribution and authentication of paintings

The ever-growing interest in scientific techniques, able to characterise the materials and rediscover the steps behind the execution of a painting, makes them widely accepted in its investigation. This research discusses issues emerging from attribution and authentication studies and proposes best practise for the characterisation of materials and techniques, favouring the contextualisation of the results in an integrated approach; the work aims to systematically classify paintings in categories that aid the examination of objects. A first grouping of paintings is based on the information initially available on them, identifying four categories. A focus of this study is the examination of case studies, spanning from the 16th to the 20th century, to evaluate and validate different protocols associated to each category, to show problems arising from paintings and explain advantages and limits of the approach. The research methodology incorporates a combined set of scientific techniques (non-invasive, such as technical imaging and XRF, micro-invasive, such as optical microscopy, SEM-EDS, FTIR, Raman microscopy and in one case radiocarbon dating) to answer the questions and, if necessary for the classification, exhaustively characterise the materials of the paintings, as the creation and contribution of shared technical databases related to various artists and their evolution over time is an objective tool that benefits this kind of study. The reliability of a close collaboration among different professionals is an essential aspect of this research to comprehensively study a painting, as the integration of stylistic, documentary and provenance studies corroborates the scientific findings and helps in the successful contextualisation of the results and the reconstruction of the history of the object.

Applications of metrological techniques for clinical implementation of dosimetry and radiobiology in molecular radiotherapy

Molecular radiotherapy (MRT) is a fast developing and promising treatment for metastasised neuroendocrine tumours. Efficacy of MRT is based on the capability to selectively "deliver" radiation to tumour cells, minimizing administered dose to normal tissues. Outcome of MRT depends on the individual patient characteristics. For that reason, personalized treatment planning is important to improve outcomes of therapy. Dosimetry plays a key role in this setting, as it is the main physical quantity related to radiation effects on cells. Dosimetry in MRT consists in a complex series of procedures ranging from imaging quantification to dose calculation. This doctoral thesis focused on several aspects concerning the clinical implementation of absorbed dose calculations in MRT. Accuracy of SPECT/CT quantification was assessed in order to determine the optimal reconstruction parameters. A model of PVE correction was developed in order to improve the activity quantification in small volume, such us lesions in clinical patterns. Advanced dosimetric methods were compared with the aim of defining the most accurate modality, applicable in clinical routine. Also, for the first time on a large number of clinical cases, the overall uncertainty of tumour dose calculation was assessed. As part of the MRTDosimetry project, protocols for calibration of SPECT/CT systems and implementation of dosimetry were drawn up in order to provide standard guidelines to the clinics offering MRT. To estimate the risk of experiencing radio-toxicity side effects and the chance of inducing damage on neoplastic cells is crucial for patient selection and treatment planning. In this thesis, the NTCP and TCP models were derived based on clinical data as help to clinicians to decide the pharmaceutical dosage in relation to the therapy control and the limitation of damage to healthy tissues. Moreover, a model for tumour response prediction based on Machine Learning analysis was developed.

Exploring New Material and Analytical Method for Characterization and Conservation of Artifacts

In this dissertation, we focus on developing new green bio-based gel systems and evaluating both the cleaning efficiency and the release of residues on the treated surface, different micro or no destructive techniques, such as optical microscopy, TGA, FTIR spectroscopy, HS-SPME and micro-Spatially Offset Raman spectroscopy (micro-SORS) were tested, proposing advanced analytical protocols. In the first part, a ternary PHB-DMC/BD gel system composed by biodiesel, dimethyl carbonate and poly-3 hydroxybutyrate was developed for cleaning of wax-based coatings applied on indoor bronze. The evaluation of the cleaning efficacy of the gel was carried out on a standard bronze sample which covered a layer of beeswax by restores of Opificio delle Pietre Dure in Florence, and a real case precious indoor bronze sculpture Pulpito della Passione attributed to Donatello. Results obtained by FTIR analysis showed an efficient removal of the wax coating. In the second part, two new kinds of combined gels based on electrospun tissues (PVA and nylon) and PHB-GVL gel were developed for removal of dammar varnish from painting. The electrospun tissue combined gels exhibited good mechanical property, and showed good efficient in cleaning over normal gel. In the third part, green deep eutectic solvent which consists urea and choline chloride was proposed to produce the rigid gel with agar for the removal of proteinaceous coating from oil painting. Rabbit glue and whole egg decorated oil painting mock-ups were selected for evaluating its cleaning efficiency, results obtained by ATR analysis showed the DES-agar gel has good cleaning performance. Furthermore, we proposed micro-SORS as a valuable alternative non-destructive method to explore the DES diffusion on painting mock-up. As a result, the micro-SORS was successful applied for monitoring the liquid diffusion behavior in painting sub-layer, providing a great and useful instrument for noninvasive residues detection in the conservation field.

Environmental assessment of industrial chemical and primary sector processes from a life cycle perspective

During the PhD program in chemistry at the University of Bologna, the environmental sustainability of some industrial processes was studied through the application of the LCA methodology. The efforts were focused on the study of processes under development, in order to assess their environmental impacts to guide their transfer on an industrial scale. Processes that could meet the principles of Green Chemistry have been selected and their environmental benefits have been evaluated through a holistic approach. The use of renewable sources was assessed through the study of terephthalic acid production from biomass (which showed that only the use of waste can provide an environmental benefit) and a new process for biogas upgrading (whose potential is to act as a carbon capture technology). Furthermore, the basis for the development of a new methodology for the prediction of the environmental impact of ionic liquids has been laid. It has already shown good qualities in identifying impact trends, but further research on it is needed to obtain a more reliable and usable model. In the context of sustainable development that will not only be sector-specific, the environmental performance of some processes linked to the primary production sector has also been evaluated. The impacts of some organic farming practices in the wine production were analysed, the use of the Cereal Unit parameter was proposed as a functional unit for the comparison of different crop rotations, and the carbon footprint of school canteen meals was calculated. The results of the analyses confirm that sustainability in the industrial production sector should be assessed from a life cycle perspective, in order to consider all the flows involved during the different phases. In particular, it is necessary that environmental assessments adopt a cradle-to-gate approach, to avoid shifting the environmental burden from one phase to another.

Advanced Spectroscopy for the Study of Colourants in Cultural Heritage

Colourants are substances used to change the colour of something, and are classified in three typology of colorants: a) pigments, b) dyes, and c) lakes and hybrid pigments. Their identification is very important when studying cultural heritage; it gives information about the artistic technique, can help in dating, and offers insights on the condition of the object. Besides, the study of the degradation phenomena constitutes a framework for the preventive conservation strategies, provides evidence of the object's original appearance, and contributes to the authentication of works of art. However, the complexity of these systems makes it impossible to achieve a complete understanding using a single technique, making necessary a multi-analytical approach. This work focuses on the set-up and application of advanced spectroscopic methods for the study of colourants in cultural heritage. The first chapter presents the identification of modern synthetic organic pigments using Metal Underlayer-ATR (MU-ATR), and the characterization of synthetic dyes extracted from wool fibres using a combination of Thin Layer Chromatography (TLC) coupled to MU-ATR using AgI@Au plates. The second chapter presents the study of the effect of metallic Ag in the photo-oxidation process of orpiment, and the influence of the different factors, such as light and relative humidity. We used a combination of vibrational and synchrotron radiation-based X-ray microspectroscopy techniques: µ-ATR-FT-IR, µ-Raman, SR-µ-XRF, µ-XANES at S K-, Ag L3- and As K-edges and SR-µ-XRD. The third chapter presents the study of metal carboxylates in paintings, specifically on the formation of Zn and Pb carboxylates in three different binders: stand linseed oil, whole egg, and beeswax. We used micro-ATR-FT-IR, macro FT-IR in total reflection (rMA-FT-IR), portable Near-Infrared spectroscopy (NIR), macro X-ray Powder Diffraction (MA-XRPD), XRPD, and Gas Chromatography Mass-Spectrometry (GC-MS). For the data processing, we explored the data from rMA-FT-IR and NIR with the Principal Component Analysis (PCA).

1H NMR Relaxation Characterization Of Hydrates

To distinguish the components of NMR signals from hydrated materials and to monitor their evolution after the addition of water to the powders, during the first two days of hydration. To implement the 3 Tau Model in a MATLAB script, called 3TM, provided with a Graphical User Interface (GUI), to easily use the 3 Tau Model with NMRD profiles. The 3 Tau Model, developed a few years ago is used for interpreting the dispersion (NMRD profiles, dependence on the Larmor frequency) of the longitudinal relaxation times, for liquids confined in porous media. This model describes the molecular dynamics of confined molecules by introducing three characteristic correlation times and additional outputs.

Lo studio del microclima indoor per la conservazione preventiva del Patrimonio storico artistico e culturale

La conservazione preventiva degli edifici storici e dei beni custoditi al loro interno rappresenta una sfida ad oggi condivisa a livello internazionale. Tale conservazione dipende da numerose variabili, tra le quali il microclima indoor gioca un ruolo decisivo. Il fine di questa tesi è verificare come lo studio del microclima indoor, supportato dalla simulazione virtuale e dalla conoscenza storica delle evoluzioni dell’edificio stesso (legate a modifiche impiantistiche; architettoniche; d’uso; ecc., nel corso degli anni), costituiscano una base conoscitiva fondamentale, da cui architetti e restauratori possono partire per definire strategie specifiche, volte alla conservazione preventiva del Patrimonio. Per fare questo, l’autore presenta le indagini svolte per tre casi-studio: la Sala 33 della Reggia di Venaria Reale, in provincia di Torino, Italia; la Biblioteca Generale Storica dell’Università di Salamanca, in Spagna; il Portico della Gloria, nartece della Cattedrale di Santiago de Compostela, in Spagna. La metodologia definita e adottata per l’analisi e l’interpretazione dei dati di ciascun caso-studio ha previsto la comprensione e la messa in relazione tra: scelte costruttive; vicende evolutive delle singole architetture; fattori che ne determinano il microclima, letti (o ipotizzati) nelle relative modifiche diacroniche; degrado delle architetture e dei beni che sono custoditi in esse. Infine, uno degli esiti più innovativi della ricerca è stata la definizione di due indici di rischio: sono stati infatti definiti due nuovi indici (Heritage Microclimate Risk -HMR- e Predicted Risk of Damage -PRD-) legati al microclima degli edifici che ospitano beni e manufatti che costituiscono il patrimonio storico artistico e culturale. Tali indici sono stati definiti tenendo conto di tutte le variabili da cui il microclima dipende e dei fattori che ne determinano l’evolversi nel tempo e nello spazio.

Characterization of DNA sequence properties through network and statistical approaches

In this thesis we will see that the DNA sequence is constantly shaped by the interactions with its environment at multiple levels, showing footprints of DNA methylation, of its 3D organization and, in the case of bacteria, of the interaction with the host organisms. In the first chapter, we will see that analyzing the distribution of distances between consecutive dinucleotides of the same type along the sequence, we can detect epigenetic and structural footprints. In particular, we will see that CG distance distribution allows to distinguish among organisms of different biological complexity, depending on how much CG sites are involved in DNA methylation. Moreover, we will see that CG and TA can be described by the same fitting function, suggesting a relationship between the two. We will also provide an interpretation of the observed trend, simulating a positioning process guided by the presence and absence of memory. In the end, we will focus on TA distance distribution, characterizing deviations from the trend predicted by the best fitting function, and identifying specific patterns that might be related to peculiar mechanical properties of the DNA and also to epigenetic and structural processes. In the second chapter, we will see how we can map the 3D structure of the DNA onto its sequence. In particular, we devised a network-based algorithm that produces a genome assembly starting from its 3D configuration, using as inputs Hi-C contact maps. Specifically, we will see how we can identify the different chromosomes and reconstruct their sequences by exploiting the spectral properties of the Laplacian operator of a network. In the third chapter, we will see a novel method for source clustering and source attribution, based on a network approach, that allows to identify host-bacteria interaction starting from the detection of Single-Nucleotide Polymorphisms along the sequence of bacterial genomes.

Confronto dei metodi di conservazione della carta fra Italia e Cina : indagini scientifiche e tecniche di restauro per il materiale cartaceo

I metodi di conservazione per i materiali cartacei in Italia e in Cina sono nati in diversi contesti storici. L’idea di questo studio nasce dalla necessità di sviluppare analisi specifiche sul metodo di restauro cartaceo cinese, per introdurre metodi e tecnologie efficaci ed innovative.

Shaping transverse beam distributions by means of adiabatic crossing of resonances

Non-linear effects are responsible for peculiar phenomena in charged particles dynamics in circular accelerators. Recently, they have been used to propose novel beam manipulations where one can modify the transverse beam distribution in a controlled way, to fulfil the constraints posed by new applications. One example is the resonant beam splitting used at CERN for the Multi-Turn Extraction (MTE), to transfer proton beams from PS to SPS. The theoretical description of these effects relies on the formulation of the particle's dynamics in terms of Hamiltonian systems and symplectic maps, and on the theory of adiabatic invariance and resonant separatrix crossing. Close to resonance, new stable regions and new separatrices appear in the phase space. As non-linear effects do not preserve the Courant-Snyder invariant, it is possible for a particle to cross a separatrix, changing the value of its adiabatic invariant. This process opens the path to new beam manipulations. This thesis deals with various possible effects that can be used to shape the transverse beam dynamics, using 2D and 4D models of particles' motion. We show the possibility of splitting a beam using a resonant external exciter, or combining its action with MTE-like tune modulation close to resonance. Non-linear effects can also be used to cool a beam acting on its transverse beam distribution. We discuss the case of an annular beam distribution, showing that emittance can be reduced modulating amplitude and frequency of a resonant oscillating dipole. We then consider 4D models where, close to resonance, motion in the two transverse planes is coupled. This is exploited to operate on the transverse emittances with a 2D resonance crossing. Depending on the resonance, the result is an emittance exchange between the two planes, or an emittance sharing. These phenomena are described and understood in terms of adiabatic invariance theory.